| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Cecilia Aslund, Erika Comasco, Niklas Nordquist, Jerzy Leppert, Lars Oreland, Kent W Nilsso. Self-reported family socioeconomic status, the 5-HTTLPR genotype, and delinquent behavior in a community-based adolescent population. Aggressive behavior. vol 39. issue 1. 2013-07-12. PMID:22987641. |
associations have been reported between the serotonin transporter (5-htt) and aggression, and between socioeconomic status (ses), aggression, and serotonergic functions of the brain. |
2013-07-12 |
2023-08-12 |
Not clear |
| A Ferrés-Coy, F Pilar-Cuellar, R Vidal, V Paz, M Masana, R Cortés, M C Carmona, L Campa, A Pazos, A Montefeltro, E M Valdizán, F Artigas, A Bortolozz. RNAi-mediated serotonin transporter suppression rapidly increases serotonergic neurotransmission and hippocampal neurogenesis. Translational psychiatry. vol 3. 2013-07-04. PMID:23321808. |
rnai-mediated serotonin transporter suppression rapidly increases serotonergic neurotransmission and hippocampal neurogenesis. |
2013-07-04 |
2023-08-12 |
mouse |
| R H Foster, K L Go. Paroxetine : a review of its pharmacology and therapeutic potential in the management of panic disorder. CNS drugs. vol 8. issue 2. 2013-07-04. PMID:23338224. |
it is a highly selective inhibitor of presynaptic serotonin reuptake and does not interact with adrenergic, dopaminergic, histaminergic or serotonergic receptors to any significant extent. |
2013-07-04 |
2023-08-12 |
Not clear |
| b' Pascal Amireault, David Sibon, Francine C\\xc3\\xb4t\\xc3\\xa. Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336045.' |
life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks. |
2013-07-02 |
2023-08-12 |
mouse |
| b' Pascal Amireault, David Sibon, Francine C\\xc3\\xb4t\\xc3\\xa. Life without peripheral serotonin: insights from tryptophan hydroxylase 1 knockout mice reveal the existence of paracrine/autocrine serotonergic networks. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336045.' |
within an organ, both the presence of local tph enzymatic activity and serotonergic components are of particular importance as they support the view that 5-ht meets the criteria to be qualified as a monoamine with a paracrine/autocrine function. |
2013-07-02 |
2023-08-12 |
mouse |
| William B Siesser, Benjamin D Sachs, Amy J Ramsey, Tatyana D Sotnikova, Jean-Martin Beaulieu, Xiaodong Zhang, Marc G Caron, Raul R Gainetdino. Chronic SSRI treatment exacerbates serotonin deficiency in humanized Tph2 mutant mice. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336047. |
both reuptake and ongoing synthesis are essential in supporting intraneuronal serotonin concentrations in serotonergic neurons. |
2013-07-02 |
2023-08-12 |
mouse |
| Stefanie C Altieri, Alvaro L Garcia-Garcia, E David Leonardo, Anne M Andrew. Rethinking 5-HT1A receptors: emerging modes of inhibitory feedback of relevance to emotion-related behavior. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336046. |
new concepts as to how 5-ht(1a) receptors function to control serotonergic tone throughout life were highlights of the proceedings of the 2012 serotonin club meeting in montpellier, france. |
2013-07-02 |
2023-08-12 |
Not clear |
| Maarten van den Buus. Exploring the role of 5-HT1A receptors in the regulation of prepulse inhibition in mice: implications for cross-species comparisons. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336054. |
pretreatment with the serotonin precursor, 5-htp, to increase serotonergic activity in the brain, unmasked a decrease in ppi caused by 8-oh-dpat in c57bl/6 mice. |
2013-07-02 |
2023-08-12 |
mouse |
| Maarten van den Buus. Exploring the role of 5-HT1A receptors in the regulation of prepulse inhibition in mice: implications for cross-species comparisons. ACS chemical neuroscience. vol 4. issue 1. 2013-07-02. PMID:23336054. |
pretreatment with the serotonin synthesis inhibitor, pcpa, to decrease serotonergic activity in the brain, unmasked an 8-oh-dpat-induced increase in ppi in this strain. |
2013-07-02 |
2023-08-12 |
mouse |
| Hwa-Young Lee, Chae Keun Oh, Byung-Joo Ham, Hun Soo Chang, Jong-Woo Paik, Eun-Soo Won, Sang-Woo Hahn, Se-Hoon Shim, Young-Joon Kwon, Hee-Yeon Jung, Min-Soo Le. No Association between Serotonin Receptor 2C-759C/T Polymorphism and Weight Change or Treatment Response to Mirtazapine in Korean Depressive Patients. Psychiatry investigation. vol 10. issue 2. 2013-06-27. PMID:23798968. |
activation of one or more serotonin (5-ht) receptors may play a role in mediating the antidepressant effects of serotonergic antidepressants. |
2013-06-27 |
2023-08-12 |
Not clear |
| Tania Vitalis, Mark S Ansorge, Alexandre G Daye. Serotonin homeostasis and serotonin receptors as actors of cortical construction: special attention to the 5-HT3A and 5-HT6 receptor subtypes. Frontiers in cellular neuroscience. vol 7. 2013-06-27. PMID:23801939. |
5-ht is detected at the onset of embryonic telencephalic formation and a variety of serotonergic receptors are dynamically expressed in the embryonic developing cortex in a region and cell-type specific manner. |
2013-06-27 |
2023-08-12 |
human |
| P Baldinger, G Kranz, A Höflich, M Savli, P Stein, R Lanzenberger, S Kaspe. [The effects of hormone replacement therapy on mind and brain]. Der Nervenarzt. vol 84. issue 1. 2013-06-26. PMID:22318360. |
the important role of the neurotransmitter serotonin in the pathogenesis of anxiety disorders and major depression is unquestioned, but only little is known about the influence of sex hormones on the serotonergic system. |
2013-06-26 |
2023-08-12 |
Not clear |
| Lei Xu, Hua Tian, Wei Wang, Shaoguo R. Effects of monocrotophos pesticide on serotonin metabolism during early development in the sea urchin, Hemicentrotus pulcherrimus. Environmental toxicology and pharmacology. vol 34. issue 2. 2013-06-25. PMID:22824501. |
to investigate the mechanism by which monocrotophos (mcp) pesticide disrupts the serotonergic nervous system, we evaluated its effects on serotonin metabolism. |
2013-06-25 |
2023-08-12 |
Not clear |
| Lei Xu, Hua Tian, Wei Wang, Shaoguo R. Effects of monocrotophos pesticide on serotonin metabolism during early development in the sea urchin, Hemicentrotus pulcherrimus. Environmental toxicology and pharmacology. vol 34. issue 2. 2013-06-25. PMID:22824501. |
when serotonin should be quickly metabolized at 36-hpf stage, hptph and sert expression was decreased and mao activity was induced by mcp pesticide, leading to the impairment of serotonergic synaptic activity. |
2013-06-25 |
2023-08-12 |
Not clear |
| Lei Xu, Hua Tian, Wei Wang, Shaoguo R. Effects of monocrotophos pesticide on serotonin metabolism during early development in the sea urchin, Hemicentrotus pulcherrimus. Environmental toxicology and pharmacology. vol 34. issue 2. 2013-06-25. PMID:22824501. |
but when serotonin should be metabolized at low levels during the other six stages, mcp pesticide induced hptph and sert expression, resulting in the improvement of serotonergic synaptic activity. |
2013-06-25 |
2023-08-12 |
Not clear |
| Francesc Artiga. Serotonin receptors involved in antidepressant effects. Pharmacology & therapeutics. vol 137. issue 1. 2013-06-20. PMID:23022360. |
presynaptic 5-ht(1a) and 5-ht(1b) autoreceptors play a major detrimental role in antidepressant treatments, as their activation by the excess of the active (extracellular) 5-ht fraction produced by serotonin transporter (sert) blockade reduces presynaptic serotonergic function. |
2013-06-20 |
2023-08-12 |
Not clear |
| Francesc Artiga. Serotonin receptors involved in antidepressant effects. Pharmacology & therapeutics. vol 137. issue 1. 2013-06-20. PMID:23022360. |
the 5-ht(2) receptor family is also involved as 5-ht(2a/2c) receptor blockade improves the antidepressant action of ssris, and recent data suggest that 5-ht(2b) receptor activation enhances serotonergic activity. |
2013-06-20 |
2023-08-12 |
Not clear |
| Karsten Kinast, Deborah Peeters, Sharon M Kolk, Dirk Schubert, Judith R Homber. Genetic and pharmacological manipulations of the serotonergic system in early life: neurodevelopmental underpinnings of autism-related behavior. Frontiers in cellular neuroscience. vol 7. 2013-06-20. PMID:23781172. |
the serotonergic system is one of the earliest to develop during embryogenesis and early changes in serotonin levels can have large consequences for the correct development of specific brain areas. |
2013-06-20 |
2023-08-12 |
human |
| Karsten Kinast, Deborah Peeters, Sharon M Kolk, Dirk Schubert, Judith R Homber. Genetic and pharmacological manipulations of the serotonergic system in early life: neurodevelopmental underpinnings of autism-related behavior. Frontiers in cellular neuroscience. vol 7. 2013-06-20. PMID:23781172. |
furthermore, prenatal valproic acid (vpa) exposure, a mood stabilizing drug which is also thought to interfere with serotonin levels, has the potency to induce asd-like symptoms and to affect the development of the serotonergic system. |
2013-06-20 |
2023-08-12 |
human |
| Wan-Hui Lin, Hua-Pin Huang, Ming-Xing Lin, Sheng-Gen Chen, Xiao-Chai Lv, Chun-Hui Che, Ji-Lan Li. Seizure-induced 5-HT release and chronic impairment of serotonergic function in rats. Neuroscience letters. vol 534. 2013-06-18. PMID:23276638. |
seizure-induced 5-ht release and chronic impairment of serotonergic function in rats. |
2013-06-18 |
2023-08-12 |
rat |