| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Szabó, B L Butz, R H Alpe. Further characterization of forebrain serotonin receptors mediating tachycardia in conscious rats. Brain research bulletin. vol 45. issue 6. 1998-06-08. PMID:9566502. |
furthermore, the full response is dependent on afferent serotonergic innervation, suggesting a presynaptic modulatory role for 5-ht in the preoptic area. |
1998-06-08 |
2023-08-12 |
rat |
| D Schmitz, T Gloveli, R M Empson, A Draguhn, U Heineman. Serotonin reduces synaptic excitation in the superficial medial entorhinal cortex of the rat via a presynaptic mechanism. The Journal of physiology. vol 508 ( Pt 1). 1998-05-29. PMID:9490827. |
the superficial layers ii and iii of the entorhinal cortex, which form the main cortical input to the hippocampus, receive a large serotonergic projection from the raphe nuclei and express 5-ht receptors at high density. |
1998-05-29 |
2023-08-12 |
rat |
| T E Moffitt, G L Brammer, A Caspi, J P Fawcett, M Raleigh, A Yuwiler, P Silv. Whole blood serotonin relates to violence in an epidemiological study. Biological psychiatry. vol 43. issue 6. 1998-05-28. PMID:9532350. |
for study of an epidemiological sample we examined blood serotonin, because certain physiological and behavioral findings suggested that it might serve as an analog marker for serotonergic function. |
1998-05-28 |
2023-08-12 |
Not clear |
| G D'Andrea, F Granella, M Alecci, G C Manzon. Serotonin metabolism in cluster headache. Cephalalgia : an international journal of headache. vol 18. issue 2. 1998-05-27. PMID:9533605. |
despite some evidence of the involvement of the serotonergic system in cluster headache (ch) pathophysiology, the serotonin (5ht) metabolism has so far been poorly studied. |
1998-05-27 |
2023-08-12 |
human |
| J Hennig, A Kroeger, B Meyer, H Prochaska, P Krien, S Huwe, P Nette. Personality correlates of +/- pindolol induced decreases in prolactin. Pharmacopsychiatry. vol 31. issue 1. 1998-05-21. PMID:9524980. |
since reduced (blunted) prl-responses after 5-ht challenge tests have been reported for impulsives, the present results favor the involvement of primarily serotonergic and probably only secondarily dopaminergic control of +/- pindolol induced prl decreases. |
1998-05-21 |
2023-08-12 |
human |
| L Lima, M Urbin. Serotonergic projections to the retina of rat and goldfish. Neurochemistry international. vol 32. issue 2. 1998-05-19. PMID:9542725. |
the study of these serotonergic projections from the brain to the retina could be of interest in the understanding of the functional role of serotonin in the retina. |
1998-05-19 |
2023-08-12 |
mouse |
| D L Dow-Edward. Preweaning cocaine administration alters the adult response to quipazine: comparison with fluoxetine. Neurotoxicology and teratology. vol 20. issue 2. 1998-05-14. PMID:9536459. |
because the majority of effects are seen during the initial portion of the behavioral session, a time of heightened activity in response to a novel environment, the data suggest that inhibition of the 5-ht transporter during the preweaning period alters serotonergic influences over novelty-induced activity but that brief periods of inhibition or other actions of cocaine, such as those at the catecholamine transporters, prevent this from happening, particularly in males. |
1998-05-14 |
2023-08-12 |
human |
| K B Zajicek, J D Higley, S J Suomi, M Linnoil. Rhesus macaques with high CSF 5-HIAA concentrations exhibit early sleep onset. Psychiatry research. vol 73. issue 1-2. 1998-05-11. PMID:9463835. |
the relationship between central nervous system serotonergic activity, as reflected by cerebrospinal fluid (csf) concentrations of the serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa), and sleep/wakefulness behavior was investigated in socially housed, juvenile rhesus macaques. |
1998-05-11 |
2023-08-12 |
human |
| G Vogal, J Cohen, D Mullis, T Kensler, S Kaplit. Nefazodone and REM sleep: how do antidepressant drugs decrease REM sleep? Sleep. vol 21. issue 1. 1998-05-05. PMID:9485534. |
since n is a potent serotonin reuptake blocker, the present findings that n had no effect on rem sleep cast doubt on the hypothesis that antidepressant drugs decrease rem sleep by increasing serotonergic neurotransmission. |
1998-05-05 |
2023-08-12 |
human |
| L Romero, B Jernej, N Bel, L Cicin-Sain, R Cortés, F Artiga. Basal and stimulated extracellular serotonin concentration in the brain of rats with altered serotonin uptake. Synapse (New York, N.Y.). vol 28. issue 4. 1998-04-30. PMID:9517840. |
we examined the relationship between the density of serotonergic (5-hydroxytryptamine [5-ht]) uptake sites and extracellular 5-ht concentration in the rat brain using microdialysis with two different models, lesions with 5,7-dihydroxytryptamine (50 microg in the dorsal raphe nucleus (drn) 15 days before) and sublines of rats genetically selected displaying extreme values of platelet 5-ht uptake. |
1998-04-30 |
2023-08-12 |
rat |
| L Romero, B Jernej, N Bel, L Cicin-Sain, R Cortés, F Artiga. Basal and stimulated extracellular serotonin concentration in the brain of rats with altered serotonin uptake. Synapse (New York, N.Y.). vol 28. issue 4. 1998-04-30. PMID:9517840. |
thus, basal extracellular 5-ht (but not 5-hiaa) concentrations are largely independent on the density of serotonergic innervation and associated changes in uptake sites. |
1998-04-30 |
2023-08-12 |
rat |
| N A Darmani, J Shaddy, E L Elde. Prolonged deficits in presynaptic serotonin function following withdrawal from chronic cocaine exposure as revealed by 5-HTP-induced head-twitch response in mice. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 11-12. 1998-04-29. PMID:9503268. |
overall, the present results suggest that enduring deficits occur in presynaptic serotonin neurochemistry and serotonergic adaptive mechanisms are exquisitely sensitive to chronic administration of low- and high-doses of cocaine. |
1998-04-29 |
2023-08-12 |
mouse |
| S M Stah. Basic psychopharmacology of antidepressants, part 1: Antidepressants have seven distinct mechanisms of action. The Journal of clinical psychiatry. vol 59 Suppl 4. 1998-04-23. PMID:9554316. |
three other classes of antidepressants, like the ssris, increase serotonergic neurotransmission, but they also have additional actions, namely dual serotonin and norepinephrine reuptake inhibition (venlafaxine); serotonin-2 antagonism/reuptake inhibition (nefazodone); and alpha2 antagonism plus serotonin-2 and -3 antagonism (mirtazapine). |
1998-04-23 |
2023-08-12 |
Not clear |
| R J Verkes, R C Van der Mast, M W Hengeveld, J P Tuyl, A H Zwinderman, G M Van Kempe. Reduction by paroxetine of suicidal behavior in patients with repeated suicide attempts but not major depression. The American journal of psychiatry. vol 155. issue 4. 1998-04-22. PMID:9546002. |
because selective serotonin reuptake inhibitors (ssris) enhance serotonergic function, the authors studied the efficacy of an ssri, paroxetine, in the prevention of recurrent suicidal behavior. |
1998-04-22 |
2023-08-12 |
Not clear |
| L C Daws, G M Toney, D J Davis, G A Gerhardt, A Fraze. In vivo chronoamperometric measurements of the clearance of exogenously applied serotonin in the rat dentate gyrus. Journal of neuroscience methods. vol 78. issue 1-2. 1998-04-14. PMID:9497010. |
male sprague-dawley rats were anaesthetized and a nafion-coated, carbon fiber electrode, attached to a multibarrel pipette, was lowered into the subgranular layer of the dentate gyrus, a region which receives dense serotonergic innervation, or the corpus callosum, a fiber tract relatively devoid of the 5-ht transporter (sert). |
1998-04-14 |
2023-08-12 |
rat |
| L C Daws, G M Toney, D J Davis, G A Gerhardt, A Fraze. In vivo chronoamperometric measurements of the clearance of exogenously applied serotonin in the rat dentate gyrus. Journal of neuroscience methods. vol 78. issue 1-2. 1998-04-14. PMID:9497010. |
similarly, signals produced by locally applied 5-ht in the dentate gyrus of rats following destruction of hippocampal serotonergic innervation with 5,7-dihydroxytryptamine (5,7-dht), were significantly enhanced compared to those observed in control animals. |
1998-04-14 |
2023-08-12 |
rat |
| S R Hansson, E Mezey, B J Hoffma. Serotonin transporter messenger RNA in the developing rat brain: early expression in serotonergic neurons and transient expression in non-serotonergic neurons. Neuroscience. vol 83. issue 4. 1998-04-14. PMID:9502257. |
serotonin transporter messenger rna in the developing rat brain: early expression in serotonergic neurons and transient expression in non-serotonergic neurons. |
1998-04-14 |
2023-08-12 |
rat |
| J P Welsh, B Chang, M E Menaker, S A Aiche. Removal of the inferior olive abolishes myoclonic seizures associated with a loss of olivary serotonin. Neuroscience. vol 82. issue 3. 1998-04-09. PMID:9483543. |
the deficit in olivary serotonin was verified physiologically and pharmacologically by a reduced sensitivity of the genetically epilepsy-prone rat to the tremorogenic effect of harmaline, which is known to produce tremor through a mechanism that requires serotonergic innervation of the inferior olive. |
1998-04-09 |
2023-08-12 |
rat |
| T Nakazato, A Akiyam. Immediate and long-term effects of 5,7-dihydroxytryptamine on rat striatal serotonergic neurons measured using in vivo voltammetry. Neurochemical research. vol 23. issue 1. 1998-04-03. PMID:9482260. |
the long-term effect of 5,7-dht lesions may attributable to increased synthesis of serotonin or decreased reuptake in remaining serotonergic neurons. |
1998-04-03 |
2023-08-12 |
rat |
| C M Portas, B Bjorvatn, S Fagerland, J Grønli, V Mundal, E Sørensen, R Ursi. On-line detection of extracellular levels of serotonin in dorsal raphe nucleus and frontal cortex over the sleep/wake cycle in the freely moving rat. Neuroscience. vol 83. issue 3. 1998-04-02. PMID:9483564. |
our findings are consistent with previous results in cats, and suggest that in rats also, extracellular 5-hydroxytryptamine levels in dorsal raphe nucleus and frontal cortex across the sleep/wake cycle might reflect serotonergic neuronal activity. |
1998-04-02 |
2023-08-12 |
rat |