| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Frisch, D Postilnick, R Rockah, E Michaelovsky, S Postilnick, E Birman, N Laor, B Rauchverger, A Kreinin, M Poyurovsky, M Schneidman, I Modai, R Weizma. Association of unipolar major depressive disorder with genes of the serotonergic and dopaminergic pathways. Molecular psychiatry. vol 4. issue 4. 1999-10-18. PMID:10483058. |
in the present study, 102 unipolar mdd patients and 172 healthy controls were genotyped for polymorphisms in four serotonergic and three dopaminergic candidate genes [tryptophan hydroxylase (tph), serotonin receptor 2a (htr2a), serotonin receptor 2c (htr2c), serotonin transporter promoter region (5-httlpr), dopamine receptor d4 (drd4), dopamine transporter (dat1) and catechol-o-methyl transferase (comt)]. |
1999-10-18 |
2023-08-12 |
Not clear |
| L M Gershtein, E L Dovedov. Regulation by delta-sleep-inducing peptide of the neurochemical changes in the brain associated with dopaminergic system hyperactivity. Neurochemical research. vol 24. issue 9. 1999-10-18. PMID:10485584. |
the parameters of serotonergic system (mao a activity, 5-ht, and 5-hiaa contents) and of dopaminergic system (mao b activity, da, na, and hva contents) were investigated in the cortex and caudate nucleus of control, da or amphetamine, and dsip receiving rats. |
1999-10-18 |
2023-08-12 |
rat |
| C I Woods, W J Azered. Noradrenergic and serotonergic projections to the superior olive: potential for modulation of olivocochlear neurons. Brain research. vol 836. issue 1-2. 1999-10-15. PMID:10415400. |
the distribution and density of noradrenergic (na) and serotonergic (5-ht) varicosities in the superior olive (so) and periolivary region (po) and their relationship to olivocochlear neurons was studied. |
1999-10-15 |
2023-08-12 |
Not clear |
| G Figueras, V Pérez, O San Martino, E Alvarez, F Artiga. Pretreatment platelet 5-HT concentration predicts the short-term response to paroxetine in major depression. Grupo de Trastornos Afectivos. Biological psychiatry. vol 46. issue 4. 1999-10-14. PMID:10459402. |
a previous retrospective study revealed that a high pretreatment platelet serotonin (5-ht) concentration was associated with a low response to serotonergic antidepressants in drug-free major depressives. |
1999-10-14 |
2023-08-12 |
Not clear |
| N Koutouvidis, M Pratikakis, A Fotiado. The use of mirtazapine in a group of 11 patients following poor compliance to selective serotonin reuptake inhibitor treatment due to sexual dysfunction. International clinical psychopharmacology. vol 14. issue 4. 1999-10-14. PMID:10468319. |
mirtazapine, a noradrenergic and specific serotonergic antidepressant, displays strong serotonin (5-ht)2 blocking properties, which may be related to lack of sexual dysfunction. |
1999-10-14 |
2023-08-12 |
Not clear |
| K Herrick-Davis, E Grinde, C M Niswende. Serotonin 5-HT2C receptor RNA editing alters receptor basal activity: implications for serotonergic signal transduction. Journal of neurochemistry. vol 73. issue 4. 1999-10-14. PMID:10501219. |
serotonin 5-ht2c receptor rna editing alters receptor basal activity: implications for serotonergic signal transduction. |
1999-10-14 |
2023-08-12 |
human |
| C A Fornal, F J Martin, C W Metzler, B L Jacob. Pindolol, a putative 5-hydroxytryptamine(1A) antagonist, does not reverse the inhibition of serotonergic neuronal activity induced by fluoxetine in awake cats: comparison to WAY-100635. The Journal of pharmacology and experimental therapeutics. vol 291. issue 1. 1999-10-12. PMID:10490908. |
pindolol, a putative 5-hydroxytryptamine(1a) antagonist, does not reverse the inhibition of serotonergic neuronal activity induced by fluoxetine in awake cats: comparison to way-100635. |
1999-10-12 |
2023-08-12 |
Not clear |
| C A Fornal, F J Martin, C W Metzler, B L Jacob. Pindolol, a putative 5-hydroxytryptamine(1A) antagonist, does not reverse the inhibition of serotonergic neuronal activity induced by fluoxetine in awake cats: comparison to WAY-100635. The Journal of pharmacology and experimental therapeutics. vol 291. issue 1. 1999-10-12. PMID:10490908. |
the ability of pindolol to enhance the clinical antidepressant response to selective serotonin reuptake inhibitors (ssris) is generally attributed to a blockade of the feedback inhibition of serotonergic neuronal activity mediated by somatodendritic 5-hydroxytryptamine (5-ht)(1a) autoreceptors. |
1999-10-12 |
2023-08-12 |
Not clear |
| C A Fornal, F J Martin, C W Metzler, B L Jacob. Pindolol suppresses serotonergic neuronal activity and does not block the inhibition of serotonergic neurons produced by 8-hydroxy-2-(di-n-propylamino)tetralin in awake cats. The Journal of pharmacology and experimental therapeutics. vol 291. issue 1. 1999-10-12. PMID:10490909. |
clinical studies have shown that pindolol can enhance the effects of antidepressant drugs, presumably by acting as an antagonist at somatodendritic 5-hydroxytryptamine (5-ht)(1a) autoreceptors, which regulate the firing rate of central serotonergic neurons. |
1999-10-12 |
2023-08-12 |
Not clear |
| D K Raap, L D Van de Ka. Selective serotonin reuptake inhibitors and neuroendocrine function. Life sciences. vol 65. issue 12. 1999-10-07. PMID:10503938. |
selective serotonin (5-ht) reuptake inhibitors (ssris) are effective drugs for the treatment of several neuropsychiatric disorders associated with reduced serotonergic function. |
1999-10-07 |
2023-08-12 |
Not clear |
| O Berton, M Durand, S Aguerre, P Mormède, F Chaoulof. Behavioral, neuroendocrine and serotonergic consequences of single social defeat and repeated fluoxetine pretreatment in the Lewis rat strain. Neuroscience. vol 92. issue 1. 1999-10-06. PMID:10392854. |
except for a decrease in midbrain serotonin transporter density, fluoxetine did not affect the other serotonergic indices analysed herein, i.e. |
1999-10-06 |
2023-08-12 |
human |
| A Hinney, H Herrmann, T Löhr, K Rosenkranz, A Ziegler, G Lehmkuhl, F Poustka, M H Schmidt, H Mayer, W Siegfried, H Remschmidt, J Hebebran. No evidence for an involvement of alleles of polymorphisms in the serotonin1Dbeta and 7 receptor genes in obesity, underweight or anorexia nervosa. International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. vol 23. issue 7. 1999-10-05. PMID:10454111. |
the serotonergic (5-hydroxytryptamine, 5-ht) system has been implicated in body weight regulation and in the etiology of anorexia nervosa (an). |
1999-10-05 |
2023-08-12 |
Not clear |
| J Levenson, J H Byrne, A Eski. Levels of serotonin in the hemolymph of Aplysia are modulated by light/dark cycles and sensitization training. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 18. 1999-10-04. PMID:10479709. |
effects of injections of 5-ht and the morphology of the serotonergic system of aplysia indicate that 5-ht may have a humoral, in addition to a neurotransmitter, role. |
1999-10-04 |
2023-08-12 |
aplysia |
| N A Khan, J P Poisso. 5-HT3 receptor-channels coupled with Na+ influx in human T cells: role in T cell activation. Journal of neuroimmunology. vol 99. issue 1. 1999-10-04. PMID:10496177. |
serotonin and an agonist of 5-ht3 receptor-channels, 2-methyl-5ht, evoked na+ influx, whereas the agonists of other serotonergic receptor subtypes, i.e., 5-ht1a and 5-ht1b receptors, failed to induce na+ influx in these cells. |
1999-10-04 |
2023-08-12 |
human |
| J D Higley, A J Bennet. Central nervous system serotonin and personality as variables contributing to excessive alcohol consumption in non-human primates. Alcohol and alcoholism (Oxford, Oxfordshire). vol 34. issue 3. 1999-09-30. PMID:10414617. |
developmental and behavioural correlates of central nervous system (cns) serotonergic activity, as measured by concentrations of the serotonin metabolite 5-hydroxyindol-3-ylacetic acid (5-hiaa) in the cerebrospinal fluid (csf), were used to investigate neurogenetic influences on alcohol consumption, as well as personality traits that characterize excessive alcohol intake. |
1999-09-30 |
2023-08-12 |
human |
| A M Donovan, J M Halperin, J H Newcorn, V Sharm. Thermal response to serotonergic challenge and aggression in attention deficit hyperactivity disorder children. Journal of child and adolescent psychopharmacology. vol 9. issue 2. 1999-09-30. PMID:10461818. |
body temperature change in response to the serotonergic (5-ht) enhancer, d,l-fenfluramine (fen), was examined in 27 prepubescent boys diagnosed with attention deficit hyperactivity disorder (adhd) to determine (1) the utility of this measure as an index of central serotonergic function; and (2) if the magnitude of temperature change is associated with aggression. |
1999-09-30 |
2023-08-12 |
Not clear |
| F Lévy, M Meurisse, G Ferreira, J Thibault, Y Tille. Afferents to the rostral olfactory bulb in sheep with special emphasis on the cholinergic, noradrenergic and serotonergic connections. Journal of chemical neuroanatomy. vol 16. issue 4. 1999-09-28. PMID:10450873. |
by using immunocytochemical techniques, retrogradely labeled neurons were colocalized with choline acetyltransferase, tyrosine hydroxylase, dopamine-beta-hydroxylase and serotonin to characterize cholinergic, noradrenergic and serotonergic fluoro-gold-labeled neurons. |
1999-09-28 |
2023-08-12 |
Not clear |
| S T Kaehler, N Singewald, A Philipp. Dependence of serotonin release in the locus coeruleus on dorsal raphe neuronal activity. Naunyn-Schmiedeberg's archives of pharmacology. vol 359. issue 5. 1999-09-28. PMID:10498288. |
changes in blood pressure and release of serotonin elicited by stimulating or lesioning the drn point to the importance of serotonergic neurons extending between this raphe nucleus and the locus coeruleus in central cardiovascular control. |
1999-09-28 |
2023-08-12 |
rat |
| T Inoue, S Itoh, M Kobayashi, Y Kang, R Matsuo, S Wakisaka, T Morimot. Serotonergic modulation of the hyperpolarizing spike afterpotential in rat jaw-closing motoneurons by PKA and PKC. Journal of neurophysiology. vol 82. issue 2. 1999-09-23. PMID:10444661. |
because the slope of the linear relationship between firing frequency and injected current was increased only when the mahp amplitude was decreased by 5-ht, it is suggested that the relation between incoming synaptic inputs and firing output in jcmns varies according to serotonergic effects on jcmns and calcium-dependent modulation of its effects. |
1999-09-23 |
2023-08-12 |
rat |
| L Prime, Y Pichon, L E Moor. N-Methyl-D-aspartate-induced oscillations in whole cell clamped neurons from the isolated spinal cord of Xenopus laevis embryos. Journal of neurophysiology. vol 82. issue 2. 1999-09-23. PMID:10444699. |
because these observations were made at embryonic stages where little or no serotonergic innervation exists, it is likely that nmda-induced intrinsic oscillatory activity in xenopus embryonic neurons does not require 5-ht. |
1999-09-23 |
2023-08-12 |
xenopus_laevis |