| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R Teufel-Mayer, J Gleit. Effects of long-term administration of hypericum extracts on the affinity and density of the central serotonergic 5-HT1 A and 5-HT2 A receptors. Pharmacopsychiatry. vol 30 Suppl 2. 1997-11-26. PMID:9342771. |
in this context, serotonergic (5-ht) receptors are of special interest. |
1997-11-26 |
2023-08-12 |
rat |
| V Fenik, L Kubin, S Okabe, A I Pack, R O Davie. Differential sensitivity of laryngeal and pharyngeal motoneurons to iontophoretic application of serotonin. Neuroscience. vol 81. issue 3. 1997-11-24. PMID:9316035. |
hypoglossal and laryngeal motoneurons were recorded extracellularly using five-barrel pipettes filled with: serotonin, glutamate and methysergide (serotonergic antagonist) for iontophoresis, and nacl for recording and current balancing. |
1997-11-24 |
2023-08-12 |
Not clear |
| J Luthman, M N Friedemann, B J Hoffer, G A Gerhard. In vivo electrochemical measurements of serotonin clearance in rat striatum: effects of neonatal 6-hydroxydopamine-induced serotonin hyperinnervation and serotonin uptake inhibitors. Journal of neural transmission (Vienna, Austria : 1996). vol 104. issue 4-5. 1997-11-21. PMID:9295172. |
clearance times of 5-ht decreased, while amplitudes and rise times increased with serotonergic hyperinnervation induced by neonatal 6-hydroxydopamine (6-ohda) lesions of dopamine (da) neurons. |
1997-11-21 |
2023-08-12 |
rat |
| J Benton, R Huber, M Ruchhoeft, S Helluy, B Belt. Serotonin depletion by 5,7-dihydroxytryptamine alters deutocerebral development in the lobster, Homarus americanus. Journal of neurobiology. vol 33. issue 4. 1997-11-20. PMID:9322154. |
the role of serotonergic input for the development of these brain structures was investigated in lobster embryos after serotonin had been depleted pharmacologically with the neurotoxin 5,7-dihydroxytryptamine. |
1997-11-20 |
2023-08-12 |
lobster |
| J Benton, R Huber, M Ruchhoeft, S Helluy, B Belt. Serotonin depletion by 5,7-dihydroxytryptamine alters deutocerebral development in the lobster, Homarus americanus. Journal of neurobiology. vol 33. issue 4. 1997-11-20. PMID:9322154. |
the toxin exhibited a high degree of specificity for serotonergic neurons and associated target regions, and serotonin depletion persisted for at least 2 months following treatment. |
1997-11-20 |
2023-08-12 |
lobster |
| L Lidberg, A Dåderma. [Reduced serotonin levels are predisposing to violence. A simple blood test predicts dangerous character]. Lakartidningen. vol 94. issue 39. 1997-11-18. PMID:9379806. |
the level of serotonergic function can be assessed indirectly in several ways: 1. determination of csf (cerebrospinal fluid) content of the serotonin metabolite 5-hiaa (5-hydroxyindoleacetic acid); 2. determination of the plasma level of the amino acid tryptophan, the serotonin precursor (passage of tryptophan into the brain is dependent on the ratio of tryptophan to other competing amino acids); 3. analysis of platelet monoamine oxidase content, a putative correlate of serotonergic capacity in the brain; 4. by determining response to an ogtt (oral glucose tolerance test), another putative correlate of serotonergic function. |
1997-11-18 |
2023-08-12 |
Not clear |
| I H Richard, R Kurla. A survey of antidepressant drug use in Parkinson's disease. Parkinson Study Group. Neurology. vol 49. issue 4. 1997-11-14. PMID:9339713. |
selective serotonin reuptake inhibitors (ssris) are a newer class of antidepressants that may have particular efficacy in parkinson's disease (pd) given the known serotonergic alterations in this disease. |
1997-11-14 |
2023-08-12 |
Not clear |
| E V Gurevich, J N Joyc. Alterations in the cortical serotonergic system in schizophrenia: a postmortem study. Biological psychiatry. vol 42. issue 7. 1997-11-10. PMID:9376449. |
previous studies have suggested a disturbance in the cortical serotonergic (5-ht) system in schizophrenia; however, these studies have been confounded by suicide in the patients groups, which in itself is associated with alterations in the 5-ht system. |
1997-11-10 |
2023-08-12 |
human |
| K A Bever, P J Perr. Dexfenfluramine hydrochloride: an anorexigenic agent. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. vol 54. issue 18. 1997-11-10. PMID:9377205. |
the drug should not be combined with other serotonergic agonists because of the risk of serotonin syndrome. |
1997-11-10 |
2023-08-12 |
Not clear |
| P J Pauwel. 5-HT 1B/D receptor antagonists. General pharmacology. vol 29. issue 3. 1997-11-10. PMID:9378233. |
5-hydroxytryptamine-1b (5-ht 1b, formerly designated 5-ht 1d beta) and 5-hydroxy-tryptamine-1d (5-ht 1d, formerly designated 5-ht 1d alpha) receptors are distinct molecular entities that mediate serotonergic neurotransmission. |
1997-11-10 |
2023-08-12 |
human |
| R Gaggi, R Dall' Olio, M Santangelo, P Roncad. Actions of nimodipine on the serotonergic systems of rat brain. General pharmacology. vol 29. issue 3. 1997-11-10. PMID:9378249. |
it was concluded that the effects of nimodipine on brain 5-ht metabolism appeared to be linked to activation of serotonergic neurotransmission likely due to inhibition of the back-regulation mechanism mediated by presynaptic 5-ht1a receptors. |
1997-11-10 |
2023-08-12 |
rat |
| D C Chugani, O Muzik, R Rothermel, M Behen, P Chakraborty, T Mangner, E A da Silva, H T Chugan. Altered serotonin synthesis in the dentatothalamocortical pathway in autistic boys. Annals of neurology. vol 42. issue 4. 1997-11-07. PMID:9382481. |
based on reports of increased platelet serotonin in 30 to 50% of autistic subjects, abnormal serotonergic neurotransmission may be important in the pathogenesis of autism. |
1997-11-07 |
2023-08-12 |
human |
| M Molai. Serotonin syndrome presenting with migrainelike stroke. Headache. vol 37. issue 8. 1997-11-05. PMID:9329236. |
serotonin syndrome is the result of the drug interaction that enhances serotonergic tone in the central nervous system. |
1997-11-05 |
2023-08-12 |
Not clear |
| A C Egberts, R H Meyboom, F H De Koning, A Bakker, H G Leufken. Non-puerperal lactation associated with antidepressant drug use. British journal of clinical pharmacology. vol 44. issue 3. 1997-10-30. PMID:9296322. |
the aim of the present study was to estimate the relative risk of non-puerperal lactation in patients using antidepressants in general, and specifically for serotonergic (selective serotonin reuptake inhibitors (ssris) and clomipramine) and non-serotonergic antidepressants. |
1997-10-30 |
2023-08-12 |
Not clear |
| C Camaris, D Littl. A fatality due to moclobemide. Journal of forensic sciences. vol 42. issue 5. 1997-10-28. PMID:9304853. |
the few reported fatalities have all been ascribed to serotonin syndrome, due to an interaction between moclobemide and other serotonergic agents. |
1997-10-28 |
2023-08-12 |
Not clear |
| N Ohtani, M Ohta, T Sugan. Microdialysis study of modification of hypothalamic neurotransmitters in streptozotocin-diabetic rats. Journal of neurochemistry. vol 69. issue 4. 1997-10-27. PMID:9326291. |
the equal increases in dialysate 5-ht and 5-hiaa and the better restoration of the 5-hiaa/5-ht ratio after insulin therapy indicate that serotonergic activity may depend on the levels of circulating insulin more than on noradrenergic activity. |
1997-10-27 |
2023-08-12 |
rat |
| M Di Mascio, E Esposit. The degree of inhibition of dopaminergic neurons in the ventral tegmental area induced by selective serotonin reuptake inhibitors is a function of the density-power-spectrum of the interspike interval. Neuroscience. vol 79. issue 4. 1997-10-23. PMID:9219958. |
it is suggested that this difference in density-power-spectrum could reflect the asymmetry of serotonergic input to the ventral tegmental area da neurons, and the differential effects of selective serotonin reuptake inhibitors on these neurons might depend on the characteristics of their basal firing mode. |
1997-10-23 |
2023-08-12 |
Not clear |
| J Zhang, J A Engel, D M Jackson, C Johansson, L Svensso. (-)Alprenolol potentiates the disrupting effects of dizocilpine on sensorimotor function in the rat. Psychopharmacology. vol 132. issue 3. 1997-10-23. PMID:9292628. |
however, a serotonergic influence was suggested by the fact that a facilitating effect of dizocilpine on asr amplitude was also obtained by pretreatment with the 5-ht precursor, l-5-htp, in benserazide-pretreated rats. |
1997-10-23 |
2023-08-12 |
rat |
| P Koleck. Isolated venlafaxine-induced serotonin syndrome. The Journal of emergency medicine. vol 15. issue 4. 1997-10-22. PMID:9279702. |
serotonin syndrome is a potentially fatal complication of serotonergic drug therapy. |
1997-10-22 |
2023-08-12 |
Not clear |
| P Koleck. Isolated venlafaxine-induced serotonin syndrome. The Journal of emergency medicine. vol 15. issue 4. 1997-10-22. PMID:9279702. |
usually, serotonin syndrome occurs with the concomitant use of two serotonergic drugs; this case report describes a patient with a classic presentation of serotonin syndrome induced solely by a venlafaxine overdose. |
1997-10-22 |
2023-08-12 |
Not clear |