| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J R Moiseiwitsch, J R Raymond, H Tamir, J M Laude. Regulation by serotonin of tooth-germ morphogenesis and gene expression in mouse mandibular explant cultures. Archives of oral biology. vol 43. issue 10. 1998-12-16. PMID:9796780. |
serotonin (5-ht) stimulates tooth-germ development in embryonic mouse mandibular explant cultures, but it is not clear whether this is due to a direct action on epithelial-mesenchymal interactions, or whether development was stimulated indirectly by serotonergic regulation of other morphoregulatory molecules. |
1998-12-16 |
2023-08-12 |
mouse |
| J R Moiseiwitsch, J R Raymond, H Tamir, J M Laude. Regulation by serotonin of tooth-germ morphogenesis and gene expression in mouse mandibular explant cultures. Archives of oral biology. vol 43. issue 10. 1998-12-16. PMID:9796780. |
in contrast serotonergic modulation of s-100beta and tenascin expression was not reversed by any of the 5-ht receptor antagonists tested, although the 5-ht uptake inhibitor, fluoxetine, did reverse the effect of 5-ht on s-100beta expression, as well as tooth-germ development. |
1998-12-16 |
2023-08-12 |
mouse |
| R Mössner, A Heils, G Stöber, O Okladnova, S Daniel, K P Lesc. Enhancement of serotonin transporter function by tumor necrosis factor alpha but not by interleukin-6. Neurochemistry international. vol 33. issue 3. 1998-12-11. PMID:9759920. |
serotonergic neurotransmission is regulated by the 5-ht transporter (5-htt), which determines the magnitude and duration of serotonergic responses. |
1998-12-11 |
2023-08-12 |
Not clear |
| D Schmitz, T Gloveli, R M Empson, U Heineman. Serotonin reduces polysynaptic inhibition via 5-HT1A receptors in the superficial entorhinal cortex. Journal of neurophysiology. vol 80. issue 3. 1998-12-03. PMID:9744926. |
the superficial cells of the entorhinal cortex (ec), main input to the hippocampus, receive a serotonergic input from the raphe nuclei and express 5-hydroxytryptamine creatine sulfate complex (5-ht) receptors at high density. |
1998-12-03 |
2023-08-12 |
Not clear |
| P Rosel, B Arranz, J Vallejo, M Oros, J M Crespo, J M Menchon, M A Navarr. Variations in [3H]imipramine and 5-HT2A but not [3H]paroxetine binding sites in suicide brains. Psychiatry research. vol 82. issue 3. 1998-11-30. PMID:9754440. |
taken together, these results suggest that the 5-ht uptake site measured with [3h]imipramine and the 5-ht2a receptors are reliable markers of serotonergic dysfunction. |
1998-11-30 |
2023-08-12 |
human |
| K Nakajima, K Matsuyama, S Mor. Prenatal administration of para-chlorophenylalanine results in suppression of serotonergic system and disturbance of swimming movements in newborn rats. Neuroscience research. vol 31. issue 2. 1998-11-20. PMID:9700721. |
postnatal development of the spinal cord serotonergic (5-ht) system and of swimming movements were studied in newborn sprague-dawley rats, in which the serotonin level in the central nervous system was lowered in the prenatal period. |
1998-11-20 |
2023-08-12 |
rat |
| B Gutiérrez, L Pintor, C Gastó, A Rosa, J Bertranpetit, E Vieta, L Fañaná. Variability in the serotonin transporter gene and increased risk for major depression with melancholia. Human genetics. vol 103. issue 3. 1998-11-19. PMID:9799087. |
the serotonin transporter (sert) gene is a particularly interesting candidate for genetic involvement in affective disorders owing to its role in both the regulation of serotonergic neurotransmission and the mechanism of action of many antidepressant drugs. |
1998-11-19 |
2023-08-12 |
human |
| B Olivier, R van Oorschot, M D Waldinge. Serotonin, serotonergic receptors, selective serotonin reuptake inhibitors and sexual behaviour. International clinical psychopharmacology. vol 13 Suppl 6. 1998-11-18. PMID:9728669. |
serotonin, serotonergic receptors, selective serotonin reuptake inhibitors and sexual behaviour. |
1998-11-18 |
2023-08-12 |
mouse |
| B Olivier, R van Oorschot, M D Waldinge. Serotonin, serotonergic receptors, selective serotonin reuptake inhibitors and sexual behaviour. International clinical psychopharmacology. vol 13 Suppl 6. 1998-11-18. PMID:9728669. |
the ssris are intriguing drugs; by blocking presynaptic and somatodendritic serotonin transporters, they enhance serotonergic neurotransmission and thereby activate serotonin receptors. |
1998-11-18 |
2023-08-12 |
mouse |
| N D Ryan, D Varm. Child and adolescent mood disorders--experience with serotonin-based therapies. Biological psychiatry. vol 44. issue 5. 1998-11-16. PMID:9755355. |
aggregating all available data, much of which is relatively new, it seems most likely that noradrenergic and mixed serotonergic/noradrenergic tricyclic antidepressants are ineffective in child and adolescent depression, whereas serotonergic antidepressants (e.g., selective serotonin reuptake inhibitors) are probably effective). |
1998-11-16 |
2023-08-12 |
Not clear |
| C DeBattista, M Sofuoglu, A F Schatzber. Serotonergic synergism: the risks and benefits of combining the selective serotonin reuptake inhibitors with other serotonergic drugs. Biological psychiatry. vol 44. issue 5. 1998-11-16. PMID:9755356. |
serotonergic synergism: the risks and benefits of combining the selective serotonin reuptake inhibitors with other serotonergic drugs. |
1998-11-16 |
2023-08-12 |
Not clear |
| C DeBattista, M Sofuoglu, A F Schatzber. Serotonergic synergism: the risks and benefits of combining the selective serotonin reuptake inhibitors with other serotonergic drugs. Biological psychiatry. vol 44. issue 5. 1998-11-16. PMID:9755356. |
it has become common clinical practice to combine the selective serotonin reuptake inhibitors with other serotonergic agents for augmentation or adjunctive purposes. |
1998-11-16 |
2023-08-12 |
Not clear |
| C DeBattista, M Sofuoglu, A F Schatzber. Serotonergic synergism: the risks and benefits of combining the selective serotonin reuptake inhibitors with other serotonergic drugs. Biological psychiatry. vol 44. issue 5. 1998-11-16. PMID:9755356. |
also growing is a literature that suggests that even the most apparently benign combinations of serotonergic drugs carry at least some risk of serious pharmacokinetic or pharmacodynamic drug interactions, such as a serotonin syndrome. |
1998-11-16 |
2023-08-12 |
Not clear |
| T E Hunt, W H Wu, V K Zbuze. The effects of serotonin biosynthesis inhibition on nicotine and nifedipine-induced analgesia in rats. Anesthesia and analgesia. vol 87. issue 5. 1998-11-16. PMID:9806690. |
because both nifedipine- and nicotine-induced analgesia involve serotonergic mechanisms, we studied the effects of the serotonin biosynthesis inhibitor parachlorophenylalanine (pcpa) on nifedipine- and nicotine-induced analgesia. |
1998-11-16 |
2023-08-12 |
rat |
| T E Hunt, W H Wu, V K Zbuze. The effects of serotonin biosynthesis inhibition on nicotine and nifedipine-induced analgesia in rats. Anesthesia and analgesia. vol 87. issue 5. 1998-11-16. PMID:9806690. |
these data further support the involvement of the serotonergic system in both nifedipine- and nicotine-induced analgesia and suggest that drugs that affect serotonin levels, including tricyclic antidepressants and serotonin-specific reuptake inhibitors, may also affect the analgesia induced by nifedipine and nicotine. |
1998-11-16 |
2023-08-12 |
rat |
| D T Malone, D A Taylo. Modulation of delta9-tetrahydrocannabinol-induced hypothermia by fluoxetine in the rat. British journal of pharmacology. vol 124. issue 7. 1998-11-13. PMID:9723953. |
increased extracellular 5-ht can activate autoreceptors which may decrease serotonergic activity, thereby reducing the delta9-thc-induced hypothermia. |
1998-11-13 |
2023-08-12 |
rat |
| R M Sibug, J C Compaan, O C Meijer, J Van der Gugten, B Olivier, E R De Kloe. Flesinoxan treatment reduces 5-HT1A receptor mRNA in the dentate gyrus independently of high plasma corticosterone levels. European journal of pharmacology. vol 353. issue 2-3. 1998-11-13. PMID:9726650. |
it is concluded that flesinoxan reduces 5-ht1a receptor expression in the dentate gyrus both through homologous downregulation and a corticosterone-mediated effect on the serotonergic (5-ht) system. |
1998-11-13 |
2023-08-12 |
rat |
| D J Nutt, C J Bell, A L Malizi. Brain mechanisms of social anxiety disorder. The Journal of clinical psychiatry. vol 59 Suppl 17. 1998-11-13. PMID:9811424. |
serotonergic pathways may play a role in social anxiety disorder, as shown by the clinical effectiveness of selective serotonin reuptake inhibitors, plus fenfluramine and m-chlorophenylpiperazine challenge studies. |
1998-11-13 |
2023-08-12 |
human |
| P G de Vism. [Neurotoxicity of the drug Ecstasy. Functional consequences of serotonergic hypoactivity]. Ugeskrift for laeger. vol 160. issue 42. 1998-11-09. PMID:9800515. |
animal research involving ecstasy has shown lasting damage to serotonergic axons and terminals, leading to reduced serotonin transmission in the cns. |
1998-11-09 |
2023-08-12 |
human |
| J L Rubenstei. Development of serotonergic neurons and their projections. Biological psychiatry. vol 44. issue 3. 1998-11-06. PMID:9693386. |
it also covers the development of serotonergic axon pathways and the potential role of serotonin in regulating developmental processes. |
1998-11-06 |
2023-08-12 |
Not clear |