| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Saobo Le. Serotonergic modulation of Neural activities in the entorhinal cortex. International journal of physiology, pathophysiology and pharmacology. vol 4. issue 4. 2013-01-16. PMID:23320133. |
the ec receives profuse serotonergic innervations from the raphe nuclei in the brainstem and expresses high density of serotonergic receptors including 5-ht(1a), 5-ht(1d), 5-ht(1e), 5-ht(2a), 5-ht(3) and 5-ht(6). |
2013-01-16 |
2023-08-12 |
Not clear |
| Saobo Le. Serotonergic modulation of Neural activities in the entorhinal cortex. International journal of physiology, pathophysiology and pharmacology. vol 4. issue 4. 2013-01-16. PMID:23320133. |
the prominent innervation by serotonergic neurons and the dense expression of serotonergic receptors in the ec suggest that serotonin is a major modulator in this brain region. |
2013-01-16 |
2023-08-12 |
Not clear |
| Gaynor A Smith, Ludivine S Breger, Emma L Lane, Stephen B Dunnet. Pharmacological modulation of amphetamine-induced dyskinesia in transplanted hemi-parkinsonian rats. Neuropharmacology. vol 63. issue 5. 2013-01-14. PMID:22722025. |
agents include: dopaminergic antagonists (d₁: cp94253; d₂: sch-22390; d₃: nafadotride), serotonergic agonists (5-ht(1a): 8-oh-dpat; 5-ht(1b): cp94253), opioid antagonist (μ: naloxone), cannabinoid agonist (cb₁: win55, 212-2), adrenergic antagonist (α₁ and α₂: yohimbine) and glutamatergic antagonists (nmda: amantadine and mk-801; mglur5: mtep; ampa: iem1460). |
2013-01-14 |
2023-08-12 |
rat |
| Lisa Pahl, Michael Bernateck, Jana Jakobi, Anh-Thu Tran, Lilly Volkmann, Dennis Buers, Ulrich Lehmann, Matthias Karst, Manfred Stuhrman. Interaction of the dopaminergic and serotonergic systems significantly influences the risk for multisomatoform disorder: a controlled pilot study. Genetic testing and molecular biomarkers. vol 16. issue 8. 2013-01-14. PMID:22784335. |
since pain is a major component of msd and dopamine as well as serotonin are involved in pain pathways, genes of the dopaminergic and serotonergic system are promising candidate genes and we assumed that polymorphisms could be associated with msd. |
2013-01-14 |
2023-08-12 |
human |
| Randy A Sansone, Lori A Sanson. SSRIs: bad to the bone? Innovations in clinical neuroscience. vol 9. issue 7-8. 2013-01-10. PMID:22984652. |
these risks may be enhanced by more serotonergic agents and/or longer exposure to selective serotonin reuptake inhibitors. |
2013-01-10 |
2023-08-12 |
Not clear |
| Henry R Kranzler, James R McKa. Personalized treatment of alcohol dependence. Current psychiatry reports. vol 14. issue 5. 2013-01-08. PMID:22810115. |
studies have also shown moderating effects of variation in the gene encoding the serotonin transporter on response to serotonergic treatment of alcohol dependence. |
2013-01-08 |
2023-08-12 |
Not clear |
| Julieta Garduño, Luis Galindo-Charles, Javier Jiménez-Rodríguez, Elvira Galarraga, Dagoberto Tapia, Stefan Mihailescu, Salvador Hernandez-Lope. Presynaptic α4β2 nicotinic acetylcholine receptors increase glutamate release and serotonin neuron excitability in the dorsal raphe nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 43. 2013-01-07. PMID:23100436. |
several behavioral effects of nicotine are mediated by changes in serotonin (5-ht) release in brain areas that receive serotonergic afferents from the dorsal raphe nucleus (drn). |
2013-01-07 |
2023-08-12 |
rat |
| Miki Yamauchi, Taiichiro Imanishi, Tsukasa Koyam. A combination of mirtazapine and milnacipran augments the extracellular levels of monoamines in the rat brain. Neuropharmacology. vol 62. issue 7. 2012-12-20. PMID:22342987. |
these results suggest that combined treatment with mirtazapine and milnacipran augments the extracellular levels of noradrenaline, serotonin and dopamine through the blockade of α(2) adrenoceptors without regional specificity, whereas mirtazapine enhances serotonergic transmission in a region-specific manner. |
2012-12-20 |
2023-08-12 |
rat |
| François Giuliano, Pierre Clèmen. Pharmacology for the treatment of premature ejaculation. Pharmacological reviews. vol 64. issue 3. 2012-12-17. PMID:22679220. |
ejaculation is centrally mediated by a variety of neurotransmitter systems, involving especially serotonin and serotonergic pathways but also dopaminergic and oxytocinergic systems. |
2012-12-17 |
2023-08-12 |
Not clear |
| Divya Sitaraman, Holly LaFerriere, Serge Birman, Troy Zar. Serotonin is critical for rewarded olfactory short-term memory in Drosophila. Journal of neurogenetics. vol 26. issue 2. 2012-12-07. PMID:22436011. |
by targeting the tetanus toxin light chain (tnt) and the human inwardly rectifying potassium channel (kir2.1) to the serotonin neurons with two different gal4 driver combinations, the serotonergic system was inhibited. |
2012-12-07 |
2023-08-12 |
human |
| Susana Esteban, Jesús A García-Sevill. Effects induced by cannabinoids on monoaminergic systems in the brain and their implications for psychiatric disorders. Progress in neuro-psychopharmacology & biological psychiatry. vol 38. issue 1. 2012-12-03. PMID:22133541. |
in general, the acute stimulation of cb(1) receptors increases the activity (spontaneous firing rate) of noradrenergic (ne), serotonergic (5-ht) and dopaminergic (da) neurons as well as the synthesis and/or release of the corresponding neurotransmitter in specific brain regions. |
2012-12-03 |
2023-08-12 |
Not clear |
| Diana L Price, Douglas W Bonhaus, Krista McFarlan. Pimavanserin, a 5-HT2A receptor inverse agonist, reverses psychosis-like behaviors in a rodent model of Alzheimer's disease. Behavioural pharmacology. vol 23. issue 4. 2012-12-03. PMID:22750845. |
these data suggest that an infusion of amyloid β might induce alterations in serotonergic function that underlie a psychosis-like phenotype that can be normalized by treatment with a 5-ht(2a) inverse agonist. |
2012-12-03 |
2023-08-12 |
mouse |
| Andreas Husch, Gabrielle N Van Patten, Diana N Hong, Moira M Scaperotti, Nathan Cramer, Ronald M Harris-Warric. Spinal cord injury induces serotonin supersensitivity without increasing intrinsic excitability of mouse V2a interneurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 38. 2012-12-03. PMID:22993431. |
immunocytochemical analysis showed that sci caused a coordinated loss of serotonergic fibers and the 5-ht transporter (sert). |
2012-12-03 |
2023-08-12 |
mouse |
| Shikha Gupta, Vinay Kumar Khanna, Anupam Maurya, Dnyaneshwar Umrao Bawankule, Rajendra Kumar Shukla, Anirban Pal, Santosh Kumar Srivastav. Bioactivity guided isolation of antipsychotic constituents from the leaves of Rauwolfia tetraphylla L. Fitoterapia. vol 83. issue 6. 2012-11-29. PMID:22579842. |
among the meoh extract and some alkaloidal fractions at different phs, the alkaloidal chcl(3) fraction at ph-9 (2c) showed the highest antipsychotic activity against dopaminergic (da-d(2)) and serotonergic (5-ht(2a)) receptors in-vitro and amphetamine induced hyperactive mouse model in-vivo. |
2012-11-29 |
2023-08-12 |
mouse |
| Lucía Zubizarreta, Rossana Perrone, Philip K Stoddard, Gustavo Costa, Ana C Silv. Differential serotonergic modulation of two types of aggression in weakly electric fish. Frontiers in behavioral neuroscience. vol 6. 2012-11-28. PMID:23181014. |
we found that in the reproduction-related aggression displayed by b. gauderio after conflict resolution, the serotonergic activity follows the classic pattern in which subordinates exhibit higher 5-ht levels than controls. |
2012-11-28 |
2023-08-12 |
Not clear |
| Lucía Zubizarreta, Rossana Perrone, Philip K Stoddard, Gustavo Costa, Ana C Silv. Differential serotonergic modulation of two types of aggression in weakly electric fish. Frontiers in behavioral neuroscience. vol 6. 2012-11-28. PMID:23181014. |
after the territorial aggression displayed by g. omarorum, however, both dominants and subordinates show lower 5-ht levels than controls, indicating a different response of the serotonergic system. |
2012-11-28 |
2023-08-12 |
Not clear |
| Shannon P Gerry, Amanda J Daigle, Kara L Feilich, Jessica Liao, Azzara L Oston, David J Ellerb. Serotonin as an integrator of leech behavior and muscle mechanical performance. Zoology (Jena, Germany). vol 115. issue 4. 2012-11-27. PMID:22722077. |
although 5-ht can enhance muscle mechanical performance during simulated feeding, low in vivo activity in serotonergic neurons during feeding may mean that its mechanical role during this behavior is less important than during locomotion. |
2012-11-27 |
2023-08-12 |
Not clear |
| Małgorzata Wrzosek, Andrzej Jakubczyk, Michał Wrzosek, Halina Matsumoto, Jacek Łukaszkiewicz, Kirk J Brower, Marcin Wojna. Serotonin 2A receptor gene (HTR2A) polymorphism in alcohol-dependent patients. Pharmacological reports : PR. vol 64. issue 2. 2012-11-23. PMID:22661198. |
the serotonergic (5-ht) dysfunction has been frequently described in subjects with alcohol dependence (ad). |
2012-11-23 |
2023-08-12 |
human |
| A Mickle, P Kannampalli, M Bruckert, A Miranda, B Banerjee, J N Sengupt. Pronociceptive effect of 5-HT(1A) receptor agonist on visceral pain involves spinal N-methyl-D-aspartate (NMDA) receptor. Neuroscience. vol 219. 2012-11-20. PMID:22626644. |
the functional role of serotonergic 5-ht(1a) receptors in the modulation of visceral pain is controversial. |
2012-11-20 |
2023-08-12 |
rat |
| Nishaki Kiran Mehta, Gerard Aurigemma, Zahi Rafeq, Oscar Starobi. Reverse takotsubo cardiomyopathy: after an episode of serotonin syndrome. Texas Heart Institute journal. vol 38. issue 5. 2012-11-13. PMID:22163138. |
serotonin syndrome is best understood as excess serotonergic activity in the central and peripheral nervous system. |
2012-11-13 |
2023-08-12 |
Not clear |