| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Özgür Devrim Can, Ümide Demir Özkay, Umut İrfan Üçe. Anti-depressant-like effect of vitexin in BALB/c mice and evidence for the involvement of monoaminergic mechanisms. European journal of pharmacology. vol 699. issue 1-3. 2013-09-02. PMID:23099258. |
these results suggest that the anti-depressant-like effect of vitexin is mediated through an increase in catecholamine levels in the synaptic cleft as well as through interactions with the serotonergic 5-ht(1a), noradrenergic α(2), and dopaminergic d(1), d(2), and d(3) receptors. |
2013-09-02 |
2023-08-12 |
mouse |
| Akiko Oyabu, Masaaki Narita, Yasura Tashir. The effects of prenatal exposure to valproic acid on the initial development of serotonergic neurons. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 31. issue 3. 2013-08-30. PMID:23376409. |
an abnormal serotonergic (5-ht) system has been implicated in the etiology of asd. |
2013-08-30 |
2023-08-12 |
rat |
| Michael Kometer, André Schmidt, Lutz Jäncke, Franz X Vollenweide. Activation of serotonin 2A receptors underlies the psilocybin-induced effects on α oscillations, N170 visual-evoked potentials, and visual hallucinations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 25. 2013-08-30. PMID:23785166. |
although the serotonergic hallucinogen psilocybin activates multiple serotonin (5-ht) receptors, recent evidence suggests that activation of 5-ht2a receptors may lead to the formation of visual hallucinations by increasing cortical excitability and altering visual-evoked cortical responses. |
2013-08-30 |
2023-08-12 |
human |
| S Yubero-Lahoz, P Robledo, M Farré, R de laTorr. Platelet SERT as a peripheral biomarker of serotonergic neurotransmission in the central nervous system. Current medicinal chemistry. vol 20. issue 11. 2013-08-28. PMID:23409709. |
the serotonin (5-hydroxytryptamine; 5-ht) transporter(sert) in the brain clears 5-ht from extracellular spaces, modulating the strength and duration of serotonergic signaling.outside the central nervous system, it is also present in platelets, where it takes up 5-ht from plasma, keeping levels very low (i.e., ~1 nm). |
2013-08-28 |
2023-08-12 |
human |
| Thomas L Schwartz, Umar A Siddiqui, Stephen M Stah. Vilazodone: a brief pharmacological and clinical review of the novel serotonin partial agonist and reuptake inhibitor. Therapeutic advances in psychopharmacology. vol 1. issue 3. 2013-08-28. PMID:23983930. |
its putative mechanism of antidepressant action enhances the release of serotonin across the brain's serotonergic pathways specifically by inhibiting the serotonin transporter, similar to a selective serotonin reuptake inhibitor (ssri), and simultaneously stimulating serotonin-1a receptors via partial agonism, similar to the anxiolytic bus-pirone. |
2013-08-28 |
2023-08-12 |
Not clear |
| Shasha Zhang, Yan Liu, Yi Ra. Serotonin signaling in the brain of adult female mice is required for sexual preference. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 24. 2013-08-23. PMID:23716677. |
here we show that female mouse mutants lacking either central serotonergic neurons or serotonin prefer female over male genital odors when given a choice, and displayed increased female-female mounting when presented either with a choice of a male and a female target or only with a female target. |
2013-08-23 |
2023-08-12 |
mouse |
| Meaghan C Creed, José N Nobreg. The role of serotonin in the antidyskinetic effects of deep brain stimulation: focus on antipsychotic-induced motor symptoms. Reviews in the neurosciences. vol 24. issue 2. 2013-08-21. PMID:23399586. |
we also discuss the evidence for dbs-induced alterations in 5-ht function and the relevance of serotonergic alterations to the antidyskinetic effects of dbs. |
2013-08-21 |
2023-08-12 |
Not clear |
| Alain M Gardie. Antidepressant activity: contribution of brain microdialysis in knock-out mice to the understanding of BDNF/5-HT transporter/5-HT autoreceptor interactions. Frontiers in pharmacology. vol 4. 2013-08-21. PMID:23964240. |
the inhibitory role of serotonergic autoreceptors infers that they limit somatodendritic and nerve terminal 5-ht release. |
2013-08-21 |
2023-08-12 |
mouse |
| Moritz Lebe, Monika I Hasenbring, Kirsten Schmieder, Kathleen Jetschke, Albrecht Harders, Jörg T Epplen, Sabine Hoffjan, Judith Köttin. Association of serotonin-1A and -2A receptor promoter polymorphisms with depressive symptoms, functional recovery, and pain in patients 6 months after lumbar disc surgery. Pain. vol 154. issue 3. 2013-08-15. PMID:23318131. |
single nucleotide polymorphisms (snps) in the serotonergic (5ht) system seem to have modulatory effects on depression and physical function. |
2013-08-15 |
2023-08-12 |
Not clear |
| Yoshihiro Gocho, Atsushi Sakai, Yuchio Yanagawa, Hidenori Suzuki, Fumihito Saito. Electrophysiological and pharmacological properties of GABAergic cells in the dorsal raphe nucleus. The journal of physiological sciences : JPS. vol 63. issue 2. 2013-08-12. PMID:23275149. |
especially, we examined postsynaptic responses mediated by 5-ht receptors between gabaergic and serotonergic cells in the drn. |
2013-08-12 |
2023-08-12 |
mouse |
| Naozumi Araragi, Boris Mlinar, Gilda Baccini, Lise Gutknecht, Klaus-Peter Lesch, Renato Corradett. Conservation of 5-HT1A receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis. Frontiers in pharmacology. vol 4. 2013-08-12. PMID:23935583. |
here, we investigated how persistent alterations in brain 5-ht availability affect autoinhibition in two genetically modified mouse models lacking critical mediators of serotonergic transmission: 5-ht transporter knockout (sert-/-) and tryptophan hydroxylase-2 knockout (tph2-/-) mice. |
2013-08-12 |
2023-08-12 |
mouse |
| Naozumi Araragi, Boris Mlinar, Gilda Baccini, Lise Gutknecht, Klaus-Peter Lesch, Renato Corradett. Conservation of 5-HT1A receptor-mediated autoinhibition of serotonin (5-HT) neurons in mice with altered 5-HT homeostasis. Frontiers in pharmacology. vol 4. 2013-08-12. PMID:23935583. |
changes in 5-ht1a receptor sensitivity may rather be seen as an adaptive mechanism to keep autoinhibition functioning in response to extremely altered levels of extracellular 5-ht resulting from targeted inactivation of mediators of serotonergic signaling. |
2013-08-12 |
2023-08-12 |
mouse |
| Chiung-Chun Huang, Che-Ming Yeh, Mei-Ying Wu, Kuei-Sen Hs. A single in vivo cocaine administration impairs 5-HT(1B) receptor-induced long-term depression in the nucleus accumbens. Journal of neurochemistry. vol 125. issue 6. 2013-08-06. PMID:23452061. |
while nac neurons are richly innervated by serotonergic fibers, information on the functional role of serotonin 5-hydroxytryptamine (5-ht) in the nac is still sparse. |
2013-08-06 |
2023-08-12 |
mouse |
| Hidenori Aizawa, Shin Yanagihara, Megumi Kobayashi, Kazue Niisato, Takashi Takekawa, Rie Harukuni, Thomas J McHugh, Tomoki Fukai, Yoshikazu Isomura, Hitoshi Okamot. The synchronous activity of lateral habenular neurons is essential for regulating hippocampal theta oscillation. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 20. 2013-08-02. PMID:23678132. |
since serotonin is known to negatively regulate theta oscillation in the hippocampus, phase-locking activity of the lhb neurons may act, under the influence of the dbb, to maintain the hippocampal theta oscillation by modulating the activity of serotonergic neurons. |
2013-08-02 |
2023-08-12 |
rat |
| Andrea J Rapkin, Judith A Mikacic. Premenstrual dysphoric disorder and severe premenstrual syndrome in adolescents. Paediatric drugs. vol 15. issue 3. 2013-07-30. PMID:23529867. |
serotonergic agonists are a first-line therapy for adults, and some serotonin reuptake inhibitors such as fluoxetine and escitalopram can be administered safely to teens. |
2013-07-30 |
2023-08-12 |
Not clear |
| Bernd Pelster, Thorsten Schwert. The paracrine role of 5-HT in the control of gill blood flow. Respiratory physiology & neurobiology. vol 184. issue 3. 2013-07-29. PMID:22652438. |
serotonergic nerves as well as neuroepithelial cells have been shown to release serotonin, while very little is known about the polymorphous granular cells. |
2013-07-29 |
2023-08-12 |
Not clear |
| S Willemen, L Che, M De Vos, V Huygelen, B Tambuyzer, C Casteleyn, S Van Cruchten, K Zhang, C Van Ginneke. Perinatal growth restriction is not related to higher intestinal distribution and increased serum levels of 5-hydroxytryptamin in piglets. Journal of animal science. vol 90 Suppl 4. 2013-07-29. PMID:23365362. |
hence, the density of intestinal 5-ht cells in fetal and neonatal sga piglets was compared with serotonergic cell density in normal weight (nw) littermates. |
2013-07-29 |
2023-08-12 |
human |
| Morteza Zendehdel, Kasra Mokhtarpouriani, Farshid Hamidi, Rohollah Montazer. Intracerebroventricular injection of ghrelin produces hypophagia through central serotonergic mechanisms in chicken. Veterinary research communications. vol 37. issue 1. 2013-07-25. PMID:23065457. |
these results suggest that hypophagic effect of ghrelin probably is mediated by serotonergic mechanisms via 5-ht(2c) receptor. |
2013-07-25 |
2023-08-12 |
chicken |
| Nicholas Patocka, Paula Ribeir. The functional role of a serotonin transporter in Schistosoma mansoni elucidated through immunolocalization and RNA interference (RNAi). Molecular and biochemical parasitology. vol 187. issue 1. 2013-07-17. PMID:23246818. |
co-localization experiments showed that the pattern of smsert expression coincides with that of serotonin itself, suggesting that smsert is present in serotonergic neurons. |
2013-07-17 |
2023-08-12 |
Not clear |
| Jeffrey L Barr, Jamie L Scholl, Rajeshwari R Solanki, Michael J Watt, Christopher A Lowry, Kenneth J Renner, Gina L Forste. Influence of chronic amphetamine treatment and acute withdrawal on serotonin synthesis and clearance mechanisms in the rat ventral hippocampus. The European journal of neuroscience. vol 37. issue 3. 2013-07-15. PMID:23157166. |
serotonin synthesis (assessed by accumulation of serotonin precursor as a measure of the capacity of in vivo tryptophan hydroxylase activity), expression of serotonergic transporters, and in vivo serotonergic clearance using in vivo microdialysis were assessed in the ventral hippocampus in adult male sprague dawley rats at 24 h withdrawal from chronic amphetamine. |
2013-07-15 |
2023-08-12 |
rat |