| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J F Czachura, K Rasmusse. Effects of acute and chronic administration of fluoxetine on the activity of serotonergic neurons in the dorsal raphe nucleus of the rat. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 3. 2001-01-05. PMID:10997729. |
the gradual recovery of activity of serotonergic neurons following an initial inhibition has been hypothesized to play an important role in the delayed onset of efficacy of selective serotonin reuptake inhibitors. |
2001-01-05 |
2023-08-12 |
rat |
| J Repérant, S Araneda, D Miceli, M Medina, J P Ri. Serotonergic retinopetal projections from the dorsal raphe nucleus in the mouse demonstrated by combined [(3)H] 5-HT retrograde tracing and immunolabeling of endogenous 5-HT. Brain research. vol 878. issue 1-2. 2001-01-04. PMID:10996155. |
serotonergic retinopetal projections from the dorsal raphe nucleus in the mouse demonstrated by combined [(3)h] 5-ht retrograde tracing and immunolabeling of endogenous 5-ht. |
2001-01-04 |
2023-08-12 |
mouse |
| P Moore, H P Landolt, E Seifritz, C Clark, T Bhatti, J Kelsoe, M Rapaport, J C Gilli. Clinical and physiological consequences of rapid tryptophan depletion. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 23. issue 6. 2001-01-04. PMID:11063917. |
its current popularity was stimulated by reports that rtd reversed the antidepressant effects of selective serotonin reuptake inhibitors (ssris) and monoamine oxidase inhibitors (maois) in remitted patients with a history of depression but not in patients treated with antidepressants which promote catecholaminergic rather than serotonergic neurotransmission (such as tricyclic antidepressants or buproprion). |
2001-01-04 |
2023-08-12 |
Not clear |
| P J Kenny, S E File, M J Nea. Evidence for a complex influence of nicotinic acetylcholine receptors on hippocampal serotonin release. Journal of neurochemistry. vol 75. issue 6. 2000-12-28. PMID:11080192. |
the effects of nicotine on 5-hydroxytryptamine (5-ht) release from serotonergic nerve endings in rat dorsal hippocampal slices were studied. |
2000-12-28 |
2023-08-12 |
rat |
| H Ono, O Shirakawa, N Nishiguchi, A Nishimura, H Nushida, Y Ueno, K Maed. Tryptophan hydroxylase gene polymorphisms are not associated with suicide. American journal of medical genetics. vol 96. issue 6. 2000-12-28. PMID:11121198. |
tryptophan hydroxylase (tph), the rate-limiting enzyme in serotonin biosynthesis, is one of the most important regulating factors in the serotonergic system. |
2000-12-28 |
2023-08-12 |
human |
| E Hollander, A Kaplan, A Allen, C Cartwrigh. Pharmacotherapy for obsessive-compulsive disorder. The Psychiatric clinics of North America. vol 23. issue 3. 2000-12-27. PMID:10986733. |
augmentation and monotherapy have been explored with serotonergic enhancers, dopamine and 5-ht antagonists, enhancers of second-messenger systems, and gabaergic agents with varying efficacy. |
2000-12-27 |
2023-08-12 |
Not clear |
| J I De Gobbi, L A De Luca, J V Menan. Serotonergic mechanisms of the lateral parabrachial nucleus on DOCA-induced sodium intake. Brain research. vol 880. issue 1-2. 2000-12-21. PMID:11032997. |
injections of the serotonergic 5ht(2a/2c) receptor agonist doi (5 microg/0,2 microl each site) in the lpbn reduced 1.8% nacl intake (6.8+/-1.7 versus saline: 12.4+/-1. |
2000-12-21 |
2023-08-12 |
rat |
| J Semb. [Clinical significance of selective serotonin reuptake inhibitor (SSRI) in the treatment of depression]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 116. issue 2. 2000-12-13. PMID:10976459. |
since ssri primary acts on the serotonergic system, wide use of this drug has questioned the postulated dichotomy of the biological hypothesis of depression, the so-called serotonin depression or norepinephrine depression. |
2000-12-13 |
2023-08-12 |
Not clear |
| G Bringmann, R Brückner, R Mössner, D Feineis, A Heils, K P Lesc. Effect of 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) on human serotonergic cells. Neurochemical research. vol 25. issue 6. 2000-12-07. PMID:10944002. |
incubation experiments using the human serotonergic cell line jar clearly revealed taclo to significantly reduce serotonin (5-ht) uptake (ic(50) = 59 microm) and to induce a distinct loss of cellular viability at increasing taclo concentrations. |
2000-12-07 |
2023-08-12 |
human |
| G Bringmann, R Brückner, R Mössner, D Feineis, A Heils, K P Lesc. Effect of 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) on human serotonergic cells. Neurochemical research. vol 25. issue 6. 2000-12-07. PMID:10944002. |
in contrast to well-known serotonergic neurotoxins such as amphetamines, however, taclo toxicity is not mediated by the 5-ht transporter (5-htt). |
2000-12-07 |
2023-08-12 |
human |
| D Marazziti, F Muratori, A Cesari, I Masala, S Baroni, G Giannaccini, L Dell'Osso, A Cosenza, P Pfanner, G B Cassan. Increased density of the platelet serotonin transporter in autism. Pharmacopsychiatry. vol 33. issue 5. 2000-12-07. PMID:11071017. |
the presence of the 5-ht transporter in platelets, similar to the same structure located in presynaptic serotonergic neurons, has produced a series of studies aimed at assessing its functionality in this disorder, but the ensuing findings are quite controversial. |
2000-12-07 |
2023-08-12 |
human |
| K Gao, P Maso. Serotonergic Raphe magnus cells that respond to noxious tail heat are not ON or OFF cells. Journal of neurophysiology. vol 84. issue 4. 2000-11-30. PMID:11024064. |
serotonergic cells (n = 150) were identified by physiological criteria in anesthetized rats; 30 of 32 cells tested contained serotonin immunoreactivity. |
2000-11-30 |
2023-08-12 |
rat |
| D R Henderson, G S Mitchel. Short-term modulation of the exercise ventilatory response in goats: effects of 8-OH-DPAT and MPPI. American journal of physiology. Regulatory, integrative and comparative physiology. vol 279. issue 5. 2000-11-30. PMID:11049874. |
although nonspecific effects of 8-oh-dpat cannot be ruled out, impaired stm is consistent with the hypothesis that stm requires active raphe serotonergic neurons and 5-ht release. |
2000-11-30 |
2023-08-12 |
Not clear |
| A Laviano, A Cascino, M Muscaritoli, F Rossi Fanell. [Pathogenetic and therapeutic aspects of secondary anorexia]. Annali italiani di medicina interna : organo ufficiale della Societa italiana di medicina interna. vol 15. issue 3. 2000-11-30. PMID:11059060. |
however, consistent experimental and clinical evidence seems to point to hypothalamic serotonergic system hyperactivity as a preeminent cause; this hyperactivity appears to be triggered by enhanced brain availability of tryptophan, the aminoacid precursor of serotonin. |
2000-11-30 |
2023-08-12 |
Not clear |
| G R Twitchell, G L Hanna, E H Cook, H E Fitzgerald, R A Zucke. Serotonergic function, behavioral disinhibition, and negative affect in children of alcoholics: the moderating effects of puberty. Alcoholism, clinical and experimental research. vol 24. issue 7. 2000-11-28. PMID:10923999. |
serotonergic (5-ht) dysfunction has been implicated in both behavioral disinhibition and negative affect in adults. |
2000-11-28 |
2023-08-12 |
Not clear |
| R M Anthenelli, R A Maxwel. Cigarette smoking decreases the prolactin response to serotonergic stimulation in subgroups of alcoholics and controls. Alcoholism, clinical and experimental research. vol 24. issue 7. 2000-11-28. PMID:10924001. |
the prolactin response to serotonergic stimulation has been used as an index of central nervous system serotonin function. |
2000-11-28 |
2023-08-12 |
Not clear |
| J Zhou, L Iacovitt. Mechanisms governing the differentiation of a serotonergic phenotype in culture. Brain research. vol 877. issue 1. 2000-11-28. PMID:10980241. |
in this study, we explored whether a serotonergic (5-ht) phenotype could be novelly induced in the phenotypically plastic neurons of the developing striatum. |
2000-11-28 |
2023-08-12 |
Not clear |
| E Hollander, J Rose. Impulsivity. Journal of psychopharmacology (Oxford, England). vol 14. issue 2 Suppl 1. 2000-11-16. PMID:10888030. |
the link between serotonergic dysfunction and the pathophysiology of impulsivity is discussed, and studies that examine the efficacy of various selective serotonin reuptake inhibitors and other alternatives in the treatment of impulsive disorders such as pathological gambling, sexual addictions and borderline personality disorder are presented. |
2000-11-16 |
2023-08-12 |
Not clear |
| F Chaoulof. Serotonin, stress and corticoids. Journal of psychopharmacology (Oxford, England). vol 14. issue 2. 2000-11-16. PMID:10890308. |
in addition, our knowledge of the impacts of corticoids on serotonergic systems in these brain areas is also briefly provided to examine whether the hypothalamo-pituitary-adrenal axis may play a role in stress-induced alterations in 5-ht neurotransmission. |
2000-11-16 |
2023-08-12 |
human |
| M Yoshimur. Analgesic mechanism of calcitonin. Journal of bone and mineral metabolism. vol 18. issue 4. 2000-11-15. PMID:10874604. |
this effect of ect was completely abolished by injections of p-chlorophenylalanine (pcpa), an inhibitor of serotonin biosynthesis, suggesting that the serotonergic system may be involved in antinociception. |
2000-11-15 |
2023-08-12 |
rat |