| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Carl L Faingold, Marcus Randall, Yashanad Mhaskar, Victor V Uteshe. Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice. Brain research. vol 1418. 2012-01-30. PMID:21920504. |
this study examined the effects of a 5-ht(2b/2c) agonist (m-chlorophenylpiperazine, mcpp) to test the generality of serotonergic effects on dba mice. |
2012-01-30 |
2023-08-12 |
mouse |
| Koilmani Emmanuvel Rajan, Hemant K Singh, Arunagiri Parkavi, Prisila Dulcy Charle. Attenuation of 1-(m-chlorophenyl)-biguanide induced hippocampus-dependent memory impairment by a standardised extract of Bacopa monniera (BESEB CDRI-08). Neurochemical research. vol 36. issue 11. 2012-01-27. PMID:21735137. |
our results suggest that beseb cdri-08 possibly acts on serotonergic system, which in turn influences the cholinergic system through 5-ht(3) receptor to improve the hippocampal-dependent task. |
2012-01-27 |
2023-08-12 |
rat |
| Vanessa Nunes-de-Souza, Ricardo Nunes-de-Souza, Robert John Rodgers, Azair Canto-de-Souz. Blockade of 5-HT(2) receptors in the periaqueductal grey matter (PAG) abolishes the anxiolytic-like effect of 5-HT(1A) receptor antagonism in the median raphe nucleus in mice. Behavioural brain research. vol 225. issue 2. 2012-01-24. PMID:21839779. |
several lines of evidence support the involvement of serotonergic (5-ht) neurons of the median raphe nucleus (mrn) in anxiety-like behaviour. |
2012-01-24 |
2023-08-12 |
mouse |
| Jaime M Monti, Héctor Jantos, Valentina Catenaccio, Silvia Xavie. Blockade of the NMDA and AMPA/kainate receptors in the dorsal raphe nucleus prevents the 5-HT₃ receptor agonist m-chlorophenylbiguanide-induced suppression of REM sleep in the rat. Progress in neuro-psychopharmacology & biological psychiatry. vol 35. issue 5. 2012-01-19. PMID:21514352. |
it is proposed that the reduction of rems after microinjection of m-cpbg into de drn is related to the activation of glutamatergic interneurons that express the 5-ht(3) receptor and make synaptic contacts with serotonergic cells. |
2012-01-19 |
2023-08-12 |
rat |
| Marta Kot, Władysława A Danie. Cytochrome P450 is regulated by noradrenergic and serotonergic systems. Pharmacological research. vol 64. issue 4. 2012-01-19. PMID:21742037. |
rats were injected intraperitoneally with n-(2-chloroethyl)-n-ethyl-2-bromobenzylamine (dsp-4, a noradrenergic neurotoxin) or p-chloroamphetamine (pca, a serotonergic neurotoxin) or p-chlorophenylalanine (pcpa, an inhibitor of serotonin synthesis). |
2012-01-19 |
2023-08-12 |
rat |
| Kei Eto, Sun Kwang Kim, Junichi Nabekura, Hitoshi Ishibash. Taltirelin, a thyrotropin-releasing hormone analog, alleviates mechanical allodynia through activation of descending monoaminergic neurons in persistent inflammatory pain. Brain research. vol 1414. 2012-01-18. PMID:21872219. |
these findings suggest that taltirelin alleviates mechanical allodynia in inflammatory persistent pain by modulating the descending noradrenergic and serotonergic neuronal pathways via indirect activation of spinal α₂-adrenergic and 5-ht(1a) receptors. |
2012-01-18 |
2023-08-12 |
mouse |
| Federico Rodriguez-Porcel, Donald Green, Nidhi Khatri, Sharonda Swilley Harris, Warren L May, Rick C S Lin, Ian A Pau. Neonatal exposure of rats to antidepressants affects behavioral reactions to novelty and social interactions in a manner analogous to autistic spectrum disorders. Anatomical record (Hoboken, N.J. : 2007). vol 294. issue 10. 2012-01-17. PMID:21905242. |
we have demonstrated that neonatal exposure to selective serotonin reuptake inhibitors has lasting effects on behavior and serotonergic neurons in long evans rats. |
2012-01-17 |
2023-08-12 |
rat |
| Mai Lan Leong, Ming Gu, Rebecca Speltz-Paiz, Eleanor I Stahura, Neli Mottey, Clifford J Steer, Martin Wessendor. Neuronal loss in the rostral ventromedial medulla in a rat model of neuropathic pain. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 47. 2012-01-16. PMID:22114272. |
among rvm neurons, we found that serotonergic (5-hydroxytryptamine, 5-ht) neurons decreased by 35% ipsilateral to snl. |
2012-01-16 |
2023-08-12 |
rat |
| Suhreta Mujakovic, José Jm ter Linde, Niek J de Wit, Corine J van Marrewijk, Gerdine Aj Fransen, N Charlotte Onland-Moret, Robert Jf Laheij, Jean Wm Muris, Diederick E Grobbee, Melvin Samsom, Jan Bmj Jansen, André Knottnerus, Mattijs E Numan. Serotonin receptor 3A polymorphism c.-42C > T is associated with severe dyspepsia. BMC medical genetics. vol 12. 2012-01-06. PMID:22014438. |
a functional polymorphism in the serotonin transporter (5-htt), which terminates serotonergic signalling, was also found associated with these psychiatric comorbidities and increased visceral sensitivity in irritable bowel syndrome, which coexistence is associated with higher dyspeptic symptom severity. |
2012-01-06 |
2023-08-12 |
Not clear |
| L M Hurley, I C Hal. Context-dependent modulation of auditory processing by serotonin. Hearing research. vol 279. issue 1-2. 2012-01-05. PMID:21187135. |
although the release of serotonin is likely to be relatively diffuse, highly specific effects of serotonin on auditory neural circuitry are achieved through the localization of serotonergic projections, and through a large array of receptor types that are expressed by specific subsets of auditory neurons. |
2012-01-05 |
2023-08-12 |
Not clear |
| Daniel Eskenazi, John F Neumaie. Increased expression of 5-HT₆ receptors in dorsolateral striatum decreases habitual lever pressing, but does not affect learning acquisition of simple operant tasks in rats. The European journal of neuroscience. vol 34. issue 2. 2012-01-05. PMID:21714816. |
medications acting on the serotonergic system, including 5-ht(6) receptors, can diminish habitual and repetitive behaviors associated with clinical syndromes such as obsessive-compulsive disorder, and may have implications for addiction as well. |
2012-01-05 |
2023-08-12 |
rat |
| Enrique Jiménez-Ferrer, Maribel Herrera-Ruiz, Raúl Ramírez-García, Armando Herrera-Arellano, Jaime Tortoriell. Interaction of the natural anxiolytic Galphimine-B with serotonergic drugs on dorsal hippocampus in rats. Journal of ethnopharmacology. vol 137. issue 1. 2011-12-27. PMID:21742023. |
for this reason, the objective of this work was to evaluate the pharmacological interaction between g-b with the 5-hydroxytryptamine 1a (5ht(1a)) and 5-hydroxytryptamine 2a (5ht(2a)) serotonergic receptors on ca1 neurons of hippocampus. |
2011-12-27 |
2023-08-12 |
rat |
| Margaret Hahn, Araba Chintoh, Adria Giacca, Li Xu, Loretta Lam, Steve Mann, Paul Fletcher, Melanie Guenette, Tony Cohn, Tom Wolever, Tamara Arenovich, Gary Remingto. Atypical antipsychotics and effects of muscarinic, serotonergic, dopaminergic and histaminergic receptor binding on insulin secretion in vivo: an animal model. Schizophrenia research. vol 131. issue 1-3. 2011-12-23. PMID:21696923. |
results suggest that the effects of antipsychotics on glucose dysregulation may be related to direct inhibitory effects of muscarinic (m(3)) and serotonergic (5ht(2)) antagonism on insulin secretion. |
2011-12-23 |
2023-08-12 |
rat |
| Wendy R Zeng, Stewart R A Fabb, John M Haynes, Colin W Pouto. Extended periods of neural induction and propagation of embryonic stem cell-derived neural progenitors with EGF and FGF2 enhances Lmx1a expression and neurogenic potential. Neurochemistry international. vol 59. issue 3. 2011-12-19. PMID:21624410. |
4 and 7-day ns cell cultures could not be differentiated towards dopaminergic, serotonergic or cholinergic fates as determined by the absence of tyrosine hydroxylase, 5-ht or choline acetyltransferase (chat) immunolabelling. |
2011-12-19 |
2023-08-12 |
mouse |
| Glauber S F da Silva, Humberto Giusti, Maurício Benedetti, Mirela B Dias, Luciane H Gargaglioni, Luiz Guilherme S Branco, Mogens L Glas. Serotonergic neurons in the nucleus raphe obscurus contribute to interaction between central and peripheral ventilatory responses to hypercapnia. Pflugers Archiv : European journal of physiology. vol 462. issue 3. 2011-12-19. PMID:21739157. |
serotonergic (5-ht) neurons in the nucleus raphe obscurus (rob) are involved in the respiratory control network. |
2011-12-19 |
2023-08-12 |
rat |
| Christina Herold, Nicola Palomero-Gallagher, Burkhard Hellmann, Sven Kröner, Carsten Theiss, Onur Güntürkün, Karl Zille. The receptor architecture of the pigeons' nidopallium caudolaterale: an avian analogue to the mammalian prefrontal cortex. Brain structure & function. vol 216. issue 3. 2011-12-12. PMID:21293877. |
here we analyzed binding-site densities of glutamatergic ampa, nmda and kainate receptors, gabaergic gaba(a), muscarinic m(1), m(2) and nicotinic (nach) receptors, noradrenergic α(1) and α(2), serotonergic 5-ht(1a) and dopaminergic d(1)-like receptors using quantitative in vitro receptor autoradiography. |
2011-12-12 |
2023-08-12 |
human |
| Nissar A Darmani, Seetha Chebolu, Barry Amos, Tursun Alka. Synergistic antiemetic interactions between serotonergic 5-HT3 and tachykininergic NK1-receptor antagonists in the least shrew (Cryptotis parva). Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21683089. |
significant electrophysiological and biochemical findings suggest that receptor cross-talk occurs between serotonergic 5-ht(3)- and tachykininergic nk(1)-receptors in which co-activation of either receptor by ineffective doses of their corresponding agonists (serotonin (5-ht) or substance p (sp), respectively) potentiates the activity of the other receptor to produce a response. |
2011-12-09 |
2023-08-12 |
Not clear |
| Su-Ying Cui, Xiang-Yu Cui, Juan Zhang, Zi-Jun Wang, Bin Yu, Zhao-Fu Sheng, Xue-Qiong Zhang, Xiao-Lei Shi, Yong-He Zhan. Diltiazem potentiates pentobarbital-induced hypnosis via 5-HT1A and 5-HT2A/2C receptors: role for dorsal raphe nucleus. Pharmacology, biochemistry, and behavior. vol 99. issue 4. 2011-12-09. PMID:21689675. |
this study was designed to investigate the role of drn and the serotonergic receptors 5-ht(1a) and 5-ht(2a/2c) in the augmentative effect of diltiazem on pentobarbital-induced hypnosis in rats. |
2011-12-09 |
2023-08-12 |
rat |
| Gareth Harris, Amanda Korchnak, Philip Summers, Vera Hapiak, Wen Jing Law, Andrew M Stein, Patricia Komuniecki, Richard Komunieck. Dissecting the serotonergic food signal stimulating sensory-mediated aversive behavior in C. elegans. PloS one. vol 6. issue 7. 2011-12-08. PMID:21814562. |
nsm 5-ht activates ser-5 on the ashs and ser-1 on the ria interneurons and stimulates aversive responses, suggesting that food-dependent serotonergic stimulation involves local changes in 5-ht levels mediated by extrasynaptic 5-ht receptors. |
2011-12-08 |
2023-08-12 |
caenorhabditis_elegans |
| Tamara B Franklin, Natacha Linder, Holger Russig, Beat Thöny, Isabelle M Mansu. Influence of early stress on social abilities and serotonergic functions across generations in mice. PloS one. vol 6. issue 7. 2011-12-06. PMID:21799751. |
the defects are associated with impaired serotonergic signaling, in particular, reduced 5ht1a receptor expression in the dorsal raphe nucleus, and increased serotonin level in a dorsal raphe projection area. |
2011-12-06 |
2023-08-12 |
mouse |