| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Oliver J Robinson, Cassie Overstreet, Philip S Allen, Alison Letkiewicz, Katherine Vytal, Daniel S Pine, Christian Grillo. The role of serotonin in the neurocircuitry of negative affective bias: serotonergic modulation of the dorsal medial prefrontal-amygdala 'aversive amplification' circuit. NeuroImage. vol 78. 2014-01-06. PMID:23583742. |
the role of serotonin in the neurocircuitry of negative affective bias: serotonergic modulation of the dorsal medial prefrontal-amygdala 'aversive amplification' circuit. |
2014-01-06 |
2023-08-12 |
human |
| Oliver J Robinson, Cassie Overstreet, Philip S Allen, Alison Letkiewicz, Katherine Vytal, Daniel S Pine, Christian Grillo. The role of serotonin in the neurocircuitry of negative affective bias: serotonergic modulation of the dorsal medial prefrontal-amygdala 'aversive amplification' circuit. NeuroImage. vol 78. 2014-01-06. PMID:23583742. |
these findings thus provide a promising explanation for the role of serotonin and serotonergic medications in the neurocircuitry of negative affective bias. |
2014-01-06 |
2023-08-12 |
human |
| G Clarke, S Grenham, P Scully, P Fitzgerald, R D Moloney, F Shanahan, T G Dinan, J F Crya. The microbiome-gut-brain axis during early life regulates the hippocampal serotonergic system in a sex-dependent manner. Molecular psychiatry. vol 18. issue 6. 2014-01-03. PMID:22688187. |
concentrations of tryptophan, the precursor of serotonin, are increased in the plasma of male gf animals, suggesting a humoral route through which the microbiota can influence cns serotonergic neurotransmission. |
2014-01-03 |
2023-08-12 |
Not clear |
| Noemí Santana, Guadalupe Mengod, Francesc Artiga. Expression of α(1)-adrenergic receptors in rat prefrontal cortex: cellular co-localization with 5-HT(2A) receptors. The international journal of neuropsychopharmacology. vol 16. issue 5. 2014-01-03. PMID:23195622. |
the high co-expression with 5-ht(2a)rs indicates a convergence of excitatory serotonergic and noradrenergic inputs onto the same neuronal populations. |
2014-01-03 |
2023-08-12 |
rat |
| Shinichi Ogino, Yukinori Nagakura, Mina Tsukamoto, Tomonari Watabiki, Tohru Ozawa, Tomoya Oe, Yasuaki Shimizu, Hiroyuki It. Systemic administration of 5-HT(2C) receptor agonists attenuates muscular hyperalgesia in reserpine-induced myalgia model. Pharmacology, biochemistry, and behavior. vol 108. 2014-01-02. PMID:23603031. |
as dysfunction of serotonergic analgesic control appears to be involved in the pathophysiology of fibromyalgia, the present study explored the potential of 5-ht(2c) receptor agonists as novel therapies for treating this disease. |
2014-01-02 |
2023-08-12 |
rat |
| Ana C Silva, Rossana Perrone, Lucía Zubizarreta, Gervasio Batista, Philip K Stoddar. Neuromodulation of the agonistic behavior in two species of weakly electric fish that display different types of aggression. The Journal of experimental biology. vol 216. issue Pt 13. 2014-01-02. PMID:23761466. |
differences in the telencephalic activity of 5-ht between species were paralleled by a differential serotonergic modulation through 1a receptors that inhibited aggression in the territorial aggression of g. omarorum but not in the reproduction-related aggression of b. gauderio. |
2014-01-02 |
2023-08-12 |
Not clear |
| Bariş O Yildirim, Jan J L Derkse. Systematic review, structural analysis, and new theoretical perspectives on the role of serotonin and associated genes in the etiology of psychopathy and sociopathy. Neuroscience and biobehavioral reviews. vol 37. issue 7. 2013-12-31. PMID:23644029. |
next, it is examined how various polymorphisms in serotonergic genes (e.g., tph, 5htt, htr1a, htr2a, htr2c, and htr3) might contribute either individually or interactively to the development of these disorders and through which specific biological and behavioral endophenotypes this effect could be mediated. |
2013-12-31 |
2023-08-12 |
Not clear |
| Ranganath R Kulkarni, Pratibha R Kulkarn. Linezolid-induced near-fatal serotonin syndrome during escitalopram therapy: case report and review of literature. Indian journal of psychological medicine. vol 35. issue 4. 2013-12-31. PMID:24379509. |
concomitant therapy with an adrenergic or serotonergic agent or consuming tyramine (>100 mg/day) may induce serotonin syndrome (ss). |
2013-12-31 |
2023-08-12 |
Not clear |
| Dara M Cannon, Jacqueline M Klaver, Summer A Klug, Paul J Carlson, David A Luckenbaugh, Masanori Ichise, Wayne C Drevet. Gender-specific abnormalities in the serotonin transporter system in panic disorder. The international journal of neuropsychopharmacology. vol 16. issue 4. 2013-12-27. PMID:22953744. |
the central serotonergic system has been implicated in the pathophysiology of panic disorder (pd) by evidence of abnormally elevated serotonin-turnover, reduced pre- and post-synaptic 5-ht(1a)-receptor sensitivity and binding and clinical improvement during administration of agents that enhance serotonergic transmission. |
2013-12-27 |
2023-08-12 |
human |
| Sebastiaan Engelborghs, Kristel Sleegers, Stefan Van der Mussele, Nathalie Le Bastard, Nathalie Brouwers, Christine Van Broeckhoven, Peter Paul De Dey. Brain-specific tryptophan hydroxylase, TPH2, and 5-HTTLPR are associated with frontal lobe symptoms in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 35. issue 1. 2013-12-27. PMID:23334703. |
a prospective, longitudinal study was set up to investigate possible genetic associations of behavioral and psychological signs and symptoms of dementia (bpsd) in alzheimer's disease (ad) with two candidate genes in the serotonergic neurotransmitter pathway: serotonin transporter (slc6a4) and brain-specific tryptophan hydroxylase (tph2). |
2013-12-27 |
2023-08-12 |
Not clear |
| Christa Hohoff, Ali Gorji, Sylvia Kaiser, Edith Willscher, Eberhard Korsching, Oliver Ambrée, Volker Arolt, Klaus-Peter Lesch, Norbert Sachser, Jürgen Deckert, Lars Lewejohan. Effect of acute stressor and serotonin transporter genotype on amygdala first wave transcriptome in mice. PloS one. vol 8. issue 3. 2013-12-27. PMID:23536833. |
our study therefore disclosed different coping styles dependent on serotonin transporter genotype even directly after the onset of stress and accentuates the role of the serotonergic system in processing stressors and threat in the amygdala. |
2013-12-27 |
2023-08-12 |
mouse |
| Ramesh Chittajallu, Michael T Craig, Ashley McFarland, Xiaoqing Yuan, Scott Gerfen, Ludovic Tricoire, Brian Erkkila, Sean C Barron, Carla M Lopez, Barry J Liang, Brian W Jeffries, Kenneth A Pelkey, Chris J McBai. Dual origins of functionally distinct O-LM interneurons revealed by differential 5-HT(3A)R expression. Nature neuroscience. vol 16. issue 11. 2013-12-27. PMID:24097043. |
these two cohorts differentially participate in network oscillations, with 5-ht(3a)r-containing o-lm cell recruitment dictated by serotonergic tone. |
2013-12-27 |
2023-08-12 |
mouse |
| Zoya Marinova, Susanne Walitza, Edna Grünblat. 5-HT2A serotonin receptor agonist DOI alleviates cytotoxicity in neuroblastoma cells: role of the ERK pathway. Progress in neuro-psychopharmacology & biological psychiatry. vol 44. 2013-12-18. PMID:23380172. |
disturbances of serotonergic signaling, including the serotonin 2a (5-ht2a) receptor, have been implicated in neuropsychiatric and neurodegenerative disorders. |
2013-12-18 |
2023-08-12 |
human |
| A M Agius, N S Jones, R Musca. Serial blood serotonin levels in a randomized controlled trial comparing the efficacy of low-dose amitriptyline, amitriptyline with pindolol and surrogate placebo in patients with chronic tension-type facial pain. Rhinology. vol 51. issue 3. 2013-12-17. PMID:23943730. |
descending serotonergic neuronal projections are known to modulate pain and intra-platelet serotonin levels are an accepted model reflecting central intra-neuronal serotonin. |
2013-12-17 |
2023-08-12 |
Not clear |
| Chiara Bianca Maria Platania, Gian Marco Leggio, Filippo Drago, Salvatore Salomone, Claudio Bucol. Regulation of intraocular pressure in mice: structural analysis of dopaminergic and serotonergic systems in response to cabergoline. Biochemical pharmacology. vol 86. issue 9. 2013-12-17. PMID:23962442. |
to investigate the contribution of dopaminergic and serotonergic systems in iop regulation, we used cabergoline, a mixed dopamine and serotonin agonist, in c57bl/6j wt and dopamine d₃ receptor knock-out (d₃r⁻/⁻) mice with normal eye pressure or steroid-induced ocular hypertension. |
2013-12-17 |
2023-08-12 |
mouse |
| Syed Ziaur Rahman, Jim Basilakis, Anton Rahmadi, Sanja Lujic, Ian Musgrave, Louisa Jorm, Phillipa Hay, Gerald Münc. Use of serotonergic antidepressants and St John's wort in older Australians: a population-based cohort study. Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists. vol 21. issue 3. 2013-12-11. PMID:23439542. |
the study investigated the use of serotonergic antidepressants (ssris: selective serotonin reuptake inhibitors; snris: serotonin-norepinephrine reuptake inhibitors) and st john's wort in a large nsw-based community sample, and sought to identify a potentially dangerous concomitant use of these medications. |
2013-12-11 |
2023-08-12 |
Not clear |
| Gül Dölen, Ayeh Darvishzadeh, Kee Wui Huang, Robert C Malenk. Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin. Nature. vol 501. issue 7466. 2013-12-11. PMID:24025838. |
although the nucleus accumbens receives oxytocin-receptor-containing inputs from several brain regions, genetic deletion of these receptors specifically from dorsal raphe nucleus, which provides serotonergic (5-hydroxytryptamine; 5-ht) innervation to the nucleus accumbens, abolishes the reinforcing properties of social interaction. |
2013-12-11 |
2023-08-12 |
mouse |
| Martilias S Farrell, Bryan L Rot. Pharmacosynthetics: Reimagining the pharmacogenetic approach. Brain research. vol 1511. 2013-12-09. PMID:23063887. |
thus, for instance, serotonergic activation of 5-ht(2a) receptors in rat aortic smooth muscle cells leads to an increase in intracellular ca(++) (via ip₃ release) and smooth muscle contraction (roth et al., 1986). |
2013-12-09 |
2023-08-12 |
rat |
| Eric Promme. Olanzapine: palliative medicine update. The American journal of hospice & palliative care. vol 30. issue 1. 2013-12-03. PMID:22495793. |
olanzapine blocks multiple neurotransmitter receptors, including dopaminergic (d(1), d(2), d(3), and d(4)), serotonergic (5-hydroxytryptamine 2a [5-ht(2a)], 5-ht(2c), 5-ht(3), and 5-ht(6)), adrenergic (α(1)), histaminic (h(1)), and muscarinic (m(1), m(2), m(3), and m(4)) receptors. |
2013-12-03 |
2023-08-12 |
Not clear |
| Esther Asan, Maria Steinke, Klaus-Peter Lesc. Serotonergic innervation of the amygdala: targets, receptors, and implications for stress and anxiety. Histochemistry and cell biology. vol 139. issue 6. 2013-12-03. PMID:23494464. |
the fact that altered amygdala activity patterns are observed upon pharmacological manipulations of serotonergic transmission, as well as in carriers of genetic variations in serotonin pathway-associated signaling molecules representing risk factors for neuropsychiatric disorders, underlines the importance of understanding the role and mode of action of serotonergic transmission in the amygdala for human psychopathology. |
2013-12-03 |
2023-08-12 |
human |