| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Angela Chen, Lauren D S Kelley, Skirmantas Janušoni. Effects of prenatal stress and monoaminergic perturbations on the expression of serotonin 5-HT₄ and adrenergic β₂ receptors in the embryonic mouse telencephalon. Brain research. vol 1459. 2012-09-18. PMID:22564922. |
since 5-ht(4)rs are important in forebrain function (including forebrain control of serotonergic activity in the brainstem), we investigated the susceptibility of 5-ht(4)r expression in the mouse embryonic telencephalon to prenatal maternal stress and altered serotonin (5-hydroxytryptamine, 5-ht) levels. |
2012-09-18 |
2023-08-12 |
mouse |
| Kelly Conlon, Wes Miner, Scott McCleary, Gordon McMurra. Identification of 5-HT(2C) mediated mechanisms involved in urethral sphincter reflexes in a guinea-pig model of urethral function. BJU international. vol 110. issue 2 Pt 2. 2012-09-13. PMID:22192599. |
the in vivo data reported in the present study suggest that the effects of clinical agents used to treat stress urinary incontinence, which enhance serotonergic drive, may be mediated, at least in part, via 5-ht(2c) receptors. |
2012-09-13 |
2023-08-12 |
Not clear |
| F Duval, M C Mokrani, P Bailey, H Corrêa, M A Crocq, T Son Diep, J P Mache. Serotonergic and noradrenergic function in depression: clinical correlates. Dialogues in clinical neuroscience. vol 2. issue 3. 2012-09-10. PMID:22033550. |
the present study was conducted in order to investigate the relationships between central noradrenergic (na) and serotonergic (5-ht) function and clinical characteristics of a major depressive episode according to the diagnostic and statistical manual of mental disorders, fourth edition. |
2012-09-10 |
2023-08-12 |
Not clear |
| b' P Favr\\xc3\\xa. [Clinical efficacy and achievement of a complete remission in depression: increasing interest in treatment with escitalopram]. L\'Encephale. vol 38. issue 1. 2012-09-06. PMID:22381728.' |
these analyses are in favor of a superior efficacy and tolerability of long-term escitalopram treatment (10 to 20mg/day) compared with active controls, including selective serotonin re-uptake inhibitors (ssris) (paroxetine, citalopram, bupropion, fluoxetine, fluvoxamine, sertraline), serotonin/noradrenaline reuptake inhibitors (snris) (venlafaxine, milnacipran and duloxetine) and noradrenergic and specific serotonergic antidepressants (nassas) (mirtazapine). |
2012-09-06 |
2023-08-12 |
Not clear |
| Mark D Underwood, Suham A Kassir, Mihran J Bakalian, Hanga Galfalvy, J John Mann, Victoria Arang. Neuron density and serotonin receptor binding in prefrontal cortex in suicide. The international journal of neuropsychopharmacology. vol 15. issue 4. 2012-09-05. PMID:21733245. |
thus, abnormalities in both cortical neurons and in their serotonergic innervation are present in suicides and future studies will need to determine whether cortical changes reflect the trophic effect of altered serotonin innervation. |
2012-09-05 |
2023-08-12 |
Not clear |
| P Weeke, A Jensen, F Folke, G H Gislason, J B Olesen, C Andersson, E L Fosbøl, J K Larsen, F K Lippert, S L Nielsen, T Gerds, P K Andersen, J K Kanters, H E Poulsen, S Pehrson, L Køber, C Torp-Pederse. Antidepressant use and risk of out-of-hospital cardiac arrest: a nationwide case-time-control study. Clinical pharmacology and therapeutics. vol 92. issue 1. 2012-09-04. PMID:22588605. |
tricyclic antidepressants (tcas; odds ratio (or) = 1.69, confidence interval (ci): 1.14-2.50) and selective serotonin reuptake inhibitors (ssris; or = 1.21, ci: 1.00-1.47) were both associated with comparable increases in risk of ohca, whereas no association was found for serotonin-norepinephrine reuptake inhibitors/noradrenergic and specific serotonergic antidepressants (snris/nassas; or = 1.06, ci: 0.81-1.39). |
2012-09-04 |
2023-08-12 |
Not clear |
| Evandro Neves Abdo, Jeane de Fátima Correia-Silva, Carolina Cavaliéri Gomes, Isabela Almeida Pordeus, Ricardo Santiago Gome. Serotonin transporter gene polymorphisms: a case-control study. Brazilian dental journal. vol 23. issue 1. 2012-08-31. PMID:22460318. |
considerable evidence indicates that serotonergic mechanisms, particularly the serotonin transporter, are involved in alcoholism and tobacco use and are influenced by polymorphism of the promoter region of 5htt (5-httlpr). |
2012-08-31 |
2023-08-12 |
human |
| Dorothea Strobac. [Clinically significant drug-drug interactions between analgesics and psychotopics]. Medizinische Monatsschrift fur Pharmazeuten. vol 35. issue 7. 2012-08-28. PMID:22852275. |
under treatment with several serotonergic substances serotonin syndrome can occur, e.g., with certain opioids and antidepressant drugs. |
2012-08-28 |
2023-08-12 |
Not clear |
| Takeshi Shimada, Yoshihiro Takai, Kikuko Shinohara, Atsushi Yamasaki, Keiko Tominaga-Yoshino, Akihiko Ogura, Akihiro Toi, Kouji Asano, Norihito Shintani, Atsuko Hayata-Takano, Akemichi Baba, Hitoshi Hashimot. A simplified method to generate serotonergic neurons from mouse embryonic stem and induced pluripotent stem cells. Journal of neurochemistry. vol 122. issue 1. 2012-08-27. PMID:22404309. |
we found that noggin, a known antagonist of bone morphogenic protein, induces es cells to express genes involved in serotonergic differentiation, such as nkx2.2, pet-1, sonic hedgehog, tryptophan hydroxylase 2, and serotonin transporter, as well as increases high potassium-induced release of serotonin. |
2012-08-27 |
2023-08-12 |
mouse |
| Pnar Gelener, Umit Gorgulu, Gulnihal Kutlu, Serap Ucler, Levent Ertugrul Ina. Serotonin syndrome due to duloxetine. Clinical neuropharmacology. vol 34. issue 3. 2012-08-24. PMID:21586918. |
serotonin syndrome is a toxic condition due to serotoninergic hyperstimulation, which is caused mostly by serotonergic agents either in overdose or in combination. |
2012-08-24 |
2023-08-12 |
Not clear |
| Sarah K Williams, Jean M Lauder, Josephine M John. Prenatal Cocaine Disrupts Serotonin Signaling-Dependent Behaviors: Implications for Sex Differences, Early Stress and Prenatal SSRI Exposure. Current neuropharmacology. vol 9. issue 3. 2012-08-23. PMID:22379462. |
in order to understand the role of the serotonin transporter in cocaine's effect on the serotonergic system, we compare reports concerning pc and prenatal antidepressant exposure and conclude that pc exposure affects many facets of serotonergic signaling (serotonin levels, receptors, transporters) and that these effects differ significantly from what is observed following prenatal ssri exposure. |
2012-08-23 |
2023-08-12 |
Not clear |
| Kathryn M Buller, Julie A Wixey, Hanna E Reinebran. Disruption of the serotonergic system after neonatal hypoxia-ischemia in a rodent model. Neurology research international. vol 2012. 2012-08-23. PMID:22474587. |
one week after postnatal day 3 hypoxia-ischemia, losses of serotonergic raphé neurons, reductions in serotonin levels in the brain, and reduced serotonin transporter expression are evident. |
2012-08-23 |
2023-08-12 |
Not clear |
| Mandeep Singh, Thomas L Schwart. Clinical utility of vilazodone for the treatment of adults with major depressive disorder and theoretical implications for future clinical use. Neuropsychiatric disease and treatment. vol 8. 2012-08-23. PMID:22536068. |
this combined activity results in serotonin facilitation across the brain's serotonergic pathways, which has been termed by the authors as that of a serotonin partial agonist and reuptake inhibitor, or spari. |
2012-08-23 |
2023-08-12 |
Not clear |
| Hamood Ur-Rehman Malik, Krishan Kuma. Serotonin syndrome with escitolapram and concomitant use of cocaine: a case report. Clinical medicine insights. Case reports. vol 5. 2012-08-23. PMID:22719217. |
serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the central nervous system. |
2012-08-23 |
2023-08-12 |
Not clear |
| Hamood Ur-Rehman Malik, Krishan Kuma. Serotonin syndrome with escitolapram and concomitant use of cocaine: a case report. Clinical medicine insights. Case reports. vol 5. 2012-08-23. PMID:22719217. |
serotonin syndrome classically occurs in patients receiving two or more serotonergic drugs, but it can occur with monotherapy. |
2012-08-23 |
2023-08-12 |
Not clear |
| Qiao-Jun Zhang, Rui Gao, Jian Liu, Ya-Ping Liu, Shuang Wan. Changes in the firing activity of serotonergic neurons in the dorsal raphe nucleus in a rat model of Parkinson's disease. Sheng li xue bao : [Acta physiologica Sinica]. vol 59. issue 2. 2012-08-20. PMID:17437041. |
in the present study, changes in the neuronal activity of serotonergic neurons in the dorsal raphe nucleus (drn) and the effect of the selective 5-ht(1a) receptor antagonist way-100635 in a rat model of parkinson's disease (pd) were investigated by using extracellular single unit recording. |
2012-08-20 |
2023-08-12 |
rat |
| Havan Furmaga, Mohona Sadhu, Alan Fraze. Comparison of ΔFosB immunoreactivity induced by vagal nerve stimulation with that caused by pharmacologically diverse antidepressants. The Journal of pharmacology and experimental therapeutics. vol 341. issue 2. 2012-08-20. PMID:22286499. |
double-labeling of Δfosb and serotonin was used to determine whether serotonergic neurons in the dorsal raphe nucleus (drn) were activated by long-term vns. |
2012-08-20 |
2023-08-12 |
rat |
| Havan Furmaga, Mohona Sadhu, Alan Fraze. Comparison of ΔFosB immunoreactivity induced by vagal nerve stimulation with that caused by pharmacologically diverse antidepressants. The Journal of pharmacology and experimental therapeutics. vol 341. issue 2. 2012-08-20. PMID:22286499. |
double-labeling of the drn with Δfosb and an antibody for serotonin revealed that only a small percentage of Δfosb staining in the drn colocalized with serotonergic neurons. |
2012-08-20 |
2023-08-12 |
rat |
| Gláucia M Reis, A C Rossaneis, J W S Silveira, W A Prad. μ1- and 5-HT1-dependent mechanisms in the anterior pretectal nucleus mediate the antinociceptive effects of retrosplenial cortex stimulation in rats. Life sciences. vol 90. issue 23-24. 2012-08-16. PMID:22575824. |
this study examines if injection of cobalt chloride (cocl(2)) or antagonists of muscarinic cholinergic (atropine), μ(1)-opioid (naloxonazine) or 5-ht(1) serotonergic (methiothepin) receptors into the dorsal or ventral portions of the anterior pretectal nucleus (aptn) alters the antinociceptive effects of stimulating the retrosplenial cortex (rsc) in rats. |
2012-08-16 |
2023-08-12 |
rat |
| Galina T Shishkina, Tatyana S Kalinina, Inna V Berezova, Nikolay N Dygal. Stress-induced activation of the brainstem Bcl-xL gene expression in rats treated with fluoxetine: correlations with serotonin metabolism and depressive-like behavior. Neuropharmacology. vol 62. issue 1. 2012-08-13. PMID:21740920. |
mechanisms underlying stress-induced depression and antidepressant drug action were shown to involve alterations in serotonergic (5-ht) neurotransmission and expression of genes coding for proteins associated with neurotrophic signaling pathways and cell-survival in the hippocampus and cortex. |
2012-08-13 |
2023-08-12 |
rat |