| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Esther Asan, Maria Steinke, Klaus-Peter Lesc. Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety. Histochemistry and cell biology. vol 139. issue 6. 2013-12-03. PMID:23494464. |
here, we present a short overview over organizational principles of the amygdala in rodents, non-human primates and humans, and review findings on the origin, morphology, and targets of serotonergic innervation, the distribution patterns and cellular expression of serotonin receptors, and the consequences of stress and pharmacological manipulations of serotonergic transmission in the amygdala, focusing particularly on the extensively studied basolateral complex and central nucleus. |
2013-12-03 |
2023-08-12 |
human |
| D De Berardis, C M Conti, S Marini, F Ferri, F Iasevoli, A Valchera, M Fornaro, M Cavuto, V Srinivasan, G Perna, A Carano, M Piersanti, G Martinotti, M Di Giannantoni. Is there a role for agomelatine in the treatment of anxiety disorders?A review of published data. International journal of immunopathology and pharmacology. vol 26. issue 2. 2013-12-03. PMID:23755745. |
anxiety disorders (ads) are the most common type of psychiatric disorders, pharmacologic options studied for treating ads may include benzodiazepines, tricyclic antidepressants (tca), selective serotonin reuptake inhibitors (ssris), noradrenergic and specific serotonergic antidepressants (nassa) and serotonin and noradrenaline reuptake inhibitors (snris). |
2013-12-03 |
2023-08-12 |
Not clear |
| Stuart I Hodgetts, Paul J Simmons, Giles W Plan. A comparison of the behavioral and anatomical outcomes in sub-acute and chronic spinal cord injury models following treatment with human mesenchymal precursor cell transplantation and recombinant decorin. Experimental neurology. vol 248. 2013-11-27. PMID:23867131. |
hmpc transplanted spinal cords showed the increased presence of serotonergic (5-ht) and sensory (cgrp) axonal growth within and surrounding transplanted hmpcs for up to 2 months; however, no evidence of hmpc transdifferentiation into neuronal or glial phenotypes. |
2013-11-27 |
2023-08-12 |
human |
| Hsiao-Hsien Kang, Chih-Hung Wang, Hsin-Chien Chen, I-Hsun Li, Cheng-Yi Cheng, Ren-Shyan Liu, Wen-Sheng Huang, Chyng-Yann Shiue, Kuo-Hsing M. Investigating the effects of noise-induced hearing loss on serotonin transporters in rat brain using 4-[18F]-ADAM/small animal PET. NeuroImage. vol 75. 2013-11-26. PMID:22766166. |
the serotonin transporter (sert) is an important marker of the status of serotonergic neurons. |
2013-11-26 |
2023-08-12 |
rat |
| Jorge Emilio Ortega, Victor Gonzalez-Lira, Igor Horrillo, Mario Herrera-Marschitz, Luis Felipe Callado, J Javier Mean. Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain. European journal of pharmacology. vol 709. issue 1-3. 2013-11-26. PMID:23562616. |
for this purpose extracellular 5-ht levels were monitored with microdialysis in forebrain (prefrontal cortex, pfc) and mesencephalic (locus coeruleus, lc) serotonergic terminal areas in freely awake rats. |
2013-11-26 |
2023-08-12 |
rat |
| Jorge Emilio Ortega, Victor Gonzalez-Lira, Igor Horrillo, Mario Herrera-Marschitz, Luis Felipe Callado, J Javier Mean. Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain. European journal of pharmacology. vol 709. issue 1-3. 2013-11-26. PMID:23562616. |
the present results demonstrate that the cannabinoid cb1 receptor antagonist rimonabant is able to enhance in an additive manner the citalopram-induced increase of 5-ht concentrations in serotonergic terminal areas. |
2013-11-26 |
2023-08-12 |
rat |
| Mathieu Seimandi, Pascal Seyer, C Sehwan Park, Franck Vandermoere, Benjamin Chanrion, Joël Bockaert, Isabelle M Mansuy, Philippe Mari. Calcineurin interacts with the serotonin transporter C-terminus to modulate its plasma membrane expression and serotonin uptake. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 41. 2013-11-26. PMID:24107951. |
homeostasis of serotonergic transmission critically depends on the rate of serotonin reuptake via its plasma membrane transporter (sert). |
2013-11-26 |
2023-08-12 |
mouse |
| S K Bhattacharya, S S Parma. Prostaglandin d2 induced potentiation of the anticonvulsant actions of phenobarbitone and phenytoin in rats. Role of serotonin. Pharmaceutical research. vol 2. issue 6. 2013-11-26. PMID:24271132. |
pdg2-induced potentiation of phenobarbitone and phenytoin was significantly attenuated following pretreatment with centrally administered 5,6-dihydroxytryptamine, a selective neurotoxin for serotonergic neurones, p-chlorophenylalanine, a specific inhibitor of serotonin biosynthesis, and methysergide, a serotonin receptor antagonist, indicating that the potentiation was serotonin-mediated. |
2013-11-26 |
2023-08-12 |
rat |
| S K Bhattacharya, N Da. Central Serotonergic Modulation of Carrageenin-induced Pedal Inflammation in Rats. Pharmaceutical research. vol 2. issue 6. 2013-11-26. PMID:24271133. |
quipazine, which inhibits neuronal release of serotonin, 5,6-dihydroxytryptamine (dht), a specific serotonergic neurotoxin, and p-chlorphenylalanine, a selective serotonin synthesis inhibitor, augmented carrageenin inflammation upon icv administration. |
2013-11-26 |
2023-08-12 |
rat |
| Sophie da Cunha-Bang, Dea Siggaard Stenbæk, Klaus Holst, Cecilie Löe Licht, Peter Steen Jensen, Vibe Gedsø Frokjaer, Erik Lykke Mortensen, Gitte Moos Knudse. Trait aggression and trait impulsivity are not related to frontal cortex 5-HT2A receptor binding in healthy individuals. Psychiatry research. vol 212. issue 2. 2013-11-19. PMID:23137806. |
numerous studies indicate that the serotonergic (5-ht) transmitter system is involved in the regulation of impulsive aggression and there is from post-mortem, in vivo imaging and genetic studies evidence that the 5-ht2a receptor may be involved. |
2013-11-19 |
2023-08-12 |
Not clear |
| Sara Fidalgo, Dobril K Ivanov, Shona H Woo. Serotonin: from top to bottom. Biogerontology. vol 14. issue 1. 2013-11-13. PMID:23100172. |
a decline in serotonin function with aging would be consistent with observations of age-related changes in behaviours, such as sleep, sexual behaviour and mood all of which are linked to serotonergic function. |
2013-11-13 |
2023-08-12 |
Not clear |
| Sara Fidalgo, Dobril K Ivanov, Shona H Woo. Serotonin: from top to bottom. Biogerontology. vol 14. issue 1. 2013-11-13. PMID:23100172. |
the regulation of serotonin via micrornas is also discussed, as are possible applications of serotonergic drugs in aging research and age-related diseases. |
2013-11-13 |
2023-08-12 |
Not clear |
| B Senthilkumaran, K P Jo. Effects of melatonin, p-chlorophenylalanine, and α-methylparatyrosine on plasma gonadotropin level and ovarian activity in the catfish, Heteropneustes fossilis: A study correlating changes in hypothalamic monoamines. Fish physiology and biochemistry. vol 14. issue 6. 2013-11-08. PMID:24197643. |
these results suggest that 5-ht, na and a are stimulatory to gth secretion and that melatonin may act on the serotonergic system to inhibit the pituitary-gonadal axis. |
2013-11-08 |
2023-08-12 |
Not clear |
| Van A Ortega, David A Lovejoy, Nicholas J Bernie. Appetite-suppressing effects and interactions of centrally administered corticotropin-releasing factor, urotensin I and serotonin in rainbow trout (Oncorhynchus mykiss). Frontiers in neuroscience. vol 7. 2013-11-06. PMID:24194695. |
therefore, the objectives of this study were to (1) assess the individual effects of synthesized rainbow trout crf (rtcrf), rtui as well as 5-ht on food intake in rainbow trout, and (2) determine whether the crf and serotonergic systems interact in the regulation of food intake in this species. |
2013-11-06 |
2023-08-12 |
Not clear |
| Van A Ortega, David A Lovejoy, Nicholas J Bernie. Appetite-suppressing effects and interactions of centrally administered corticotropin-releasing factor, urotensin I and serotonin in rainbow trout (Oncorhynchus mykiss). Frontiers in neuroscience. vol 7. 2013-11-06. PMID:24194695. |
icv injections of 5-ht also inhibited feeding in a dose-related manner (ed50 = 14.7 ng/g bw) and these effects were blocked by the serotonergic receptor antagonist methysergide. |
2013-11-06 |
2023-08-12 |
Not clear |
| Peter Weinberg, Nuria Flames, Hitoshi Sawa, Gian Garriga, Oliver Hober. The SWI/SNF chromatin remodeling complex selectively affects multiple aspects of serotonergic neuron differentiation. Genetics. vol 194. issue 1. 2013-11-05. PMID:23457234. |
we show that the effect of ham-3 on serotonergic fate can be explained by ham-3 regulating the expression of the spalt/sall-type zn finger transcription factor sem-4, a previously identified regulator of serotonin expression in hsns and of the ham-2 zn transcription factor, a previously identified regulator of hsn migration and axon outgrowth. |
2013-11-05 |
2023-08-12 |
human |
| L Speranza, A Chambery, M Di Domenico, M Crispino, V Severino, F Volpicelli, M Leopoldo, G C Bellenchi, U di Porzio, C Perrone-Capan. The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathways. Neuropharmacology. vol 67. 2013-11-04. PMID:23164613. |
serotonergic neurotransmission is mediated by at least 14 subtypes of 5-ht receptors. |
2013-11-04 |
2023-08-12 |
Not clear |
| Atieh Hajirahimkhan, Birgit M Dietz, Judy L Bolto. Botanical modulation of menopausal symptoms: mechanisms of action? Planta medica. vol 79. issue 7. 2013-11-01. PMID:23408273. |
black cohosh, kudzu, kava, licorice, and dong quai all either have reported 5-hydroxytryptamine receptor 7 ligands or inhibit serotonin reuptake, therefore have potential serotonergic activities. |
2013-11-01 |
2023-08-12 |
Not clear |
| Pablo R Moya, Jens R Wendland, Jennifer Salemme, Ruby L Fried, Dennis L Murph. miR-15a and miR-16 regulate serotonin transporter expression in human placental and rat brain raphe cells. The international journal of neuropsychopharmacology. vol 16. issue 3. 2013-10-31. PMID:22564678. |
the serotonin transporter (sert) is a key regulatory molecule in serotonergic transmission implicated in numerous biological processes relevant to human disorders. |
2013-10-31 |
2023-08-12 |
mouse |
| Naozumi Araragi, Klaus-Peter Lesc. Serotonin (5-HT) in the regulation of depression-related emotionality: insight from 5-HT transporter and tryptophan hydroxylase-2 knockout mouse models. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23547810. |
moreover, the recent advent of knockout (ko) mice for tryptophan hydroxylase 2 (tph2 ko), which lacks the rate-limiting enzyme for 5-ht synthesis in the brain, has further provided insight to the brain serotonergic system and its role in emotion dysregulation. |
2013-10-29 |
2023-08-12 |
mouse |