| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D Galter, M Böttner, K Krieglstein, E Schömig, K Unsicke. Differential regulation of distinct phenotypic features of serotonergic neurons by bone morphogenetic proteins. The European journal of neuroscience. vol 11. issue 7. 1999-07-30. PMID:10383634. |
alterations in 5-ht neuron numbers were due to the induction of serotonergic markers rather than increased survival, as shown by the efficacy of short-term treatments. |
1999-07-30 |
2023-08-12 |
rat |
| X R Jiang, M Z Wrona, G Dryhurs. Tryptamine-4,5-dione, a putative endotoxic metabolite of the superoxide-mediated oxidation of serotonin, is a mitochondrial toxin: possible implications in neurodegenerative brain disorders. Chemical research in toxicology. vol 12. issue 5. 1999-07-27. PMID:10328753. |
the release and subsequent reuptake of 5-hydroxytryptamine (5-ht) and cytoplasmic superoxide (o2-*) generation have both been implicated as important factors associated with the degeneration of serotonergic neurons evoked by methamphetamine (ma) and cerebral ischemia-reperfusion (i-r). |
1999-07-27 |
2023-08-12 |
rat |
| X R Jiang, M Z Wrona, G Dryhurs. Tryptamine-4,5-dione, a putative endotoxic metabolite of the superoxide-mediated oxidation of serotonin, is a mitochondrial toxin: possible implications in neurodegenerative brain disorders. Chemical research in toxicology. vol 12. issue 5. 1999-07-27. PMID:10328753. |
such observations raise the possibility that tryptamine-4,5-dione (t-4,5-d), the major in vitro product of the o2-*-mediated oxidation of 5-ht, might be an endotoxicant that contributes to serotonergic neurodegeneration. |
1999-07-27 |
2023-08-12 |
rat |
| C Gemma, L Imeri, M Manci. Hippocampal type 1 (movement-related) theta rhythm positively correlates with serotonergic activity. Archives italiennes de biologie. vol 137. issue 2-3. 1999-07-23. PMID:10349493. |
to investigate the relationship between the hippocampal [symbol: see text] activity (or rhythmical slow activity, rsa) and the hippocampal serotonergic activity during spontaneous behavior, simultaneous recordings of i) hippocampal eeg, ii) sleep-wake activity, and iii) hippocampal levels of the serotonin (5-ht) metabolite 5-hydroxyndolacetic acid (5-hiaa--measured by in vivo voltammetry and infrared telemetry) were performed. |
1999-07-23 |
2023-08-12 |
Not clear |
| C Gemma, L Imeri, M Manci. Hippocampal type 1 (movement-related) theta rhythm positively correlates with serotonergic activity. Archives italiennes de biologie. vol 137. issue 2-3. 1999-07-23. PMID:10349493. |
since in the experimental conditions used in the study, 5-hiaa levels are a reliable index of 5-ht release, the results support the hypothesis that hippocampal type 1 rsa is generated by a serotonergic mechanism. |
1999-07-23 |
2023-08-12 |
Not clear |
| D Galter, M Böttner, K Unsicke. Developmental regulation of the serotonergic transmitter phenotype in rostral and caudal raphe neurons by transforming growth factor-betas. Journal of neuroscience research. vol 56. issue 5. 1999-07-23. PMID:10369219. |
serotonergic (5-ht) neurons of the cns develop as two separate clusters, a rostral and a caudal group, within the brain stem raphe. |
1999-07-23 |
2023-08-12 |
rat |
| D Galter, M Böttner, K Unsicke. Developmental regulation of the serotonergic transmitter phenotype in rostral and caudal raphe neurons by transforming growth factor-betas. Journal of neuroscience research. vol 56. issue 5. 1999-07-23. PMID:10369219. |
alterations in 5-ht neuron numbers were due to the induction of serotonergic markers rather than increased survival, as shown by the efficacy of delayed short-term treatments. |
1999-07-23 |
2023-08-12 |
rat |
| H S Kim, Y R Son, S H Ki. Nitric oxide synthase inhibitors enhance 5-HT2 receptor-mediated behavior, the head-twitch response in mice. Life sciences. vol 64. issue 26. 1999-07-22. PMID:10403505. |
in the present study, nos inhibitors, n(g)-nitro-l-arginine, n(g)-nitro-l-arginine methylester, n(g)-monomethyl-l-arginine, 7-nitroindazole, trifluoperazine and no scavenger, methylene blue markedly enhanced 5-hydroxytryptamine (5-ht)-induced selective serotonergic behavior, the head twitch response (htr), in mice. |
1999-07-22 |
2023-08-12 |
mouse |
| B J Yates, J A Smail, S D Stocker, J P Car. Transneuronal tracing of neural pathways controlling activity of diaphragm motoneurons in the ferret. Neuroscience. vol 90. issue 4. 1999-07-16. PMID:10338316. |
double-labeling studies revealed that although the infected midline neurons were located in the proximity of serotonergic neurons, only a small number of the virus-containing cells were positive for serotonin. |
1999-07-16 |
2023-08-12 |
Not clear |
| V Ljubic-Thibal, A Morin, M Diksic, E Hame. Origin of the serotonergic innervation to the rat dorsolateral hypothalamus: retrograde transport of cholera toxin and upregulation of tryptophan hydroxylase mRNA expression following selective nerve terminals lesion. Synapse (New York, N.Y.). vol 32. issue 3. 1999-07-15. PMID:10340628. |
the regulation of serotonin synthesis was investigated in the serotonergic neurons, which provide afferents to the dorsolateral hypothalamus (dlh). |
1999-07-15 |
2023-08-12 |
rat |
| V Ljubic-Thibal, A Morin, M Diksic, E Hame. Origin of the serotonergic innervation to the rat dorsolateral hypothalamus: retrograde transport of cholera toxin and upregulation of tryptophan hydroxylase mRNA expression following selective nerve terminals lesion. Synapse (New York, N.Y.). vol 32. issue 3. 1999-07-15. PMID:10340628. |
disruption of serotonin synthesis steady-state was induced unilaterally by a selective and local destruction of serotonergic nerve terminals with 5,7-dihydroxytryptamine (5,7-dht), stereotaxically injected in the right dlh. |
1999-07-15 |
2023-08-12 |
rat |
| R Ciccociopp. The role of serotonin in craving: from basic research to human studies. Alcohol and alcoholism (Oxford, Oxfordshire). vol 34. issue 2. 1999-07-07. PMID:10344784. |
based on studies suggesting that the brain serotonergic system plays a central role in the regulation of impulse-control mechanisms, it is proposed that 5-ht deficiency may contribute to the loss of control over drug-taking, which is a crucial factor for the maintenance of addictive behaviour. |
1999-07-07 |
2023-08-12 |
human |
| L Buydens-Branchey, M Branchey, J Hudson, M Rothman, P Fergeson, C McKerni. Serotonergic function in cocaine addicts: prolactin responses to sequential D,L-fenfluramine challenges. Biological psychiatry. vol 45. issue 10. 1999-07-02. PMID:10349036. |
we therefore assessed the central serotonergic responsivity of cocaine addicts and control subjects by neuroendocrine challenges with the serotonin releaser and reuptake inhibitor d,l-fenfluramine (fen). |
1999-07-02 |
2023-08-12 |
human |
| T Shinkai, O Ohmori, H Kojima, T Terao, T Suzuki, K Ab. Association study of the 5-HT6 receptor gene in schizophrenia. American journal of medical genetics. vol 88. issue 2. 1999-06-28. PMID:10206228. |
serotonergic (5-hydroxytryptamine; 5-ht) transmission may play an important role in the treatment and/or pathogenesis of schizophrenia. |
1999-06-28 |
2023-08-12 |
Not clear |
| H S Kim, I S Park, H K Lim, H S Cho. NMDA receptor antagonists enhance 5-HT2 receptor-mediated behavior, head-twitch response, in PCPA-treated mice. Archives of pharmacal research. vol 22. issue 2. 1999-06-28. PMID:10230499. |
previous work in our laboratory has shown that the n-methyl-d-aspartate (nmda) receptor antagonists, ap-5, cpp, mk-801, ketamine, dextrorphan and dextromethorphan cause a pronounced enhancement of 5-hydroxytryptamine (5-ht)-induced head-twitch response (htr) in intact mice, suggesting the involvement of nmda receptors in the glutamatergic modulation of serotonergic function at the postsynaptic 5-ht2 receptors. |
1999-06-28 |
2023-08-12 |
mouse |
| M L Wadenberg, K A Young, J T Richter, P B Hick. Effects of local application of 5-hydroxytryptamine into the dorsal or median raphe nuclei on haloperidol-induced catalepsy in the rat. Neuropharmacology. vol 38. issue 1. 1999-06-24. PMID:10193906. |
the reversal of cat by local application of 5-ht (40 microg) into the dr was significant also at 70 min after 5-ht administration, with the same tendency for 5-ht injections into the mr. at this time interval, other serotonergic behavioral symptoms like head twitches and wet-dog shakes also emerged. |
1999-06-24 |
2023-08-12 |
rat |
| M L Wadenberg, K A Young, J T Richter, P B Hick. Effects of local application of 5-hydroxytryptamine into the dorsal or median raphe nuclei on haloperidol-induced catalepsy in the rat. Neuropharmacology. vol 38. issue 1. 1999-06-24. PMID:10193906. |
the early reversal of cat by local 5-ht administration into the mr is in all probability mediated via stimulation of 5-ht1a autoreceptors on raphe serotonergic cell bodies. |
1999-06-24 |
2023-08-12 |
rat |
| B Lerer, Y Gelfin, M Gorfine, B Allolio, K P Lesch, M E Newma. 5-HT1A receptor function in normal subjects on clinical doses of fluoxetine: blunted temperature and hormone responses to ipsapirone challenge. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 6. 1999-06-24. PMID:10327431. |
serotonergic receptors of the 5-ht1a subtype have been suggested to play a pivotal role in the mechanism of action of antidepressant drugs, including specific serotonin reuptake inhibitors (ssris). |
1999-06-24 |
2023-08-12 |
human |
| E Lenzinger, A Neumeister, N Praschak-Rieder, K Fuchs, E Gerhard, M Willeit, W Sieghart, S F Kasper, K Hornik, H N Aschaue. Behavioral effects of tryptophan depletion in seasonal affective disorder associated with the serotonin transporter gene? Psychiatry research. vol 85. issue 3. 1999-06-24. PMID:10333377. |
the serotonin transporter is known to play a critical role in the termination of serotonergic neurotransmission by sodium-dependent uptake of 5-ht into the presynaptic neuron. |
1999-06-24 |
2023-08-12 |
human |
| M M Meguid, S O Fetissov, G Miyata, G F Torell. Feeding pattern in obese Zucker rats after dopaminergic and serotonergic LHA grafts. Neuroreport. vol 10. issue 5. 1999-06-23. PMID:10321483. |
to study the role of the lateral hypothalamic area (lha) dopamine and serotonin in the regulation of feeding pattern during obesity, embryonic dopaminergic and serotonergic neurons from mesencephalon and rombencephalon of lean rats were grafted into the lha of adult obese zucker rats. |
1999-06-23 |
2023-08-12 |
rat |