| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P T Morgan, R Perrins, P E Lloyd, K R Weis. Intrinsic and extrinsic modulation of a single central pattern generating circuit. Journal of neurophysiology. vol 84. issue 3. 2000-10-03. PMID:10979994. |
extrinsic modulation is mediated by the serotonergic metacerebral cell (mcc) neurons and is mimicked by application of serotonin. |
2000-10-03 |
2023-08-12 |
aplysia |
| J Béïque, C de Montigny, P Blier, G Debonne. Effects of sustained administration of the serotonin and norepinephrine reuptake inhibitor venlafaxine: I. in vivo electrophysiological studies in the rat. Neuropharmacology. vol 39. issue 10. 2000-09-28. PMID:10884561. |
moreover, an enhancement of serotonergic neurotransmission by venlafaxine was only achieved under conditions whereby the desensitization of the terminal 5-ht(1b) autoreceptor is appended to that of the somatodendritic 5-ht(1a) receptor. |
2000-09-28 |
2023-08-12 |
rat |
| K E Goeringer, L Raymon, B K Loga. Postmortem forensic toxicology of trazodone. Journal of forensic sciences. vol 45. issue 4. 2000-09-26. PMID:10914583. |
in the cases reviewed, none were attributed solely to trazodone, although trazodone was frequently present together with other serotonergic drugs, such as the selective serotonin reuptake inhibitors like fluoxetine and sertraline. |
2000-09-26 |
2023-08-12 |
human |
| E M Talley, D A Baylis. Postnatal development of 5-HT(1A) receptor expression in rat somatic motoneurons. Brain research. Developmental brain research. vol 122. issue 1. 2000-09-26. PMID:10915900. |
serotonergic innervation of the hypoglossal nucleus (nxii) was disrupted in neonatal rats by intra-cisternal injection of the serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-dht), and 5-ht(1a) receptor mrna levels in nxii from these rats were assayed at postnatal day 21. |
2000-09-26 |
2023-08-12 |
rat |
| E M Talley, D A Baylis. Postnatal development of 5-HT(1A) receptor expression in rat somatic motoneurons. Brain research. Developmental brain research. vol 122. issue 1. 2000-09-26. PMID:10915900. |
in spite of an almost complete loss of serotonergic fibers in the region, the postnatal decrease in 5-ht(1a) receptor expression by hms still occurred. |
2000-09-26 |
2023-08-12 |
rat |
| E M Talley, D A Baylis. Postnatal development of 5-HT(1A) receptor expression in rat somatic motoneurons. Brain research. Developmental brain research. vol 122. issue 1. 2000-09-26. PMID:10915900. |
thus, neonatal expression of 5-ht(1a) receptors appears to be common to somatic motoneurons, but we found no evidence for changes in serotonergic innervation in influencing this expression, nor did we find evidence for its regulation by peripheral factors. |
2000-09-26 |
2023-08-12 |
rat |
| B Vollmayr, S Keck, F A Henn, P Schlos. Acute stress decreases serotonin transporter mRNA in the raphe pontis but not in other raphe nuclei of the rat. Neuroscience letters. vol 290. issue 2. 2000-09-21. PMID:10936689. |
since this neurotrophin also controls the efficacy of serotonergic neurotransmission, the aim of the current study was to investigate the effect of acute immobilization stress on the expression of serotonin transporter (sert) mrna in the raphe nuclei as a parameter of serotonergic innervation. |
2000-09-21 |
2023-08-12 |
rat |
| M Orosco, C Rouch, K Gerozissi. Activation of hypothalamic insulin by serotonin is the primary event of the insulin-serotonin interaction involved in the control of feeding. Brain research. vol 872. issue 1-2. 2000-09-20. PMID:10924676. |
because of the delay of 5-ht response to insulin, an activation of the serotonergic system would be the causal event acting immediately on insulin, and not the contrary. |
2000-09-20 |
2023-08-12 |
rat |
| L Franke, H J Schewe, B Müller, V Campman, W Kitzrow, R Uebelhack, A Berghöfer, B Müller-Oerlinghause. Serotonergic platelet variables in unmedicated patients suffering from major depression and healthy subjects: relationship between 5HT content and 5HT uptake. Life sciences. vol 67. issue 3. 2000-09-19. PMID:10983874. |
serotonergic platelet variables in unmedicated patients suffering from major depression and healthy subjects: relationship between 5ht content and 5ht uptake. |
2000-09-19 |
2023-08-12 |
human |
| L Franke, H J Schewe, B Müller, V Campman, W Kitzrow, R Uebelhack, A Berghöfer, B Müller-Oerlinghause. Serotonergic platelet variables in unmedicated patients suffering from major depression and healthy subjects: relationship between 5HT content and 5HT uptake. Life sciences. vol 67. issue 3. 2000-09-19. PMID:10983874. |
the status of the serotonergic system, expressed as relationship between 5ht content and uptake efficiency, was very similar in patients and controls in the range of medium net uptake rate. |
2000-09-19 |
2023-08-12 |
human |
| P Boulenguez, S L Peters, S N Mitchell, J Chauveau, J A Gray, M H Josep. Dopamine release in the nucleus accumbens and latent inhibition in the rat following microinjections of a 5-HT1B agonist into the dorsal subiculum: implications for schizophrenia. Journal of psychopharmacology (Oxford, England). vol 12. issue 3. 2000-09-15. PMID:10958252. |
microinjection of a serotonergic 5-ht1b agonist (s-cm-gtnh2, 3 microg/l) into the dorsal subiculum (ds) induced long-lasting increases in dopamine (da; +58%), dihydroxyphenylacetic acid (dopac; +15%) and homovanillic acid (hva; +31%), without changing extracellular levels of the serotonin metabolite 5-hydroxyindoleacetic acid (5-hiaa), measured by microdialysis in freely moving rats in the shell area of the nucleus accumbens (n. acc). |
2000-09-15 |
2023-08-12 |
human |
| S L Liang, J T Pa. An endogenous serotonergic rhythm acting on 5-HT(2A) receptors may be involved in the diurnal changes in tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in female rats. Neuroendocrinology. vol 72. issue 1. 2000-09-14. PMID:10940734. |
an endogenous serotonergic rhythm acting on 5-ht(2a) receptors may be involved in the diurnal changes in tuberoinfundibular dopaminergic neuronal activity and prolactin secretion in female rats. |
2000-09-14 |
2023-08-12 |
rat |
| B D Greenberg, Q Li, F R Lucas, S Hu, L A Sirota, J Benjamin, K P Lesch, D Hamer, D L Murph. Association between the serotonin transporter promoter polymorphism and personality traits in a primarily female population sample. American journal of medical genetics. vol 96. issue 2. 2000-09-06. PMID:10893498. |
the serotonin transporter (5-htt) regulates serotonergic neurotransmission and is thought to influence emotion. |
2000-09-06 |
2023-08-12 |
Not clear |
| K Gentsch, U Heinemann, B Schmitz, J Beh. Fenfluramine blocks low-Mg2+-induced epileptiform activity in rat entorhinal cortex. Epilepsia. vol 41. issue 8. 2000-09-05. PMID:10961615. |
considering that the ec receives a strong serotonergic projection from the raphe nuclei and expresses a high density of serotonin (5-ht) receptors, the effect of the 5-ht-releasing drug fenfluramine (ffa) on epileptiform activity generated in the ec was investigated in an in vitro model of epilepsy. |
2000-09-05 |
2023-08-12 |
rat |
| U D McCann, V Eligulashvili, G A Ricaurt. (+/-)3,4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: clinical studies. Neuropsychobiology. vol 42. issue 1. 2000-08-29. PMID:10867551. |
studies in human mdma users probing for evidence of brain serotonergic neurotoxicity indicate that some mdma users may incur mdma-related 5-ht neural injury and, possibly, functional sequelae. |
2000-08-29 |
2023-08-12 |
human |
| D Galter, K Unsicke. Brain-derived neurotrophic factor and trkB are essential for cAMP-mediated induction of the serotonergic neuronal phenotype. Journal of neuroscience research. vol 61. issue 3. 2000-08-29. PMID:10900076. |
using cultures established from the e14 rat raphe we show here that forskolin (10 microm) increases numbers of neurons expressing tryptophan hydroxylase (tpoh), the key enzyme of serotonin synthesis, and uptake of the false serotonergic transmitter 5, 7-dihydroxytryptamine (5,7-dht). |
2000-08-29 |
2023-08-12 |
rat |
| J S Małyszko, J Małyszko, K Pawlak, D Pawlak, W Buczko, M Myśliwie. Importance of serotonergic mechanisms in the thrombotic complications in hemodialyzed patients treated with erythropoietin. Nephron. vol 84. issue 4. 2000-08-28. PMID:10754406. |
since serotonin is also thought to play a role in the pathogenesis of thrombosis, the aim of the study was to evaluate major components of extrinsic coagulation pathway, markers of endothelial cell injury, lipoprotein (a) and peripheral serotonergic mechanisms during rhuepo therapy in hemodialyzed patients. |
2000-08-28 |
2023-08-12 |
human |
| M L Sipos, R A Bauman, J J Widholm, G J Kan. Behavioral effects Of 8-OH-DPAT in chronically stressed male and female rats. Pharmacology, biochemistry, and behavior. vol 66. issue 2. 2000-08-28. PMID:10880697. |
the present study tested the hypothesis that chronic stress desensitizes serotonergic 5-ht(1a) receptors and alters behavioral changes following 5-ht(1a) agonist administration. |
2000-08-28 |
2023-08-12 |
rat |
| B A De Fanti, D A Gavel, J S Hamilton, B A Horwit. Extracellular hypothalamic serotonin levels after dorsal raphe nuclei stimulation of lean (Fa/Fa) and obese (fa/fa) Zucker rats. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865053. |
these results support the hypothesis that the capacity of midbrain serotonergic neurons to release 5-ht at the mh is reduced in obese zucker rats, consistent with their blunted responsiveness to dietary stimuli and greater energetic efficiency. |
2000-08-25 |
2023-08-12 |
rat |
| M J Duncan, L Jennes, J B Jefferson, M S Brownfiel. Localization of serotonin(5A) receptors in discrete regions of the circadian timing system in the Syrian hamster. Brain research. vol 869. issue 1-2. 2000-08-25. PMID:10865072. |
endogenous serotonin and serotonergic drugs influence many aspects of circadian rhythms, including phase shifts, onset of locomotor activity, and period length and integrity of rhythms during exposure to constant light. |
2000-08-25 |
2023-08-12 |
rat |