| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kurt Rasmussen, Andrew C McCreary, Elaine A Shank. Attenuation of the effects of fluoxetine on serotonergic neuronal activity by pindolol in rats. Neuroscience letters. vol 355. issue 1-2. 2004-03-16. PMID:14729220. |
based on its proposed ability to block the effect of selective serotonin reuptake inhibitors (ssris) on the firing rate of serotonergic neurons, the 5-ht1a partial agonist/beta-adrenergic antagonist pindolol has been examined in clinical trials for its ability to enhance the efficacy of ssris. |
2004-03-16 |
2023-08-12 |
rat |
| Zoltán Jank. [Serotonin dysfunctions in the background of the seven deadly sins]. Ideggyogyaszati szemle. vol 56. issue 11-12. 2004-03-16. PMID:14743592. |
results of biochemical and molecular genetic (polymorphism) studies on the human serotonergic system (receptor, transporter, enzyme), findings of functional imaging techniques, effects of depletion (or supplementation) of the serotonin precursor tryptophan, data of challenge probe investigations directed to testing central serotonergic functions, alterations in the peripheral serotonin measures (platelet), and the changes in the csf 5-hydroxy-indoleacetic acid content indicate such serotonergic involvement. |
2004-03-16 |
2023-08-12 |
human |
| Zoltán Jank. [Serotonin dysfunctions in the background of the seven deadly sins]. Ideggyogyaszati szemle. vol 56. issue 11-12. 2004-03-16. PMID:14743592. |
furthermore, results of animal experiments on behaviour change (aggressive, dominant or submissive, appetite, alcohol preference) attributed to serotonin status modification and the clinically evidenced therapeutic efficacy of pharmacological interventions, based on the modulation and perturbation of the serotonergic system (e.g. |
2004-03-16 |
2023-08-12 |
human |
| Shaul Feldman, Joseph Weidenfel. Involvement of endogeneous glutamate in the stimulatory effect of norepinephrine and serotonin on the hypothalamo-pituitary-adrenocortical axis. Neuroendocrinology. vol 79. issue 1. 2004-03-15. PMID:14755133. |
pvn injections of an alpha(1)-adrenergic receptor agonist or a serotonergic 5-ht(1a) receptor agonist markedly increased both adrenocorticotropin (acth) and corticosterone (cs) serum levels. |
2004-03-15 |
2023-08-12 |
rat |
| John H Hughes, Peter Gallagher, Mary E Stewart, David Matthews, Tom P Kelly, Allan H Youn. The effects of acute tryptophan depletion on neuropsychological function. Journal of psychopharmacology (Oxford, England). vol 17. issue 3. 2004-03-12. PMID:14513922. |
by utilizing more specific probes of individual 5-ht receptor subtypes, future studies can fully explore the role of 5-ht in neuropsychological functioning and may elucidate the factors determining vulnerability to the effects of serotonergic dysfunction. |
2004-03-12 |
2023-08-12 |
human |
| Chen-Jee Hong, Guo-Mei Pan, Shih-Jen Tsa. Association study of onset age, attempted suicide, aggressive behavior, and schizophrenia with a serotonin 1B receptor (A-161T) genetic polymorphism. Neuropsychobiology. vol 49. issue 1. 2004-03-08. PMID:14730192. |
located on the presynaptic and postsynaptic terminals of serotonergic neurons, serotonin 1b receptors (5-ht1b) are involved in the modulation of serotonergic activity. |
2004-03-08 |
2023-08-12 |
Not clear |
| Stéphane Marinesco, Kristy L Duran, William G Wrigh. Evolution of learning in three aplysiid species: differences in heterosynaptic plasticity contrast with conservation in serotonergic pathways. The Journal of physiology. vol 550. issue Pt 1. 2004-03-05. PMID:12740422. |
because sensitization in aplysia is strongly correlated with serotonergic (5-ht) neuromodulation, we hypothesized that the observed interspecific variation in sensitization and sn neuromodulation might be correlated with variation in the anatomy and/or functional response of the serotonergic system. |
2004-03-05 |
2023-08-12 |
aplysia |
| Martine Orosco, Claude Rouch, Françoise Beslot, Sébastien Feurte, Alain Regnault, Valérie Daug. Alpha-lactalbumin-enriched diets enhance serotonin release and induce anxiolytic and rewarding effects in the rat. Behavioural brain research. vol 148. issue 1-2. 2004-03-01. PMID:14684242. |
as an index of serotonergic activity, we assessed extracellular 5-ht in response to lac ingestion, using microdialysis, and performed behavioural tests in rats in order to characterise the suggested improvements of mood observed in humans after ingestion of this protein. |
2004-03-01 |
2023-08-12 |
rat |
| L Pinessi, I Rainero, W Valfrè, R Lo Giudice, M Ferrero, C Rivoiro, E Arvat, L Gianotti, P Del Rizzo, P Limon. Abnormal 5-HT1D receptor function in cluster headache: a neuroendocrine study with sumatriptan. Cephalalgia : an international journal of headache. vol 23. issue 5. 2004-02-26. PMID:12780765. |
our results suggest that cerebral serotonergic functions mediated by 5-ht(1d) receptors are altered in patients with episodic cluster headache. |
2004-02-26 |
2023-08-12 |
Not clear |
| Jie Huang, Virginia M Picke. Serotonin transporters (SERTs) within the rat nucleus of the solitary tract: subcellular distribution and relation to 5HT2A receptors. Journal of neurocytology. vol 31. issue 8-9. 2004-02-26. PMID:14501206. |
serotonergic transmission is terminated by serotonin transporter (sert)-mediated uptake following activation of serotonin receptors, several subtypes of which are present in the medial nucleus of the solitary tract (mnts) at the area postrema level. |
2004-02-26 |
2023-08-12 |
rat |
| Tao Chen, Yuan-Xiang Dong, Yun-Qing L. Fos expression in serotonergic neurons in the rat brainstem following noxious stimuli: an immunohistochemical double-labelling study. Journal of anatomy. vol 203. issue 6. 2004-02-24. PMID:14686693. |
in order to detect whether there were different expression patterns of fos protein induced by somatic or visceral noxious stimulation in the serotonergic neurons in the rat brainstem, an immunohistochemical double-labelling technique for serotonin (5-ht) and fos was employed after subcutaneous or stomach injection of formalin. |
2004-02-24 |
2023-08-12 |
rat |
| A W Bergen, M B M van den Bree, M Yeager, R Welch, J K Ganjei, K Haque, S Bacanu, W H Berrettini, D E Grice, D Goldman, C M Bulik, K Klump, M Fichter, K Halmi, A Kaplan, M Strober, J Treasure, B Woodside, W H Kay. Candidate genes for anorexia nervosa in the 1p33-36 linkage region: serotonin 1D and delta opioid receptor loci exhibit significant association to anorexia nervosa. Molecular psychiatry. vol 8. issue 4. 2004-02-20. PMID:12740597. |
serotonergic and opioidergic neurotransmitter system alterations have been observed in people with eating disorders; the genes for the serotonin 1d receptor (htr1d) and the opioid delta receptor (oprd1) are found on chr1p36.3-34.3, a region identified by our group in a linkage analysis of anorexia nervosa (an). |
2004-02-20 |
2023-08-12 |
Not clear |
| Agnieszka Irena Członkowska, Małgorzata Zienowicz, Andrzej Bidziński, Piotr Maciejak, Małgorzata Lehner, Ewa Taracha, Aleksandra Wisłowska, Adam Płaźni. The role of neurosteroids in the anxiolytic,antidepressive- and anticonvulsive effects of selective serotonin reuptake inhibitors. Medical science monitor : international medical journal of experimental and clinical research. vol 9. issue 11. 2004-02-20. PMID:14586292. |
they not only block the serotonin transporter, but also bind to different types of monoaminergic receptors (serotonergic, dopaminergic) and interact with the synthesis of neurosteroids, in this way modifying the excitability of the central nervous system. |
2004-02-20 |
2023-08-12 |
Not clear |
| David Perrin, Julie Mamet, Alain Géloën, Gérard Morel, Yvette Dalmaz, Jean-Marc Pequigno. Sympathetic and brain monoaminergic regulation of energy balance in obesity-resistant rats (Lou/C). Autonomic neuroscience : basic & clinical. vol 109. issue 1-2. 2004-02-20. PMID:14638307. |
to determine the role of sympathetic output and brain monoamines in the different energy balance of lou/c rats, the monoamine contents and activity of rate-limiting enzymes in catecholamine and serotonin biosynthesis were assessed in brain structures involved in energy balance regulation, i.e., brainstem noradrenergic (a6, a5, a2) and serotonergic cell groups (dorsal raphe, and median raphe), and two hypothalamic nuclei (ventromedial nucleus and paraventricular nucleus). |
2004-02-20 |
2023-08-12 |
rat |
| S Shimazu, K Takahata, A Tamashiro, F Yoneda, Y Iida, H Saj. Recovery of motor function and dopaminergic parameters in a mouse model of Parkinson's disease induced by co-administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and diethyldithiocarbamate. Journal of neural transmission (Vienna, Austria : 1996). vol 110. issue 8. 2004-02-19. PMID:12898343. |
on the other hand, the serotonin content increased slightly but significantly after 3 or 6 weeks, suggesting compensatory activation of the serotonergic system against da depletion. |
2004-02-19 |
2023-08-12 |
mouse |
| J Balaji, R Desai, S Mait. Live cell ultraviolet microscopy: a comparison between two- and three-photon excitation. Microscopy research and technique. vol 63. issue 1. 2004-02-11. PMID:14677135. |
surprisingly, for live cell imaging of vesicular serotonin in serotonergic cells, three-photon excitation appears to provide better image contrast than two-photon excitation. |
2004-02-11 |
2023-08-12 |
Not clear |
| J F Rodríguez-Landa, C M Contrera. A review of clinical and experimental observations about antidepressant actions and side effects produced by Hypericum perforatum extracts. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 10. issue 8. 2004-02-11. PMID:14692732. |
although some clinical and experimental studies suggest it has some properties similar to conventional antidepressants, the proposed mechanism of action seems to be multiple: a non-selective blockade of the reuptake of serotonin, noradrenaline and dopamine; an increase in density of serotonergic and dopaminergic receptors and an increased affinity for gabaergic receptors; moreover, the inhibition of monoaminoxidase enzyme activity has been involved. |
2004-02-11 |
2023-08-12 |
Not clear |
| Snezana Kusljic, David L Copolov, Maarten van den Buus. Differential role of serotonergic projections arising from the dorsal and median raphe nuclei in locomotor hyperactivity and prepulse inhibition. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12888784. |
while an involvement of brain serotonin systems in schizophrenia has been suggested by many studies, the relative role of different serotonergic projections in the brain remains unclear. |
2004-02-10 |
2023-08-12 |
rat |
| Akihiko Oshima, Cornelia Flachskamm, Johannes M H M Reul, Florian Holsboer, Astrid C E Linthors. Altered serotonergic neurotransmission but normal hypothalamic-pituitary-adrenocortical axis activity in mice chronically treated with the corticotropin-releasing hormone receptor type 1 antagonist NBI 30775. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12915860. |
owing to the intricate relationship between crh and serotonin (5-ht), we studied the effects of chronic oral treatment of c57bl6/n mice with the crh-r1 antagonist nbi 30775 (formerly known as r121919) on hippocampal serotonergic neurotransmission during basal (on 15th day of treatment) and stress (forced swimming; on 16th day of treatment) conditions by in vivo microdialysis. |
2004-02-10 |
2023-08-12 |
mouse |
| Andrew Holmes, Rebecca J Yang, Klaus-Peter Lesch, Jacqueline N Crawley, Dennis L Murph. Mice lacking the serotonin transporter exhibit 5-HT(1A) receptor-mediated abnormalities in tests for anxiety-like behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 12. 2004-02-10. PMID:12968128. |
the serotonin transporter (5-htt) regulates serotonergic neurotransmission via clearance of extracellular serotonin. |
2004-02-10 |
2023-08-12 |
mouse |