| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Tinajero, A Fabbri, M L Dufa. Serotonergic inhibition of rat Leydig cell function by propranolol. Endocrinology. vol 133. issue 1. 1993-08-03. PMID:8391422. |
the serotonergic actions of propranolol were prevented by doi, an inhibitor of 5ht actions at the high affinity site. |
1993-08-03 |
2023-08-12 |
rat |
| P Yavari, G W Vogel, D B Neil. Decreased raphe unit activity in a rat model of endogenous depression. Brain research. vol 611. issue 1. 1993-07-29. PMID:8390911. |
one theory about the pathogenesis of endogenous depression is that decreased serotonergic (5-ht) neurotransmission is involved in producing the disorder. |
1993-07-29 |
2023-08-12 |
human |
| M Koulu, U Pesonen, S Koskinen, H Scheinin, R Virtanen, M Scheini. Reduced turnover of dopamine and 5-hydroxytryptamine in discrete dopaminergic, noradrenergic and serotonergic rat brain areas after acutely administered medetomidine, a selective alpha 2-adrenoceptor agonist. Pharmacology & toxicology. vol 72. issue 3. 1993-07-22. PMID:8100065. |
reduced turnover of dopamine and 5-hydroxytryptamine in discrete dopaminergic, noradrenergic and serotonergic rat brain areas after acutely administered medetomidine, a selective alpha 2-adrenoceptor agonist. |
1993-07-22 |
2023-08-12 |
rat |
| J C Winter, R A Rabi. Discriminative stimulus properties of m-chlorophenylpiperazine. Pharmacology, biochemistry, and behavior. vol 45. issue 1. 1993-07-19. PMID:8516361. |
in addition, because of mcpp's relative selectivity for the 5-hydroxytryptamine c(5-ht1c) receptor subjects trained with mcpp may prove valuable in assessing the respective functional contributions of 5-ht1c sites to the actions of a variety of serotonergic agents. |
1993-07-19 |
2023-08-12 |
human |
| S F Ali, G D Newport, A C Scallet, Z Binienda, S A Ferguson, J R Bailey, M G Paule, W Slikke. Oral administration of 3,4-methylenedioxymethamphetamine (MDMA) produces selective serotonergic depletion in the nonhuman primate. Neurotoxicology and teratology. vol 15. issue 2. 1993-07-15. PMID:7685472. |
combined with previous data from this laboratory, these results indicate that the decreased concentrations of 5-ht and 5-hiaa in selected brain regions show a selective dose-response relationship for mdma-induced neurotoxicity as measured by serotonergic depletion in the nonhuman primate. |
1993-07-15 |
2023-08-12 |
human |
| M Ginefri-Gayet, J Gaye. Hypothermia induced by infusion of methionine sulfoximine into the dorsal raphe nucleus of the rat: involvement of 5-HT1A and GABAB receptors. European journal of pharmacology. vol 235. issue 2-3. 1993-07-13. PMID:8389714. |
in conclusion, local infusion of mso into the drn must have slowed down the rate of 5-ht turnover in serotonergic neurons and decreased the release and synthesis of gaba. |
1993-07-13 |
2023-08-12 |
rat |
| L Svensson, C Fahlke, E Hård, J A Enge. Involvement of the serotonergic system in ethanol intake in the rat. Alcohol (Fayetteville, N.Y.). vol 10. issue 3. 1993-07-09. PMID:8507391. |
a two-bottle, free-choice paradigm was used to investigate the influence of the serotonergic (5-ht) system on ethanol intake in genetically heterogeneous wistar rats. |
1993-07-09 |
2023-08-12 |
rat |
| S Winberg, A A Myrberg, G E Nilsso. Predator exposure alters brain serotonin metabolism in bicolour damselfish. Neuroreport. vol 4. issue 4. 1993-07-01. PMID:7684616. |
predator exposure (lasting 2 h), which took place in an aquarium where a transparent wall separated the damselfish from the predator (a graysby, epinephelus cruentatus), resulted in increased concentrations of 5-hydroxyindoleacetic acid (5-hiaa, the main serotonin metabolite) and 1.6-1.8 fold elevations of 5-hiaa/serotonin ratios (an index of serotonergic activity) in telencephalon, hypothalamus and brain stem. |
1993-07-01 |
2023-08-12 |
Not clear |
| J W Lanc. Current concepts of migraine pathogenesis. Neurology. vol 43. issue 6 Suppl 3. 1993-06-28. PMID:8502382. |
whether 5-ht is effective in central pain control pathways, the serotonergic projection to the cerebral cortex, its direct action on the cranial blood vessels, or its action at all three sites remains uncertain. |
1993-06-28 |
2023-08-12 |
Not clear |
| L B Hurd, W D Eldre. Synaptic microcircuitry of bipolar and amacrine cells with serotonin-like immunoreactivity in the retina of the turtle, Pseudemys scripta elegans. Visual neuroscience. vol 10. issue 3. 1993-06-24. PMID:8494799. |
although serotonin is thought to be a neurotransmitter in a number of retinal systems, much of the precise synaptic connectivity of serotonergic neurons is unknown. |
1993-06-24 |
2023-08-12 |
Not clear |
| L B Hurd, W D Eldre. Synaptic microcircuitry of bipolar and amacrine cells with serotonin-like immunoreactivity in the retina of the turtle, Pseudemys scripta elegans. Visual neuroscience. vol 10. issue 3. 1993-06-24. PMID:8494799. |
to address this issue, we used an antiserum directed against serotonin to label serotonergic bipolar and amacrine cells in the turtle retina. |
1993-06-24 |
2023-08-12 |
Not clear |
| M D Kelland, A S Freeman, J Rubin, L A Chiod. Ascending afferent regulation of rat midbrain dopamine neurons. Brain research bulletin. vol 31. issue 5. 1993-06-22. PMID:8495379. |
sciatic nerve stimulation-induced inhibition of nigrostriatal da (nsda) neurons was blocked by both pcpa (5-ht synthesis inhibitor) and 5,7-dht (5-ht neurotoxin), suggesting mediation by a serotonergic (5-ht) system. |
1993-06-22 |
2023-08-12 |
rat |
| T Siegal, T Siega. Serotonergic manipulations in experimental neoplastic spinal cord compression. Journal of neurosurgery. vol 78. issue 6. 1993-06-10. PMID:7683713. |
serotonergic manipulations include in vivo inhibition of serotonin (5-ht) synthesis by p-chlorophenylalanine (p-cpa) and in vivo blockage of serotonin type 2 (5-ht2) receptors either by the selective antagonist ketanserin or by cyproheptadine. |
1993-06-10 |
2023-08-12 |
rat |
| J R Simon, B Ghett. Is there a significant somatodendritic uptake of dopamine in the substantia nigra? Evidence from the weaver mutant mouse. Neurochemistry international. vol 22. issue 5. 1993-06-10. PMID:8485453. |
the observed accumulation of [3h]dopamine was apparently taking place predominantly into serotonergic and noradrenergic elements since significant reductions were obtained by both fluoxetine and desipramine at concentrations that were selective for the serotonin and norepinephrine carriers, respectively. |
1993-06-10 |
2023-08-12 |
mouse |
| A J Dekker, L J Tha. Independent effects of cholinergic and serotonergic lesions on acetylcholine and serotonin release in the neocortex of the rat. Neurochemical research. vol 18. issue 3. 1993-05-27. PMID:7683117. |
independent effects of cholinergic and serotonergic lesions on acetylcholine and serotonin release in the neocortex of the rat. |
1993-05-27 |
2023-08-12 |
rat |
| D Bruns, F Engert, H D Lu. A fast activating presynaptic reuptake current during serotonergic transmission in identified neurons of Hirudo. Neuron. vol 10. issue 4. 1993-05-21. PMID:8386524. |
an electrogenic serotonin (5-ht) uptake process was characterized in the serotonergic retzius-p cell synapse of the leech, and the simultaneous activation of this presynaptic reuptake and the postsynaptic response was monitored during evoked transmitter release. |
1993-05-21 |
2023-08-12 |
Not clear |
| C L Bethe. Colocalization of progestin receptors with serotonin in raphe neurons of macaque. Neuroendocrinology. vol 57. issue 1. 1993-05-21. PMID:8479605. |
in summary, progesterone can have a direct action on 5ht neuronal function and thereby influence those endocrine and affective systems under serotonergic control. |
1993-05-21 |
2023-08-12 |
human |
| F Chaoulof. Physiopharmacological interactions between stress hormones and central serotonergic systems. Brain research. Brain research reviews. vol 18. issue 1. 1993-05-11. PMID:8467346. |
the recent progress in 5-hydroxytryptamine (5-ht) receptor pharmacology has helped to define the means by which central serotonergic activity may alter the respective activities of the sns (sympathetic nerves and adrenomedulla) and of the hpa axis. |
1993-05-11 |
2023-08-12 |
Not clear |
| M T Martín, A G Fernández, E Fernández, E Goñalon. Receptors implicated in the actions of serotonin on chicken ileum longitudinal smooth muscle. Life sciences. vol 52. issue 16. 1993-05-03. PMID:8464335. |
several serotonergic agonists were assayed to further analyse the type of receptors involved in the response to 5-ht. |
1993-05-03 |
2023-08-12 |
chicken |
| M Tanaka, H Okamura, N Yanaihara, Y Tanaka, Y Ibat. Differential expression of serotonin and [Met]enkephalin-Arg6-Gly7-Leu8 in neurons of the rat brain stem. Brain research bulletin. vol 30. issue 5-6. 1993-04-26. PMID:8457905. |
in midbrain and pons serotonergic cell groups (b5-b9), no coexistence of 5-ht and meagl was detected. |
1993-04-26 |
2023-08-12 |
rat |