| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Stephen B Manuck, Jay R Kaplan, Beth A Rymeski, Lynn A Fairbanks, Mark E Wilso. Approach to a social stranger is associated with low central nervous system serotonergic responsivity in female cynomolgus monkeys (Macaca fascicularis). American journal of primatology. vol 61. issue 4. 2004-02-10. PMID:14669270. |
in each animal, the rise in plasma prolactin concentration induced by acute administration of the 5-ht agonist, fenfluramine, was used to assess "net" central serotonergic responsivity. |
2004-02-10 |
2023-08-12 |
human |
| Jordi Serrats, Andreu Raurich, M Teresa Vilaró, Guadalupe Mengod, Roser Corté. 5-ht5B receptor mRNA in the raphe nuclei: coexpression with serotonin transporter. Synapse (New York, N.Y.). vol 51. issue 2. 2004-02-09. PMID:14618677. |
our results support the presence of 5-ht(5b) receptor in serotonergic neurons in the dr and cs, suggesting an autoreceptor role for this receptor subtype. |
2004-02-09 |
2023-08-12 |
rat |
| Hai Miao, Stanislav S Rubakhin, Jonathan V Sweedle. Analysis of serotonin release from single neuron soma using capillary electrophoresis and laser-induced fluorescence with a pulsed deep-UV NeCu laser. Analytical and bioanalytical chemistry. vol 377. issue 6. 2004-02-06. PMID:14551658. |
single cell analysis of serotonergic metacerebral cells from the sea slug aplysia californica yields a value of 800+/-85 fmol of serotonin in each cell soma. |
2004-02-06 |
2023-08-12 |
aplysia |
| Sabri M Khaled, Mostafa Elhilal. Role of 5-HT receptors in treatment of overactive bladder. Drugs of today (Barcelona, Spain : 1998). vol 39. issue 8. 2004-02-06. PMID:14566383. |
experimental studies in animals have revealed that spinal reflex circuits involved in voiding function exhibit a dense serotonergic innervation, multiple 5-ht receptors, and sensitivity to 5-ht receptor agonists and antagonists, and 5-ht reuptake inhibitors. |
2004-02-06 |
2023-08-12 |
Not clear |
| Massimo Bellini, Lucia Rappelli, Corrado Blandizzi, Francesco Costa, Cristina Stasi, Rocchina Colucci, Gino Giannaccini, Donatella Marazziti, Laura Betti, Stefano Baroni, Maria Gloria Mumolo, Santino Marchi, Mario Del Tacc. Platelet serotonin transporter in patients with diarrhea-predominant irritable bowel syndrome both before and after treatment with alosetron. The American journal of gastroenterology. vol 98. issue 12. 2004-02-06. PMID:14687821. |
serotonin reuptake is mediated by a transporter protein (sert), and its dysfunctions can alter serotonergic transmission. |
2004-02-06 |
2023-08-12 |
human |
| Marcel D Waldinger, Aeilko H Zwinderman, Berend Olivie. Antidepressants and ejaculation: a double-blind, randomized, fixed-dose study with mirtazapine and paroxetine. Journal of clinical psychopharmacology. vol 23. issue 5. 2004-01-30. PMID:14520123. |
a double-blind, fixed-dose study in healthy men with lifelong early ejaculation was performed to evaluate potential differences in their effects on ejaculation latency, between clinically relevant doses of the selective serotonin reuptake inhibitor paroxetine and the noradrenergic and specific serotonergic antidepressant mirtazapine. |
2004-01-30 |
2023-08-12 |
Not clear |
| Justin W C Leung, Hong Xu. GABAergic functions and depression: from classical therapies to herbal medicine. Current drug targets. CNS and neurological disorders. vol 2. issue 6. 2004-01-30. PMID:14683464. |
classical medications employed to treat depression comprise mostly tricyclic antidepressants (tcas), specific serotonin reuptake inhibitors (ssris) and monoamine oxidase inhibitors (maois), in accord with the recognized involvement of serotonergic and adrenergic systems in depression. |
2004-01-30 |
2023-08-12 |
Not clear |
| M Doder, E A Rabiner, N Turjanski, A J Lees, D J Brook. Tremor in Parkinson's disease and serotonergic dysfunction: an 11C-WAY 100635 PET study. Neurology. vol 60. issue 4. 2004-01-29. PMID:12601099. |
midbrain raphe 5-ht(1a) binding provides a functional measure of serotonergic system integrity. |
2004-01-29 |
2023-08-12 |
Not clear |
| Miguel Estevez, Annette O Estevez, Robin H Cowie, Kathy L Gardne. The voltage-gated calcium channel UNC-2 is involved in stress-mediated regulation of tryptophan hydroxylase. Journal of neurochemistry. vol 88. issue 1. 2004-01-29. PMID:14675154. |
this same unc-2/tgf-beta pathway is required for accumulation of normal serotonin levels and stress-induced modulation of tryptophan hydroxylase (tph) expression in the serotonergic chemosensory adf neurons, but not the nsm neurons. |
2004-01-29 |
2023-08-12 |
human |
| Clinton Kilt. In vivo neuroimaging correlates of the efficacy of paroxetine in the treatment of mood and anxiety disorders. Psychopharmacology bulletin. vol 37 Suppl 1. 2004-01-28. PMID:14566198. |
the findings of neuroimaging studies of paroxetine will be placed into perspective for a better understanding of the interaction of this selective serotonin reuptake inhibitor (ssri) with the serotonergic and noradrenergic systems in the brain that mediate clinical efficacy. |
2004-01-28 |
2023-08-12 |
Not clear |
| Mark H Pollack, Alicia C Doyl. Treatment of panic disorder: focus on paroxetine. Psychopharmacology bulletin. vol 37 Suppl 1. 2004-01-28. PMID:14566201. |
treatment of panic disorder has evolved significantly in the past 20 years with the availability of serotonergic antidepressants, including the selective serotonin reuptake inhibitors (ssris). |
2004-01-28 |
2023-08-12 |
Not clear |
| Roberto Domínguez, Sara E Cruz-Morales, Milene C Carvalho, Maristela Xavier, Marcus L Branda. Sex differences in serotonergic activity in dorsal and median raphe nucleus. Physiology & behavior. vol 80. issue 2-3. 2004-01-26. PMID:14637217. |
immediately after the test, or 10-12 days later, groups of animals were sacrificed to measure serotonin (5-ht) and 5-hydroxyindolacetic acid (5-hiaa) concentration in the drn and mrn, to calculate the serotonergic activity ([5-hiaa]/[5-ht]). |
2004-01-26 |
2023-08-12 |
rat |
| Stefan Tiefenbacher, Matthew D Davenport, Melinda A Novak, Amber L Pouliot, Jerrold S Meye. Fenfluramine challenge, self-injurious behavior, and aggression in rhesus monkeys. Physiology & behavior. vol 80. issue 2-3. 2004-01-26. PMID:14637232. |
self-injurious behavior (sib) and aggression have been linked to reduced serotonergic (5-ht) functioning in both humans and nonhuman primates. |
2004-01-26 |
2023-08-12 |
human |
| E Paolucci, N Berretta, A Tozzi, G Bernardi, N B Mercur. Depression of mGluR-mediated IPSCs by 5-HT in dopamine neurons of the rat substantia nigra pars compacta. The European journal of neuroscience. vol 18. issue 10. 2004-01-26. PMID:14656323. |
dopamine neurons of the substantia nigra pars compacta receive a prominent serotonin (5-ht) projection from the dorsal raphe nucleus and important functional interactions between the serotonergic and the dopaminergic system have been postulated. |
2004-01-26 |
2023-08-12 |
rat |
| Oliver Pogarell, Christine Hamann, Gabriele Pöpperl, Georg Juckel, Martina Choukèr, Michael Zaudig, Michael Riedel, Hans-Jürgen Möller, Ulrich Hegerl, Klaus Tatsc. Elevated brain serotonin transporter availability in patients with obsessive-compulsive disorder. Biological psychiatry. vol 54. issue 12. 2004-01-26. PMID:14675805. |
the aim of this study was to investigate the serotonin transporter availability in patients with ocd as an in vivo marker of the central serotonergic system. |
2004-01-26 |
2023-08-12 |
Not clear |
| G Bosco, A Rankin, R E Poppel. Modulation of dorsal spinocerebellar responses to limb movement. I. Effect of serotonin. Journal of neurophysiology. vol 90. issue 5. 2004-01-22. PMID:14615434. |
we used two types of perturbation: electrical stimulation of the raphe areas in the brain stem to release serotonin in the spinal cord (42 neurons) and intravenous administration of serotonergic agonists or antagonists, mostly the 5htp2 antagonist ketanserin (30 neurons). |
2004-01-22 |
2023-08-12 |
Not clear |
| Jennifer M Chou-Green, Todd D Holscher, Mary F Dallman, Susan F Akan. Compulsive behavior in the 5-HT2C receptor knockout mouse. Physiology & behavior. vol 78. issue 4-5. 2004-01-16. PMID:12782219. |
the efficacy of serotonergic pharmacotherapy indicates that serotonin (5-ht) plays a role in the treatment, if not the etiology, of obsessive-compulsive disorder (ocd). |
2004-01-16 |
2023-08-12 |
mouse |
| Mercè Amargós-Bosch, Albert Adell, Analía Bortolozzi, Francesc Artiga. Stimulation of alpha1-adrenoceptors in the rat medial prefrontal cortex increases the local in vivo 5-hydroxytryptamine release: reversal by antipsychotic drugs. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622114. |
the stimulation of prefrontal 5-ht2a and ampa receptors increases pyramidal and serotonergic cell firing, and 5-hydroxytryptamine (5-ht) release in mpfc. |
2004-01-14 |
2023-08-12 |
rat |
| Sylvia Montañez, Lynette C Daws, Georgianna G Gould, Alan Fraze. Serotonin (5-HT) transporter (SERT) function after graded destruction of serotonergic neurons. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622117. |
serotonin (5-ht) transporter (sert) function after graded destruction of serotonergic neurons. |
2004-01-14 |
2023-08-12 |
rat |
| Sylvia Montañez, Lynette C Daws, Georgianna G Gould, Alan Fraze. Serotonin (5-HT) transporter (SERT) function after graded destruction of serotonergic neurons. Journal of neurochemistry. vol 87. issue 4. 2004-01-14. PMID:14622117. |
to gain insight into the extent of occupancy required to alter serotonergic neurotransmission we used high-speed chronoamperometry to determine the extent of serotonergic destruction required to reduce the clearance of exogenously administered serotonin from extracellular fluid in the ca3 region of the hippocampus. |
2004-01-14 |
2023-08-12 |
rat |