| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Sevcík, P Petrovický, V Růzicka, J Slánský, K Mase. Structures and pathways of the central nervous system are potentially involved in the serotonergic modulation of gastrointestinal activity. Methods and findings in experimental and clinical pharmacology. vol 24. issue 10. 2003-04-04. PMID:12616959. |
the differences between 5-ht responses of preparations from either sham-operated or experimental rats suggest the existence of brainstem regions (dorsal vagal and solitary nuclei, parvocellular reticular nuclei and serotonergic a1,2,5 groups) that either stimulate or inhibit 5-ht modulatory action in the rat gastrointestinal tract. |
2003-04-04 |
2023-08-12 |
rat |
| Ahmet Uğur Yalcin, Garip Sahin, Mehmet Erol, Cengiz Ba. Sertraline hydrochloride treatment for patients with hemodialysis hypotension. Blood purification. vol 20. issue 2. 2003-04-03. PMID:11818677. |
several studies have shown that central serotonergic pathways participate in the abnormal response, and selective serotonin reuptake inhibitors improve the symptoms of patients with neurocardiogenic syncope or idiopathic orthostatic hypotension. |
2003-04-03 |
2023-08-12 |
Not clear |
| Takehiro Ochi, Yoshitaka Ohkubo, Seitaro Muto. FR143166 attenuates spinal pain transmission through activation of the serotonergic system. European journal of pharmacology. vol 452. issue 3. 2003-04-02. PMID:12359273. |
these results suggest that the descending serotonergic system, especially spinal 5-ht(2a) and 5-ht(3) receptors, is involved in the antinociceptive activity of spinally administered fr143166 on noxious mechanical stimuli. |
2003-04-02 |
2023-08-12 |
mouse |
| Caroline Bell, Sue Wilson, Ann Rich, Jayne Bailey, David Nut. Effects on sleep architecture of pindolol, paroxetine and their combination in healthy volunteers. Psychopharmacology. vol 166. issue 2. 2003-04-02. PMID:12536263. |
animal studies have suggested that this increased response occurs because of 5ht(1a) antagonist properties of pindolol, which in combination with a serotonergic antidepressant produces a synergistic increase in 5ht in the synapse. |
2003-04-02 |
2023-08-12 |
human |
| O Lingjaerd. Effects of various anions on serotonin transport in human platelets. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 1. issue 3. 2003-04-02. PMID:12607223. |
these findings are relevant also for serotonin reuptake at serotonergic synapses, since it has been shown that the serotonin transporter (5htt) in platelets is identical to that in the brain. |
2003-04-02 |
2023-08-12 |
human |
| Jeffrey N Stuart, Xin Zhang, Jennifer A Jakubowski, Elena V Romanova, Jonathan V Sweedle. Serotonin catabolism depends upon location of release: characterization of sulfated and gamma-glutamylated serotonin metabolites in Aplysia californica. Journal of neurochemistry. vol 84. issue 6. 2003-03-28. PMID:12614336. |
initially demonstrated to be in the metacerebral cell (mcc) soma, the new serotonin metabolite serotonin-o-sulfate may contribute to important functions in the serotonergic system beyond simple serotonin inactivation. |
2003-03-28 |
2023-08-12 |
aplysia |
| Didier Cussac, Delphine Duqueyroix, Adrian Newman-Tancredi, Mark J Milla. Stimulation by antipsychotic agents of mitogen-activated protein kinase (MAPK) coupled to cloned, human (h)serotonin (5-HT)(1A) receptors. Psychopharmacology. vol 162. issue 2. 2003-03-26. PMID:12110994. |
there is evidence that serotonergic mechanisms contribute to the functional profiles of antipsychotic drugs, several of which display affinity for human (h)5-ht(1a) receptors. |
2003-03-26 |
2023-08-12 |
human |
| b' Nela Pivac, Dorotea M\\xc3\\xbcck-Seler, Marina Sagud, Miro Jakovljevi\\xc4\\x8. Platelet serotonergic markers in posttraumatic stress disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452545.' |
the data on the role of 5-ht have been obtained using blood platelets as a peripheral model for central serotonergic neurons. |
2003-03-26 |
2023-08-12 |
human |
| b' Nela Pivac, Dorotea M\\xc3\\xbcck-Seler, Marina Sagud, Miro Jakovljevi\\xc4\\x8. Platelet serotonergic markers in posttraumatic stress disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452545.' |
since the data on the peripheral serotonergic markers in ptsd subjects are controversial, the aim of the study was to determine platelet 5-ht concentration and platelet mao activity in war veterans with ptsd, war veterans who did not develop ptsd, and in war veterans who were prisoners of war and developed ptsd. |
2003-03-26 |
2023-08-12 |
human |
| b' Nela Pivac, Dorotea M\\xc3\\xbcck-Seler, Marina Sagud, Miro Jakovljevi\\xc4\\x8. Platelet serotonergic markers in posttraumatic stress disorder. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 6. 2003-03-26. PMID:12452545.' |
these findings suggest that platelet 5-ht concentration and platelet mao activity are not altered in three drug-free groups--war veterans who did or did not develop ptsd, or in prisoners of war with ptsd--and that these platelet serotonergic markers are not associated with symptoms of ptsd or comorbid depression. |
2003-03-26 |
2023-08-12 |
human |
| T S Sperry, C K Thompson, J C Wingfiel. Effects of acute treatment with 8-OH-DPAT and fluoxetine on aggressive behaviour in male song sparrows (Melospiza melodia morphna). Journal of neuroendocrinology. vol 15. issue 2. 2003-03-26. PMID:12535157. |
the role of serotonin in modulating male aggressive behaviour was investigated in male song sparrows, melospiza melodia morphna, using two different serotonergic drugs, fluoxetine and 8-oh-dpat. |
2003-03-26 |
2023-08-12 |
Not clear |
| Kayo Yasuda, Katsuya Suemaru, Hiroaki Araki, Yutaka Gomit. Effect of nicotine cessation on the central serotonergic systems in mice: involvement of 5-HT(2) receptors. Naunyn-Schmiedeberg's archives of pharmacology. vol 366. issue 3. 2003-03-24. PMID:12172711. |
effect of nicotine cessation on the central serotonergic systems in mice: involvement of 5-ht(2) receptors. |
2003-03-24 |
2023-08-12 |
mouse |
| Jean-Chrétien Norreel, Jean-François Pflieger, Edouard Pearlstein, Juliette Simeoni-Alias, François Clarac, Laurent Vina. Reversible disorganization of the locomotor pattern after neonatal spinal cord transection in the rat. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 5. 2003-03-24. PMID:12629197. |
alternation was restored after the activation of serotonergic 5-ht(2) receptors in vivo. |
2003-03-24 |
2023-08-12 |
rat |
| R Klink, M Robichaud, G Debonne. Gender and gonadal status modulation of dorsal raphe nucleus serotonergic neurons. Part I: effects of gender and pregnancy. Neuropharmacology. vol 43. issue 7. 2003-03-21. PMID:12504918. |
the ovarian steroids, estrogen (e) and progesterone (p), may modulate the function of the serotonergic (5-ht) system, implicated in the etiology and treatment of affective disorders. |
2003-03-21 |
2023-08-12 |
rat |
| Analía Bortolozzi, Ricardo Duffard, Ana María Evangelista de Duffar. Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology. vol 24. issue 1. 2003-03-21. PMID:12564390. |
in addition, the increased 5-ht content detected in both the right and left striata observed in this study could be the answer to the behaviors observed and to the early alterations in dopamine in basal ganglia by 2,4-d in neonatal exposed rats, mediated by a serotonergic modulation on the dopaminergic system. |
2003-03-21 |
2023-08-12 |
rat |
| Jordi Riba, Antoni Rodríguez-Fornells, Manel J Barbano. Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively. Psychopharmacology. vol 165. issue 1. 2003-03-20. PMID:12474114. |
contrary to findings in lower animals, unexpected increases in sensorimotor gating have been found in humans following the administration of the serotonergic psychedelic psilocybin and the serotonin releaser 3,4-methylenedioxymethamphetamine (mdma). |
2003-03-20 |
2023-08-12 |
human |
| Suhail Kasim, Kiyoshi Egami, H A Jinna. Self-biting induced by activation of L-type calcium channels in mice: serotonergic influences. Developmental neuroscience. vol 24. issue 4. 2003-03-17. PMID:12457070. |
since the serotonergic systems have been implicated in the expression of self-injurious behavior in both humans and animals, the present studies tested whether drugs influencing serotonin systems could modify the ability of +/-bay k 8644 to cause this behavior. |
2003-03-17 |
2023-08-12 |
mouse |
| Esther Gómez-Gil, Cristóbal Gastó, Maribel Díaz-Ricart, Marta Carretero, Manel Salamero, Rosa Catalán, Ginés Escola. Platelet 5-HT2A-receptor-mediated induction of aggregation is not altered in major depression. Human psychopharmacology. vol 17. issue 8. 2003-03-17. PMID:12457378. |
studies of the 5-ht(2a) receptor subtype in major depression have focused on the density of these receptors in neuronal cells and platelets, showing an up-regulation secondary to a deficit in serotonergic activity in major depression. |
2003-03-17 |
2023-08-12 |
Not clear |
| Gregers Wegener, Vallo Volke, Brian H Harvey, Raben Rosenber. Local, but not systemic, administration of serotonergic antidepressants decreases hippocampal nitric oxide synthase activity. Brain research. vol 959. issue 1. 2003-03-17. PMID:12480166. |
however, since these data reflect effects on basal nos activity, we believe that serotonergic antidepressants do not directly affect nos at dosages used clinically, but the findings may reflect a secondary action of antidepressants on the glutamate nmda receptor following their primary inhibitory action at the 5-ht transporter. |
2003-03-17 |
2023-08-12 |
Not clear |
| Julia Wellsow, Karl-Artur Kovar, Hans-Jürgen Machull. Molecular modeling of potential new and selective PET radiotracers for the serotonin transporter. Positron Emission Tomography. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. vol 5. issue 3. 2003-03-17. PMID:12553893. |
imaging the serotonin transporter (sert) with positron emission tomography (pet) provides a useful tool for understanding alterations of the serotonergic system. |
2003-03-17 |
2023-08-12 |
Not clear |