| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Fagervall, S B Ros. A and B forms of monoamine oxidase within the monoaminergic neurons of the rat brain. Journal of neurochemistry. vol 47. issue 2. 1986-09-17. PMID:3734795. |
results with the two inhibitors revealed that the a and b forms were responsible for 80 and 20%, respectively, of the deamination of [14c]5-ht within serotonergic synaptosomes from the hypothalamus. |
1986-09-17 |
2023-08-11 |
rat |
| C Szostak, A Jakubovic, A G Phillips, H C Fibige. Bilateral augmentation of dopaminergic and serotonergic activity in the striatum and nucleus accumbens induced by conditioned circling. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 7. 1986-09-17. PMID:3734874. |
the involvement of dopaminergic (da) and serotonergic (5-ht) systems in circling was assessed by determining the neurochemical correlates of circling induced and maintained by two different schedules of water reinforcement. |
1986-09-17 |
2023-08-11 |
rat |
| N Limberger, G Bonanno, L Späth, K Stark. Autoreceptors and alpha 2-adrenoceptors at the serotonergic axons of rabbit brain cortex. Naunyn-Schmiedeberg's archives of pharmacology. vol 332. issue 4. 1986-09-16. PMID:2874499. |
it is concluded that the serotonergic axons of the rabbit occipitoparietal cortex possess presynaptic, release-inhibiting serotonin autoreceptors and alpha 2-adrenoceptors. |
1986-09-16 |
2023-08-11 |
rabbit |
| L D Van de Kar, K D Richardson-Morto. Serotonergic regulation of the release of renin is not mediated by the autonomic nervous system but involves beta adrenoceptors. Neuropharmacology. vol 25. issue 5. 1986-09-16. PMID:2874518. |
p-chloroamphetamine (pca) which releases serotonin is known to increase the activity of plasma renin in conscious rats by stimulating serotonergic neurotransmission in the brain. |
1986-09-16 |
2023-08-11 |
rat |
| S K Bhattachary. The antinociceptive effect of intracerebroventricularly administered prostaglandin D2 in the rat. Psychopharmacology. vol 89. issue 1. 1986-09-16. PMID:3016786. |
the antinociceptive action of centrally-administered pgd2 was markedly attenuated after pretreatment of the rats with 5,6-dihydroxytryptamine, a selective neurotoxin for central serotonergic neurones, and p-chlorophenylalanine, a specific inhibitor of serotonin synthesis, indicating that the pgd2 action is serotonin-mediated. |
1986-09-16 |
2023-08-11 |
rat |
| P M Whitaker-Azmitia, E C Azmiti. Autoregulation of fetal serotonergic neuronal development: role of high affinity serotonin receptors. Neuroscience letters. vol 67. issue 3. 1986-09-16. PMID:3461314. |
autoregulation of fetal serotonergic neuronal development: role of high affinity serotonin receptors. |
1986-09-16 |
2023-08-11 |
rat |
| P M Whitaker-Azmitia, E C Azmiti. Autoregulation of fetal serotonergic neuronal development: role of high affinity serotonin receptors. Neuroscience letters. vol 67. issue 3. 1986-09-16. PMID:3461314. |
pargyline (a non-specific monoamine oxidase inhibitor) alone and with serotonin (10(-8) to 10(-6) m) both inhibited growth of serotonergic neurons as assessed by uptake of [3h]serotonin. |
1986-09-16 |
2023-08-11 |
rat |
| R W Fuller, K D Kurz, N R Mason, M L Cohe. Antagonism of a peripheral vascular but not an apparently central serotonergic response by xylamidine and BW 501C67. European journal of pharmacology. vol 125. issue 1. 1986-09-16. PMID:3732393. |
since xylamidine and bw501c67 were potent antagonists of a peripheral serotonergic response in vivo, their inability to antagonize the elevation of serum corticosterone concentration by quipazine suggests that this effect results from activation of central serotonin receptors. |
1986-09-16 |
2023-08-11 |
rat |
| A L Johnston, S E Fil. 5-HT and anxiety: promises and pitfalls. Pharmacology, biochemistry, and behavior. vol 24. issue 5. 1986-08-04. PMID:2873592. |
the effects of manipulations of 5-ht, including 5-ht lesions, pharmacological reduction and enhancement of serotonergic function in animal tests of anxiety are reviewed. |
1986-08-04 |
2023-08-11 |
Not clear |
| M H Thiebo. Are serotonergic neurons involved in the control of anxiety and in the anxiolytic activity of benzodiazepines? Pharmacology, biochemistry, and behavior. vol 24. issue 5. 1986-08-04. PMID:2873593. |
several studies have shown that, like benzodiazepines (bzp), treatments able to reduce or block the activity of cns serotonergic (5-ht) neurons released punished behavior. |
1986-08-04 |
2023-08-11 |
rat |
| M E Otero Losada, M C Rubi. Time-related response of central serotonergic function to lithium administration. General pharmacology. vol 17. issue 3. 1986-07-25. PMID:2424806. |
the possibility of "acute" (1 hr) changes in serotonergic function by lithium chloride (licl) administration was investigated in the rat corpus striatum and frontal cerebral cortex: an increase in 5-ht biosynthesis in vivo and 5-hiaa levels was observed in both areas. |
1986-07-25 |
2023-08-11 |
rat |
| K Kuniyoshi, T Kushiro, N Kajiwar. [The role of the sympathetic nervous system and adrenals in hemodynamic changes after intracerebroventricular administration of 5-hydroxytryptamine in rats]. Nihon Naibunpi Gakkai zasshi. vol 62. issue 3. 1986-07-24. PMID:3086142. |
however, the effects of 5-hydroxytryptamine (5-ht) administration on hemodynamics have been notoriously inconsistent and the precise mechanism of the blood pressure regulation of the serotonergic nervous system has not been elucidated yet. |
1986-07-24 |
2023-08-11 |
rat |
| E M Sternberg, J Trial, C W Parke. Effect of serotonin on murine macrophages: suppression of Ia expression by serotonin and its reversal by 5-HT2 serotonergic receptor antagonists. Journal of immunology (Baltimore, Md. : 1950). vol 137. issue 1. 1986-07-18. PMID:2423604. |
effect of serotonin on murine macrophages: suppression of ia expression by serotonin and its reversal by 5-ht2 serotonergic receptor antagonists. |
1986-07-18 |
2023-08-11 |
mouse |
| D L Glanzman, F B Krasn. 5,7-Dihydroxytryptamine lesions of crayfish serotonin-containing neurons: effect on the lateral giant escape reaction. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 6. issue 6. 1986-07-18. PMID:3711995. |
to test this possibility, we attempted to lesion serotonergic neurons in crayfish with the 5-ht neurotoxin, 5,7-dihydroxytryptamine (5,7-dht). |
1986-07-18 |
2023-08-11 |
Not clear |
| P Blier, C De Montigny, A J Azzar. Modification of serotonergic and noradrenergic neurotransmissions by repeated administration of monoamine oxidase inhibitors: electrophysiological studies in the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 237. issue 3. 1986-07-16. PMID:2423685. |
the net effect of repeated administration of monoamine oxidase inhibitors (maoi) on central serotonergic (5-ht) and noradrenergic (ne) neurotransmissions was studied by assessing the responsiveness of hippocampal pyramidal neurons to microiontophoretically applied 5-ht and ne and the response of these neurons to the electrical activation of the 5-ht and ne ascending pathways. |
1986-07-16 |
2023-08-11 |
rat |
| S J Peroutka, S Huang, G S Alle. Canine basilar artery contractions mediated by 5-hydroxytryptamine1A receptors. The Journal of pharmacology and experimental therapeutics. vol 237. issue 3. 1986-07-16. PMID:2940360. |
drug interactions were also analyzed with canine basilar artery segments using 5-ht, 10 putative serotonergic agonists and a selective 5-ht2 antagonist, pirenperone. |
1986-07-16 |
2023-08-11 |
rat |
| P J Fletcher, M J Burto. Microstructural analysis of the anorectic action of peripherally administered 5-HT. Pharmacology, biochemistry, and behavior. vol 24. issue 4. 1986-07-07. PMID:3714770. |
the results are discussed in terms of a possible role for peripheral 5-ht in the control of satiety, and implications for the mode of action of serotonergic anorectic agents such as fenfluramine. |
1986-07-07 |
2023-08-11 |
rat |
| C L Melchior, B Tabakof. The effect of 5,7-dihydroxytryptamine treatment on the response to ethanol in mice. Pharmacology, biochemistry, and behavior. vol 24. issue 4. 1986-07-07. PMID:3714786. |
in order to assess the role of the serotonergic system in the development of tolerance to ethanol in the mouse, serotonin neurons in the cns were lesioned with an intracerebroventricular injection of the neurotoxin, 5,7-dihydroxytryptamine (5,7-dht). |
1986-07-07 |
2023-08-11 |
mouse |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
the neuroanatomical site of the inhibitory influence of anxiolytics on central serotonergic transmission has been investigated in the rat by studying the effect of systemic or intracerebral administration of these drugs on cerebral serotonin (5-ht) synthesis. |
1986-06-30 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Neuroanatomical site of the inhibitory influence of anxiolytic drugs on central serotonergic transmission. Brain research. vol 371. issue 1. 1986-06-30. PMID:2871894. |
local infusion of diazepam (15 micrograms) of flurazepam (1.5 micrograms) into the hippocampus of conscious rats (via indwelling cannulae) markedly reduced 5-ht synthesis in this brain area whereas infusion of these drugs into the raphé medianus (origin of the serotonergic afferents to the hippocampus) failed to affect hippocampal 5-ht synthesis. |
1986-06-30 |
2023-08-11 |
rat |