| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Krzysztof Tokarski, Agnieszka Zahorodna, Bartosz Bobula, Grzegorz Hes. Comparison of the effects of 5-HT1A and 5-HT4 receptor activation on field potentials and epileptiform activity in rat hippocampus. Experimental brain research. vol 147. issue 4. 2003-03-14. PMID:12444482. |
a comparison of the dose-dependence of the excitatory and inhibitory effects of serotonergic agonists on the amplitude of the population spike and on the frequency of epileptiform discharges indicated that the latter is a more sensitive measure of the activation of 5-ht(1a) and 5-ht(4) receptors than the former. |
2003-03-14 |
2023-08-12 |
rat |
| Nicoletta Sonino, Giovanni A Fav. Residual symptoms in depression an emerging therapeutic concept. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 4. 2003-03-12. PMID:12188108. |
since central serotonergic regulation could have a role in the course of cushing's disease, serotonin antagonists (e.g., cyproheptadine, ritanserin and ketanserin) have been employed. |
2003-03-12 |
2023-08-12 |
Not clear |
| Gil Levkowitz, Jörg Zeller, Howard I Sirotkin, Dorothy French, Sarah Schilbach, Hisashi Hashimoto, Masahiko Hibi, William S Talbot, Arnon Rosentha. Zinc finger protein too few controls the development of monoaminergic neurons. Nature neuroscience. vol 6. issue 1. 2003-03-07. PMID:12469125. |
the mechanism controlling the development of dopaminergic (da) and serotonergic (5ht) neurons in vertebrates is not well understood. |
2003-03-07 |
2023-08-12 |
zebrafish |
| Anja Birthelmer, Theresa Schweizer, Hélène Jeltsch, Rolf Jackisch, Jean-Christophe Casse. 5,7-Dihydroxytryptamine lesions enhance and serotonergic grafts normalize the evoked overflow of acetylcholine in rat hippocampal slices. The European journal of neuroscience. vol 16. issue 10. 2003-03-05. PMID:12453047. |
the lesion-induced reduction of the 5-ht1b autoreceptor-mediated inhibition of evoked 5-ht release may be an adaptation enhancing serotonergic transmission in the (few) remaining terminals. |
2003-03-05 |
2023-08-12 |
rat |
| Janusz Szyndler, Paulina Rok, Piotr Maciejak, Jerzy Walkowiak, Agnieszka I Członkowska, Halina Sienkiewicz-Jarosz, Aleksandra Wisłowska, Małgorzata Zienowicz, Małgorzata Lehner, Andrzej Bidziński, Wojciech Kostowski, Adam Plazni. Effects of pentylenetetrazol-induced kindling of seizures on rat emotional behavior and brain monoaminergic systems. Pharmacology, biochemistry, and behavior. vol 73. issue 4. 2003-03-04. PMID:12213531. |
the hypothesis is put forward that ptz kindling-induced inhibition of the serotonergic innervation may lead to the compensatory increase in 5-ht(1a) receptors in the dentate gyrus of the hippocampus, thus evoking the anxiolytic-like changes in animal behavior. |
2003-03-04 |
2023-08-12 |
rat |
| Fumihiko Yasuno, Tetsuya Suhara, Takashi Nakayama, Tetsuya Ichimiya, Yoshiro Okubo, Akihiro Takano, Tomomichi Ando, Makoto Inoue, Jun Maeda, Kazutoshi Suzuk. Inhibitory effect of hippocampal 5-HT1A receptors on human explicit memory. The American journal of psychiatry. vol 160. issue 2. 2003-03-04. PMID:12562581. |
recent studies have indicated that the serotonergic (5-ht) system plays important roles in memory function. |
2003-03-04 |
2023-08-12 |
human |
| Z Hawi, M Dring, A Kirley, D Foley, L Kent, N Craddock, P Asherson, S Curran, A Gould, S Richards, D Lawson, H Pay, D Turic, K Langley, M Owen, M O'Donovan, A Thapar, M Fitzgerald, M Gil. Serotonergic system and attention deficit hyperactivity disorder (ADHD): a potential susceptibility locus at the 5-HT(1B) receptor gene in 273 nuclear families from a multi-centre sample. Molecular psychiatry. vol 7. issue 7. 2003-02-25. PMID:12192616. |
serotonergic system and attention deficit hyperactivity disorder (adhd): a potential susceptibility locus at the 5-ht(1b) receptor gene in 273 nuclear families from a multi-centre sample. |
2003-02-25 |
2023-08-12 |
Not clear |
| N H Bhanji, H C Margolese, M Saint-Laurent, G Chouinar. Dysphoric mania induced by high-dose mirtazapine: a case for 'norepinephrine syndrome'? International clinical psychopharmacology. vol 17. issue 6. 2003-02-25. PMID:12409687. |
histamine h2 receptors are also antagonized, as are postsynaptic serotonin 5-ht2 and 5-ht3 receptors, leading to serotonergic activity primarily via 5-ht1a receptors. |
2003-02-25 |
2023-08-12 |
human |
| Manolis Markianos, John Hatzimanolis, Lefteris Lykoura. Relationship between prolactin responses to ECT and dopaminergic and serotonergic responsivity in depressed patients. European archives of psychiatry and clinical neuroscience. vol 252. issue 4. 2003-02-24. PMID:12242577. |
before the ect course, we assessed the central serotonergic and dopaminergic responsivities, by measuring the prl responses to the administration of the serotonin uptake inhibitor clomipramine (cmi) intravenously, and, two days later, the prl responses dopamine receptor blocker haloperidol (hal), administered intramuscularly. |
2003-02-24 |
2023-08-12 |
human |
| Ikuko Yamada, Tsuneo Iwasak. [Anxiety-like behavior in rats neonatally and adultly treated with 5,7-dihydroxytryptamine]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 22. issue 5. 2003-02-20. PMID:12451684. |
the administration of serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-dht) into adult rats has been shown to produce a prolonged reduction in the content of brain 5-ht along with anxiolytic effects. |
2003-02-20 |
2023-08-12 |
rat |
| J R Beck-Lie A Fat, T K Birkenhäger, J W Rene. [Manic state during the addition of lithium in the case of depression resistant to imipramine]. Nederlands tijdschrift voor geneeskunde. vol 146. issue 45. 2003-02-13. PMID:12474557. |
in animal experiments lithium addition resulted in a rapid increase in serotonergic neurotransmission, due to an increase in serotonin synthesis and release. |
2003-02-13 |
2023-08-12 |
Not clear |
| Nicoletta Sonino, Giovanni A Fav. Erratum to "CNS drugs in Cushing's disease: pathophysiological and therapeutic implications for mood disorders" [Prog. Neuro-Psycol. Biol. Psychiatry, 26, 763 (2002)]. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 5. 2003-02-11. PMID:12369251. |
since central serotonergic regulation could have a role in the course of cushing's disease, serotonin antagonists (e.g., cyproheptadine, ritanserin and ketanserin) have been employed. |
2003-02-11 |
2023-08-12 |
Not clear |
| Nathaniel D Daw, Sham Kakade, Peter Daya. Opponent interactions between serotonin and dopamine. Neural networks : the official journal of the International Neural Network Society. vol 15. issue 4-6. 2003-02-11. PMID:12371515. |
we suggest that a tonic serotonergic signal reports the long-run average reward rate as part of an average-case reinforcement learning model; that a tonic dopaminergic signal reports the long-run average punishment rate in a similar context; and finally speculate that a phasic serotonin signal might report an ongoing prediction error for future punishment. |
2003-02-11 |
2023-08-12 |
Not clear |
| Yolanda Zea-Ponce, Lawrence S Kegeles, Ningning Guo, Leonid Raskin, Venkatesalu Bakthavachalam, Marc Laruell. Pharmacokinetics and brain distribution in non human primate of R(-)[123I]DOI, A 5HT(2A/2C) serotonin agonist. Nuclear medicine and biology. vol 29. issue 5. 2003-02-10. PMID:12088728. |
although r(-)[123i]doi displayed good brain uptake and localized in serotonergic areas of the brain, its target to non target ratio and its insensitivity to ketanserin displacement suggest high nonspecific uptake, therefore non potentially useful as brain imaging radiotracer for visualization of the agonist high-affinity state of 5-ht(2a) receptors and for visualizing 5-ht(2c) receptors by spect. |
2003-02-10 |
2023-08-12 |
human |
| Roberto A Prado-Alcalá, María Isabel Ruiloba, Laura Rubio, Rafael Solana-Figueroa, Cristina Medina, Rigoberto Salado-Castillo, Gina L Quirart. Regional infusions of serotonin into the striatum and memory consolidation. Synapse (New York, N.Y.). vol 47. issue 3. 2003-02-04. PMID:12494399. |
in light of the differential distribution of serotonergic elements within the striatum, a prediction was made that focal injections of serotonin into distinctive regions would produce dissimilar effects on memory. |
2003-02-04 |
2023-08-12 |
rat |
| F Béquet, D Gomez-Merino, M Berthelot, C Y Guezenne. Evidence that brain glucose availability influences exercise-enhanced extracellular 5-HT level in hippocampus: a microdialysis study in exercising rats. Acta physiologica Scandinavica. vol 176. issue 1. 2003-01-31. PMID:12193220. |
the relationship between brain glucose and serotonin is still unclear and no direct evidence of an action of brain glucose on serotonergic metabolism in central fatigue phenomena has been shown yet. |
2003-01-31 |
2023-08-12 |
rat |
| F Béquet, D Gomez-Merino, M Berthelot, C Y Guezenne. Evidence that brain glucose availability influences exercise-enhanced extracellular 5-HT level in hippocampus: a microdialysis study in exercising rats. Acta physiologica Scandinavica. vol 176. issue 1. 2003-01-31. PMID:12193220. |
in order to determine whether or not brain glucose could influence the brain 5-hydroxytryptamine (5-ht) system, we have monitored in microdialysis the effects of a direct injection of glucose in rat brain hippocampus on serotonergic metabolism [i.e. |
2003-01-31 |
2023-08-12 |
rat |
| F Béquet, D Gomez-Merino, M Berthelot, C Y Guezenne. Evidence that brain glucose availability influences exercise-enhanced extracellular 5-HT level in hippocampus: a microdialysis study in exercising rats. Acta physiologica Scandinavica. vol 176. issue 1. 2003-01-31. PMID:12193220. |
in conclusion, this study demonstrates that brain glucose can act on serotonergic metabolism and thus can prevent exercise-induced increase of 5-ht levels. |
2003-01-31 |
2023-08-12 |
rat |
| Edward G Behrens, Brett R Schofield, Ann M Thompso. Aminergic projections to cochlear nucleus via descending auditory pathways. Brain research. vol 955. issue 1-2. 2003-01-31. PMID:12419519. |
the brainstems were silver-enhanced to visualize the tracer and then immunohistochemically processed with antibodies raised against serotonin or dopamine-beta-hydroxylase (dbh) to label serotonergic or noradrenergic fibers, respectively. |
2003-01-31 |
2023-08-12 |
Not clear |
| Lukasz Struzik, James Duffin, Monica Vermani, Kathleen Hegadoren, Martin A Katzma. Effects of tryptophan depletion on central and peripheral chemoreflexes in man. Respiratory physiology & neurobiology. vol 133. issue 3. 2003-01-29. PMID:12425967. |
serotonergic deficiencies enhance this ventilatory response in pd patients, as per 'suffocation alarm' theory predictions, suggesting that serotonin (5-ht) normalizes the ventilatory response. |
2003-01-29 |
2023-08-12 |
Not clear |