| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Gobert, J M Rivet, F Lejeune, A Newman-Tancredi, A Adhumeau-Auclair, J P Nicolas, L Cistarelli, C Melon, M J Milla. Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat. Synapse (New York, N.Y.). vol 36. issue 3. 2000-06-06. PMID:10819900. |
the present study evaluated, via a combined electrophysiological and dialysis approach, the potential influence of serotonin (5-ht)(2c) as compared to 5-ht(2a) and 5-ht(2b) receptors on dopaminergic, adrenergic, and serotonergic transmission in frontal cortex (fcx). |
2000-06-06 |
2023-08-12 |
rat |
| A Gobert, J M Rivet, F Lejeune, A Newman-Tancredi, A Adhumeau-Auclair, J P Nicolas, L Cistarelli, C Melon, M J Milla. Serotonin(2C) receptors tonically suppress the activity of mesocortical dopaminergic and adrenergic, but not serotonergic, pathways: a combined dialysis and electrophysiological analysis in the rat. Synapse (New York, N.Y.). vol 36. issue 3. 2000-06-06. PMID:10819900. |
frontocortical adrenergic, but not serotonergic, transmission is also tonically suppressed by 5-ht(2c) receptors. |
2000-06-06 |
2023-08-12 |
rat |
| D Frechilla, R Insausti, P Ruiz-Golvano, A García-Osta, M P Rubio, J M Almendral, J Del Rí. Implanted BDNF-producing fibroblasts prevent neurotoxin-induced serotonergic denervation in the rat striatum. Brain research. Molecular brain research. vol 76. issue 2. 2000-06-05. PMID:10762706. |
after a survival period of 1 week, the serotonergic innervation of the striatum was assessed by measuring serotonin (5-ht) content and by immunohistochemical detection of 5-ht positive fibers. |
2000-06-05 |
2023-08-12 |
human |
| M T Abellán, T Jolas, G K Aghajanian, F Artiga. Dual control of dorsal raphe serotonergic neurons by GABA(B) receptors. Electrophysiological and microdialysis studies. Synapse (New York, N.Y.). vol 36. issue 1. 2000-06-02. PMID:10700023. |
we assessed the role of gaba(b) receptors in the control of serotonergic (5-ht) neurons of the dorsal raphe nucleus (drn) by using microdialysis in vivo and intra- and extracellular recording in vitro in the rat. |
2000-06-02 |
2023-08-12 |
rat |
| F J Mackay, N R Dunn, R D Man. Antidepressants and the serotonin syndrome in general practice. The British journal of general practice : the journal of the Royal College of General Practitioners. vol 49. issue 448. 2000-05-31. PMID:10818650. |
as a consequence of the greater use of agents affecting the serotonergic system, a syndrome of serotonin hyperstimulation has been recognized more frequently. |
2000-05-31 |
2023-08-12 |
Not clear |
| L Cervo, E Mocaër, A Bertaglia, R Samani. Roles of 5-HT(1A) receptors in the dorsal raphe and dorsal hippocampus in anxiety assessed by the behavioral effects of 8-OH-DPAT and S 15535 in a modified Geller-Seifter conflict model. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727714. |
these results are compatible with the hypothesis that 5-ht(1a) receptor agonists and partial agonists attenuate anxiety by reducing serotonergic transmission in brain areas innervated by the dorsal raphe nucleus. |
2000-05-25 |
2023-08-12 |
Not clear |
| G Lucas, P De Deurwaerdère, S Caccia, Umberto Spampinat. The effect of serotonergic agents on haloperidol-induced striatal dopamine release in vivo: opposite role of 5-HT(2A) and 5-HT(2C) receptor subtypes and significance of the haloperidol dose used. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727716. |
the effect of serotonergic agents on haloperidol-induced striatal dopamine release in vivo: opposite role of 5-ht(2a) and 5-ht(2c) receptor subtypes and significance of the haloperidol dose used. |
2000-05-25 |
2023-08-12 |
rat |
| C Vilpoux, I Leroux-Nicollet, L Naudon, R Raisman-Vozari, J Costenti. Reserpine or chronic paroxetine treatments do not modify the vesicular monoamine transporter 2 expression in serotonin-containing regions of the rat brain. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727718. |
the expression of the vesicular monoamine transporter 2 (vmat2) has been studied in the serotonergic system of the rat brain after an 18 day treatment with the serotonin selective-reuptake inhibitor paroxetine (10 mg/kg, i.p., once daily). |
2000-05-25 |
2023-08-12 |
rat |
| C Vilpoux, I Leroux-Nicollet, L Naudon, R Raisman-Vozari, J Costenti. Reserpine or chronic paroxetine treatments do not modify the vesicular monoamine transporter 2 expression in serotonin-containing regions of the rat brain. Neuropharmacology. vol 39. issue 6. 2000-05-25. PMID:10727718. |
it is concluded that neither a reduction (reserpine) nor an enhancement (paroxetine) of the serotonin transmission induces vmat2 regulation in serotonergic system in the rat brain. |
2000-05-25 |
2023-08-12 |
rat |
| T Rinne, H G Westenberg, J A den Boer, W van den Brin. Serotonergic blunting to meta-chlorophenylpiperazine (m-CPP) highly correlates with sustained childhood abuse in impulsive and autoaggressive female borderline patients. Biological psychiatry. vol 47. issue 6. 2000-05-16. PMID:10715361. |
disturbances of affect, impulse regulation, and autoaggressive behavior, which are all said to be related to an altered function of the central serotonergic (5-ht) system, are prominent features of borderline personality disorder (bpd). |
2000-05-16 |
2023-08-12 |
Not clear |
| J F Cryan, A Harkin, M Naughton, J P Kelly, B E Leonar. Characterization of D-fenfluramine-induced hypothermia: evidence for multiple sites of action. European journal of pharmacology. vol 390. issue 3. 2000-05-11. PMID:10708734. |
depletion of 5-hydroxytryptamine (5-ht) stores following treatment with the serotonergic neurotoxin parachlorophenylalanine reversed the initial hypothermic effects of d-fenfluramine but not the later effects, as d120 min post-challenge) in animals pre-treated with parachlorophenylalanine. |
2000-05-11 |
2023-08-12 |
rat |
| C M Helgason, J L Frank, D R Johnson, M G Frank, S E Hendrick. The effects of St. John's Wort (Hypericum perforatum) on NK cell activity in vitro. Immunopharmacology. vol 46. issue 3. 2000-05-11. PMID:10741904. |
h. perforatum possesses serotonergic properties such as inhibition of serotonin (5-hydroxytryptamine; 5-ht) reuptake. |
2000-05-11 |
2023-08-12 |
Not clear |
| M J Duncan, C J Crafton, D L Wheele. Aging regulates 5-HT(1B) receptors and serotonin reuptake sites in the SCN. Brain research. vol 856. issue 1-2. 2000-05-10. PMID:10677628. |
previous studies have shown that experimentally induced decreases in serotonergic neurotransmission increase 5-ht(1b) receptors but decrease serotonin reuptake sites. |
2000-05-10 |
2023-08-12 |
Not clear |
| M Hansenne, W Pitchot, E Pinto, P Papart, M Anssea. Serotonergic-1a activity and contingent negative variation. Biological psychology. vol 52. issue 3. 2000-05-10. PMID:10725568. |
therefore, the relationship between cnv and serotonergic activity as reflected by prolactin (prl) response to flesinoxan, a 5-ht(1a) full agonist, has been investigated in 28 healthy volunteers. |
2000-05-10 |
2023-08-12 |
human |
| A Laviano, C Cangiano, A Fava, M Muscaritoli, G Mulieri, F Rossi Fanell. Peripherally injected IL-1 induces anorexia and increases brain tryptophan concentrations. Advances in experimental medicine and biology. vol 467. 2000-05-09. PMID:10721046. |
by inference, we conclude that interleukin-1 induced anorexia is mediated by at least two different mechanism: i) interleukin-1 direct action within the hypothalamus; ii) increased brain serotonergic activity, secondary to interleukin-1 induced increased brain availability of the serotonin precursor, tryptophan. |
2000-05-09 |
2023-08-12 |
Not clear |
| S Mouillet-Richard, V Mutel, S Loric, C Tournois, J M Launay, O Kellerman. Regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation. The Journal of biological chemistry. vol 275. issue 13. 2000-05-04. PMID:10734054. |
upon appropriate induction, 100% of 1c11 precursor cells develop neurite extensions and acquire neuronal markers (n-cam, synaptophysin, gammagamma-enolase, and neurofilament) as well as the general functions of either serotonergic (1c11*(/5ht)) (5ht, 5-hydroxytryptamine) or noradrenergic (1c11**(/ne)) (ne, norepinephrine) neurons. |
2000-05-04 |
2023-08-12 |
Not clear |
| S Mouillet-Richard, V Mutel, S Loric, C Tournois, J M Launay, O Kellerman. Regulation by neurotransmitter receptors of serotonergic or catecholaminergic neuronal cell differentiation. The Journal of biological chemistry. vol 275. issue 13. 2000-05-04. PMID:10734054. |
1c11*(/5ht) cells implement a functional 5-ht transporter and thereby a complete serotonergic phenotype within 4 days, whereas 5-ht(1b/d), 5-ht(2b), and 5-ht(2a) receptors are sequentially induced. |
2000-05-04 |
2023-08-12 |
Not clear |
| P Manivet, S Mouillet-Richard, J Callebert, C G Nebigil, L Maroteaux, S Hosoda, O Kellermann, J M Launa. PDZ-dependent activation of nitric-oxide synthases by the serotonin 2B receptor. The Journal of biological chemistry. vol 275. issue 13. 2000-05-04. PMID:10734074. |
in the 1c11 serotonergic cell line and mastomys natalensis carcinoid cells, which naturally express the 5-ht(2b) receptor, as well as in transfected lmtk(-) fibroblasts, stimulation of the 5-ht(2b) receptor triggers intracellular cgmp production through dual activation of constitutive nitric-oxide synthase (cnos) and inducible nos (inos). |
2000-05-04 |
2023-08-12 |
Not clear |
| M Hansenne, M Anssea. P300 event-related potential and serotonin-1A activity in depression. European psychiatry : the journal of the Association of European Psychiatrists. vol 14. issue 3. 2000-05-02. PMID:10572339. |
since serotonin disturbances seem to play a critical role in depression, the aim of the study was to assess the possible relationships between the p300 event-related brain potential and serotonergic activity in depression. |
2000-05-02 |
2023-08-12 |
Not clear |
| U Rao, P Lutchmansingh, R E Polan. Contribution of development to buspirone effects on REM sleep: a preliminary report. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 22. issue 4. 2000-05-01. PMID:10700663. |
in order to assess whether development influences the regulation of rapid eye movement (rem) sleep by serotonergic (5-ht) systems, the rem sleep responses to the partial 5-ht(1a) agonist, buspirone, were assessed in 14 normal adolescent and adult volunteers. |
2000-05-01 |
2023-08-12 |
human |