| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wan-Hui Lin, Hua-Pin Huang, Ming-Xing Lin, Sheng-Gen Chen, Xiao-Chai Lv, Chun-Hui Che, Ji-Lan Li. Seizure-induced 5-HT release and chronic impairment of serotonergic function in rats. Neuroscience letters. vol 534. 2013-06-18. PMID:23276638. |
to identify serotonergic neurons in the raphe nuclei (a major source of 5-ht release in the brain), brain sections were immunostained for tryptophan hydroxylase (tph). |
2013-06-18 |
2023-08-12 |
rat |
| Wan-Hui Lin, Hua-Pin Huang, Ming-Xing Lin, Sheng-Gen Chen, Xiao-Chai Lv, Chun-Hui Che, Ji-Lan Li. Seizure-induced 5-HT release and chronic impairment of serotonergic function in rats. Neuroscience letters. vol 534. 2013-06-18. PMID:23276638. |
these data suggest that pilocarpine induces depletion of 5-ht in the hippocampus and significantly compromise serotonergic neurons in the raphe nuclei. |
2013-06-18 |
2023-08-12 |
rat |
| Melina Ellis, Jordan D Chambers, Rachel M Gwynne, Joel C Bornstei. Serotonin and cholecystokinin mediate nutrient-induced segmentation in guinea pig small intestine. American journal of physiology. Gastrointestinal and liver physiology. vol 304. issue 8. 2013-06-17. PMID:23392236. |
serotonergic and cck-related mechanisms underlying nutrient-induced segmentation were investigated using selective 5-ht and cck receptor antagonists on isolated segments of small intestine luminally perfused with 1 mm decanoic acid. |
2013-06-17 |
2023-08-12 |
Not clear |
| Roger D Longley, Misa Peterma. Neuronal control of pedal sole cilia in the pond snail Lymnaea stagnalis appressa. Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology. vol 199. issue 1. 2013-06-14. PMID:23124910. |
5-ht (serotonin) is a ubiquitous neurotransmitter that produces ciliary beating in gastropods when applied topically, but ciliary beating caused by gastropod serotonergic neurons has been described in only three neuron pairs. |
2013-06-14 |
2023-08-12 |
Not clear |
| M Tanaka, K Csabafi, G Telegd. Neurotransmissions of antidepressant-like effects of kisspeptin-13. Regulatory peptides. vol 180. 2013-06-10. PMID:22999921. |
the mice were pretreated with a nonselective α-adrenergic receptor antagonist, phenoxybenzamine, an α(1)/α(2β)-adrenergic receptor antagonist, prazosin, an α(2)-adrenergic receptor antagonist, yohimbine, a β-adrenergic receptor antagonist, propranolol, a mixed 5-ht(1)/5-ht(2) serotonergic receptor antagonist, methysergide, a nonselective 5-ht(2) serotonergic receptor antagonist, cyproheptadine, a nonselective muscarinic acetylcholine receptor antagonist, atropine, a d(2),d(3),d(4) dopamine receptor antagonist, haloperidol, or a γ-aminobutyric acid subunit a receptor antagonist, bicuculline. |
2013-06-10 |
2023-08-12 |
mouse |
| M Tanaka, K Csabafi, G Telegd. Neurotransmissions of antidepressant-like effects of kisspeptin-13. Regulatory peptides. vol 180. 2013-06-10. PMID:22999921. |
the results demonstrated that the antidepressant-like effects of kisspeptin-13 in a modified mouse fst are mediated, at least in part, by an interaction of the α(2)-adrenergic and 5-ht(2) serotonergic receptors. |
2013-06-10 |
2023-08-12 |
mouse |
| Lauren B Burhans, Carrie A Smith-Bell, Bernard G Schreur. Subacute fluoxetine enhances conditioned responding and conditioning-specific reflex modification of the rabbit nictitating membrane response: implications for drug treatment with selective serotonin reuptake inhibitors. Behavioural pharmacology. vol 24. issue 1. 2013-06-10. PMID:23263485. |
the aim of the current study was to examine the sensitivity of the crm paradigm to serotonergic manipulation with fluoxetine, a commonly prescribed selective serotonin reuptake inhibitor for anxiety disorders. |
2013-06-10 |
2023-08-12 |
rabbit |
| Takashi Maejima, Olivia A Masseck, Melanie D Mark, Stefan Herlitz. Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels. Frontiers in integrative neuroscience. vol 7. 2013-06-05. PMID:23734105. |
therefore, serotonin release and serotonergic neuronal activity have to be precisely controlled and modulated by interacting brain circuits to adapt to specific emotional and environmental states. |
2013-06-05 |
2023-08-12 |
Not clear |
| Takashi Maejima, Olivia A Masseck, Melanie D Mark, Stefan Herlitz. Modulation of firing and synaptic transmission of serotonergic neurons by intrinsic G protein-coupled receptors and ion channels. Frontiers in integrative neuroscience. vol 7. 2013-06-05. PMID:23734105. |
we will review the current knowledge about g protein-coupled receptors and ion channels involved in the regulation of serotonergic system, how their regulation is modulating the intrinsic activity of serotonergic neurons and its transmitter release and will discuss the latest methods for controlling the modulation of serotonin release and intracellular signaling in serotonergic neurons in vitro and in vivo. |
2013-06-05 |
2023-08-12 |
Not clear |
| Steven J Montague, Keith K Fenrich, Colin Mayer-Macaulay, Robert Maratta, Monica S Neuber-Hess, P Ken Ros. Nonuniform distribution of contacts from noradrenergic and serotonergic boutons on the dendrites of cat splenius motoneurons. The Journal of comparative neurology. vol 521. issue 3. 2013-06-03. PMID:22821606. |
the goal of the present study was to quantify the number and distribution of synapses from two powerful neuromodulatory systems that originate from noradrenergic (na) and serotonergic (5-ht) neurons. |
2013-06-03 |
2023-08-12 |
cat |
| William O Ogle, Rachel B Speisman, Brandi K Ormero. Potential of treating age-related depression and cognitive decline with nutraceutical approaches: a mini-review. Gerontology. vol 59. issue 1. 2013-05-29. PMID:22947921. |
structurally similar polyphenolics such as curcumin, resveratrol, and proanthocyanidins exhibit antioxidant and immunomodulatory properties and recent research suggests that they also modulate hypothalamic-pituitary-adrenal (hpa) axis activity, serotonergic transmission and hippocampal neurogenesis (perhaps via their effects on serotonin and hpa activity). |
2013-05-29 |
2023-08-12 |
Not clear |
| Kun Zhang, Haiyun Xu, Longlong Cao, Kangsheng Li, Qingjun Huan. Interleukin-1β inhibits the differentiation of hippocampal neural precursor cells into serotonergic neurons. Brain research. vol 1490. 2013-05-29. PMID:23085314. |
at the endpoint, the serotonergic differentiation of hippocampal npcs in il-1β-treated cultures decreased in a dose-dependent manner and this effect was blocked by il-1ra, an il-1 receptor antagonist capable of blocking the effects of il-1 by binding to the same receptor (il-1r1) without triggering signaling; serotonin in the lysate of the differentiated hippocampal npcs decreased in il-1β-treated cultures; and levels of bcl-2 and phosphorylated extracellular-regulated kinase (perk) were also lower in differentiated hippocampal npcs with il-1β treatment. |
2013-05-29 |
2023-08-12 |
rat |
| David Elmenhorst, Tina Kroll, Andreas Matusch, Andreas Baue. Sleep deprivation increases cerebral serotonin 2A receptor binding in humans. Sleep. vol 35. issue 12. 2013-05-24. PMID:23204604. |
the aim of the current study is to investigate the effect of 24-h total sleep deprivation on the apparent serotonin 2a receptor (5-ht(2a)r) binding capacity in the human brain to test the hypothesis that sleep deprivation induces global molecular alterations in the cortical serotonergic receptor system. |
2013-05-24 |
2023-08-12 |
human |
| Shruti Kant, Erica Liebel. Recognizing serotonin toxicity in the pediatric emergency department. Pediatric emergency care. vol 28. issue 8. 2013-05-21. PMID:22863827. |
the objectives of this article are to review specific serotonergic medications including their adverse effects and toxicity in overdose, to describe other medications/substances that have proserotonergic effects, which could result in serotonin excess in combination with traditional serotonergic agents, and to define the criteria for serotonin syndrome/toxicity and its treatment. |
2013-05-21 |
2023-08-12 |
Not clear |
| Junlin Zhang, Katie A Dennis, Ryan D Darling, Loai Alzghoul, Ian A Paul, Kimberly L Simpson, Rick C S Li. Neonatal citalopram exposure decreases serotonergic fiber density in the olfactory bulb of male but not female adult rats. Frontiers in cellular neuroscience. vol 7. 2013-05-16. PMID:23675318. |
manipulation of serotonin (5ht) during early development has been shown to induce long-lasting morphological changes within the raphe nuclear complex and serotonergic circuitry throughout the brain. |
2013-05-16 |
2023-08-12 |
rat |
| Junlin Zhang, Katie A Dennis, Ryan D Darling, Loai Alzghoul, Ian A Paul, Kimberly L Simpson, Rick C S Li. Neonatal citalopram exposure decreases serotonergic fiber density in the olfactory bulb of male but not female adult rats. Frontiers in cellular neuroscience. vol 7. 2013-05-16. PMID:23675318. |
since the serotonergic raphe nuclear complex projects to the olfactory bulb (ob) and perinatal 5ht disruption has been shown to disrupt olfactory behaviors, the goal of this study was to further investigate such developmental effects in the ob of ctm exposed animals. |
2013-05-16 |
2023-08-12 |
rat |
| Louise M Paterson, Birgitte R Kornum, David J Nutt, Victor W Pike, Gitte M Knudse. 5-HT radioligands for human brain imaging with PET and SPECT. Medicinal research reviews. vol 33. issue 1. 2013-05-14. PMID:21674551. |
the serotonergic system plays a key modulatory role in the brain and is the target for many drug treatments for brain disorders either through reuptake blockade or via interactions at the 14 subtypes of 5-ht receptors. |
2013-05-14 |
2023-08-12 |
human |
| Madelene Åberg Andersson, Erik Höglun. Linking personality to larval energy reserves in rainbow trout (Oncorhynchus mykiss). PloS one. vol 7. issue 11. 2013-05-09. PMID:23155473. |
furthermore, socially naïve larvae with big yolks had lower serotonin levels, suggesting that other factors than the social environment causes variation in serotonergic transmission, underlying individual variation in aggressive behavior. |
2013-05-09 |
2023-08-12 |
Not clear |
| I Heitland, R S Oosting, J M P Baas, S A A Massar, J L Kenemans, K B E Böcke. Genetic polymorphisms of the dopamine and serotonin systems modulate the neurophysiological response to feedback and risk taking in healthy humans. Cognitive, affective & behavioral neuroscience. vol 12. issue 4. 2013-05-03. PMID:22810728. |
here, we studied the effects of dopaminergic (dopamine transporter [dat1], catecholamine-o-methyltransferase val158met [comt]) and serotonergic (serotonin transporter [5httlpr]) polymorphisms on risk taking and brain responses following feedback in 60 healthy female subjects. |
2013-05-03 |
2023-08-12 |
human |
| Mohammad M Iqbal, Miles J Basil, Jonathan Kaplan, Md Touhid Iqba. Overview of serotonin syndrome. Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists. vol 24. issue 4. 2013-05-03. PMID:23145389. |
serotonin syndrome (ss) is a rare and potentially life-threatening toxic state caused by an adverse drug reaction that leads to excessive central and peripheral serotonergic activity. |
2013-05-03 |
2023-08-12 |
Not clear |