| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Le Corre, P Cheminea. Serotonergic 5HT2 receptors mediate the inhibitory action of serotonin on luteinizing hormone secretion in ovariectomized, estradiol-treated ewes that are refractory to short days. Biology of reproduction. vol 49. issue 1. 1993-09-22. PMID:8353180. |
previous studies with high doses of cyproheptadine suggested that serotonergic (5ht) neural mechanisms participate in the photoperiodic inhibition of secretion of lh in ovariectomized estradiol-treated ewes. |
1993-09-22 |
2023-08-12 |
Not clear |
| Q Li, M S Brownfield, G Battaglia, T M Cabrera, A D Levy, P A Rittenhouse, L D van de Ka. Long-term treatment with the antidepressants fluoxetine and desipramine potentiates endocrine responses to the serotonin agonists 6-chloro-2-[1-piperazinyl]-pyrazine (MK-212) and (+-)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane HCl (DOI). The Journal of pharmacology and experimental therapeutics. vol 266. issue 2. 1993-09-17. PMID:8394920. |
various endocrine responses to 5-hydroxytryptamine (serotonin, 5-ht) agonists were used to assess serotonergic receptor function after chronic treatment with the antidepressants fluoxetine (10 mg/kg), a 5-ht uptake blocker and the norepinephrine uptake blocker desipramine (dmi, 5 mg/kg). |
1993-09-17 |
2023-08-12 |
Not clear |
| W Wu, R Elde, M W Wessendor. Organization of the serotonergic innervation of spinal neurons in rats--III. Differential serotonergic innervation of somatic and parasympathetic preganglionic motoneurons as determined by patterns of co-existing peptides. Neuroscience. vol 55. issue 1. 1993-09-15. PMID:7688880. |
the spinal cord is innervated by brainstem serotonergic neurons, some of which contain substance p and/or thyrotropin-releasing hormone in addition to serotonin. |
1993-09-15 |
2023-08-12 |
rat |
| M Yoshioka, M Matsumoto, H Togashi, C B Smith, H Sait. Opioid receptor regulation of 5-hydroxytryptamine release from the rat hippocampus measured by in vivo microdialysis. Brain research. vol 613. issue 1. 1993-09-15. PMID:8394180. |
these findings indicate that mu-opioid receptors modulate the physiological release of 5-ht from serotonergic neurons in the rat hippocampus. |
1993-09-15 |
2023-08-12 |
rat |
| M Matsumoto, H Togashi, M Yoshioka, M Hirokami, M Tochihara, T Ikeda, C B Smith, H Sait. Inhibitory effects of clonidine on serotonergic neuronal activity as measured by cerebrospinal fluid serotonin and its metabolite in anesthetized rats. Life sciences. vol 53. issue 8. 1993-09-13. PMID:8102468. |
inhibitory effects of clonidine on serotonergic neuronal activity as measured by cerebrospinal fluid serotonin and its metabolite in anesthetized rats. |
1993-09-13 |
2023-08-12 |
rat |
| M Matsumoto, H Togashi, M Yoshioka, M Hirokami, M Tochihara, T Ikeda, C B Smith, H Sait. Inhibitory effects of clonidine on serotonergic neuronal activity as measured by cerebrospinal fluid serotonin and its metabolite in anesthetized rats. Life sciences. vol 53. issue 8. 1993-09-13. PMID:8102468. |
clonidine-induced changes in the serotonergic neuronal activity of the central nervous system were estimated by measuring the concentrations of serotonin (5-ht) and its major metabolite, 5-hydroxyindole-3-acetic acid (5-hiaa), in the cerebrospinal fluid (csf) of anesthetized rats. |
1993-09-13 |
2023-08-12 |
rat |
| M Candito, F Askenazy, M Myquel, P Chambon, G Darcour. Tryptophanemia and tyrosinemia in adolescents with impulsive behavior. International clinical psychopharmacology. vol 8. issue 2. 1993-09-09. PMID:8345161. |
tryptophan (trp) and tyrosine (tyr), respectively the circulating precursors of the central serotonergic (5-ht) and catecholamine systems, were measured in eight adolescents with impulsive behavior regardless of the exact type of disorder. |
1993-09-09 |
2023-08-12 |
human |
| P A Rittenhouse, A D Levy, Q Li, C L Bethea, L D Van de Ka. Neurons in the hypothalamic paraventricular nucleus mediate the serotonergic stimulation of prolactin secretion via 5-HT1c/2 receptors. Endocrinology. vol 133. issue 2. 1993-09-03. PMID:8344205. |
these studies examined the hypothalamic site and receptor subtype mediating the serotonergic (5-ht) control of prl secretion in conscious male rats. |
1993-09-03 |
2023-08-12 |
rat |
| P A Rittenhouse, A D Levy, Q Li, C L Bethea, L D Van de Ka. Neurons in the hypothalamic paraventricular nucleus mediate the serotonergic stimulation of prolactin secretion via 5-HT1c/2 receptors. Endocrinology. vol 133. issue 2. 1993-09-03. PMID:8344205. |
p-chloroamphetamine, a 5-ht releaser, is postulated to enter serotonergic nerve terminals through the 5-ht uptake mechanism, which can be inhibited by fluoxetine. |
1993-09-03 |
2023-08-12 |
rat |
| P A Rittenhouse, A D Levy, Q Li, C L Bethea, L D Van de Ka. Neurons in the hypothalamic paraventricular nucleus mediate the serotonergic stimulation of prolactin secretion via 5-HT1c/2 receptors. Endocrinology. vol 133. issue 2. 1993-09-03. PMID:8344205. |
the 5-ht uptake inhibitor fluoxetine almost completely prevented this increase, demonstrating that p-chloroamphetamine increases prl release via a serotonergic mechanism. |
1993-09-03 |
2023-08-12 |
rat |
| U B Muthane, P Satishchandra, M N Subhas. Visual and auditory evoked potentials in early onset Parkinson's disease and their relationship to cerebrospinal fluid monoamine metabolites. Movement disorders : official journal of the Movement Disorder Society. vol 8. issue 3. 1993-09-02. PMID:7688076. |
we studied visual (vep) and brainstem auditory (baep) evoked potential changes in 23 patients with early onset parkinson's disease (eopd) to establish the nature of the changes as well as their relationship to dopaminergic (da) and serotonergic (5-ht) disturbances, as determined by cerebrospinal fluid levels of homovanillic acid (hva) and 5-hydroxyindoleacetic acid (5-hiaa). |
1993-09-02 |
2023-08-12 |
Not clear |
| C H Lin, S R Haadsma-Svensson, G Phillips, R B McCall, M F Piercey, M W Smith, K Svensson, A Carlsson, C G Chidester, P F Von Voigtlande. Synthesis and biological activity of cis-(3aR)-(-)-2,3,3a,4,5,9b-hexahydro- 3-propyl-1H-benz[e]indole-9-carboxamide: a potent and selective 5-HT1A receptor agonist with good oral availability. Journal of medicinal chemistry. vol 36. issue 15. 1993-08-31. PMID:8340922. |
this compound potently reduced rectal temperature in mice, decreased the firing rate of rat midbrain serotonergic neurons, and suppressed rat brain 5-ht synthesis. |
1993-08-31 |
2023-08-12 |
mouse |
| L N Yatham, M Steine. Neuroendocrine probes of serotonergic function: a critical review. Life sciences. vol 53. issue 6. 1993-08-31. PMID:8341131. |
neuroendocrine probes of serotonergic function are based on the premise that serotonin (5-ht) exhibits an excitory influence on the release of certain anterior pituitary hormones and that the extent of release of these hormones following a challenge with a 5-ht agonist would provide an index of central 5-ht activity. |
1993-08-31 |
2023-08-12 |
human |
| L N Yatham, M Steine. Neuroendocrine probes of serotonergic function: a critical review. Life sciences. vol 53. issue 6. 1993-08-31. PMID:8341131. |
the rapid development and availability of more specific and stereo-selective 5-ht agonists/antagonists seem to indicate that it will not be too long before a valid neuroendocrine test for the assessment of serotonergic function emerges. |
1993-08-31 |
2023-08-12 |
human |
| T J Feuerstein, A Mutschler, A Lupp, V Van Velthoven, E Schlicker, M Göther. Endogenous noradrenaline activates alpha 2-adrenoceptors on serotonergic nerve endings in human and rat neocortex. Journal of neurochemistry. vol 61. issue 2. 1993-08-24. PMID:8393085. |
slices from human neocortex preincubated with [3h]serotonin ([3h]5-ht) were superfused and stimulated electrically to investigate whether the alpha 2-adrenoceptors on serotonergic terminals can be stimulated by endogenous noradrenaline (na) released from neighboring noradrenergic fibers. |
1993-08-24 |
2023-08-12 |
human |
| H Akaoka, G Aston-Jone. Indirect serotonergic agonists attenuate neuronal opiate withdrawal. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8332249. |
two results from our laboratory led us to study the effect of enhanced serotonergic neurotransmission on withdrawal-induced lc hyperactivity: (i) a substantial part of such lc hyperactivity is mediated by an excitatory amino acid input to the locus coeruleus, and (ii) 5-ht selectively attenuates excitation of lc neurons mediated by excitatory amino acids. |
1993-08-19 |
2023-08-12 |
human |
| H Dabadie, M Geffar. Identification of tryptamine and tryptamine-serotonin neurons in the rat dorsal raphe nuclei using specific antibodies. Synapse (New York, N.Y.). vol 14. issue 2. 1993-08-18. PMID:7687387. |
previous studies have shown that tryptamine (t) is closely associated with the serotonergic system but have failed to determine whether neurons containing only t exist in the raphe nuclei (rn) and/or if t colocalizes with serotonin (5-ht). |
1993-08-18 |
2023-08-12 |
rat |
| J A Lawrence, H J Olverman, K Shirakawa, J S Kelly, S P Butche. Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. Brain research. vol 612. issue 1-2. 1993-08-13. PMID:7687192. |
binding of 5-ht1a receptor and 5-ht transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. |
1993-08-13 |
2023-08-12 |
rat |
| J A Lawrence, H J Olverman, K Shirakawa, J S Kelly, S P Butche. Binding of 5-HT1A receptor and 5-HT transporter ligands in rat cortex and hippocampus following cholinergic and serotonergic lesions. Brain research. vol 612. issue 1-2. 1993-08-13. PMID:7687192. |
the binding of the 5-ht transporter ligand, [3h]citalopram was unaffected by the cholinergic lesion whereas binding was reduced in both the hippocampus and cortex following serotonergic lesions. |
1993-08-13 |
2023-08-12 |
rat |
| N A Darman. Role of the inhibitory adrenergic alpha 2 and serotonergic 5-HT1A components of cocaine's actions on the DOI-induced head-twitch response in 5-HT2-receptor supersensitive mice. Pharmacology, biochemistry, and behavior. vol 45. issue 2. 1993-08-11. PMID:8392199. |
the present results further support the previously suggested hypothesis that acute cocaine administration inhibits the 5-ht2-receptor function by increasing the synaptic concentration of norepinephrine and serotonin via inhibition of their uptake and therefore indirectly stimulating the respective inhibitory adrenergic alpha 2- and serotonergic 5-ht1a-receptors. |
1993-08-11 |
2023-08-12 |
mouse |