| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sylvia Montañez, Lynette C Daws, Georgianna G Gould, Alan Fraze. Serotonin (5-HT) transporter (SERT) function after graded destruction of serotonergic neurons. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622117. |
functional loss of sert activity occurs when destruction of serotonergic innervation is greater than 90% but serotonin clearance and efficacy of fluvoxamine is maintained with as few as one fifth of a full complement of serts. |
2004-01-14 |
2023-08-12 |
rat |
| A S Ivy, F G Rodriguez, C Garcia, M J Chen, A A Russo-Neustad. Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant. Pharmacology, biochemistry, and behavior. vol 75. issue 1. 2004-01-07. PMID:12759116. |
much evidence regarding the initial actions of antidepressant medications as well as exercise leads to the hypothesis that noradrenergic (ne) and/or serotonergic (5-ht) activation is a key element in the bdnf transcriptional elevation common to both interventions. |
2004-01-07 |
2023-08-12 |
Not clear |
| Christian P Müller, Robert J Carey, Joseph P Husto. Serotonin as an important mediator of cocaine's behavioral effects. Drugs of today (Barcelona, Spain : 1998). vol 39. issue 7. 2004-01-06. PMID:12973400. |
although the dopaminergic system still plays an important role in the investigation of the behavioral effects of cocaine, a broad literature emerged parallel to this research that provided significant evidence for an important contribution of the serotonergic (5-hydroxytryptamine, 5-ht) system. |
2004-01-06 |
2023-08-12 |
Not clear |
| Kristine Krajnak, Katherine L Rosewell, Marilyn J Duncan, Phyllis M Wis. Aging, estradiol and time of day differentially affect serotonin transporter binding in the central nervous system of female rats. Brain research. vol 990. issue 1-2. 2004-01-06. PMID:14568333. |
estrogen-related changes in serotonergic neuronal transmission, including changes in the number of serotonin transporter (sert) binding sites, have been cited as a possible cause for changes in mood, memory and sleep that occur during the menopausal transition. |
2004-01-06 |
2023-08-12 |
rat |
| Mark Berner Hanse. The enteric nervous system III: a target for pharmacological treatment. Pharmacology & toxicology. vol 93. issue 1. 2004-01-05. PMID:12828568. |
the diagnosis of gastrointestinal neuropathy, the role of serotonin and related neuroendocrine transmitters, serotonergic drugs, and neurotrophic factors in neurogastrointestinal pharmacology will be addressed in this context. |
2004-01-05 |
2023-08-12 |
Not clear |
| Pierre Oswald, Daniel Souery, Julien Mendlewic. Molecular genetics of affective disorders. The international journal of neuropsychopharmacology. vol 6. issue 2. 2004-01-05. PMID:12890309. |
tryptophan hydroxylase and serotonin transporter genes, related to the serotonergic pathway, have been found to be associated to suicidal behaviour, in particular violent suicidal behaviour but need to be replicated before definitive conclusion. |
2004-01-05 |
2023-08-12 |
Not clear |
| Patricia Gaspar, Olivier Cases, Luc Maroteau. The developmental role of serotonin: news from mouse molecular genetics. Nature reviews. Neuroscience. vol 4. issue 12. 2004-01-05. PMID:14618156. |
in addition, studies have revealed that serotonergic traits are dissociable, as there are populations of neurons that contain serotonin but do not synthesize it. |
2004-01-05 |
2023-08-12 |
mouse |
| Carolyn W Harle. Norepinephrine and serotonin axonal dynamics and clinical depression: a commentary on the interaction between serotonergic and noradrenergic axons during axonal regeneration. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637074. |
norepinephrine and serotonin axonal dynamics and clinical depression: a commentary on the interaction between serotonergic and noradrenergic axons during axonal regeneration. |
2004-01-05 |
2023-08-12 |
Not clear |
| Ying Liu, Yoshiyuki Ishida, Koh Shinoda, Shoji Nakamur. Interaction between serotonergic and noradrenergic axons during axonal regeneration. Experimental neurology. vol 184. issue 1. 2004-01-05. PMID:14637090. |
the present experiments focused on the morphological interaction between serotonergic (5-ht) and noradrenergic (na) axons during regeneration following partial axonal denervation in the cerebral cortex in adult rats. |
2004-01-05 |
2023-08-12 |
rat |
| Alena Lira, Mingming Zhou, Nathalie Castanon, Mark S Ansorge, Joshua A Gordon, Jasmine H Francis, Maria Bradley-Moore, Josko Lira, Mark D Underwood, Victoria Arango, Hank F Kung, Myron A Hofer, René Hen, Jay A Gingric. Altered depression-related behaviors and functional changes in the dorsal raphe nucleus of serotonin transporter-deficient mice. Biological psychiatry. vol 54. issue 10. 2003-12-29. PMID:14625138. |
as a key regulator of serotonergic activity and target of many antidepressant treatments, the serotonin transporter (sert) represents a potential mediator of anxiety- and depression-related behaviors. |
2003-12-29 |
2023-08-12 |
mouse |
| Jannette Rodriguez-Pallares, Maria J Guerra, Jose L Labandeira-Garci. Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors. The European journal of neuroscience. vol 18. issue 8. 2003-12-23. PMID:14622177. |
cell aggregates treated with an antibody against fgf-4 or with the serotonergic toxin 5,7-dyhydroxytryptamine or the serotonin synthesis inhibitor dl-p-chlorophenylalanine showed a marked decrease in the number of 5-ht-ir cells (10-20% of controls) and a marked increase in that of th-ir neurons (700-900% of controls). |
2003-12-23 |
2023-08-12 |
rat |
| Andrea Rapki. A review of treatment of premenstrual syndrome and premenstrual dysphoric disorder. Psychoneuroendocrinology. vol 28 Suppl 3. 2003-12-19. PMID:12892989. |
pharmacologic management with at least ten randomized controlled trials to support efficacy include selective serotonin reuptake inhibitors administered daily or premenstrually and serotonergic tricyclic antidepressants. |
2003-12-19 |
2023-08-12 |
Not clear |
| Thomas C Baghai, Cornelius Schule, Peter Zwanzger, Peter Zill, Robin Ella, Daniela Eser, Tobias Deiml, Christo Minov, Rainer Rupprecht, Brigitta Bond. No Influence of a functional polymorphism within the serotonin transporter gene on partial sleep deprivation in major depression. The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry. vol 4. issue 3. 2003-12-09. PMID:12872203. |
because genetic variations influencing neurotransmission could have an impact on therapeutic outcome and stability of improvement, we investigated the functional polymorphism of the serotonin transporter (5-htt) gene, the 5-htt-linked polymorphic region (5-httlpr), to examine the serotonergic pathway. |
2003-12-09 |
2023-08-12 |
Not clear |
| P Ohliger-Frerking, B A Horwitz, J M Horowit. Serotonergic dorsal raphe neurons from obese zucker rats are hyperexcitable. Neuroscience. vol 120. issue 3. 2003-12-04. PMID:12895503. |
these results suggest a potential mechanism for the reported increase in 5-ht release at the vmh of obese rats during feeding, and provide the first direct evidence of changes in the intrinsic activity of serotonergic neurons, which are crucial regulators of feeding behavior, in a genetic model of obesity. |
2003-12-04 |
2023-08-12 |
rat |
| Randy A Sansone, Lori A Sanson. Sertraline-induced hyperglycemia: case report. International journal of psychiatry in medicine. vol 33. issue 1. 2003-12-04. PMID:12906348. |
empirical studies with humans suggest that selective serotonin reuptake inhibitors (ssris) may, through increases in serotonergic activity, increase insulin secretion, increase insulin sensitivity, and lower serum glucose levels. |
2003-12-04 |
2023-08-12 |
Not clear |
| Yaffa Vered, Pavel Golubchik, Tamar Mozes, Rael Strous, Allon Nechmad, Roberto Mester, Abraham Weizman, Baruch Spiva. The platelet-poor plasma 5-HT response to carbohydrate rich meal administration in adult autistic patients compared with normal controls. Human psychopharmacology. vol 18. issue 5. 2003-12-02. PMID:12858328. |
the carbohydrate-rich meal test (crmt) is a dietary manipulation that could significantly influence platelet-poor plasma (ppp) 5-ht levels and reflect the responsiveness of the serotonergic system in 'free' plasma. |
2003-12-02 |
2023-08-12 |
Not clear |
| Leping Cheng, Chih-Li Chen, Ping Luo, Min Tan, Mengsheng Qiu, Randy Johnson, Qiufu M. Lmx1b, Pet-1, and Nkx2.2 coordinately specify serotonergic neurotransmitter phenotype. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 23. issue 31. 2003-12-02. PMID:14602809. |
serotonergic (5-ht) neurons in the brainstem modulate a wide range of physiological processes and behaviors. |
2003-12-02 |
2023-08-12 |
mouse |
| Ashwin A Patkar, Raman Gopalakrishnan, Prakash C Naik, Heather W Murray, Michael J Vergare, Charles A Marsde. Changes in plasma noradrenaline and serotonin levels and craving during alcohol withdrawal. Alcohol and alcoholism (Oxford, Oxfordshire). vol 38. issue 3. 2003-11-18. PMID:12711656. |
despite substantial preclinical evidence that supports the involvement of noradrenergic (na) and serotonergic (5-ht) mechanisms in alcohol withdrawal, human data remain inconsistent. |
2003-11-18 |
2023-08-12 |
human |
| B Wirleitner, G Neurauter, K Schröcksnadel, B Frick, D Fuch. Interferon-gamma-induced conversion of tryptophan: immunologic and neuropsychiatric aspects. Current medicinal chemistry. vol 10. issue 16. 2003-11-18. PMID:12871129. |
especially in states of persistent immune activation availability of free serum tryptophan is diminished and as a consequence of reduced serotonin production, serotonergic functions may as well be affected. |
2003-11-18 |
2023-08-12 |
Not clear |
| Connie Sánche. Stress-induced vocalisation in adult animals. A valid model of anxiety? European journal of pharmacology. vol 463. issue 1-3. 2003-11-12. PMID:12600706. |
selective serotonin reuptake inhibitors and other antidepressants that preferentially enhance serotonergic neurotransmission inhibit footshock-induced ultrasonic vocalisation. |
2003-11-12 |
2023-08-12 |
rat |