| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Leander, N Vrang, M Mølle. Neuronal projections from the mesencephalic raphe nuclear complex to the suprachiasmatic nucleus and the deep pineal gland of the golden hamster (Mesocricetus auratus). The Journal of comparative neurology. vol 399. issue 1. 1998-11-03. PMID:9725702. |
thus, this study of the golden hamster shows a serotonergic projection from the median raphe nucleus to the suprachiasmatic nucleus and a projection from the dorsal raphe nucleus to the deep pineal gland supporting physiological indications of an influence of serotonin on the photoreceptive circadian system of the brain. |
1998-11-03 |
2023-08-12 |
Not clear |
| R J Kavoussi, J Kramer, R L Hauger, E F Coccar. Prolactin response to D-fenfluramine in outpatients with major depression. Psychiatry research. vol 79. issue 3. 1998-11-02. PMID:9704866. |
in order to test the serotonin hypothesis of depression, the authors compared 20 outpatients with major depressive disorder to 20 normal control subjects using prolactin response to d-fenfluramine as a measure of central serotonergic (5-ht) functioning. |
1998-11-02 |
2023-08-12 |
human |
| R E GOSSELIN, K E MOORE, A S MILTO. Physiological control of molluscan gill cilia by 5-hydroxytryptamine. The Journal of general physiology. vol 46. 1998-11-01. PMID:13949402. |
which cells of the gill synthesize and destroy 5-ht has not been established, but these observations support the concept that the physiological activity of lamellibranch gill cilia is controlled by a serotonergic mechanism. |
1998-11-01 |
2023-08-12 |
Not clear |
| D L Murphy, A M Andrews, C H Wichems, Q Li, M Tohda, B Greenber. Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs. The Journal of clinical psychiatry. vol 59 Suppl 15. 1998-10-27. PMID:9786305. |
brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs. |
1998-10-27 |
2023-08-12 |
Not clear |
| D L Murphy, A M Andrews, C H Wichems, Q Li, M Tohda, B Greenber. Brain serotonin neurotransmission: an overview and update with an emphasis on serotonin subsystem heterogeneity, multiple receptors, interactions with other neurotransmitter systems, and consequent implications for understanding the actions of serotonergic drugs. The Journal of clinical psychiatry. vol 59 Suppl 15. 1998-10-27. PMID:9786305. |
a group of selective serotonin reuptake inhibitors (ssris) remain the agents with greatest therapeutic utility, although the mechanisms underlying their delayed efficacy, which clearly result from adaptive consequences following repeated administration rather than early uptake inhibition of serotonin by itself, are incompletely understood and appear to involve changes in signal transduction and gene expression in serotonergic and other neurotransmitter systems. |
1998-10-27 |
2023-08-12 |
Not clear |
| A K Malhotra, D Goldman, C Mazzanti, A Clifton, A Breier, D Picka. A functional serotonin transporter (5-HTT) polymorphism is associated with psychosis in neuroleptic-free schizophrenics. Molecular psychiatry. vol 3. issue 4. 1998-10-26. PMID:9702741. |
the serotonin transporter (5-htt) plays a critical role in regulation of serotonergic function. |
1998-10-26 |
2023-08-12 |
human |
| S Pauli, A C Linthorst, J M Reu. Tumour necrosis factor-alpha and interleukin-2 differentially affect hippocampal serotonergic neurotransmission, behavioural activity, body temperature and hypothalamic-pituitary-adrenocortical axis activity in the rat. The European journal of neuroscience. vol 10. issue 3. 1998-10-22. PMID:9753154. |
time-dependent changes in serotonergic neurotransmission and hpa axis activity were determined by measuring serotonin, its metabolite 5-hydroxyindoleacetic acid and free corticosterone in dialysates. |
1998-10-22 |
2023-08-12 |
human |
| I S Shiah, L N Yatha. GABA function in mood disorders: an update and critical review. Life sciences. vol 63. issue 15. 1998-10-22. PMID:9768867. |
given that gaba has an inhibitory effect on biogenic amine neurotransmitters such as norepinephrine and serotonin and this inhibition may be involved in local circuits and interneurons, it has been suggested that the hypothesis of a gaba deficit in mood disorders does not compete with but complements the well-established hypotheses of alterations in noradrenergic and serotonergic function in mood disorders. |
1998-10-22 |
2023-08-12 |
Not clear |
| R D Buñag, L W Davido. Does chronic ketanserin treatment enhance bradycardia in old rats by serotonergic blockade? Aging (Milan, Italy). vol 10. issue 2. 1998-10-20. PMID:9666190. |
on the other hand, serotonergic blockade seems a more likely explanation because reversal or enhancement by ketanserin of cardiovascular responses to serotonin was age-related, being more marked in 14- and 24- than in 4-month-old rats. |
1998-10-20 |
2023-08-12 |
rat |
| Y W Li, D A Baylis. Electrophysical properties, synaptic transmission and neuromodulation in serotonergic caudal raphe neurons. Clinical and experimental pharmacology & physiology. vol 25. issue 6. 1998-10-16. PMID:9673827. |
we studied electrophysiological properties, synaptic transmission and modulation by 5-hydroxytryptamine (5-ht) of caudal raphe neurons using whole-cell recording in a neonatal rat brain slice preparation; recorded neurons were identified as serotonergic by post-hoc immunohistochemical detection of tryptophan hydroxylase, the 5-ht-synthesizing enzyme. |
1998-10-16 |
2023-08-12 |
rat |
| Y W Li, D A Baylis. Electrophysical properties, synaptic transmission and neuromodulation in serotonergic caudal raphe neurons. Clinical and experimental pharmacology & physiology. vol 25. issue 6. 1998-10-16. PMID:9673827. |
5-hydroxytryptamine regulates serotonergic neuronal activity of the caudal raphe by decreasing spontaneous activity via somatodendritic 5-ht1a receptors and by inhibiting excitatory synaptic transmission onto these neurons via presynaptic 5-ht1b receptors. |
1998-10-16 |
2023-08-12 |
rat |
| Y W Li, D A Baylis. Electrophysical properties, synaptic transmission and neuromodulation in serotonergic caudal raphe neurons. Clinical and experimental pharmacology & physiology. vol 25. issue 6. 1998-10-16. PMID:9673827. |
these local modulatory mechanisms provide multiple levels of feedback autoregulation of serotonergic raphe neurons by 5-ht. |
1998-10-16 |
2023-08-12 |
rat |
| A Graudins, A Stearman, B Cha. Treatment of the serotonin syndrome with cyproheptadine. The Journal of emergency medicine. vol 16. issue 4. 1998-10-06. PMID:9696181. |
all patients gave a history of recent exposure to one or more serotonergic medications, including moclobemide, paroxetine, sertraline, and venlafaxine, with clinical evidence of serotonin syndrome. |
1998-10-06 |
2023-08-12 |
Not clear |
| J X Chen, H Pan, T P Rothman, P R Wade, M D Gersho. Guinea pig 5-HT transporter: cloning, expression, distribution, and function in intestinal sensory reception. The American journal of physiology. vol 275. issue 3. 1998-10-05. PMID:9724254. |
we tested the hypothesis that guinea pig villus epithelial cells are able to inactivate 5-ht because they express the same 5-ht transporter as serotonergic neurons. |
1998-10-05 |
2023-08-12 |
human |
| G Q Teng, J Williams, L Zhang, R Purdy, W J Pearc. Effects of maturation, artery size, and chronic hypoxia on 5-HT receptor type in ovine cranial arteries. The American journal of physiology. vol 275. issue 3. 1998-10-01. PMID:9728071. |
to test the hypothesis that variations in cerebrovascular reactivity to 5-ht among arteries of different size or type, during maturation, or during acclimatization to high altitude involve differences in serotonergic receptor subtype, we determined relative agonist potency orders and antagonist affinities in common carotid (com), main branch middle cerebral (main), and second branch middle cerebral (2br) arteries from term fetal lambs and nonpregnant adult sheep acclimatized at sea level or at an altitude of 3,820 m for approximately 110 days. |
1998-10-01 |
2023-08-12 |
Not clear |
| A M Kumar, S Weiss, J B Fernandez, D Cruess, C Eisdorfe. Peripheral serotonin levels in women: role of aging and ethnicity. Gerontology. vol 44. issue 4. 1998-09-24. PMID:9657081. |
serotonin has been implicated to play an important role in regulating emotions and behavior, and it is well accepted that the platelet serotonergic system mirrors the presynaptic central serotonergic system. |
1998-09-24 |
2023-08-12 |
Not clear |
| M J Espey, H J Du, J W Downi. Serotonergic modulation of spinal ascending activity and sacral reflex activity evoked by pelvic nerve stimulation in cats. Brain research. vol 798. issue 1-2. 1998-09-11. PMID:9666094. |
the effects of intrathecal administration of serotonergic agents were examined to determine whether spinal and supraspinal responses to bladder afferent activation were modulated by 5-ht. |
1998-09-11 |
2023-08-12 |
Not clear |
| M D Waldinger, H H Berendsen, B F Blok, B Olivier, G Holsteg. Premature ejaculation and serotonergic antidepressants-induced delayed ejaculation: the involvement of the serotonergic system. Behavioural brain research. vol 92. issue 2. 1998-09-10. PMID:9638953. |
we describe here the neurophysiology and the peripheral neuroanatomy of ejaculation and provide a review of the involvement of serotonin in the central nervous system in relation to serotonergic nuclei and their projections. |
1998-09-10 |
2023-08-12 |
Not clear |
| D Wei, I M Maisonneuve, M E Kuehne, S D Glic. Acute iboga alkaloid effects on extracellular serotonin (5-HT) levels in nucleus accumbens and striatum in rats. Brain research. vol 800. issue 2. 1998-09-04. PMID:9685673. |
these and other data suggest that (1) the serotonergic system may not be an essential factor in the anti-addictive actions of these drugs; (2) ibogaine (or an unidentified metabolite) may release serotonin as well as inhibit its reuptake; (3) stimulation of the ascending serotonergic system may mediate ibogaine's hallucinogenic effect; and (4) 18-mc probably has no affinity for the serotonin transporter, and is unlikely to be a hallucinogen. |
1998-09-04 |
2023-08-12 |
rat |
| J F O'Hanlon, H W Robbe, A Vermeeren, C van Leeuwen, P E Danjo. Venlafaxine's effects on healthy volunteers' driving, psychomotor, and vigilance performance during 15-day fixed and incremental dosing regimens. Journal of clinical psychopharmacology. vol 18. issue 3. 1998-09-03. PMID:9617980. |
the drug's selectively impairing effect on vigilance is shared by other "serotonergic" anxiolytics and antidepressants, suggesting that interference with 5-ht transmission reduces arousal in particularly monotonous tasks or environments. |
1998-09-03 |
2023-08-12 |
human |