| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Donald H Edwards, Shih-Rung Yeh, Barbara E Musolf, Brian L Antonsen, Franklin B Krasn. Metamodulation of the crayfish escape circuit. Brain, behavior and evolution. vol 60. issue 6. 2003-05-22. PMID:12563168. |
first, the serotonergic modulation of the lateral giant (lg) command neuron for escape depends on the pattern of exposure of the cell to serotonin. |
2003-05-22 |
2023-08-12 |
human |
| Jens Malmkvist, Steffen W Hansen, Birthe M Damgaar. Effect of the serotonin agonist buspirone on behaviour and hypothalamic-pituitary-adrenal axis in confident and fearful mink. Physiology & behavior. vol 78. issue 2. 2003-05-20. PMID:12576120. |
the central serotonergic system may be involved, and even though the precise underlying mechanisms are presently unknown, treatment with a 5-ht(1a) receptor agonist reduces the difference between confident and fearful mink in hpa axis reactivity. |
2003-05-20 |
2023-08-12 |
Not clear |
| I Miklya, B Knoll, J Knol. An HPLC tracing of the enhancer regulation in selected discrete brain areas of food-deprived rats. Life sciences. vol 72. issue 25. 2003-05-19. PMID:12697275. |
to test the validity of the working hypothesis that in any form of goal-seeking behavior the catecholaminergic and serotonergic neurons work on a higher activity level, we compared the amount of norepinephrine, dopamine, and serotonin released from selected discrete brain areas isolated from the brain of sated and food-deprived rats. |
2003-05-19 |
2023-08-12 |
rat |
| Motoko Honda, Takashi Nishida, Hideki On. Tricyclic analogs cyclobenzaprine, amitriptyline and cyproheptadine inhibit the spinal reflex transmission through 5-HT(2) receptors. European journal of pharmacology. vol 458. issue 1-2. 2003-05-16. PMID:12498911. |
these results suggest that the inhibitory effects of cyclobenzaprine, amitriptyline, and cyproheptadine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-ht(2) receptors in the spinal cord. |
2003-05-16 |
2023-08-12 |
rat |
| Dariusz Matosiuk, Sylwia Fidecka, Lucyna Antkiewicz-Michaluk, Izabela Dybala, Anna E Kozio. Synthesis and pharmacological activity of new carbonyl derivatives of 1-aryl-2-iminoimidazolidine. Part 3. Synthesis and pharmacological activity of 1-aryl-5,6(1H)dioxo-2,3-dihydroimidazo[1,2-a]imidazoles. European journal of medicinal chemistry. vol 37. issue 10. 2003-05-15. PMID:12446043. |
the probable receptor inhibition mechanism of their analgesic and serotonergic activity was confirmed in the binding assay tests (by radioligand displacement) toward the opioid mu and serotonin 5-ht(2) receptors. |
2003-05-15 |
2023-08-12 |
mouse |
| Ashwin A Patkar, Raman Gopalakrishnan, Wade H Berrettini, Stephen P Weinstein, Michael J Vergare, Frank T Leon. Differences in platelet serotonin transporter sites between African-American tobacco smokers and non-smokers. Psychopharmacology. vol 166. issue 3. 2003-05-07. PMID:12589524. |
the serotonin transporter (5htt) regulates the magnitude and duration of serotonergic neurotransmission. |
2003-05-07 |
2023-08-12 |
Not clear |
| A Bortolozzi, F Artiga. Control of 5-hydroxytryptamine release in the dorsal raphe nucleus by the noradrenergic system in rat brain. Role of alpha-adrenoceptors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 3. 2003-05-07. PMID:12629522. |
the interactions between the brainstem serotonergic (5-hydroxytryptamine, 5-ht) and noradrenergic (na) systems are important for the pathophysiology and treatment of affective disorders. |
2003-05-07 |
2023-08-12 |
rat |
| Luz Romero, Pau Celada, Raúl Martín-Ruiz, Llorenç Díaz-Mataix, Marisabel Mourelle, Joaquim Delgadillo, Ildefonso Hervás, Francesc Artiga. Modulation of serotonergic function in rat brain by VN2222, a serotonin reuptake inhibitor and 5-HT1A receptor agonist. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 3. 2003-05-07. PMID:12629524. |
modulation of serotonergic function in rat brain by vn2222, a serotonin reuptake inhibitor and 5-ht1a receptor agonist. |
2003-05-07 |
2023-08-12 |
rat |
| Jürgen Gallinat, Daniel Senkowski, Catrin Wernicke, Georg Juckel, Isabell Becker, Thomas Sander, Michael Smolka, Ulrich Hegerl, Hans Rommelspacher, Georg Winterer, Werner M Herrman. Allelic variants of the functional promoter polymorphism of the human serotonin transporter gene is associated with auditory cortical stimulus processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 3. 2003-05-07. PMID:12629533. |
allelic variants in the promoter region of the 5-hydroxytryptamine transporter (5-htt) gene were shown to modulate serotonergic activity. |
2003-05-07 |
2023-08-12 |
human |
| Jürgen Gallinat, Daniel Senkowski, Catrin Wernicke, Georg Juckel, Isabell Becker, Thomas Sander, Michael Smolka, Ulrich Hegerl, Hans Rommelspacher, Georg Winterer, Werner M Herrman. Allelic variants of the functional promoter polymorphism of the human serotonin transporter gene is associated with auditory cortical stimulus processing. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 3. 2003-05-07. PMID:12629533. |
the results are consistent with the reported association between 5-htt genotype and serotonin transport capacity in lymphoblasts, and indicate that auditory stimulus processing is associated with genetic variants of the brain serotonergic system. |
2003-05-07 |
2023-08-12 |
human |
| Seiichiro Shimazu, Akie Tanigawa, Noriyuki Sato, Fumio Yoneda, Kyozo Hayashi, Joseph Knol. Enhancer substances: selegiline and R-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-BPAP] enhance the neurotrophic factor synthesis on cultured mouse astrocytes. Life sciences. vol 72. issue 24. 2003-05-07. PMID:12679194. |
r-(-)-1-(benzofuran-2-yl)-2-propylaminopentane [(-)-bpap] is a potent "catecholaminergic and serotonergic activity enhancer (cae/sae)", which enhances the impulse-evoked catecholamines and serotonin release, e.g. |
2003-05-07 |
2023-08-12 |
mouse |
| K Iwamoto, T Kat. Effects of cocaine and reserpine administration on RNA editing of rat 5-HT2C receptor estimated by primer extension combined with denaturing high-performance liquid chromatography. The pharmacogenomics journal. vol 2. issue 5. 2003-05-06. PMID:12439740. |
to test whether the rna editing of 5-ht(2c)r is regulated by serotonergic activity, effects of cocaine or reserpine administration in the rat cerebral cortex were examined. |
2003-05-06 |
2023-08-12 |
rat |
| J J Lee, M J Crouche. Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission. Neuroscience. vol 117. issue 3. 2003-05-05. PMID:12617971. |
actions of group i and group ii metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission. |
2003-05-05 |
2023-08-12 |
human |
| J J Lee, M J Crouche. Actions of Group I and Group II metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission. Neuroscience. vol 117. issue 3. 2003-05-05. PMID:12617971. |
the failure of (s)-mcpg alone to modify cortical 5-ht release suggests that group ii mglu receptors do not tonically modulate serotonergic neurotransmission in the cerebral cortex but this does not preclude an important functional role for these receptors during pathological conditions when endogenous neurotransmitter levels become excessively elevated. |
2003-05-05 |
2023-08-12 |
human |
| Ying Liu, Yoshiyuki Ishida, Koh Shinoda, Shoji Nakamur. Effects of repeated stress on regeneration of serotonergic and noradrenergic axons in the cerebral cortex of adult rats. Neuroscience letters. vol 339. issue 3. 2003-05-05. PMID:12633894. |
we examined whether regeneration of serotonergic (5-ht) and noradrenergic (na) axons might be affected by stress. |
2003-05-05 |
2023-08-12 |
rat |
| Baojian Yu, Jie Liu, David H Overstreet, Joel P Gallaghe. Serotonin produces an enhanced outward current recorded at rat dorsal lateral septal neurons from the Flinders Sensitive Line of rats, a genetically-selected animal model of depression. Neuroscience letters. vol 339. issue 3. 2003-05-05. PMID:12633896. |
abnormalities in serotonin (5-ht), serotonin receptors, and serotonergic neurons have been reported in studies of brains from patients diagnosed clinically with depression. |
2003-05-05 |
2023-08-12 |
rat |
| Takashi Yoshitake, Ilkka Reenilä, Sven Ove Ogren, Tomas Hökfelt, Jan Keh. Galanin attenuates basal and antidepressant drug-induced increase of extracellular serotonin and noradrenaline levels in the rat hippocampus. Neuroscience letters. vol 339. issue 3. 2003-05-05. PMID:12633897. |
it is concluded that intraventricularly administered galanin attenuated both basal 5-ht and na release and antidepressant drug-induced accumulation of extracellular 5-ht and na levels most likely via a predominant inhibitory action on serotonergic and noradrenergic neurons in the raphe and locus coeruleus, respectively. |
2003-05-05 |
2023-08-12 |
rat |
| Sandra Orozco-Suárez, Alma Rosa Del Angel, Carlos Beas-Zárate, Gabriel Manjarrrez, Alfredo Feria-Velasc. Corn feeding during development induces changes in the number of serotonergic neurons in the raphe nuclei. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 21. issue 1. 2003-04-30. PMID:12565692. |
5-ht immunohistochemistry was revealed by avidin-biotin complex (abc) method to quantify serotonergic nerve cells in the nine raphe nuclei. |
2003-04-30 |
2023-08-12 |
rat |
| B C Hains, K M Johnson, M J Eaton, W D Willis, C E Hulsebosc. Serotonergic neural precursor cell grafts attenuate bilateral hyperexcitability of dorsal horn neurons after spinal hemisection in rat. Neuroscience. vol 116. issue 4. 2003-04-30. PMID:12617951. |
presuming that this hyperexcitability can be explained in part by interruption of descending inhibitory modulation by serotonin, we hypothesized that intrathecal transplantation of rn46a-b14 serotonergic precursor cells, which secrete serotonin and brain-derived neurotrophic factor, would reduce this hyperexcitability by normalizing the responses of low-threshold mechanoreceptive, nociceptive-specific, and multireceptive dorsal horn neurons. |
2003-04-30 |
2023-08-12 |
rat |
| Gabriela Rodríguez-Manzo, Carolina López-Rubalcava, Rene Hen, Alonso Fernández-Guast. Participation of 5-HT(1B) receptors in the inhibitory actions of serotonin on masculine sexual behaviour of mice: pharmacological analysis in 5-HT(1B) receptor knockout mice. British journal of pharmacology. vol 136. issue 8. 2003-04-28. PMID:12163345. |
in addition, the diminished sensitivity to serotonergic stimulation exhibited by ko(1b) mice suggests the occurrence of compensatory changes as a consequence of the absence of the 5-ht(1b) receptor subtype. |
2003-04-28 |
2023-08-12 |
mouse |