| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J L Barr, G L Forste. Serotonergic neurotransmission in the ventral hippocampus is enhanced by corticosterone and altered by chronic amphetamine treatment. Neuroscience. vol 182. 2012-05-31. PMID:21420472. |
together, our results suggest that chronic amphetamine exposure reduces serotonergic neurotransmission, in part via alterations to glucocorticoid receptor-facilitation of serotonin release in the rat ventral hippocampus. |
2012-05-31 |
2023-08-12 |
rat |
| J A Wixey, H E Reinebrant, S J Spencer, K M Bulle. Efficacy of post-insult minocycline administration to alter long-term hypoxia-ischemia-induced damage to the serotonergic system in the immature rat brain. Neuroscience. vol 182. 2012-05-31. PMID:21440046. |
however the long-term efficacy of minocycline to prevent injury to a specific neuronal network, such as the serotonergic (5-hydroxytryptamine, 5-ht) system, is not known. |
2012-05-31 |
2023-08-12 |
rat |
| Perdita A Cheshire, David R William. Serotonergic involvement in levodopa-induced dyskinesias in Parkinson's disease. Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia. vol 19. issue 3. 2012-05-31. PMID:22249009. |
here, we review the evidence for serotonergic involvement in dyskinesias from animal and human data, and highlight some of the translational gaps which may explain why the success of serotonin autoreceptor agonists as anti-dyskinetic agents in experimental models has failed to be replicated in clinical trials. |
2012-05-31 |
2023-08-12 |
human |
| Catherine E Hagan, James O Schenk, John F Neumaie. The contribution of low-affinity transport mechanisms to serotonin clearance in synaptosomes. Synapse (New York, N.Y.). vol 65. issue 10. 2012-05-30. PMID:21437992. |
these findings, in conjunction with other studies, have important implications for understanding serotonergic disorders and may explain the variable efficacy and stability of patients' responses to antidepressants, such as the selective serotonin reuptake inhibitors. |
2012-05-30 |
2023-08-12 |
mouse |
| Fatemeh Talaei, Martina Schmidt, Robert H Hennin. Induction of VMAT-1 and TPH-1 expression induces vesicular accumulation of serotonin and protects cells and tissue from cooling/rewarming injury. PloS one. vol 7. issue 1. 2012-05-29. PMID:22253933. |
the vesicular serotonergic phenotype protects against hypothermic damage through re-uptake of serotonin inducing cbs mediated h₂s production both in cells and kidney slices. |
2012-05-29 |
2023-08-12 |
rat |
| Kinga Salat, Andrzej Moniczewski, Robert Salat, Monika Janaszek, Barbara Filipek, Barbara Malawska, Krzysztof Wieckowsk. Analgesic, anticonvulsant and antioxidant activities of 3-[4-(3-trifluoromethyl-phenyl)-piperazin-1-yl]-dihydrofuran-2-one dihydrochloride in mice. Pharmacology, biochemistry, and behavior. vol 101. issue 1. 2012-05-25. PMID:22227221. |
in vitro lpp1 has no affinity for gaba(a), opioidergic μ and serotonergic 5-ht(1a) receptors. |
2012-05-25 |
2023-08-12 |
mouse |
| Dominik Kiser, Ben Steemers, Igor Branchi, Judith R Homber. The reciprocal interaction between serotonin and social behaviour. Neuroscience and biobehavioral reviews. vol 36. issue 2. 2012-05-24. PMID:22206901. |
it is well recognized that 5-ht plays a key role in shaping social responses, and that the serotonergic system itself is highly responsive to social influences. |
2012-05-24 |
2023-08-12 |
monkey |
| Dominik Kiser, Ben Steemers, Igor Branchi, Judith R Homber. The reciprocal interaction between serotonin and social behaviour. Neuroscience and biobehavioral reviews. vol 36. issue 2. 2012-05-24. PMID:22206901. |
the studies here reviewed, selected using the pubmed search terms "social behaviour" and "serotonin", describe the effects of serotonergic gene variation and pharmacological manipulations in humans, monkeys, and rodents, and involve parental attachment and caregiving, social play, aggressiveness, cooperation, and sexual behaviour. |
2012-05-24 |
2023-08-12 |
monkey |
| S Josefin Dahlbom, Tobias Backström, Katrin Lundstedt-Enkel, Svante Winber. Aggression and monoamines: effects of sex and social rank in zebrafish (Danio rerio). Behavioural brain research. vol 228. issue 2. 2012-05-23. PMID:22192379. |
further, we found that dyadic agonistic interaction resulted in elevated brain serotonergic activity in subordinate zebrafish, as indicated by elevated hindbrain 5-hydroxyindoleacetic acid to serotonin ratios (5-hydroxyindolacetic acid (5-hiaa)/5-hydroxytryptamine (5-ht) ratios). |
2012-05-23 |
2023-08-12 |
zebrafish |
| Linlin Zhen, Jiejin Zhu, Xin Zhao, Wu Huang, Yiran An, Shan Li, Xia Du, Mengmeng Lin, Qiandong Wang, Ying Xu, Jianchun Pa. The antidepressant-like effect of fisetin involves the serotonergic and noradrenergic system. Behavioural brain research. vol 228. issue 2. 2012-05-23. PMID:22197297. |
two behavioral models, reserpine-induced hypothermia and ptosis, and p-chlorophenylalanine (pcpa)-induced depletion of serotonin, were used to explore the possible involvement of fisetin in the noradrenergic and serotonergic system. |
2012-05-23 |
2023-08-12 |
mouse |
| C Cirillo, P Vanden Berghe, J Tac. Role of serotonin in gastrointestinal physiology and pathology. Minerva endocrinologica. vol 36. issue 4. 2012-05-22. PMID:22322654. |
the wide range of pathophysiological actions exerted by 5-ht are mediated by several different serotonergic receptor types and subtypes. |
2012-05-22 |
2023-08-12 |
Not clear |
| C Cirillo, P Vanden Berghe, J Tac. Role of serotonin in gastrointestinal physiology and pathology. Minerva endocrinologica. vol 36. issue 4. 2012-05-22. PMID:22322654. |
therapeutic interventions aiming at modulating 5-ht signaling are mainly focused on the development of receptor agonists/antagonists, characterized by high affinity and selectivity for serotonergic receptors in the gut, to avoid the presence of adverse effects in the brain, where 5-ht is important in control mood. |
2012-05-22 |
2023-08-12 |
Not clear |
| Marios Politis, Clare Loane, Kit Wu, David J Brooks, Paola Piccin. Serotonergic mediated body mass index changes in Parkinson's disease. Neurobiology of disease. vol 43. issue 3. 2012-05-21. PMID:21624463. |
the serotonergic (5-ht) system has been proposed to regulate appetite and the 5-ht transporter (sert) is a key modulator of 5-ht metabolism. |
2012-05-21 |
2023-08-12 |
Not clear |
| Junko Yaguchi, Lynne M Angerer, Kazuo Inaba, Shunsuke Yaguch. Zinc finger homeobox is required for the differentiation of serotonergic neurons in the sea urchin embryo. Developmental biology. vol 363. issue 1. 2012-05-21. PMID:22210002. |
here, we report that zinc finger homeobox (zfhx1/z81) is expressed in serotonergic neural precursor cells, using double in situ hybridization screening with a serotonergic neural marker, tryptophan 5-hydroxylase (tph) encoding a serotonin synthase that is required for the differentiation of serotonergic neurons. |
2012-05-21 |
2023-08-12 |
Not clear |
| Ahmet Dogrul, Melik Seyrek, Emin Ozgur Akgul, Tuncer Cayci, Serdar Kahraman, Hayrunnisa Bola. Systemic paracetamol-induced analgesic and antihyperalgesic effects through activation of descending serotonergic pathways involving spinal 5-HT₇ receptors. European journal of pharmacology. vol 677. issue 1-3. 2012-05-17. PMID:22206817. |
although some studies have shown the essential role of descending serotonergic pathways and spinal 5-ht(1a), 5-ht(2a), or 5-ht(3) receptors in the antinociceptive effects of paracetamol, other studies have presented conflicting results, and the particular subtype of spinal 5-ht receptors involved in paracetamol-induced analgesia remains to be clarified. |
2012-05-17 |
2023-08-12 |
mouse |
| Ahmet Dogrul, Melik Seyrek, Emin Ozgur Akgul, Tuncer Cayci, Serdar Kahraman, Hayrunnisa Bola. Systemic paracetamol-induced analgesic and antihyperalgesic effects through activation of descending serotonergic pathways involving spinal 5-HT₇ receptors. European journal of pharmacology. vol 677. issue 1-3. 2012-05-17. PMID:22206817. |
recent studies have demonstrated the importance of spinal 5-ht(7) receptors in descending serotonergic pain inhibitory pathways. |
2012-05-17 |
2023-08-12 |
mouse |
| Ahmet Dogrul, Melik Seyrek, Emin Ozgur Akgul, Tuncer Cayci, Serdar Kahraman, Hayrunnisa Bola. Systemic paracetamol-induced analgesic and antihyperalgesic effects through activation of descending serotonergic pathways involving spinal 5-HT₇ receptors. European journal of pharmacology. vol 677. issue 1-3. 2012-05-17. PMID:22206817. |
in this study, we investigated the role of descending serotonergic pathways and spinal 5-ht(7) receptors compared with 5-ht(3) and 5-ht(2a) receptors in the antinociceptive and antihyperalgesic effects of paracetamol. |
2012-05-17 |
2023-08-12 |
mouse |
| Ahmet Dogrul, Melik Seyrek, Emin Ozgur Akgul, Tuncer Cayci, Serdar Kahraman, Hayrunnisa Bola. Systemic paracetamol-induced analgesic and antihyperalgesic effects through activation of descending serotonergic pathways involving spinal 5-HT₇ receptors. European journal of pharmacology. vol 677. issue 1-3. 2012-05-17. PMID:22206817. |
our findings suggest that systemic administration of paracetamol may activate descending serotonergic pathways and spinal 5-ht(7) receptors to produce a central antinociceptive and antihyperalgesic effects. |
2012-05-17 |
2023-08-12 |
mouse |
| Evan S Deneris, Steven C Wyle. Serotonergic transcriptional networks and potential importance to mental health. Nature neuroscience. vol 15. issue 4. 2012-05-16. PMID:22366757. |
transcription regulatory networks governing the genesis, maturation and maintenance of vertebrate brain serotonin (5-ht) neurons determine the level of serotonergic gene expression and signaling throughout an animal's lifespan. |
2012-05-16 |
2023-08-12 |
mouse |
| J David Glass, Allison J Brager, Adam C Stowie, Rebecca A Prosse. Cocaine modulates pathways for photic and nonphotic entrainment of the mammalian SCN circadian clock. American journal of physiology. Regulatory, integrative and comparative physiology. vol 302. issue 6. 2012-05-15. PMID:22218419. |
finally, pretreatment of scn slices for 2 h with a low concentration of serotonin agonist (to block subsequent serotonergic phase resetting) abolished cocaine-induced phase shifts at subjective midday. |
2012-05-15 |
2023-08-12 |
mouse |