| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Naozumi Araragi, Klaus-Peter Lesc. Serotonin (5-HT) in the regulation of depression-related emotionality: insight from 5-HT transporter and tryptophan hydroxylase-2 knockout mouse models. Current drug targets. vol 14. issue 5. 2013-10-29. PMID:23547810. |
here, we first highlight basic characteristics of the serotonergic system including the biosynthesis of 5-ht as well as the anatomy and firing activity of serotonergic neurons. |
2013-10-29 |
2023-08-12 |
mouse |
| Collin Challis, Janette Boulden, Avin Veerakumar, Julie Espallergues, Fair M Vassoler, R Christopher Pierce, Sheryl G Beck, Olivier Berto. Raphe GABAergic neurons mediate the acquisition of avoidance after social defeat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 35. 2013-10-28. PMID:23986235. |
we tested this hypothesis using whole-cell recording techniques in genetically identified drn gaba and 5-ht neurons in mice exposed to social defeat, a model that induces long-lasting avoidance behaviors in a subset of mice responsive to serotonergic antidepressants. |
2013-10-28 |
2023-08-12 |
mouse |
| Arne Mørk, Liliana P Montezinho, Silke Miller, Crista Trippodi-Murphy, Niels Plath, Yan Li, Maria Gulinello, Connie Sanche. Vortioxetine (Lu AA21004), a novel multimodal antidepressant, enhances memory in rats. Pharmacology, biochemistry, and behavior. vol 105. 2013-10-23. PMID:23380522. |
the serotonergic system plays an important role in cognitive functions via various 5-ht receptors. |
2013-10-23 |
2023-08-12 |
rat |
| Adam Michael Stewart, Jonathan Cachat, Siddharth Gaikwad, Kyle S L Robinson, Michael Gebhardt, Allan V Kaluef. Perspectives on experimental models of serotonin syndrome in zebrafish. Neurochemistry international. vol 62. issue 6. 2013-10-22. PMID:23485557. |
serotonin syndrome (ss) is a serious life-threatening disorder associated with elevated brain serotonergic function. |
2013-10-22 |
2023-08-12 |
zebrafish |
| M B Llewelyn, J Azami, M H Robert. Effects of 5-hydroxytryptamine applied into nucleus raphe magnus on nociceptive thresholds and neuronal firing rate. Brain research. vol 258. issue 1. 2013-10-22. PMID:24010164. |
the excitatory response to 5-hydroxytryptamine was reduced by the putative serotonergic antagonist cinanserin in 21 of 24 cases. |
2013-10-22 |
2023-08-12 |
rat |
| Tushar Arora, Malay Bhowmik, Razia Khanam, Divya Vohor. Oxcarbazepine and fluoxetine protect against mouse models of obsessive compulsive disorder through modulation of cortical serotonin and CREB pathway. Behavioural brain research. vol 247. 2013-10-21. PMID:23473877. |
the serotonergic system is suggested to be dysregulated in obsessive compulsive disorder (ocd) as selective serotonin reuptake inhibitors have emerged as the mainstay in the treatment of this disorder. |
2013-10-21 |
2023-08-12 |
mouse |
| YoneJung Yoon, Morgan C McKenna, David A Rollins, Minseok Song, Tal Nuriel, Steven S Gross, Guoqiang Xu, Charles E Glat. Anxiety-associated alternative polyadenylation of the serotonin transporter mRNA confers translational regulation by hnRNPK. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 28. 2013-10-18. PMID:23798440. |
the serotonin transporter (sert) is a major regulator of serotonergic neurotransmission and anxiety-related behaviors. |
2013-10-18 |
2023-08-12 |
mouse |
| Randy A Sansone, Lori A Sanson. Sunshine, serotonin, and skin: a partial explanation for seasonal patterns in psychopathology? Innovations in clinical neuroscience. vol 10. issue 7-8. 2013-10-18. PMID:24062970. |
human skin has an inherent serotonergic system that appears capable of generating serotonin. |
2013-10-18 |
2023-08-12 |
human |
| K Suriyaprom, B Phonrat, U Chuensumran, A Tungtrongchitr, R Tungtrongchit. Association of HTTLPR and 5-HT₂A T102C polymorphisms with smoking characteristics and anthropometric profiles of Thai males. Genetics and molecular research : GMR. vol 11. issue 4. 2013-10-17. PMID:23096916. |
we investigated a possible association between two polymorphisms in the serotonergic system - httlpr of a serotonin transporter gene and 5-ht(2a) at position t102c - with biochemical and anthropometric parameters, and with cigarette smoking in an investigation of 200 smokers and 111 non-smokers. |
2013-10-17 |
2023-08-12 |
human |
| A W Moreau, M Amar, J Callebert, P Fossie. Serotonergic modulation of LTP at excitatory and inhibitory synapses in the developing rat visual cortex. Neuroscience. vol 238. 2013-10-17. PMID:23454367. |
to infer the role of serotonergic neuromodulation on the activity-dependent maintenance of the e-i balance, we performed continuous voltage clamp measurements of stimulation-locked conductance dynamics in layer 5 pyramidal neurons before and after long-term potentiation (ltp) induction, together with chronic or acute manipulation of serotonin function. |
2013-10-17 |
2023-08-12 |
rat |
| Elena Gardella, Cristina Romei, Anna Cavallero, Claudio Trapella, Ernesto Fedele, Luca Raiter. Neuropeptide S inhibits release of 5-HT and glycine in mouse amygdala and frontal/prefrontal cortex through activation of the neuropeptide S receptor. Neurochemistry international. vol 62. issue 4. 2013-09-20. PMID:23411412. |
in conclusion, nps can inhibit the exocytosis of 5-ht and of glycine through the activation of presynaptic npsrs situated on serotonergic and glycinergic terminals in areas involved in fear/anxiety behaviours. |
2013-09-20 |
2023-08-12 |
mouse |
| Marc N Potenza, Espen Walderhaug, Shannan Henry, Jean-Dominique Gallezot, Beata Planeta-Wilson, Jim Ropchan, Alexander Neumeiste. Serotonin 1B receptor imaging in pathological gambling. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 14. issue 2. 2013-09-13. PMID:21936763. |
although serotonergic mechanisms have been implicated in pathological gambling (pg), no ligand-based imaging studies have assessed serotonin receptors in individuals with pg. |
2013-09-13 |
2023-08-12 |
human |
| Stuart I Hodgetts, Paul J Simmons, Giles W Plan. Human mesenchymal precursor cells (Stro-1⁺) from spinal cord injury patients improve functional recovery and tissue sparing in an acute spinal cord injury rat model. Cell transplantation. vol 22. issue 3. 2013-09-13. PMID:23007022. |
immunohistochemical analysis revealed increased serotonergic (5-ht) and sensory (cgrp) axonal growth within and surrounding transplanted donor hmpcs 2 weeks posttransplantation, but no evidence of hmpc transdifferentiation was seen. |
2013-09-13 |
2023-08-12 |
human |
| Florence Razoux, Christof Baltes, Thomas Mueggler, Aline Seuwen, Holger Russig, Isabelle Mansuy, Markus Rudi. Functional MRI to assess alterations of functional networks in response to pharmacological or genetic manipulations of the serotonergic system in mice. NeuroImage. vol 74. 2013-09-13. PMID:23454471. |
since the serotonergic receptor 1a (5-ht(1a)-r) has been strongly implicated in the pathophysiology of depressive and anxiety disorders, as well as in the action of antidepressant drugs, we investigated brain connectivity related to the 5-ht(1a)-r system by use of pharmacological functional magnetic resonance imaging in mice. |
2013-09-13 |
2023-08-12 |
mouse |
| Stephanie B Linley, Walter B Hoover, Robert P Verte. Pattern of distribution of serotonergic fibers to the orbitomedial and insular cortex in the rat. Journal of chemical neuroanatomy. vol 48-49. 2013-09-12. PMID:23337940. |
as is well recognized, serotonergic (5-ht) fibers distribute widely throughout the brain, including the cerebral cortex. |
2013-09-12 |
2023-08-12 |
rat |
| Patrick M Fisher, Ahmad R Harir. Identifying serotonergic mechanisms underlying the corticolimbic response to threat in humans. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 368. issue 1615. 2013-09-12. PMID:23440464. |
serotonin is a potent neuromodulator of this circuit; however, specific serotonergic mechanisms mediating these effects are not fully understood. |
2013-09-12 |
2023-08-12 |
Not clear |
| Linda Booij, Dongsha Wang, Mélissa L Lévesque, Richard E Tremblay, Moshe Szy. Looking beyond the DNA sequence: the relevance of DNA methylation processes for the stress-diathesis model of depression. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 368. issue 1615. 2013-09-12. PMID:23440465. |
the functioning of the hypothalamic-pituitary-adrenal (hpa) axis and serotonergic (5-ht) system are known to be intertwined with mood. |
2013-09-12 |
2023-08-12 |
human |
| Kohji Sat. Placenta-derived hypo-serotonin situations in the developing forebrain cause autism. Medical hypotheses. vol 80. issue 4. 2013-09-11. PMID:23375670. |
recently, it has been reported that placenta-derived serotonin is the main source in embryonic day (e) 10-15 mouse forebrain, after that period, the serotonergic fibers start to supply serotonin into the forebrain. |
2013-09-11 |
2023-08-12 |
mouse |
| Kohji Sat. Placenta-derived hypo-serotonin situations in the developing forebrain cause autism. Medical hypotheses. vol 80. issue 4. 2013-09-11. PMID:23375670. |
the paucity of serotonin in the forebrain also causes over-growth of serotonergic fibers. |
2013-09-11 |
2023-08-12 |
mouse |
| Ellen Shopes, Wayne Gerard, Jessica Baughma. Methylene blue encephalopathy: a case report and review of published cases. AANA journal. vol 81. issue 3. 2013-09-03. PMID:23923673. |
it has been suggested that in susceptible individuals an interaction occurs between methylene blue and serotonergic agents that precipitates serotonin syndrome. |
2013-09-03 |
2023-08-12 |
Not clear |