| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Brunelli, M Garcia-Gil, R Mozzachiodi, M Roberto, R Scuri, G Traina, M L Zaccard. Neurotoxic effects of caulerpenyne. Progress in neuro-psychopharmacology & biological psychiatry. vol 24. issue 6. 2001-02-08. PMID:11041536. |
this effect overlaps that one produced by 5ht, but it is not affected by the serotonergic antagonist methysergide. |
2001-02-08 |
2023-08-12 |
Not clear |
| S V Nayak, P Rondé, A D Spier, S C Lummis, R A Nichol. Nicotinic receptors co-localize with 5-HT(3) serotonin receptors on striatal nerve terminals. Neuropharmacology. vol 39. issue 13. 2001-02-08. PMID:11044738. |
the presence of nicotinic and 5-ht(3) receptors on the same presynaptic striatal nerve terminal indicates a convergence of cholinergic and serotonergic systems in the striatum. |
2001-02-08 |
2023-08-12 |
Not clear |
| K P Lesch, U Merschdor. Impulsivity, aggression, and serotonin: a molecular psychobiological perspective. Behavioral sciences & the law. vol 18. issue 5. 2001-02-08. PMID:11113963. |
while formation and integration of multiple neural networks is dependent on the actions of neurotransmitters, such as serotonin (5ht), converging lines of evidence indicate that genetically determined variability in serotonergic gene expression influences complex traits including that of inappropriately aggressive behavior. |
2001-02-08 |
2023-08-12 |
mouse |
| M T Abellán, R Martín-Ruiz, F Artiga. Local modulation of the 5-HT release in the dorsal striatum of the rat: an in vivo microdialysis study. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115735. |
these data suggest that the striatal 5-ht release is influenced by local serotonergic and glutamatergic (but not gabaergic) inputs. |
2001-02-08 |
2023-08-12 |
rat |
| R Mössner, D Albert, A M Persico, T Hennig, D Bengel, B Holtmann, A Schmitt, F Keller, R Simantov, D Murphy, I Seif, J Deckert, K P Lesc. Differential regulation of adenosine A(1) and A(2A) receptors in serotonin transporter and monoamine oxidase A-deficient mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115739. |
the serotonin (5ht) transporter (5htt) removes 5ht from the synaptic cleft and is thus critical to the control of serotonergic neurotransmission. |
2001-02-08 |
2023-08-12 |
mouse |
| R Mössner, D Albert, A M Persico, T Hennig, D Bengel, B Holtmann, A Schmitt, F Keller, R Simantov, D Murphy, I Seif, J Deckert, K P Lesc. Differential regulation of adenosine A(1) and A(2A) receptors in serotonin transporter and monoamine oxidase A-deficient mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115739. |
mice with a targeted inactivation of the 5htt represent a novel and unique tool to study serotonergic system functioning. |
2001-02-08 |
2023-08-12 |
mouse |
| R Mössner, D Albert, A M Persico, T Hennig, D Bengel, B Holtmann, A Schmitt, F Keller, R Simantov, D Murphy, I Seif, J Deckert, K P Lesc. Differential regulation of adenosine A(1) and A(2A) receptors in serotonin transporter and monoamine oxidase A-deficient mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115739. |
a comparison of 5htt knockout versus control mice revealed upregulation of a(1) receptors in the dorsal raphe nucleus (drn, +21%), but not in any of the serotonergic projection areas, and downregulation of a(2a) receptors in basal ganglia. |
2001-02-08 |
2023-08-12 |
mouse |
| K Koed, K Linne. Opposing changes in serotonin and norepinephrine transporter mRNA levels after serotonin depletion. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 10. issue 6. 2001-02-08. PMID:11115741. |
we have now investigated the expression of both the 5htt and the norepinephrine transporter (net) gene to assess the possible interaction between the noradrenergic and the serotonergic neurotransmitter systems. |
2001-02-08 |
2023-08-12 |
Not clear |
| C Roberts, P Hatcher, J J Hagan, N E Austin, P Jeffrey, P Wyman, L M Gaster, C Routledge, D N Middlemis. The effect of SB-236057-A, a selective 5-HT1B receptor inverse agonist, on in vivo extracellular 5-HT levels in the freely-moving guinea-pig. Naunyn-Schmiedeberg's archives of pharmacology. vol 362. issue 2. 2001-02-02. PMID:10961381. |
5-ht1b autoreceptors are involved in the control of extracellular 5-ht levels from both the terminal and cell body regions of serotonergic neurones. |
2001-02-02 |
2023-08-12 |
Not clear |
| M Collin, M L Håkansson-Ovesjö, I Misane, S O Ogren, B Meiste. Decreased 5-HT transporter mRNA in neurons of the dorsal raphe nucleus and behavioral depression in the obese leptin-deficient ob/ob mouse. Brain research. Molecular brain research. vol 81. issue 1-2. 2001-02-01. PMID:11000478. |
taken together, these results suggest that serotonergic cell bodies in the rodent dorsal raphe nucleus possess leptin receptors and that the serotonergic system, as reflected by expression levels of 5-ht transporter mrna, is down-regulated in the obese behaviorally depressed ob/ob mouse. |
2001-02-01 |
2023-08-12 |
mouse |
| R B Rothman, M H Baumann, J E Savage, L Rauser, A McBride, S J Hufeisen, B L Rot. Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. Circulation. vol 102. issue 23. 2001-02-01. PMID:11104741. |
evidence for possible involvement of 5-ht(2b) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. |
2001-02-01 |
2023-08-12 |
Not clear |
| M Berk, D J Stein, A Potgieter, C M Maud, C Els, M L Janet, E Viljoe. Serotonergic targets in the treatment of antidepressant induced sexual dysfunction: a pilot study of granisetron and sumatriptan. International clinical psychopharmacology. vol 15. issue 5. 2001-01-18. PMID:10993131. |
while there is some evidence of involvement of the serotonin (5-ht2) receptor subtype in this phenomenon, other serotonergic receptor systems are not well studied. |
2001-01-18 |
2023-08-12 |
Not clear |
| L N Yatham, M Steiner, P F Liddle, I S Shiah, R W Lam, A P Zis, M Coot. A PET study of brain 5-HT2 receptors and their correlation with platelet 5-HT2 receptors in healthy humans. Psychopharmacology. vol 151. issue 4. 2001-01-18. PMID:11026749. |
platelets share many properties with brain serotonergic neurons such as active 5-hydroxytryptamine (5-ht) transport, 5-ht2 receptors, and mitochondrial monoamine oxidase. |
2001-01-18 |
2023-08-12 |
Not clear |
| C A Marsden, S C Stanfor. CNS drugs III: psychotherapeutics. Expert opinion on investigational drugs. vol 9. issue 8. 2001-01-18. PMID:11203476. |
the main areas covered were how serotonergic ligands could he used with greater effect in depression and schizophrenia, the therapeutic value of serotonin noradrenaline uptake inhibitors (snris) and the potential clinical value of new amine re-uptake inhibitors. |
2001-01-18 |
2023-08-12 |
Not clear |
| H H Berendse. The role of serotonin in hot flushes. Maturitas. vol 36. issue 3. 2001-01-16. PMID:11063896. |
surprisingly, apart from treatment with some selective serotonin (5-ht) reuptake inhibitors (ssri's), up till now, little attention is given to the strong interaction of estrogens with the serotonergic system. |
2001-01-16 |
2023-08-12 |
Not clear |
| I A Chistopolsky, D A Sakharo. Activation of serotonergic neurons by the metabolic precursor of serotonin: the effect of a tryptophan decarboxylase inhibitor. Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections. vol 372. 2001-01-11. PMID:10944710. |
activation of serotonergic neurons by the metabolic precursor of serotonin: the effect of a tryptophan decarboxylase inhibitor. |
2001-01-11 |
2023-08-12 |
Not clear |
| C J Hawley, P J Loughlin, S J Quick, T M Gale, T Sivakumaran, J Hayes, S McPhe. Efficacy, safety and tolerability of combined administration of lithium and selective serotonin reuptake inhibitors: a review of the current evidence. Hertfordshire Neuroscience Research Group. International clinical psychopharmacology. vol 15. issue 4. 2001-01-11. PMID:10954059. |
several case reports have engendered concern about the safety of coadministering lithium and selective serotonin reuptake inhibitor (ssri) antidepressants and there are theoretical reasons to suppose that lithium and serotonergic antidepressants may be associated with dangerous interactions. |
2001-01-11 |
2023-08-12 |
Not clear |
| U Bailer, P Fischer, B Küfferle, J Stastny, S Kaspe. Occurrence of mirtazapine-induced delirium in organic brain disorder. International clinical psychopharmacology. vol 15. issue 4. 2001-01-11. PMID:10954066. |
its antidepressant effect appears to be related to its dual enhancement of both noradrenergic neurotransmission and serotonin 5-ht1 receptor-mediated serotonergic neurotransmission. |
2001-01-11 |
2023-08-12 |
Not clear |
| T Terao, J Nakamura, R Yoshimura, O Ohmori, N Takahashi, H Kojima, S Soeda, T Shinkai, H Nakano, T Okun. Relationship between serum cholesterol levels and meta-chlorophenylpiperazine-induced cortisol responses in healthy men and women. Psychiatry research. vol 96. issue 2. 2001-01-11. PMID:11063789. |
in the human brain, m-cpp binds both to various serotonergic receptors, mainly 5-ht(2c), and to alpha(2)-adrenoceptors. |
2001-01-11 |
2023-08-12 |
human |
| L Uphous. Female gonadal hormones, serotonin, and sexual receptivity. Brain research. Brain research reviews. vol 33. issue 2-3. 2001-01-08. PMID:11011068. |
the inhibitory and facilitatory effect of serotonergic (5-ht) receptor agonists and antagonists on the female rat lordosis reflex is reviewed. |
2001-01-08 |
2023-08-12 |
rat |