| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H O Kalkman, G Engel, D Hoye. Three distinct subtypes of serotonergic receptors mediate the triphasic blood pressure response to serotonin in rats. Journal of hypertension. Supplement : official journal of the International Society of Hypertension. vol 2. issue 3. 1986-06-25. PMID:6599662. |
three distinct subtypes of serotonergic receptors mediate the triphasic blood pressure response to serotonin in rats. |
1986-06-25 |
2023-08-12 |
rat |
| R A Cohe. Contractions of isolated canine coronary arteries resistant to S2-serotonergic blockade. The Journal of pharmacology and experimental therapeutics. vol 237. issue 2. 1986-06-23. PMID:2939235. |
the purpose of this study was to compare the effect of two serotonergic receptor antagonists on the contractile responses mediated by 5-hydroxytryptamine (5-ht) in isolated canine coronary arteries. |
1986-06-23 |
2023-08-11 |
Not clear |
| J A Severson, J J Woodward, R E Wilco. Subdivision of mouse brain [3H]imipramine binding based on ion dependence and serotonin sensitivity. Journal of neurochemistry. vol 46. issue 6. 1986-06-20. PMID:3701330. |
thus, the binding of [3h]imipramine that is displaced by desipramine, the most common assay for [3h]imipramine binding, includes a component that is not associated with brain serotonergic nerve terminals and 5-ht uptake, and, in addition, a separable component that is highly correlated with serotonergic function. |
1986-06-20 |
2023-08-11 |
mouse |
| A S Eison, M S Eison, M Stanley, L A Rible. Serotonergic mechanisms in the behavioral effects of buspirone and gepirone. Pharmacology, biochemistry, and behavior. vol 24. issue 3. 1986-06-17. PMID:2871564. |
serotonergic involvement in the mechanism of action of two nonbenzodiazepine anxiolytics, buspirone and gepirone, supports a role for serotonin in anxiety. |
1986-06-17 |
2023-08-11 |
rat |
| A S Eison, M S Eison, M Stanley, L A Rible. Serotonergic mechanisms in the behavioral effects of buspirone and gepirone. Pharmacology, biochemistry, and behavior. vol 24. issue 3. 1986-06-17. PMID:2871564. |
while other components of buspirone's mechanism of action may suppress the behavioral expression of its serotonergic interactions, results from these studies suggest that serotonin agonist-like activity may be an important mechanism in the actions of a clinically proven nonbenzodiazepine anxiolytic (buspirone), and anxiolytic candidate (gepirone). |
1986-06-17 |
2023-08-11 |
rat |
| K Rasmussen, R E Strecker, B L Jacob. Single unit response of noradrenergic, serotonergic and dopaminergic neurons in freely moving cats to simple sensory stimuli. Brain research. vol 369. issue 1-2. 1986-06-13. PMID:3697750. |
the response of noradrenergic (ne), serotonergic (5-ht), and dopaminergic (da), neurons to repeated presentations (once/2 s for 64 trials) of phasic auditory (click) and visual (flash) stimuli was examined in freely moving cats. |
1986-06-13 |
2023-08-11 |
Not clear |
| A I Barka. Interactions of drugs and electroshock treatment on cerebral monoaminergic systems. Annals of the New York Academy of Sciences. vol 462. 1986-06-11. PMID:2423001. |
similarly, the effect of hldl on 5ht turnover and the antagonistic interaction of est on this hldl-induced effect were associated with changes in 3h-imi binding sites that label the 5ht transporter in serotonergic presynaptic terminals. |
1986-06-11 |
2023-08-11 |
Not clear |
| P J Monroe, K Michaux, D J Smit. Evaluation of the direct actions of drugs with a serotonergic link in spinal analgesia on the release of [3H]serotonin from spinal cord synaptosomes. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3517671. |
evaluation of the direct actions of drugs with a serotonergic link in spinal analgesia on the release of [3h]serotonin from spinal cord synaptosomes. |
1986-06-06 |
2023-08-11 |
rat |
| P J Monroe, K Michaux, D J Smit. Evaluation of the direct actions of drugs with a serotonergic link in spinal analgesia on the release of [3H]serotonin from spinal cord synaptosomes. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3517671. |
morphine, ketamine, ethylketocyclazocine and quipazine, drugs with an apparent local spinal serotonergic action, which contributes to their analgesic effects, were tested for their ability to alter the release of [3h]serotonin ([3h]5-ht) from a synaptosomal preparation from the spinal cord of the rat. |
1986-06-06 |
2023-08-11 |
rat |
| P J Monroe, K Michaux, D J Smit. Evaluation of the direct actions of drugs with a serotonergic link in spinal analgesia on the release of [3H]serotonin from spinal cord synaptosomes. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3517671. |
however, quipazine inhibited the depressant action of exogenous 5-ht on overflow of 3h (mediated through the 5-ht autoreceptor), an action that should facilitate serotonergic neurotransmission. |
1986-06-06 |
2023-08-11 |
rat |
| J R Holtman, T E Dick, A J Berge. Involvement of serotonin in the excitation of phrenic motoneurons evoked by stimulation of the raphe obscurus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 4. 1986-06-06. PMID:3701414. |
the early response does not involve serotonin release, while the later response is mediated at least in part by activation of a serotonergic pathway. |
1986-06-06 |
2023-08-11 |
Not clear |
| G N Galanina, I S Zakharov, O A Maksimova, P M Balaba. [Role of the giant serotonin-containing cell of the cerebral ganglion in the edible snail in organizing its food-acquiring behavior]. Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova. vol 36. issue 1. 1986-06-06. PMID:3705747. |
by adding dopamine or serotonin to a bath with snail's isolated nervous system and by intracellular activation of giant cerebral serotonergic cells it was established in neurophysiological experiments that, in spite of activating effect of serotonin on buccal motorneurones, dopamine is the transmitter triggering feeding movements of the buccal mass and feeding pattern in buccal motorneurones. |
1986-06-06 |
2023-08-11 |
Not clear |
| J S Han, Y T Xua. A mesolimbic neuronal loop of analgesia: I. Activation by morphine of a serotonergic pathway from periaqueductal gray to nucleus accumbens. The International journal of neuroscience. vol 29. issue 1-2. 1986-05-27. PMID:3486166. |
the results suggest that morphine acting on pag seems to activate an ascending serotonergic pathway and, by releasing 5-ht in nucleus accumbens, to exert an analgesic effect. |
1986-05-27 |
2023-08-11 |
Not clear |
| S Candeletti, P Romualdi, C Spadaro, S Spampinato, S Ferr. Studies on the antinociceptive effect of intrathecal salmon calcitonin. Peptides. vol 6 Suppl 3. 1986-05-15. PMID:3008120. |
a delay in the development of it sct-induced antinociception was observed in rats selectively depleted of cord serotonin (25 mg/kg ip desipramine plus 100 micrograms it 5,7-dihydroxytryptamine), whereas the administration of serotonergic antagonists, methysergide and ketanserin, 30 micrograms it, did not influence sct effect. |
1986-05-15 |
2023-08-11 |
rat |
| R W Fulle. Pharmacologic modification of serotonergic function: drugs for the study and treatment of psychiatric and other disorders. The Journal of clinical psychiatry. vol 47 Suppl. 1986-05-14. PMID:3514585. |
the development of direct serotonin agonists, selective inhibitors of serotonin uptake, serotonin receptor antagonists, and other drugs affecting serotonergic function has aided the study of physiologic functions of brain serotonin neurons in laboratory animals and the recognition and classification of serotonin receptor subtypes. |
1986-05-14 |
2023-08-11 |
Not clear |
| D L Murphy, E A Mueller, N A Garrick, C S Aulak. Use of serotonergic agents in the clinical assessment of central serotonin function. The Journal of clinical psychiatry. vol 47 Suppl. 1986-05-14. PMID:3514586. |
use of serotonergic agents in the clinical assessment of central serotonin function. |
1986-05-14 |
2023-08-11 |
Not clear |
| D L Murphy, E A Mueller, N A Garrick, C S Aulak. Use of serotonergic agents in the clinical assessment of central serotonin function. The Journal of clinical psychiatry. vol 47 Suppl. 1986-05-14. PMID:3514586. |
to assess the status of the brain serotonergic system in relation to ongoing behavior, agents with predominant actions on serotonin synthesis, release, uptake, and receptor mechanisms are being evaluated. |
1986-05-14 |
2023-08-11 |
Not clear |
| N H Majeed, W Lasoń, B Przewłocka, R Przewłock. Serotonergic regulation of the brain and gut beta-endorphin and dynorphin content in the rat. Polish journal of pharmacology and pharmacy. vol 37. issue 6. 1986-05-06. PMID:2870487. |
the obtained results suggest that serotonergic activation stimulates the release of beta-endorphin from the anterior pituitary and dynorphin from the gut, while the cerebral beta-endorphin system appears to be inhibited by activation of serotonin neurons. |
1986-05-06 |
2023-08-11 |
rat |
| S O Ogre. Serotonin receptor involvement in the avoidance learning deficit caused by p-chloroamphetamine-induced serotonin release. Acta physiologica Scandinavica. vol 126. issue 3. 1986-04-30. PMID:2870606. |
the avoidance deficit was blocked at low doses by serotonergic (5-ht)-receptor blocking agents but not by alpha-adrenergic-, beta-adrenergic-, opiate-, muscarinic- or dopamine d2-receptor antagonists. |
1986-04-30 |
2023-08-11 |
rat |
| A Mori, M Hiramatsu, H Kabuto, B Maresca. Effects of emotional stress on E1-mouse convulsions, and their biochemical background. Neurochemical research. vol 11. issue 1. 1986-04-28. PMID:2421176. |
these findings suggest that the serotonergic system is involved in the inhibition of e1 mouse convulsions, through an enhanced serotonin release in the brain brought on by the emotional stress. |
1986-04-28 |
2023-08-11 |
mouse |