| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elodie Bouaziz, Michel Boris Emerit, Guilan Vodjdani, Vanessa Gautheron, Michel Hamon, Michèle Darmon, Justine Masso. Neuronal phenotype dependency of agonist-induced internalization of the 5-HT(1A) serotonin receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381289. |
acute exposure (for 1 h) to the full 5-ht(1a)r agonists, 5-ht and 5-carboxamido-tryptamine, but not the partial agonist 8-oh-dpat, triggered internalization of tagged 5-ht(1a)r in serotonergic neurons only. |
2014-02-24 |
2023-08-12 |
rat |
| Elodie Bouaziz, Michel Boris Emerit, Guilan Vodjdani, Vanessa Gautheron, Michel Hamon, Michèle Darmon, Justine Masso. Neuronal phenotype dependency of agonist-induced internalization of the 5-HT(1A) serotonin receptor. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 1. 2014-02-24. PMID:24381289. |
its differential occurrence in serotonergic neurons supports the idea that 5-ht(1a)r internalization might underlie 5-ht(1a) autoreceptor desensitization under ssri antidepressant therapy. |
2014-02-24 |
2023-08-12 |
rat |
| James H Fox, Christopher A Lowr. Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior. Frontiers in neuroscience. vol 7. 2014-02-18. PMID:24065880. |
crf and crf-related peptides act within the dorsal raphe nucleus (dr), the major source for serotonin (5-ht) in the brain, to alter the neuronal activity of specific subsets of serotonergic neurons and to influence stress-related behavior. |
2014-02-18 |
2023-08-12 |
Not clear |
| James H Fox, Christopher A Lowr. Corticotropin-releasing factor-related peptides, serotonergic systems, and emotional behavior. Frontiers in neuroscience. vol 7. 2014-02-18. PMID:24065880. |
crf and crf-related peptides can either increase or decrease serotonergic neuronal firing rates and serotonin release, depending on their concentrations and on the specific crf receptor subtype(s) involved. |
2014-02-18 |
2023-08-12 |
Not clear |
| Rafaela Quintanilha Abrahão, Adriano Cardoso Franciosi, Douglas Andrade, Luiz Juliano, Maria Aparecida Juliano, Renata Giorgi, Camila Squarzoni Dal. Oligopeptidases B from Trypanossoma cruzi and Trypanossoma brucei inhibit inflammatory pain in mice by targeting serotoninergic receptors. Inflammation. vol 36. issue 3. 2014-02-13. PMID:23377962. |
intraperitoneal pretreatment with methysergide (5-ht serotonergic receptor antagonist) attenuated antinociceptive effect induced by both optc and optb in the writhing test. |
2014-02-13 |
2023-08-12 |
mouse |
| Ul'yana A Boyarskikh, Natalya P Bondar, Maxim L Filipenko, Natalia N Kudryavtsev. Downregulation of serotonergic gene expression in the Raphe nuclei of the midbrain under chronic social defeat stress in male mice. Molecular neurobiology. vol 48. issue 1. 2014-02-12. PMID:23392607. |
csds experience inducing the development of mixed anxiety/depression-like state in male mice downregulates the expression of serotonergic genes associated with the synthesis, inactivation, and reception of serotonin. |
2014-02-12 |
2023-08-12 |
mouse |
| Winanda W Ursinus, J Elizabeth Bolhuis, Johan J Zonderland, T Bas Rodenburg, Adriana S de Souza, Rudie E Koopmanschap, Bas Kemp, Gerdien A H Korte-Bouws, S Mechiel Korte, Cornelis G van Reene. Relations between peripheral and brain serotonin measures and behavioural responses in a novelty test in pigs. Physiology & behavior. vol 118. 2014-02-12. PMID:23685231. |
platelet serotonin level and brain serotonergic parameters in the hippocampus were interrelated. |
2014-02-12 |
2023-08-12 |
Not clear |
| Magdalena Nord, Sjoerd J Finnema, Christer Halldin, Lars Fard. Effect of a single dose of escitalopram on serotonin concentration in the non-human and human primate brain. The international journal of neuropsychopharmacology. vol 16. issue 7. 2014-02-10. PMID:23351590. |
to assess whether a single dose of the ssri escitalopram affects endogenous serotonin concentrations in serotonergic projection areas and in the raphe nuclei (rn), three cynomolgus monkeys and nine human subjects underwent pet examinations with [¹¹c]az10419369 at baseline conditions and after escitalopram administration. |
2014-02-10 |
2023-08-12 |
human |
| Magdalena Nord, Sjoerd J Finnema, Christer Halldin, Lars Fard. Effect of a single dose of escitalopram on serotonin concentration in the non-human and human primate brain. The international journal of neuropsychopharmacology. vol 16. issue 7. 2014-02-10. PMID:23351590. |
in the present study, a single, clinically relevant, dose of escitalopram was found to decrease serotonin concentrations in serotonergic projection areas in humans. |
2014-02-10 |
2023-08-12 |
human |
| Magdalena Nord, Sjoerd J Finnema, Christer Halldin, Lars Fard. Effect of a single dose of escitalopram on serotonin concentration in the non-human and human primate brain. The international journal of neuropsychopharmacology. vol 16. issue 7. 2014-02-10. PMID:23351590. |
hypothetically, desensitization of inhibitory serotonergic autoreceptors will cause the serotonin concentration in projection areas to increase over time with chronic administration. |
2014-02-10 |
2023-08-12 |
human |
| Yvonne Dempsie, Neil A MacRitchie, Kevin White, Ian Morecroft, Audrey F Wright, Margaret Nilsen, Lynn Loughlin, Kirsty M Mair, Margaret R MacLea. Dexfenfluramine and the oestrogen-metabolizing enzyme CYP1B1 in the development of pulmonary arterial hypertension. Cardiovascular research. vol 99. issue 1. 2014-01-31. PMID:23519266. |
dfen mediates pah via a serotonergic mechanism and we have shown serotonin to up-regulate expression of cyp1b1 in human pulmonary artery smooth muscle cells (pasmcs). |
2014-01-31 |
2023-08-12 |
human |
| Jeffrey M Miller, Natalie Hesselgrave, R Todd Ogden, Gregory M Sullivan, Maria A Oquendo, J John Mann, Ramin V Parse. Positron emission tomography quantification of serotonin transporter in suicide attempters with major depressive disorder. Biological psychiatry. vol 74. issue 4. 2014-01-30. PMID:23453288. |
several lines of evidence implicate abnormal serotonergic function in suicidal behavior and completed suicide, including low serotonin transporter binding in postmortem studies of completed suicide. |
2014-01-30 |
2023-08-12 |
Not clear |
| Jean-François Perrier, Hanne Borger Rasmussen, Rasmus Kordt Christensen, Anders Victor Peterse. Modulation of the intrinsic properties of motoneurons by serotonin. Current pharmaceutical design. vol 19. issue 24. 2014-01-27. PMID:23360270. |
under pathological conditions, such as after a spinal cord injury, the promotion of persistent inward currents by serotonin and/or the overexpression of autoactive serotonergic receptors may contribute to motoneuronal excitability, muscle spasms and spasticity and hence, impairment of stereotyped motor behaviors such as locomotion, ejaculation and micturition. |
2014-01-27 |
2023-08-12 |
Not clear |
| Tara Deemyad, Michael G Metzen, Yingzhou Pan, Maurice J Chacro. Serotonin selectively enhances perception and sensory neural responses to stimuli generated by same-sex conspecifics. Proceedings of the National Academy of Sciences of the United States of America. vol 110. issue 48. 2014-01-27. PMID:24218585. |
here we examined the functional role of serotonergic innervation onto electrosensory neurons in weakly electric fish by eliciting endogenous release through electrical stimulation as well as exogenous focal application of serotonin in the vicinity of the cell being recorded from. |
2014-01-27 |
2023-08-12 |
Not clear |
| Chaoran Ren, Liju Luan, Benson Wui-Man Lau, Xin Huang, Jian Yang, Yuan Zhou, Xihong Wu, Jie Gao, Gary E Pickard, Kwok-Fai So, Mingliang P. Direct retino-raphe projection alters serotonergic tone and affective behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 7. 2014-01-24. PMID:23370156. |
we found that light deprivation produces a depressive-like behavioral state that is reversed by activation of direct retinal signals to the serotonergic dorsal raphe nucleus (drn) in a manner equivalent to treatment with the selective serotonin reuptake inhibitor fluoxetine. |
2014-01-24 |
2023-08-12 |
Not clear |
| Chaoran Ren, Liju Luan, Benson Wui-Man Lau, Xin Huang, Jian Yang, Yuan Zhou, Xihong Wu, Jie Gao, Gary E Pickard, Kwok-Fai So, Mingliang P. Direct retino-raphe projection alters serotonergic tone and affective behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 7. 2014-01-24. PMID:23370156. |
serotonin has a key role in the pathophysiology of depression, and these results demonstrate that retino-raphe signals modulate drn serotonergic tone and affective behavior. |
2014-01-24 |
2023-08-12 |
Not clear |
| Kohji Sat. Disruption of spine homeostasis causes depression. Medical hypotheses. vol 81. issue 1. 2014-01-15. PMID:23631853. |
on the other hand, general serotonin vulnerability has been also proposed as a major risk factor in depression, where the paucity of available serotonin is involved in the pathogenesis of depression, indicating that the serotonergic system somehow possesses the ability to regulate spine homeostasis. |
2014-01-15 |
2023-08-12 |
human |
| Caio Maximino, Bruna Puty, Rancés Benzecry, Juliana Araújo, Monica Gomes Lima, Evander de Jesus Oliveira Batista, Karen Renata de Matos Oliveira, Maria Elena Crespo-Lopez, Anderson Manoel Herculan. Role of serotonin in zebrafish (Danio rerio) anxiety: relationship with serotonin levels and effect of buspirone, WAY 100635, SB 224289, fluoxetine and para-chlorophenylalanine (pCPA) in two behavioral models. Neuropharmacology. vol 71. 2014-01-10. PMID:23541719. |
these results underline the differential sensitivity of these tasks to assess serotonergic agents; alternatively, serotonin might regulate zebrafish behavior differently in the novel tank test and in the light/dark test. |
2014-01-10 |
2023-08-12 |
zebrafish |
| Soo-Hyun Park, Yun-Beom Sim, Yu-Jung Kang, Sung-Su Kim, Chea-Ha Kim, Su-Jin Kim, Su-Min Lim, Hong-Won Su. Antinociceptive profiles and mechanisms of orally administered coumarin in mice. Biological & pharmaceutical bulletin. vol 36. issue 6. 2014-01-07. PMID:23727914. |
however, methysergide (a 5-ht serotonergic receptor antagonist) or yohimbine (an α2-adrenergic receptor antagonist) did not affect antinociception induced by coumarin in the writhing test. |
2014-01-07 |
2023-08-12 |
mouse |
| Martina Böttner, Martina Barrenschee, Ines Hellwig, Jonas Harde, Jan-Hendrik Egberts, Thomas Becker, Dimitri Zorenkov, Thilo Wede. The enteric serotonergic system is altered in patients with diverticular disease. Gut. vol 62. issue 12. 2014-01-06. PMID:23144076. |
gene expression profiles of the serotonergic system and distribution of the serotonin type 4 receptor (5ht-4r) were thus studied in patients with dd. |
2014-01-06 |
2023-08-12 |
Not clear |