| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Koleck. Isolated venlafaxine-induced serotonin syndrome. The Journal of emergency medicine. vol 15. issue 4. 1997-10-22. PMID:9279702. |
emergency physicians need to be aware that the serotonin syndrome may occur not only with serotonergic drug combinations but also with overdoses of a single potent serotonergic agent such as venlafaxine. |
1997-10-22 |
2023-08-12 |
Not clear |
| L E Ribeiro-do-Vall. Serotonergic neurons in the caudal raphe nuclei discharge in association with activity of masticatory muscles. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 30. issue 1. 1997-10-21. PMID:9222408. |
there is a dense serotonergic projection from nucleus raphe pallidus and nucleus raphe obscurus to the trigeminal motors nucleus and serotonin exerts a strong facilitatory action on the trigeminal motoneurons. |
1997-10-21 |
2023-08-12 |
Not clear |
| G Gerra, R Caccavari, A Zaimovic, M Palladino, B Chittolini, G Giucastro, D Maestri, C Monica, G Fertonani-Affini, R Delsignore, F Brambill. Serotonergic function in mothers of opioid addicts: correlation with comorbid depression. Acta psychiatrica Scandinavica. vol 96. issue 1. 1997-10-21. PMID:9259222. |
the serotonergic (5-ht) function of 36 mothers of heroin addicts, of whom 16 subjects were without psychopathological features (group a) and 20 subjects had major depressive disorders (group b), as well as 10 age- and sex-matched healthy controls, was examined by l-d-fenfluramine stimulation of secretion of prolactin (prl) and cortisol. |
1997-10-21 |
2023-08-12 |
human |
| A Sharma, T Punhani, K C Fon. Distribution of the 5-hydroxytryptamine2C receptor protein in adult rat brain and spinal cord determined using a receptor-directed antibody: effect of 5,7-dihydroxytryptamine. Synapse (New York, N.Y.). vol 27. issue 1. 1997-10-21. PMID:9268064. |
ten days after depletion of 5-ht with the serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-dht), there was a significant increase in 5-ht2c-li in the choroid plexus and the ventral cervical spinal cord, suggesting that receptors therein are located post-synaptic to destroyed serotonergic nerve terminals. |
1997-10-21 |
2023-08-12 |
human |
| R J Verkes, D Fekkes, A H Zwinderman, M W Hengeveld, R C Van der Mast, J P Tuyl, A J Kerkhof, G M Van Kempe. Platelet serotonin and [3H]paroxetine binding correlate with recurrence of suicidal behavior. Psychopharmacology. vol 132. issue 1. 1997-10-20. PMID:9272764. |
the observed association between indicators of platelet serotonin uptake and suicidal behavior suggests a state- and trait-dependency between suicidality and central serotonergic dysfunction. |
1997-10-20 |
2023-08-12 |
Not clear |
| J P Gardner, C A Fornal, B L Jacob. Effects of sleep deprivation on serotonergic neuronal activity in the dorsal raphe nucleus of the freely moving cat. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 17. issue 2. 1997-10-17. PMID:9252982. |
since most pharmacological treatments for depression increase brain serotonin neurotransmission, the purpose of the present study was to determine whether tsd increases the activity of serotonergic neurons in the dorsal raphe nucleus (drn) in cats. |
1997-10-17 |
2023-08-12 |
cat |
| N Bal, G Figueras, M T Vilaró, C Suñol, F Artiga. Antidepressant drugs inhibit a glial 5-hydroxytryptamine transporter in rat brain. The European journal of neuroscience. vol 9. issue 8. 1997-10-16. PMID:9283827. |
the presence of the mrnas for the 5-ht transporter and monoamine oxidase-a (moa-a) was established in cultured astrocytes and in adult rat brain areas with (midbrain and brainstem) and without (frontal cortex) serotonergic cell bodies after reverse transcription-polymerase chain reaction and hybridization with probes complementary to the cloned neuronal 5-ht transporter and mao-a. |
1997-10-16 |
2023-08-12 |
mouse |
| L Kojic, Q Gu, R M Douglas, M S Cynade. Serotonin facilitates synaptic plasticity in kitten visual cortex: an in vitro study. Brain research. Developmental brain research. vol 101. issue 1-2. 1997-10-01. PMID:9263606. |
serotonergic 5-ht2c receptors are likely to contribute to the synaptic plasticity observed in layer iv, since mesulergine, an antagonist of the 5-ht2c receptor, completely blocked synaptic modifications induced by the combination of low frequency stimulation and serotonin application. |
1997-10-01 |
2023-08-12 |
Not clear |
| D Crespi, M Gobbi, T Mennin. 5-HT3 serotonin hetero-receptors inhibit [3H]acethylcholine release in rat cortical synaptosomes. Pharmacological research. vol 35. issue 4. 1997-09-29. PMID:9264054. |
the present study was designed to verify the presynaptic localization of 5-ht3 serotonin receptors on cholinergic, serotonergic and dopaminergic nerve endings in rat brain regions where they have been shown to modulate the release of these neurotransmitters. |
1997-09-29 |
2023-08-12 |
rat |
| M Z Wrona, Z Yang, F Zhang, G Dryhurs. Potential new insights into the molecular mechanisms of methamphetamine-induced neurodegeneration. NIDA research monograph. vol 173. 1997-09-18. PMID:9260188. |
formation within serotonergic axon terminals, the resultant oxidation of 5-ht would be expected to generate not only 5,6-dht but also t-4,5-d, 7-s-glu-t-4,5-d, 6, 8, and 7,7'-d (figure 1), at least three of which (t-4,5-d, 7-s-glu-t-4,5-d, and 6) are lethal in mouse brain. |
1997-09-18 |
2023-08-12 |
mouse |
| M Z Wrona, Z Yang, F Zhang, G Dryhurs. Potential new insights into the molecular mechanisms of methamphetamine-induced neurodegeneration. NIDA research monograph. vol 173. 1997-09-18. PMID:9260188. |
together these putative aberrant oxidative metabolites of 5-ht and ho.-forming reactions might contribute to the degeneration of serotonergic nerve terminals. |
1997-09-18 |
2023-08-12 |
mouse |
| M Z Wrona, Z Yang, F Zhang, G Dryhurs. Potential new insights into the molecular mechanisms of methamphetamine-induced neurodegeneration. NIDA research monograph. vol 173. 1997-09-18. PMID:9260188. |
similarly, aberrant metabolite(s) of 5-ht (other than or in addition to 5,6-dht) might be involved in the degeneration of serotonergic and dopaminergic terminals and a subpopulation of cell bodies in the somatosensory cortex. |
1997-09-18 |
2023-08-12 |
mouse |
| M Z Wrona, Z Yang, F Zhang, G Dryhurs. Potential new insights into the molecular mechanisms of methamphetamine-induced neurodegeneration. NIDA research monograph. vol 173. 1997-09-18. PMID:9260188. |
thus, it will be of considerable interest to investigate the neurotoxicity of putative aberrant oxidative metabolites of 5-ht (figures 1 and 2) and da (figures 4 and 5) towards serotonergic, dopaminergic, and other neuronal systems and their interactions with nmda, gaba, and other brain receptors. |
1997-09-18 |
2023-08-12 |
mouse |
| S Marracci, D Cini, I Nard. Cloning and developmental expression of 5-HT1A receptor gene in Xenopus laevis. Brain research. Molecular brain research. vol 47. issue 1-2. 1997-09-17. PMID:9221903. |
on the whole, our data show that the x5-ht1a receptor mrna is developmentally regulated, with expression first appearing in differentiating serotonergic neurons, where this receptor may mediate, through an autocrine regulatory pathway, the trophic action of serotonin on developing serotonergic system. |
1997-09-17 |
2023-08-12 |
human |
| G Brüning, O Liangos, H G Baumgarte. Prenatal development of the serotonin transporter in mouse brain. Cell and tissue research. vol 289. issue 2. 1997-09-16. PMID:9211824. |
these results suggest that serotonergic fibers have the equipment to engage in transmitter reuptake long before synapse formation, and that transporter expression might represent a prerequesite for the developmental functions exerted by serotonin. |
1997-09-16 |
2023-08-12 |
mouse |
| S E Hilton, H Maradit, H J Mölle. Serotonin syndrome and drug combinations: focus on MAOI and RIMA. European archives of psychiatry and clinical neuroscience. vol 247. issue 3. 1997-09-15. PMID:9224903. |
we conclude that a spectrum of serotonergic hyperactivity, through to a defined serotonin syndrome, may arise from the use or combination of any serotomimetic substance, as this is a consequence of the mechanism involved, rather than the use of any specific product such as the new antidepressants. |
1997-09-15 |
2023-08-12 |
Not clear |
| S E Hilton, H Maradit, H J Mölle. Serotonin syndrome and drug combinations: focus on MAOI and RIMA. European archives of psychiatry and clinical neuroscience. vol 247. issue 3. 1997-09-15. PMID:9224903. |
given that a spectrum of serotonergic hyperactivity was observed, this analysis prompts redefinition of the currently accepted criteria for serotonin syndrome. |
1997-09-15 |
2023-08-12 |
Not clear |
| A Newman-Tancredi, C Conte, C Chaput, L Verrièle, M J Milla. Agonist and inverse agonist efficacy at human recombinant serotonin 5-HT1A receptors as a function of receptor:G-protein stoichiometry. Neuropharmacology. vol 36. issue 4-5. 1997-09-15. PMID:9225269. |
the serotonergic agonist, eltoprazine, behaved as a partial agonist (emax = 52.7%) at rglow membranes but virtually as a full agonist (emax = 93.2%) at rghigh membranes, relative to 5-ht (= 100%). |
1997-09-15 |
2023-08-12 |
human |
| J Sprouse, L Reynolds, H Rollem. Do 5-HT1B/1D autoreceptors modulate dorsal raphe cell firing? In vivo electrophysiological studies in guinea pigs with GR127935. Neuropharmacology. vol 36. issue 4-5. 1997-09-15. PMID:9225281. |
gr127935 is a selective antagonist of release-modulating 5-ht1b/1d autoreceptors on serotonergic terminals and, as such, would be expected to produce increases in extracellular 5-ht. |
1997-09-15 |
2023-08-12 |
Not clear |
| S A Barma. Pulmonary vasoreactivity to serotonin during hypoxia is modulated by ATP-sensitive potassium channels. Journal of applied physiology (Bethesda, Md. : 1985). vol 83. issue 2. 1997-09-15. PMID:9262454. |
under normoxia, the atp-sensitive k+-channel opener cromakalim (10(-5) m) inhibited the serotonergic response on postcapillary resistance and microvascular compliance, whereas during hypoxia cromakalim inhibited the potentiated effect of serotonin on both precapillary and postcapillary resistance, capillary pressure, and both microvascular and large-vessel compliances. |
1997-09-15 |
2023-08-12 |
dog |