| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Czyrak, Marzena Maćkowiak, Agnieszka Chocyk, Katarzyna Fijał, Anna Gadek-Michalska, Krzysztof Wedzon. 8-OHDPAT-induced disruption of prepulse inhibition in rats is attenuated by prolonged corticosterone treatment. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 7. 2003-09-02. PMID:12700680. |
chronic corticosterone treatment modulated also the neuronal activity of serotonergic pathways in the brain decreasing the level of 5-hiaa in the raphe nuclei and increasing both 5-ht and 5-hiaa levels in the hippocampus. |
2003-09-02 |
2023-08-12 |
rat |
| John F Bowyer, John F Young, William Slikker, Yossef Itzak, A J Mayorga, Glenn D Newport, Syed F Ali, David L Frederick, Merle G Paul. Plasma levels of parent compound and metabolites after doses of either d-fenfluramine or d-3,4-methylenedioxymethamphetamine (MDMA) that produce long-term serotonergic alterations. Neurotoxicology. vol 24. issue 3. 2003-09-02. PMID:12782103. |
there were 80% reductions in the plasma membrane-associated 5-ht transporters 6 months after either the fen or mdma dosing regimen indicating that both treatments produced long-term serotonergic effects. |
2003-09-02 |
2023-08-12 |
human |
| Lora K Heisler, Michael A Cowley, Toshiro Kishi, Laurence H Tecott, Wei Fan, Malcolm J Low, James L Smart, Marcelo Rubinstein, Jeffrey B Tatro, Jeffrey M Zigman, Roger D Cone, Joel K Elmquis. Central serotonin and melanocortin pathways regulating energy homeostasis. Annals of the New York Academy of Sciences. vol 994. 2003-08-29. PMID:12851313. |
recently, we investigated the mechanisms through which central serotonergic (5-hydroxytryptamine, 5-ht) systems recruit leptin-responsive hypothalamic pathways, such as the melanocortin systems, to affect energy balance. |
2003-08-29 |
2023-08-12 |
Not clear |
| Jon C Cole, Harry R Sumnal. The pre-clinical behavioural pharmacology of 3,4-methylenedioxymethamphetamine (MDMA). Neuroscience and biobehavioral reviews. vol 27. issue 3. 2003-08-20. PMID:12788333. |
mdma is known as a selective serotonergic neurotoxin in a variety of animal species but acutely it is a potent releaser and/or reuptake inhibitor of presynaptic serotonin, dopamine, noradrenaline, and acetylcholine. |
2003-08-20 |
2023-08-12 |
Not clear |
| Rivka Ofir, Snait Tamir, Soliman Khatib, Jacob Vay. Inhibition of serotonin re-uptake by licorice constituents. Journal of molecular neuroscience : MN. vol 20. issue 2. 2003-08-18. PMID:12794307. |
in conclusion, this study showed that several isoflavans are unique phytoestrogens, which like estradiol, affects the serotonergic system and inhibits serotonin re-uptake and, thus, potentially may be beneficial for mild to moderate depression in pre- and postmenopausal women. |
2003-08-18 |
2023-08-12 |
human |
| Alexis Hattox, Ying Li, Asaf Kelle. Serotonin regulates rhythmic whisking. Neuron. vol 39. issue 2. 2003-08-18. PMID:12873389. |
these findings suggest that serotonin is both necessary and sufficient to generate rhythmic whisker movements and that serotonergic premotoneurons are part of a whisking cpg. |
2003-08-18 |
2023-08-12 |
Not clear |
| A Birthelmer, J Stemmelin, R Jackisch, J-C Casse. Presynaptic modulation of acetylcholine, noradrenaline, and serotonin release in the hippocampus of aged rats with various levels of memory impairments. Brain research bulletin. vol 60. issue 3. 2003-08-08. PMID:12754090. |
data show that aging alters cholinergic and serotonergic hippocampal innervations, release of ach and 5-ht, but not presynaptic release-modulating mechanisms. |
2003-08-08 |
2023-08-12 |
rat |
| Denise M Inman, Oswald Stewar. Ascending sensory, but not other long-tract axons, regenerate into the connective tissue matrix that forms at the site of a spinal cord injury in mice. The Journal of comparative neurology. vol 462. issue 4. 2003-08-08. PMID:12811811. |
spinal cords from other mice were prepared for immunocytochemistry using antibodies against neurofilament protein (nf), 5-ht to reveal descending serotonergic axons, calcitonin gene-related protein (cgrp) to reveal ascending sensory axons, and chondroitin sulfate proteoglycan (cspg) to assess the distribution of molecules that are inhibitory to axon growth. |
2003-08-08 |
2023-08-12 |
mouse |
| Giuseppe Romeo, Luisa Materia, Fabrizio Manetti, Alfredo Cagnotto, Tiziana Mennini, Ferdinando Nicoletti, Maurizio Botta, Filippo Russo, Kenneth P Minnema. New pyrimido[5,4-b]indoles as ligands for alpha(1)-adrenoceptor subtypes. Journal of medicinal chemistry. vol 46. issue 14. 2003-08-07. PMID:12825930. |
some compounds, including 39 and 40, displayed substantial alpha(1d)-ar selectivity with respect to alpha(1a)-ar, alpha(1b)-ar, serotonergic 5-ht(1a), 5-ht(1b), 5-ht(2a), and dopaminergic d(1) and d(2) receptors. |
2003-08-07 |
2023-08-12 |
human |
| André Rex, Heike Thomas, Heide Hörtnagl, Mechthild Voits, Heidrun Fin. Behavioural and microdialysis study after neurotoxic lesion of the dorsal raphe nucleus in rats. Pharmacology, biochemistry, and behavior. vol 74. issue 3. 2003-08-04. PMID:12543223. |
destruction of the serotonergic neurons in the drn changed neither anxiety-related behaviour on the elevated plus maze, nor aversion-induced 5-ht release in the brain. |
2003-08-04 |
2023-08-12 |
rat |
| Thomas Nickel, Annette Sonntag, Julia Schill, Astrid W Zobel, Nibal Ackl, Alexander Brunnauer, Harald Murck, Marcus Ising, Alexander Yassouridis, Axel Steiger, Josef Zihl, Florian Holsboe. Clinical and neurobiological effects of tianeptine and paroxetine in major depression. Journal of clinical psychopharmacology. vol 23. issue 2. 2003-08-01. PMID:12640217. |
in contrast to the ssris, which block the presynaptic serotonin (5-ht) transporter and by this route increase the concentration of serotonin in the synaptic cleft, the antidepressant tianeptine enhances the presynaptic neuronal reuptake of 5-ht and thus decreases serotonergic neurotransmission. |
2003-08-01 |
2023-08-12 |
Not clear |
| Scott V Adams, Louis J DeFelic. Flux coupling in the human serotonin transporter. Biophysical journal. vol 83. issue 6. 2003-07-31. PMID:12496095. |
in the brain, sert clears 5ht from extracellular spaces, modulating the strength and duration of serotonergic signaling. |
2003-07-31 |
2023-08-12 |
human |
| R L Ganno. Serotonergic serotonin (1A) mixed agonists/antagonists elicit large-magnitude phase shifts in hamster circadian wheel-running rhythms. Neuroscience. vol 119. issue 2. 2003-07-30. PMID:12770569. |
serotonergic serotonin (1a) mixed agonists/antagonists elicit large-magnitude phase shifts in hamster circadian wheel-running rhythms. |
2003-07-30 |
2023-08-12 |
Not clear |
| R L Ganno. Serotonergic serotonin (1A) mixed agonists/antagonists elicit large-magnitude phase shifts in hamster circadian wheel-running rhythms. Neuroscience. vol 119. issue 2. 2003-07-30. PMID:12770569. |
the retinal input to the clock is inhibited by exogenously applied serotonin agonists, perhaps mimicking an endogenous inhibitory serotonergic input to the clock arriving from the midbrain raphe. |
2003-07-30 |
2023-08-12 |
Not clear |
| R L Ganno. Serotonergic serotonin (1A) mixed agonists/antagonists elicit large-magnitude phase shifts in hamster circadian wheel-running rhythms. Neuroscience. vol 119. issue 2. 2003-07-30. PMID:12770569. |
the serotonergic ligands 8-(2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl)-8-azaspiro(4.5)decane-7,9-dione dihydrochloride (bmy 7378), s 15535, and 8-[2-(1,4-benzodioxan-2-ylmethylamino)ethyl]-8-azaspiro[4.5]decane-7,9-dione hydrochloride (mdl 73005 ef) can all be classified as mixed agonists/antagonists at type 1a serotonin receptors. |
2003-07-30 |
2023-08-12 |
Not clear |
| A M S Kindlundh, J Lindblom, L Bergström, F Nyber. The anabolic-androgenic steroid nandrolone induces alterations in the density of serotonergic 5HT1B and 5HT2 receptors in the male rat brain. Neuroscience. vol 119. issue 1. 2003-07-28. PMID:12763073. |
since such behavioral states have been related to an imbalanced serotonergic system and the involvement of the serotonergic 5ht(1b) and the 5ht(2) receptors, it was important to discern the impact of aas on these receptors. |
2003-07-28 |
2023-08-12 |
rat |
| A M S Kindlundh, J Lindblom, L Bergström, F Nyber. The anabolic-androgenic steroid nandrolone induces alterations in the density of serotonergic 5HT1B and 5HT2 receptors in the male rat brain. Neuroscience. vol 119. issue 1. 2003-07-28. PMID:12763073. |
in conclusion, serotonergic 5ht(1b) or 5ht(2) receptors are likely to play important roles in mediating observed emotional states and behavioral changes among aas abusers. |
2003-07-28 |
2023-08-12 |
rat |
| E T Larson, D O Norris, C H Summer. Monoaminergic changes associated with socially induced sex reversal in the saddleback wrasse. Neuroscience. vol 119. issue 1. 2003-07-28. PMID:12763086. |
this study suggests that monoamines play a very important role in both behavioral and gonadal sex reversal in the saddleback wrasse, the former under the control of serotonin in the raphe and the latter mediated via serotonergic effects on norepinephrine in the preoptic area. |
2003-07-28 |
2023-08-12 |
Not clear |
| Ashwin A Patkar, Wade H Berrettini, Allan Lundy, Heather W Murray, Kevin P Hill, Michael J Vergare, Stephen P Weinstei. Seasonal variations in the binding of [3H]paroxetine to the platelet serotonin transporter sites in African-American cocaine-dependent patients and healthy volunteers. Human psychopharmacology. vol 18. issue 2. 2003-07-22. PMID:12590403. |
although seasonal fluctuations in several indices of serotonin function have been described, little is known about seasonality and serotonergic activity in substance abusers. |
2003-07-22 |
2023-08-12 |
human |
| Eitan Gur, Michael E Newman, Yosefa Avraham, Eliyahu Dremencov, Elliot M Berr. The differential effects of food restriction on 5-HT1A and 5-HT1B receptor mediated control of serotonergic transmission in the hippocampus and hypothalamus of rats. Nutritional neuroscience. vol 6. issue 3. 2003-07-18. PMID:12793521. |
since 5-ht1b receptors regulate 5-ht release by a negative feedback mechanism, the decrease in sensitivity of 5-ht1b receptors in the hypothalamus of fr rats indicates increased serotonergic transmission in these rats. |
2003-07-18 |
2023-08-12 |
rat |