| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Coppola, Brett R Wenner, Olga Ilkayeva, Robert D Stevens, Mauro Maggioni, Theodore A Slotkin, Edward D Levin, Christopher B Newgar. Branched-chain amino acids alter neurobehavioral function in rats. American journal of physiology. Endocrinology and metabolism. vol 304. issue 4. 2013-04-05. PMID:23249694. |
the anxiety-like behaviors and decreased levels of trp in the brain of bcaa-fed rats were reversed by supplementation of trp in the drinking water but not by administration of fluoxetine, a selective serotonin reuptake inhibitor, suggesting that the behavioral changes are independent of the serotonergic pathway of trp metabolism. |
2013-04-05 |
2023-08-12 |
human |
| R Avula, A Rand, J L Black, D J O'Kan. Simultaneous genotyping of multiple polymorphisms in human serotonin transporter gene and detection of novel allelic variants. Translational psychiatry. vol 1. 2013-04-04. PMID:22832606. |
the serotonin transporter, called slc6a4, sert or 5-htt, modulates neurotransmission by removal of serotonin from the synapse of serotonergic neurons, facilitating serotonin reuptake into the presynaptic terminus. |
2013-04-04 |
2023-08-12 |
human |
| J M Launay, S Mouillet-Richard, A Baudry, M Pietri, O Kellerman. Raphe-mediated signals control the hippocampal response to SRI antidepressants via miR-16. Translational psychiatry. vol 1. 2013-04-04. PMID:22833211. |
fluoxetine, acting on serotonergic raphe neurons, decreases the amount of mir-16 in the hippocampus, which in turn increases the levels of the serotonin transporter (sert), the target of sri, and that of bcl-2 and the number of cells positive for doublecortin, a marker of neuronal maturation. |
2013-04-04 |
2023-08-12 |
mouse |
| Y Hu, E A Ehli, J J Hudziak, G E Davie. Berberine and evodiamine influence serotonin transporter (5-HTT) expression via the 5-HTT-linked polymorphic region. The pharmacogenomics journal. vol 12. issue 5. 2013-04-03. PMID:21647174. |
the aim of this study was to investigate the effect of berberine and evodiamine on serotonin transporter (5-htt) expression and then test how allelic variations previously identified in the promoter region could modulate that effect in the serotonergic neuronal cell line rn46a. |
2013-04-03 |
2023-08-12 |
Not clear |
| Michael H Donovan, Laurence H Tecot. Serotonin and the regulation of mammalian energy balance. Frontiers in neuroscience. vol 7. 2013-04-02. PMID:23543912. |
generally, investigation into the central serotonergic regulation of energy balance has had a predominantly "hypothalamocentric" focus, yet non-hypothalamic structures that have been implicated in energy balance regulation also receive serotonergic innervation and express multiple subtypes of serotonin receptors. |
2013-04-02 |
2023-08-12 |
Not clear |
| Jeffery Batis, Olivier Barret, David Alagille, Andrei O Koren, Jeffrey S Stehouwer, Kelly Cosgrove, Mark Goodman, John Seibyl, Gilles Tamagna. In vivo evaluation of [¹²³I]mZIENT as a SPECT radioligand for the serotonin transporter. Nuclear medicine and biology. vol 39. issue 8. 2013-03-28. PMID:23084043. |
in vivo imaging of the serotonin transporter continues to be a valuable tool in drug development and in monitoring diseases that alter serotonergic function. |
2013-03-28 |
2023-08-12 |
Not clear |
| Julie A Wixey, Hanna E Reinebrant, Kathryn M Bulle. Evidence that the serotonin transporter does not shift into the cytosol of remaining neurons after neonatal brain injury. Neuroscience research. vol 73. issue 3. 2013-03-26. PMID:22525280. |
furthermore, since concomitant reductions in 5-ht, sert and serotonergic neurons occur after neonatal hi, it is plausible that the decrease in brain 5-ht is a consequence of sert being lost as neurons degenerate as opposed to remaining neurons internalising sert or clearance by glial cells. |
2013-03-26 |
2023-08-12 |
rat |
| Leandro C Souza, Marcelo G de Gomes, André T R Goes, Lucian Del Fabbro, Carlos B Filho, Silvana P Boeira, Cristiano R Jess. Evidence for the involvement of the serotonergic 5-HT(1A) receptors in the antidepressant-like effect caused by hesperidin in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:22996046. |
evidence for the involvement of the serotonergic 5-ht(1a) receptors in the antidepressant-like effect caused by hesperidin in mice. |
2013-03-26 |
2023-08-12 |
mouse |
| Leandro C Souza, Marcelo G de Gomes, André T R Goes, Lucian Del Fabbro, Carlos B Filho, Silvana P Boeira, Cristiano R Jess. Evidence for the involvement of the serotonergic 5-HT(1A) receptors in the antidepressant-like effect caused by hesperidin in mice. Progress in neuro-psychopharmacology & biological psychiatry. vol 40. 2013-03-26. PMID:22996046. |
the antidepressant-like effect caused by hesperidin in mice in the tst was dependent on an interaction with the serotonergic 5-ht(1a) receptors. |
2013-03-26 |
2023-08-12 |
mouse |
| Jonathan P Roiser, Jamey Levy, Stephen J Fromm, David Goldman, Colin A Hodgkinson, Gregor Hasler, Barbara J Sahakian, Wayne C Drevet. Serotonin transporter genotype differentially modulates neural responses to emotional words following tryptophan depletion in patients recovered from depression and healthy volunteers. Journal of psychopharmacology (Oxford, England). vol 26. issue 11. 2013-03-18. PMID:22495688. |
previous studies have suggested that polymorphism in the serotonin transporter gene (5-httlpr) influences responses to serotonergic manipulation, with opposite effects in patients recovered from depression (rmdd) and controls. |
2013-03-18 |
2023-08-12 |
human |
| José A Larrauri, Edward D Levi. Differential effects of the antidepressant mirtazapine on amphetamine- and dizocilpine-induced PPI deficits. Pharmacology, biochemistry, and behavior. vol 102. issue 1. 2013-03-14. PMID:22469866. |
in the current study we assessed the effects of the antidepressant mirtazapine, which has combined antagonist effects at α(2)-noradrenergic, h(1)-histaminergic and 5-ht serotonergic receptors, on amphetamine- and dizocilpine-induced ppi deficits. |
2013-03-14 |
2023-08-12 |
rat |
| Mariana Freire Barbieri Gerzson, Francine N Victoria, Cátia S Radatz, Marcelo G de Gomes, Silvana P Boeira, Raquel G Jacob, Diego Alves, Cristiano Ricardo Jesse, Lucielli Savegnag. In vitro antioxidant activity and in vivo antidepressant-like effect of α-(phenylselanyl) acetophenone in mice. Pharmacology, biochemistry, and behavior. vol 102. issue 1. 2013-03-14. PMID:22484161. |
in addition, the antidepressant-like effect caused by psap (5m/kg, p.o) in mice during the tst was dependent on an interaction with the serotonergic system (5-ht(1a) receptors), but not with the noradrenergic, dopaminergic or adenosinergic system. |
2013-03-14 |
2023-08-12 |
mouse |
| Huiyi H Chang, Leif A Havto. Serotonergic 5-HT(1A) receptor agonist (8-OH-DPAT) ameliorates impaired micturition reflexes in a chronic ventral root avulsion model of incomplete cauda equina/conus medullaris injury. Experimental neurology. vol 239. 2013-02-28. PMID:23099413. |
serotonergic 5-ht(1a) receptor agonist (8-oh-dpat) ameliorates impaired micturition reflexes in a chronic ventral root avulsion model of incomplete cauda equina/conus medullaris injury. |
2013-02-28 |
2023-08-12 |
rat |
| Huiyi H Chang, Leif A Havto. Serotonergic 5-HT(1A) receptor agonist (8-OH-DPAT) ameliorates impaired micturition reflexes in a chronic ventral root avulsion model of incomplete cauda equina/conus medullaris injury. Experimental neurology. vol 239. 2013-02-28. PMID:23099413. |
we conclude that serotonergic modulation of the 5-ht(1a) receptor may represent a new strategy to improve lower urinary tract function after incomplete cauda equina/conus medullaris injuries in experimental studies. |
2013-02-28 |
2023-08-12 |
rat |
| Timothy D Tayler, Diego A Pacheco, Anne C Hergarden, Mala Murthy, David J Anderso. A neuropeptide circuit that coordinates sperm transfer and copulation duration in Drosophila. Proceedings of the National Academy of Sciences of the United States of America. vol 109. issue 50. 2013-02-28. PMID:23197833. |
crz promotes ssft by activating serotonergic (5-ht) projection neurons (pns) that innervate the accessory glands. |
2013-02-28 |
2023-08-12 |
drosophila_melanogaster |
| Li Cui, Jing-Hua Wang, Min Wang, Min Huang, Chun-Yong Wang, Huan Xia, Jian-guo Xu, Ming-Xian Li, Shao Wan. Injection of L-glutamate into the insular cortex produces sleep apnea and serotonin reduction in rats. Sleep & breathing = Schlaf & Atmung. vol 16. issue 3. 2013-02-27. PMID:21948100. |
the neuronal and cellular mechanisms underlying this process are not fully understood, although the focus of some studies is on putative serotonin (5-ht) mechanisms, and serotonergic therapy may be beneficial to osa patients. |
2013-02-27 |
2023-08-12 |
rat |
| Gilda Baccini, Boris Mlinar, Enrica Audero, Cornelius Thilo Gross, Renato Corradett. Impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1A (Htr1a) receptors. PloS one. vol 7. issue 9. 2013-02-26. PMID:23028768. |
impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1a (htr1a) receptors. |
2013-02-26 |
2023-08-12 |
mouse |
| Gilda Baccini, Boris Mlinar, Enrica Audero, Cornelius Thilo Gross, Renato Corradett. Impaired chemosensitivity of mouse dorsal raphe serotonergic neurons overexpressing serotonin 1A (Htr1a) receptors. PloS one. vol 7. issue 9. 2013-02-26. PMID:23028768. |
we recently created a transgenic mouse line in which a functional deficit in serotonin homeostasis due to excessive serotonin autoinhibition was produced by inducing serotonin 1a receptor (htr1a) overexpression selectively in serotonergic neurons (htr1a raphe-overexpressing or htr1a(ro) mice). |
2013-02-26 |
2023-08-12 |
mouse |
| Lee Fruson, Sarah Dalesman, Ken Lukowia. A flavonol present in cocoa [(-)epicatechin] enhances snail memory. The Journal of experimental biology. vol 215. issue Pt 20. 2013-02-25. PMID:23014569. |
previous work has indicated that memory-enhancing stressors (predator kairomones and kcl) act via sensory input from the osphradium and are dependent on a serotonergic (5-ht) signalling pathway. |
2013-02-25 |
2023-08-12 |
Not clear |
| Catherine E Hagan, Ross A McDevitt, Yusha Liu, Amy R Furay, John F Neumaie. 5-HT(1B) autoreceptor regulation of serotonin transporter activity in synaptosomes. Synapse (New York, N.Y.). vol 66. issue 12. 2013-02-21. PMID:22961814. |
serotonin-1b (5-ht(1b) ) autoreceptors are located in serotonin (5-ht) terminals, along with serotonin transporters (sert), and play a critical role in autoregulation of serotonergic neurotransmission and are implicated in disorders of serotonergic function, particularly emotional regulation. |
2013-02-21 |
2023-08-12 |
mouse |