| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Ozawa, S Takashim. Developmental neurotransmitter pathology in the brainstem of sudden infant death syndrome: a review and sleep position. Forensic science international. vol 130 Suppl. 2003-01-02. PMID:12350301. |
in sids infants, there are an increase of glial fibrillary acidic protein (gfap)-positive astrocytes in the brainstem, an increase of substance p (sp) in the medulla and pons, a decrease of tyrosine hydroxylase (th)-positive catecholaminergic neurons in the ventrolateral medulla (vlm), and vagal nuclei in the medulla oblongata and basal ganglia, a decrease of tryptophan hydroxylase (trh)-positive serotonergic neurons in the periaqueductal gray matter (pag), and decreases of 5-hydroxytryptamine 1a (5-ht1a) and 5-ht2a receptor immunoreactivities in the vlm and vagal nuclei in the medulla oblongata. |
2003-01-02 |
2023-08-12 |
Not clear |
| Thomas Roskoden, Karl Zilles, Axel Schleicher, Herbert Schwegle. Transient postnatal thyroxine treatment leads to variation in transmitter binding site densities in the hippocampus of rats. Neuroscience letters. vol 333. issue 1. 2002-12-26. PMID:12401551. |
in the adult animals we measured the densities of glutamatergic (n-methyl-d-aspartate (nmda), amino-3-hydroxy-5-methylisoxazole-4-propionic acid (ampa), kainic acid (ka)), cholinergic (muscarinic subtype 1 and 2 (m1, m2)), gamma-aminobutyric acid (gaba)ergic (gaba(a)) and serotonergic (5-hydroxytryptamine (5-ht(1a))) binding sites using quantitative receptor-autoradiography with tritiated ligands. |
2002-12-26 |
2023-08-12 |
rat |
| P Netter, C Toll, C Lujic, M Reuter, J Henni. Addictive and nonaddictive smoking as related to responsivity to neurotransmitter systems. Behavioural pharmacology. vol 13. issue 5-6. 2002-12-23. PMID:12394420. |
nontolerant but addicted subjects exhibited increased serotonergic responsivity, interpreted as resulting from low serotonin levels associated with lack of impulse control. |
2002-12-23 |
2023-08-12 |
human |
| R Zółtowski, R Pawlak, T Matys, M Pietraszek, W Buczk. Propranolol modifies platelet serotonergic mechanisms in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 53. issue 2. 2002-12-20. PMID:12120901. |
because there are evidences supporting a possible involvement of serotonin (5-ht) in the actions of beta-blockers, we studied the effect of propranolol on peripheral serotonergic mechanisms in normotensive and goldblatt two-kidney - one clip (2k1c) hypertensive rats. |
2002-12-20 |
2023-08-12 |
rat |
| M C Austin, R E Whitehead, C L Edgar, J E Janosky, D A Lewi. Localized decrease in serotonin transporter-immunoreactive axons in the prefrontal cortex of depressed subjects committing suicide. Neuroscience. vol 114. issue 3. 2002-12-20. PMID:12220580. |
a variety of postmortem brain studies and clinical investigations have provided evidence that reduced serotonin neurotransmission is associated with suicidal behavior and depression, and several serotonergic parameters have been found to be altered in the prefrontal cortex of suicide victims. |
2002-12-20 |
2023-08-12 |
human |
| P Heiser, H Remschmid. [Selective serotonin reuptake inhibitors and newer antidepressive substances in child and adolescent psychiatry]. Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie. vol 30. issue 3. 2002-12-19. PMID:12227220. |
among these newer groups, characterised by their pharmacological properties, are the serotonin2-antagonists/serotonin reuptake inhibitors (sari), the noradrenergic and specific serotonergic antidepressants (nassa), the noradrenaline and dopamine reuptake inhibitors (ndri) and the serotonin and noradrenaline reuptake inhibitors (snri). |
2002-12-19 |
2023-08-12 |
Not clear |
| L A Dawson, H Q Nguyen, D L Smith, L E Schechte. Effect of chronic fluoxetine and WAY-100635 treatment on serotonergic neurotransmission in the frontal cortex. Journal of psychopharmacology (Oxford, England). vol 16. issue 2. 2002-12-17. PMID:12095073. |
however, fluoxetine alone produced a time-dependent adaptation in serotonergic transmission such that fluoxetine (acutely administered on day 15) was able to produce a two-fold increase in extracellular 5-ht levels but the decrease in response to 8-oh-dpat was completely attenuated. |
2002-12-17 |
2023-08-12 |
Not clear |
| Eitan Gur, Eliyahu Dremencov, Francisca Garcia, Louis D Van de Kar, Bernard Lerer, Michael E Newma. Functional effects of chronic electroconvulsive shock on serotonergic 5-HT(1A) and 5-HT(1B) receptor activity in rat hippocampus and hypothalamus. Brain research. vol 952. issue 1. 2002-12-10. PMID:12363404. |
functional effects of chronic electroconvulsive shock on serotonergic 5-ht(1a) and 5-ht(1b) receptor activity in rat hippocampus and hypothalamus. |
2002-12-10 |
2023-08-12 |
rat |
| Jean-Marc Goaillard, Pierre Vincen. Serotonin suppresses the slow afterhyperpolarization in rat intralaminar and midline thalamic neurones by activating 5-HT(7) receptors. The Journal of physiology. vol 541. issue Pt 2. 2002-12-09. PMID:12042351. |
in vivo recordings have shown that stimulation of the serotonergic raphe nuclei can alter the response of these neurones to a nociceptive stimulus, suggesting that serotonin modulates their firing properties. |
2002-12-09 |
2023-08-12 |
rat |
| C Mulert, G Juckel, H Augustin, U Heger. Comparison between the analysis of the loudness dependency of the auditory N1/P2 component with LORETA and dipole source analysis in the prediction of treatment response to the selective serotonin reuptake inhibitor citalopram in major depression. Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology. vol 113. issue 10. 2002-12-04. PMID:12350432. |
the loudness dependency of the auditory evoked potentials (ldaep) is used as an indicator of the central serotonergic system and predicts clinical response to serotonin agonists. |
2002-12-04 |
2023-08-12 |
Not clear |
| Catherine A Roca, Peter J Schmidt, Mark J Smith, Merry A Danaceau, Dennis L Murphy, David R Rubino. Effects of metergoline on symptoms in women with premenstrual dysphoric disorder. The American journal of psychiatry. vol 159. issue 11. 2002-12-04. PMID:12411222. |
the authors investigated the role of acute serotonergic modulation in the efficacy of selective serotonin reuptake inhibitors (ssris) in women with premenstrual dysphoric disorder. |
2002-12-04 |
2023-08-12 |
Not clear |
| Francesco Cresp. In vivo voltammetry and concomitant electrophysiology at a single micro-biosensor to analyse ischaemia, depression and drug dependence. Journal of neuroscience methods. vol 119. issue 2. 2002-11-26. PMID:12323421. |
original data concerning ascorbate release in ischaemia, peptidergic activity during craving for drugs of abuse and concomitant voltammetric and electrophysiological changes of the serotonergic system in rats submitted to forced swimming test or to pharmacological treatment with the selective serotonin reuptake inhibitor fluoxetine are shown and discussed. |
2002-11-26 |
2023-08-12 |
rat |
| Patricia Ohliger-Frerking, John M Horowitz, Barbara A Horwit. Enhanced adrenergic excitation of serotonergic dorsal raphe neurons in genetically obese rats. Neuroscience letters. vol 332. issue 2. 2002-11-26. PMID:12384222. |
serotonergic neurons in the dorsal raphe nucleus (drn) project to the ventromedial hypothalamus (vmh), where serotonin (5-ht) release modulates feeding. |
2002-11-26 |
2023-08-12 |
human |
| Patricia Ohliger-Frerking, John M Horowitz, Barbara A Horwit. Enhanced adrenergic excitation of serotonergic dorsal raphe neurons in genetically obese rats. Neuroscience letters. vol 332. issue 2. 2002-11-26. PMID:12384222. |
to determine if the difference in 5-ht release between lean and obese rats might be due to differences in these neuromodulatory pathways, we examined the effects of phenylephrine (pe) and 5-ht on serotonergic drn neurons using current-clamp recording. |
2002-11-26 |
2023-08-12 |
human |
| Robert Hoerr, Michael Noeldne. Ensaculin (KA-672 HCl): a multitransmitter approach to dementia treatment. CNS drug reviews. vol 8. issue 2. 2002-11-25. PMID:12177685. |
in receptor-binding studies, ensaculin was found to have high affinities to serotonergic 5-ht(1a) and 5-ht(7) receptors, adrenergic alpha(1), and dopaminergic d(2) and d(3) receptors. |
2002-11-25 |
2023-08-12 |
rat |
| Hitoshi Takahashi, Keizo Yoshida, Kenich Ito, Kazuhiro Sato, Mitsuhiro Kamata, Hisashi Higuchi, Tetsuo Shimizu, Kunihiko Ito, Kazuyuki Inoue, Takehiko Tezuka, Toshio Suzuki, Tadashi Ohkubo, Kazunobu Sugawar. No association between the serotonergic polymorphisms and incidence of nausea induced by fluvoxamine treatment. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 12. issue 5. 2002-11-22. PMID:12208565. |
we investigated the association between serotonergic polymorphisms and incidence of nausea, which is the most frequent side-effect of selective serotonin reuptake inhibiters (ssris), in 66 patients treated with fluvoxamine in a protocolized-dosing method. |
2002-11-22 |
2023-08-12 |
Not clear |
| Erica L Unger, Pascale Mazzola-Pomietto, Dennis L Murphy, Anne M Andrew. 2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine]. The Journal of pharmacology and experimental therapeutics. vol 303. issue 2. 2002-11-22. PMID:12388632. |
furthermore, this lower dose of 2'-nh(2)-mptp altered functional serotonin neurotransmission as evidenced by a 2-fold potentiation of 1-(3-chlorophenyl)-piperazine.2hcl-induced hyperthermia, an index of serotonergic denervation supersensitivity. |
2002-11-22 |
2023-08-12 |
mouse |
| Marilyn J Duncan, Julie G Hensle. Aging alters in a region-specific manner serotonin transporter sites and 5-HT(1A) receptor-G protein interactions in hamster brain. Neuropharmacology. vol 43. issue 1. 2002-11-21. PMID:12213257. |
key proteins regulating serotonergic activity, specifically the serotonin transporter and 5-ht(1a) receptor, were examined in the midbrain raphe nuclei of young (3-4 months) and old (17-19 months) hamsters (n=7-10/group). |
2002-11-21 |
2023-08-12 |
Not clear |
| Bartosz Bobula, Agnieszka Zahorodna, Krzysztof Tokarski, Grzegorz Hes. [Use of models for spontaneous paroxysmal activity in studies of adaptive changes in serotonin receptors]. Postepy higieny i medycyny doswiadczalnej. vol 56. issue 3. 2002-11-20. PMID:12194250. |
certain antidepressant medications exert effects on the serotonergic (5-ht) system but their mechanisms are still not well understood. |
2002-11-20 |
2023-08-12 |
Not clear |
| Christian P Müller, Maria A De Souza Silva, Gail DePalma, Carlos Tomaz, Robert J Carey, Joseph P Husto. The selective serotonin(1A)-receptor antagonist WAY 100635 blocks behavioral stimulating effects of cocaine but not ventral striatal dopamine increase. Behavioural brain research. vol 134. issue 1-2. 2002-11-19. PMID:12191821. |
cocaine induced increases in serotonergic (5-ht) activity also appears to be involved in these effects. |
2002-11-19 |
2023-08-12 |
rat |