| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hanna S Lindgren, Merve Demirbugen, Filip Bergqvist, Emma L Lane, Stephen B Dunnet. The effect of additional noradrenergic and serotonergic depletion on a lateralised choice reaction time task in rats with nigral 6-OHDA lesions. Experimental neurology. vol 253. 2014-04-07. PMID:24333808. |
however, studies have demonstrated that this type of lesion also affects the serotonergic (5ht) and noradrenergic (na) systems. |
2014-04-07 |
2023-08-12 |
rat |
| Raffaella Calati, Florence Gressier, Martina Balestri, Alessandro Serrett. Genetic modulation of borderline personality disorder: systematic review and meta-analysis. Journal of psychiatric research. vol 47. issue 10. 2014-04-04. PMID:23810197. |
meta-analyses were performed for three serotonergic polymorphisms: two common polymorphisms of the serotonin transporter gene (slc6a4), the promoter insertion/deletion (5-httlpr) and the intron 2 vntr (stin2 vntr), and the rs1800532 (a218c) polymorphism of the tryptophan hydroxylase 1 gene (tph1), all showing no association. |
2014-04-04 |
2023-08-12 |
Not clear |
| Hiroki Shikanai, Shinichi Kimura, Hiroko Togash. Early life stress affects the serotonergic system underlying emotional regulation. Biological & pharmaceutical bulletin. vol 36. issue 9. 2014-04-01. PMID:23995647. |
an aversive stimulus, foot shock (fs), during the early postnatal period (2-3 weeks after birth) produced behavioral, neuroanatomical and electrophysiological changes accompanied by serotonergic dysfunction, especially functional impairment of the serotonin (5-hydroxytryptamine; 5-ht)1a receptor in the cortico-limbic area. |
2014-04-01 |
2023-08-12 |
rat |
| Begoña Fernández-Pastor, Jorge E Ortega, J Javier Mean. Involvement of serotonin 5-HT3 receptors in the modulation of noradrenergic transmission by serotonin reuptake inhibitors: a microdialysis study in rat brain. Psychopharmacology. vol 229. issue 2. 2014-03-31. PMID:23636303. |
selective serotonin reuptake inhibitors (ssris), in addition to being able to enhance serotonergic neurotransmission, are able to modulate other brain systems involved in depression. |
2014-03-31 |
2023-08-12 |
rat |
| Jennifer M Spaethling, David Piel, Hannah Dueck, Peter T Buckley, Jacqueline F Morris, Stephen A Fisher, Jaehee Lee, Jai-Yoon Sul, Junhyong Kim, Tamas Bartfai, Sheryl G Beck, James H Eberwin. Serotonergic neuron regulation informed by in vivo single-cell transcriptomics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 28. issue 2. 2014-03-27. PMID:24192459. |
despite the recognized importance of the dorsal raphe (dr) serotonergic (5-ht) nuclei in the pathophysiology of depression and anxiety, the molecular components/putative drug targets expressed by these neurons are poorly characterized. |
2014-03-27 |
2023-08-12 |
Not clear |
| Natsuko Tsujino, Tomomi Tsunematsu, Motokazu Uchigashima, Kohtarou Konno, Akihiro Yamanaka, Kazuto Kobayashi, Masahiko Watanabe, Yoshimasa Koyama, Takeshi Sakura. Chronic alterations in monoaminergic cells in the locus coeruleus in orexin neuron-ablated narcoleptic mice. PloS one. vol 8. issue 7. 2014-03-25. PMID:23922890. |
to evaluate this hypothesis, we examined firing patterns of serotonergic (5-ht) neurons and noradrenergic (na) neurons in the brain stem, two important neuronal populations in the regulation of sleep/wakefulness states. |
2014-03-25 |
2023-08-12 |
mouse |
| Xiu-Yu Shi, Li-Ping Zou, Guang Yang, Ying-Xue Ding, Bing He, Yan-Hong Sun, Fei-Yong Ji. Association of serotonin transporter polymorphisms with responsiveness to adrenocorticotropic hormone in infantile spasm. World journal of pediatrics : WJP. vol 9. issue 3. 2014-03-24. PMID:23775678. |
the serotonin transporter (5-htt) is a key regulator of the level of serotonergic neurotransmission. |
2014-03-24 |
2023-08-12 |
Not clear |
| R Vidal, A Diaz, A Pazos, E Castr. Region-specific regulation of 5-HT1B receptors in the rat brain by chronic venlafaxine treatment. Psychopharmacology. vol 229. issue 1. 2014-03-21. PMID:23609771. |
5-ht(1b) receptors are located in the axon terminals of both serotonergic and non-serotonergic neurons, where they act as inhibitory autoreceptors or heteroreceptors, respectively. |
2014-03-21 |
2023-08-12 |
rat |
| R L Dennis, D C Lay, H W Chen. Effects of early serotonin programming on behavior and central monoamine concentrations in an avian model. Behavioural brain research. vol 253. 2014-03-18. PMID:23912030. |
early agonism of 5-ht receptors could alter the development of serotonergic circuitry, altering neurotransmission and behaviors mediated by 5-ht signaling, including memory, fear and aggression. |
2014-03-18 |
2023-08-12 |
Not clear |
| Tim Hahn, Sebastian Heinzel, Karolien Notebaert, Thomas Dresler, Andreas Reif, Klaus-Peter Lesch, Peter M Jakob, Sabine Windmann, Andreas J Fallgatte. The tricks of the trait: neural implementation of personality varies with genotype-dependent serotonin levels. NeuroImage. vol 81. 2014-03-17. PMID:23684859. |
we provide evidence suggesting that genotype-dependent serotonin levels and thus putative changes in the efficiency of serotonergic neurotransmission might not only alter brain activation levels directly, but also more fundamentally impact the neural implementation of personality traits. |
2014-03-17 |
2023-08-12 |
human |
| Nidhi Kaushal, Michael J Seminerio, Matthew J Robson, Christopher R McCurdy, Rae R Matsumot. Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 8. 2014-03-13. PMID:22921523. |
sn79 pretreatment afforded protection against methamphetamine-induced hyperthermia and striatal dopaminergic and serotonergic neurotoxicity in male, swiss webster mice (measured as depletions in striatal dopamine and serotonin levels, and reductions in striatal dopamine and serotonin transporter expression levels). |
2014-03-13 |
2023-08-12 |
mouse |
| Julian Macoveanu, James B Rowe, Bettina Hornboll, Rebecca Elliott, Olaf B Paulson, Gitte M Knudsen, Hartwig R Siebne. Playing it safe but losing anyway--serotonergic signaling of negative outcomes in dorsomedial prefrontal cortex in the context of risk-aversion. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 23. issue 8. 2014-03-13. PMID:23051938. |
the same group of participants was studied in three fmri sessions: (i) during intravenous administration of the ssri citalopram to increase the serotonergic tone, (ii) after acute tryptophan depletion (atd) to reduce central serotonin levels, or (iii) without interventions. |
2014-03-13 |
2023-08-12 |
human |
| Ingvar J Rognum, Hoa Tran, Elisabeth A Haas, Keith Hyland, David S Paterson, Robin L Haynes, Kevin G Broadbelt, Brian J Harty, Othon Mena, Henry F Krous, Hannah C Kinne. Serotonin metabolites in the cerebrospinal fluid in sudden infant death syndrome. Journal of neuropathology and experimental neurology. vol 73. issue 2. 2014-03-13. PMID:24423636. |
previously, we reported multiple serotonergic (5-ht) abnormalities in nuclei of the medulla oblongata that help mediate protective responses to homeostatic stressors. |
2014-03-13 |
2023-08-12 |
human |
| María Eugenia Cornide-Petronio, Ramón Anadón, Antón Barreiro-Iglesias, María Celina Rodici. Serotonin 1A receptor (5-HT1A) of the sea lamprey: cDNA cloning and expression in the central nervous system. Brain structure & function. vol 218. issue 5. 2014-03-10. PMID:23052550. |
serotonergic cells are among the earliest neurons to be born in the developing central nervous system and serotonin is known to regulate the development of the nervous system. |
2014-03-10 |
2023-08-12 |
Not clear |
| María Eugenia Cornide-Petronio, Ramón Anadón, Antón Barreiro-Iglesias, María Celina Rodici. Serotonin 1A receptor (5-HT1A) of the sea lamprey: cDNA cloning and expression in the central nervous system. Brain structure & function. vol 218. issue 5. 2014-03-10. PMID:23052550. |
one of the major targets of the activity of serotonergic cells is the serotonin 1a receptor (5-ht1a), an ancestral archetypical serotonin receptor. |
2014-03-10 |
2023-08-12 |
Not clear |
| Steven M Graves, Annika A Viskniskki, Kathryn A Cunningham, T Celeste Napie. Serotonin(2C) receptors in the ventral pallidum regulate motor function in rats. Neuroreport. vol 24. issue 11. 2014-03-05. PMID:23719021. |
serotonergic receptors, including the 5-ht(2c) receptor subtype, are located in the ventral pallidum. |
2014-03-05 |
2023-08-12 |
rat |
| Steven M Graves, Annika A Viskniskki, Kathryn A Cunningham, T Celeste Napie. Serotonin(2C) receptors in the ventral pallidum regulate motor function in rats. Neuroreport. vol 24. issue 11. 2014-03-05. PMID:23719021. |
however, little is known regarding the behavioral consequences of serotonergic transmission in the ventral pallidum, and the role of 5-ht(2c) receptors has not been studied. |
2014-03-05 |
2023-08-12 |
rat |
| Silvina L Diaz, Nicolas Narboux-Nême, Sara Trowbridge, Sophie Scotto-Lomassese, Felix B Kleine Borgmann, Sebastian Jessberger, Bruno Giros, Luc Maroteaux, Evan Deneris, Patricia Gaspa. Paradoxical increase in survival of newborn neurons in the dentate gyrus of mice with constitutive depletion of serotonin. The European journal of neuroscience. vol 38. issue 5. 2014-02-26. PMID:23841816. |
however, the consequences of 5-ht depletion are still unclear as studies using neurotoxins that target serotonergic neurons reached contradictory conclusions on the role of 5-ht on dg cell proliferation. |
2014-02-26 |
2023-08-12 |
mouse |
| A A Coley, V A Ruffin, F J Moss, U Hopfer, W F Boro. Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons. Neuroscience. vol 246. 2014-02-24. PMID:23500099. |
the medullary raphé (mr) of the medulla oblongata contains chemosensitive neurons that respond to increases in arterial [co₂], by altering firing rate, with increases being associated with serotonergic (5-hydroxytryptamine [5ht]) neurons and decreases, with gabaergic neurons. |
2014-02-24 |
2023-08-12 |
mouse |
| Soo-Hyun Park, Yun-Beom Sim, Yu-Jung Kang, Sung-Su Kim, Chea-Ha Kim, Su-Jin Kim, Hong-Won Su. Mechanisms involved in the antinociceptive effects of orally administered oleanolic acid in the mouse. Archives of pharmacal research. vol 36. issue 7. 2014-02-24. PMID:23515934. |
pretreatment with naloxone (opioid receptor antagonist) or methysergide (5-ht serotonergic receptor antagonist) attenuated antinociceptive effect induced by oleanolic acid in the writhing test. |
2014-02-24 |
2023-08-12 |
mouse |