| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J M Lauder, J Liu, D R Grayso. In utero exposure to serotonergic drugs alters neonatal expression of 5-HT(1A) receptor transcripts: a quantitative RT-PCR study. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 2-3. 2000-04-28. PMID:10715571. |
in utero exposure to serotonergic drugs alters neonatal expression of 5-ht(1a) receptor transcripts: a quantitative rt-pcr study. |
2000-04-28 |
2023-08-12 |
rat |
| J M Lauder, J Liu, D R Grayso. In utero exposure to serotonergic drugs alters neonatal expression of 5-HT(1A) receptor transcripts: a quantitative RT-PCR study. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 18. issue 2-3. 2000-04-28. PMID:10715571. |
whatever the mechanism, reductions in 5-ht(1a) receptor transcripts following in utero exposure to serotonergic drugs could significantly impact the number of 5-ht(1a) receptors expressed in neonatal rat brain. |
2000-04-28 |
2023-08-12 |
rat |
| M Kalia, J P O'Callaghan, D B Miller, M Krame. Comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700602. |
comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry. |
2000-04-25 |
2023-08-12 |
rat |
| M Kalia, J P O'Callaghan, D B Miller, M Krame. Comparative study of fluoxetine, sibutramine, sertraline and dexfenfluramine on the morphology of serotonergic nerve terminals using serotonin immunohistochemistry. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700602. |
fluoxetine, sibutramine and sertraline treatment resulted in no depletion of brain serotonin but produced morphological abnormalities in the serotonergic immunoreactive nerve network. |
2000-04-25 |
2023-08-12 |
rat |
| B Ahlemeyer, H Beier, I Semkova, C Schaper, J Krieglstei. S-100beta protects cultured neurons against glutamate- and staurosporine-induced damage and is involved in the antiapoptotic action of the 5 HT(1A)-receptor agonist, Bay x 3702. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700604. |
prehn, m. welsch, c. backhauss, j. nuglisch, f. ausmeier, c. karkoutly, j. krieglstein, effects of serotonergic drugs in experimental brain ischemia: evidence for a protective role of serotonin in cerebral ischemia, brain res. |
2000-04-25 |
2023-08-12 |
rat |
| B Ahlemeyer, H Beier, I Semkova, C Schaper, J Krieglstei. S-100beta protects cultured neurons against glutamate- and staurosporine-induced damage and is involved in the antiapoptotic action of the 5 HT(1A)-receptor agonist, Bay x 3702. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700604. |
azmitia, stimulation of astroglial 5-ht(1a) receptors releases the serotonergic growth factor, protein s-100, and alters astroglial morphology, brain res. |
2000-04-25 |
2023-08-12 |
rat |
| O Massot, B Grimaldi, J M Bailly, M Kochanek, F Deschamps, J Lambrozo, G Fillio. Magnetic field desensitizes 5-HT(1B) receptor in brain: pharmacological and functional studies. Brain research. vol 858. issue 1. 2000-04-25. PMID:10700607. |
the physiological manifestations described lead us to postulate that these symptoms might be related to a dysfunction of the serotonergic system and particularly of the 5-ht(1b) receptors. |
2000-04-25 |
2023-08-12 |
human |
| L A Brotto, B B Gorzalk. Melatonin enhances sexual behavior in the male rat. Physiology & behavior. vol 68. issue 4. 2000-04-25. PMID:10713287. |
moreover, because of the established inverse relationship between male sexual behavior and serotonergic type 2a (5-ht(2a)) receptor activity, "wet-dog shakes" (wds), a 5-ht(2a) receptor mediated behavior, were measured concurrently. |
2000-04-25 |
2023-08-12 |
rat |
| L A Brotto, B B Gorzalk. Melatonin enhances sexual behavior in the male rat. Physiology & behavior. vol 68. issue 4. 2000-04-25. PMID:10713287. |
in addition, there was a consistent, progressive reduction in the frequency of wds, suggestive of a temporal decrement in serotonergic receptor activity and supportive of previous indications that melatonin possesses 5-ht(2a) antagonistic properties. |
2000-04-25 |
2023-08-12 |
rat |
| O M Youngren, G R Pitts, Y Chaiseha, M E El Halawan. An opioid pathway in the hypothalamus of the turkey that stimulates prolactin secretion. Neuroendocrinology. vol 70. issue 5. 2000-04-14. PMID:10567857. |
these data show that: (1) dynorphin stimulates prl secretion by activating kappa opioid receptors in the avian hypothalamus, and (2) dynorphin, 5-ht, da, and vip stimulate avian prl secretion via a common pathway expressing kappa opioid, serotonergic, dopaminergic, and vipergic receptors at synapses arranged serially in that functional order, with the vipergic system as the final mediator (releasing factor). |
2000-04-14 |
2023-08-12 |
Not clear |
| R Seidl, S T Kaehler, H Prast, N Singewald, N Cairns, M Gratzer, G Lube. Serotonin (5-HT) in brains of adult patients with Down syndrome. Journal of neural transmission. Supplementum. vol 57. 2000-04-12. PMID:10666678. |
as the serotonergic system plays a well known role in integrating emotion, cognition and motor function, serotonin (5-ht) and its main metabolite, 5-hydroxyindol-3-acetic acid (5-hiaa) were investigated in post-mortem tissue samples from temporal cortex, thalamus, caudate nucleus, occipital cortex and cerebellum of adult patients with ds, alzheimer's disease (ad) and controls by use of high performance liquid chromatography (hplc). |
2000-04-12 |
2023-08-12 |
Not clear |
| G Battaglia, T M Cabrera-Vera, L D Van De Ka. Prenatal cocaine exposure potentiates 5-HT(2a) receptor function in male and female rat offspring. Synapse (New York, N.Y.). vol 35. issue 3. 2000-04-11. PMID:10657023. |
we have reported previously prenatal cocaine-induced functional deficits in serotonergic terminals, and gender-specific supersensitivity of postsynaptic 5-ht(1a) receptor-mediated hormone responses in offspring. |
2000-04-11 |
2023-08-12 |
rat |
| U Knigge, P Søe-Jensen, H Jorgensen, A Kjaer, M Møller, J Warber. Stress-induced release of anterior pituitary hormones: effect of H3 receptor-mediated inhibition of histaminergic activity or posterior hypothalamic lesion. Neuroendocrinology. vol 69. issue 1. 2000-03-31. PMID:9892850. |
in addition, posterior hypothalamic lesion inhibited the prl response but not the acth and beta-end responses to activation of serotonergic neurons induced by ip administration of the 5-ht precusor 5-hydroxytryptophan in combination with the 5-ht re-uptake inhibitor fluoxetine. |
2000-03-31 |
2023-08-12 |
rat |
| A H Swiergiel, A J Dun. Lack of evidence for a role of serotonin in interleukin-1-induced hypophagia. Pharmacology, biochemistry, and behavior. vol 65. issue 3. 2000-03-27. PMID:10683495. |
the 5-ht(1a) agonists (8-oh-dpat and ipsapirone) and a 5-ht(1b) agonist (cgs12066b) known to decrease the activity of serotonergic neurons, also had no effect. |
2000-03-27 |
2023-08-12 |
mouse |
| I D Hentall, P J Kurle, T R Whit. Correlations between serotonin level and single-cell firing in the rat's nucleus raphe magnus. Neuroscience. vol 95. issue 4. 2000-03-21. PMID:10682715. |
iontophoresis of +/- propranolol, whose serotonergic actions include antagonism and partial agonism at 5-ht1 receptors, also increased serotonin and decreased firing (n=4). |
2000-03-21 |
2023-08-12 |
rat |
| I D Hentall, P J Kurle, T R Whit. Correlations between serotonin level and single-cell firing in the rat's nucleus raphe magnus. Neuroscience. vol 95. issue 4. 2000-03-21. PMID:10682715. |
methiothepin (intravenous, 1 mg/kg), whose serotonergic actions include 5-ht1 and 5-ht2 antagonism, typically raised serotonin levels (four of five cells) and always blocked inhibition by clomipramine (n = 3). |
2000-03-21 |
2023-08-12 |
rat |
| I D Hentall, P J Kurle, T R Whit. Correlations between serotonin level and single-cell firing in the rat's nucleus raphe magnus. Neuroscience. vol 95. issue 4. 2000-03-21. PMID:10682715. |
the released serotonin could contribute to the inhibition of off(m) cells and excitation of on(m) cells by noxious stimulation, since inhibitory 5-ht1a receptors and excitatory 5-ht2 receptors, respectively, have previously been shown to dominate their serotonergic responses. |
2000-03-21 |
2023-08-12 |
rat |
| D Hranilovic, S G Schwab, B Jernej, M Knapp, B Lerer, M Albus, M Rietschel, K Kanyas, M Borrmann, D Lichtermann, W Maier, D B Wildenaue. Serotonin transporter gene and schizophrenia: evidence for association/linkage disequilibrium in families with affected siblings. Molecular psychiatry. vol 5. issue 1. 2000-03-17. PMID:10673774. |
the serotonergic (5-ht) system has been implicated in the etiopathogenesis of psychoses. |
2000-03-17 |
2023-08-12 |
Not clear |
| T Zhou, D J Rademacher, R E Steinpreis, J S Wei. Neurotransmitter levels in two populations of larval Fundulus heteroclitus after methylmercury exposure. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. vol 124. issue 3. 2000-03-14. PMID:10661721. |
a significant increase in da and 5-ht, as well as depressed dopaminergic and serotonergic activity (i.e. |
2000-03-14 |
2023-08-12 |
Not clear |
| T Zhou, D J Rademacher, R E Steinpreis, J S Wei. Neurotransmitter levels in two populations of larval Fundulus heteroclitus after methylmercury exposure. Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology. vol 124. issue 3. 2000-03-14. PMID:10661721. |
exposure of pc larvae to 10 microg/l mehg reduced 5-ht at 14 dph, increased serotonergic activity at 7 dph, and altered dopaminergic activity (i.e. |
2000-03-14 |
2023-08-12 |
Not clear |