| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R J Kavoussi, R L Hauger, E F Coccar. Prolactin response to d-fenfluramine in major depression before and after treatment with serotonin reuptake inhibitors. Biological psychiatry. vol 45. issue 3. 1999-05-07. PMID:10023505. |
serotonergic challenge studies before and after treatment of depressed patients have yielded conflicting results; however, these studies have not focused on the effect of antidepressant treatment with selective serotonin reuptake inhibitors (ssris) on serotonergic challenge studies. |
1999-05-07 |
2023-08-12 |
Not clear |
| M D Underwood, V Arango, M J Bakalian, D A Ruggiero, J J Man. Dorsal raphe nucleus serotonergic neurons innervate the rostral ventrolateral medulla in rat. Brain research. vol 824. issue 1. 1999-05-05. PMID:10095041. |
we examined whether serotonergic (5-ht) projections from the drn terminate in the rostral ventrolateral medulla (rvl) and if so, whether the projection mediates cardiovascular responses to drn stimulation. |
1999-05-05 |
2023-08-12 |
rat |
| W Kaye, K Gendall, M Strobe. Serotonin neuronal function and selective serotonin reuptake inhibitor treatment in anorexia and bulimia nervosa. Biological psychiatry. vol 44. issue 9. 1999-05-04. PMID:9807638. |
these data raise the possibility that a disturbance of serotonin activity may create a vulnerability for the expression of a cluster of symptoms that are common to both an and bn and that nutritional factors may affect ssri response in depression, obsessive-compulsive disorder, or other conditions characterized by disturbances in serotonergic pathways. |
1999-05-04 |
2023-08-12 |
human |
| N Laflamme, E Feuvrier, D Richard, S Rives. Involvement of serotonergic pathways in mediating the neuronal activity and genetic transcription of neuroendocrine corticotropin-releasing factor in the brain of systemically endotoxin-challenged rats. Neuroscience. vol 88. issue 1. 1999-04-26. PMID:10051203. |
the fact that serotonin depletion largely prevented activation of neurosecretory parvocellular neurons of the paraventricular nucleus of the hypothalamus and neuroendocrine corticotropin-releasing factor gene transcription in response to immunogenic challenge provides the evidence that serotonergic system is part of the brain circuitry involved in the corticotroph axis-immune interface. |
1999-04-26 |
2023-08-12 |
rat |
| J P Redrobe, M Bourin, M C Colombel, G B Bake. Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms. Journal of psychopharmacology (Oxford, England). vol 12. issue 4. 1999-04-23. PMID:10065908. |
psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms. |
1999-04-23 |
2023-08-12 |
mouse |
| J P Redrobe, M Bourin, M C Colombel, G B Bake. Psychopharmacological profile of the selective serotonin reuptake inhibitor, paroxetine: implication of noradrenergic and serotonergic mechanisms. Journal of psychopharmacology (Oxford, England). vol 12. issue 4. 1999-04-23. PMID:10065908. |
the present study was designed to evaluate the psychopharmacological profile of the selective serotonin reuptake inhibitor paroxetine, and thus assess potential noradrenergic and/or serotonergic activity. |
1999-04-23 |
2023-08-12 |
mouse |
| D N Thomas, D J Nutt, R B Holma. Sertraline, a selective serotonin reuptake inhibitor modulates extracellular noradrenaline in the rat frontal cortex. Journal of psychopharmacology (Oxford, England). vol 12. issue 4. 1999-04-23. PMID:10065910. |
the selective action of selective serotonergic reuptake inhibitors (ssris) on 5-hydroxytryptamine (5-ht) neurotransmission underlies the therapeutic effectiveness of this class of drugs. |
1999-04-23 |
2023-08-12 |
rat |
| M Gill, F LoVecchio, B Selde. Serotonin syndrome in a child after a single dose of fluvoxamine. Annals of emergency medicine. vol 33. issue 4. 1999-04-21. PMID:10092727. |
serotonin syndrome, a potentially fatal iatrogenic complication of psychopharmacologic therapy, is most commonly reported with combinations of serotonergic medications. |
1999-04-21 |
2023-08-12 |
Not clear |
| M B Stei. Neurobiological perspectives on social phobia: from affiliation to zoology. Biological psychiatry. vol 44. issue 12. 1999-04-15. PMID:9861470. |
included in this category are suggestive findings of central serotonergic dysregulation in social phobia, response to serotonin reuptake inhibitors in social phobia, and the role of serotonergic function in septohippocampal models of anxiety. |
1999-04-15 |
2023-08-12 |
human |
| A Mør. Effects of lithium treatment on extracellular serotonin levels in the dorsal hippocampus and wet-dog shakes in the rat. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 8. issue 4. 1999-04-13. PMID:9928915. |
chronic lithium treatment may affect the serotonergic wet-dog shake syndrome in the rat partly via the camp signalling system but does not seem to influence this syndrome by changing the release of 5-ht from nerve terminals in the dorsal hippocampus. |
1999-04-13 |
2023-08-12 |
rat |
| H Wang, M W Wessendor. Mu- and delta-opioid receptor mRNAs are expressed in spinally projecting serotonergic and nonserotonergic neurons of the rostral ventromedial medulla. The Journal of comparative neurology. vol 404. issue 2. 1999-04-13. PMID:9934993. |
in addition, we examined quantitatively the expression of mor1 and dor1 mrnas in spinally projecting rvm neurons including serotonergic (5ht) cells by using in situ hybridization, immunocytochemistry, retrograde tract-tracing, and the physical disector. |
1999-04-13 |
2023-08-12 |
rat |
| Z J Yang, V Blaha, M M Meguid, A Laviano, A Oler, Z Zada. Interleukin-1alpha injection into ventromedial hypothalamic nucleus of normal rats depresses food intake and increases release of dopamine and serotonin. Pharmacology, biochemistry, and behavior. vol 62. issue 1. 1999-04-13. PMID:9972846. |
findings show that an il-1alpha pathophysiological dose injected into the vmn was associated with anorexia and significantly increased dopaminergic and serotonergic activities and suggest that enhanced vmn da and 5-ht activities may be part of an il-1alpha-initiated cascade involved in il-1alpha-associated anorexia. |
1999-04-13 |
2023-08-12 |
rat |
| M Okada, Y Kawata, T Murakami, K Wada, K Mizuno, T Kondo, S Kanek. Differential effects of adenosine receptor subtypes on release and reuptake of hippocampal serotonin. The European journal of neuroscience. vol 11. issue 1. 1999-04-01. PMID:9987006. |
in addition, hippocampal serotonergic transmission might be modulated by hippocampal presynaptic adenosine receptor subtypes, and hippocampal 5-ht reuptake activity might be modulated by hippocampal a3 receptor. |
1999-04-01 |
2023-08-12 |
rat |
| W C Duncan, K A Johnson, T A Weh. 5-HT agonist-induced phase-advances of the circadian pacemaker are diminished by chronic antidepressant drug treatment. Brain research. vol 815. issue 1. 1999-03-30. PMID:9974132. |
because serotonergic interventions alter 5-ht receptor number in the hypothalamus, we asked whether chronic treatment with an antidepressant drug (ad) that modifies serotonergic function could alter the phase-shifting effects of the 5-ht agonist 8-hydroxydipropylaminotetralin (8-oh-dpat). |
1999-03-30 |
2023-08-12 |
Not clear |
| V Compan, L Segu, M C Buhot, A Daszut. Selective increases in serotonin 5-HT1B/1D and 5-HT2A/2C binding sites in adult rat basal ganglia following lesions of serotonergic neurons. Brain research. vol 793. issue 1-2. 1999-03-29. PMID:9630549. |
selective increases in serotonin 5-ht1b/1d and 5-ht2a/2c binding sites in adult rat basal ganglia following lesions of serotonergic neurons. |
1999-03-29 |
2023-08-12 |
rat |
| V Compan, L Segu, M C Buhot, A Daszut. Selective increases in serotonin 5-HT1B/1D and 5-HT2A/2C binding sites in adult rat basal ganglia following lesions of serotonergic neurons. Brain research. vol 793. issue 1-2. 1999-03-29. PMID:9630549. |
quantitative autoradiography was used to examine possible adaptive changes in serotonin 5-ht1b/1d and 5-ht2a/2c receptor binding sites in adult rat basal ganglia, after partial or severe lesions of serotonergic neurons produced by intraraphe injections of variable amounts of 5,7-dihydroxytryptamine. |
1999-03-29 |
2023-08-12 |
rat |
| b' M Maes, A H Lin, R Verkerk, L Delmeire, A Van Gastel, M Van der Planken, S Scharp\\xc3\\xa. Serotonergic and noradrenergic markers of post-traumatic stress disorder with and without major depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 20. issue 2. 1999-03-29. PMID:9885798.' |
the results suggest that (1) serotonergic mechanisms, such as defects in the 5-ht transporter system, may play a role in the pathophysiology of ptsd; and (2) that catecholaminergic mechanisms, such as increased precursor availability and lowered affinity of alpha 2-ars, may play a role in the pathophysiology of ptsd with concurrent md. |
1999-03-29 |
2023-08-12 |
human |
| B D Greenberg, J Benjamin, J D Martin, D Keuler, S J Huang, M Altemus, D L Murph. Delayed obsessive-compulsive disorder symptom exacerbation after a single dose of a serotonin antagonist in fluoxetine-treated but not untreated patients. Psychopharmacology. vol 140. issue 4. 1999-03-29. PMID:9888619. |
enhanced serotonergic transmission may underlie therapeutic effects of serotonin reuptake inhibitors in obsessive-compulsive disorder. |
1999-03-29 |
2023-08-12 |
Not clear |
| J M Gorman, J M Ken. SSRIs and SNRIs: broad spectrum of efficacy beyond major depression. The Journal of clinical psychiatry. vol 60 Suppl 4. 1999-03-25. PMID:10086481. |
these drugs have in common important effects on the serotonergic (5-ht) neurotransmission system, which is involved in mediating a substantial number of important functions, including mood, aggression, sexual behavior, and pain. |
1999-03-25 |
2023-08-12 |
Not clear |
| A Menese. Physiological, pathophysiological and therapeutic roles of 5-HT systems in learning and memory. Reviews in the neurosciences. vol 9. issue 4. 1999-03-23. PMID:9886142. |
consequently, the notion that activation of the 5-ht systems impairs performance, whereas reduced serotonergic function may facilitate learning, must be reconsidered. |
1999-03-23 |
2023-08-12 |
Not clear |