| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kenny J Simansky, Danielle M Nicklou. Parabrachial infusion of D-fenfluramine reduces food intake. Blockade by the 5-HT(1B) antagonist SB-216641. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888559. |
these data strongly suggest that directly or indirectly activating 5-ht(1b) receptors in the lpbn inhibits feeding and implicates this pontine region in the serotonergic regulation of eating and satiation. |
2002-09-11 |
2023-08-12 |
rat |
| Vincenzo Di Matteo, Marisa Cacchio, Camillo Di Giulio, Ennio Esposit. Role of serotonin(2C) receptors in the control of brain dopaminergic function. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888564. |
there is substantial evidence that the functional status of mesocorticolimbic dopaminergic (da) system originating in the ventral tegmental area (vta) is under a phasic and tonic inhibitory control by the serotonergic system, which acts by stimulating serotonin(2c) (5-ht(2c)) receptor subtypes. |
2002-09-11 |
2023-08-12 |
human |
| Pallab Seth, Survjit Cheeta, Sonia Tucci, Sandra E Fil. Nicotinic--serotonergic interactions in brain and behaviour. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888570. |
as yet, there is little firm evidence for nicotinic receptors on serotonergic terminals and thus nicotine's effects on 5-ht may not necessarily be directly mediated, but there is strong evidence that the 5-ht tone plays a permissive role in nicotine's effects. |
2002-09-11 |
2023-08-12 |
Not clear |
| Kevin C F Fone, Ian A Topha. Alteration in 5-hydroxytryptamine agonist-induced behaviour following a corticosterone implant in adult rats. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888572. |
hypothalamic 5-ht receptors mediating corticosterone- and 5-ht(1a) receptors, whether on serotonergic nerve terminals or postsynaptic neurones, were downregulated by corticosterone treatment. |
2002-09-11 |
2023-08-12 |
rat |
| A C Parrot. Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity. Pharmacology, biochemistry, and behavior. vol 71. issue 4. 2002-09-11. PMID:11888574. |
recreational ecstasy/mdma, the serotonin syndrome, and serotonergic neurotoxicity. |
2002-09-11 |
2023-08-12 |
Not clear |
| Ji Ying Sze, Shenyuan Zhang, Jie Li, Gary Ruvku. The C. elegans POU-domain transcription factor UNC-86 regulates the tph-1 tryptophan hydroxylase gene and neurite outgrowth in specific serotonergic neurons. Development (Cambridge, England). vol 129. issue 16. 2002-09-11. PMID:12135927. |
however, unc-86-null mutations do not impair the ability of nsm to reuptake serotonin released from the adf serotonergic chemosensory neurons and this serotonin reuptake is sensitive to the serotonin reuptake block drugs imipramine and fluoxetine, demonstrating that serotonin synthesis and reuptake is regulated by distinct factors. |
2002-09-11 |
2023-08-12 |
caenorhabditis_elegans |
| N K Popova, T G Amstislavskay. Involvement of the 5-HT(1A) and 5-HT(1B) serotonergic receptor subtypes in sexual arousal in male mice. Psychoneuroendocrinology. vol 27. issue 5. 2002-09-09. PMID:11965359. |
involvement of the 5-ht(1a) and 5-ht(1b) serotonergic receptor subtypes in sexual arousal in male mice. |
2002-09-09 |
2023-08-12 |
mouse |
| A Frazer, S Benmansou. Delayed pharmacological effects of antidepressants. Molecular psychiatry. vol 7 Suppl 1. 2002-09-04. PMID:11986992. |
results are presented showing that when selective inhibitors of serotonin or norepinephrine uptake are given for such time periods, they still produce selective effects on serotonergic or noradrenergic parameters. |
2002-09-04 |
2023-08-12 |
rat |
| Olivia Lehmann, Fabrice Bertrand, Hélène Jeltsch, Martine Morer, Christine Lazarus, Bruno Will, Jean-Christophe Casse. 5,7-DHT-induced hippocampal 5-HT depletion attenuates behavioural deficits produced by 192 IgG-saporin lesions of septal cholinergic neurons in the rat. The European journal of neuroscience. vol 15. issue 12. 2002-09-04. PMID:12099905. |
this observation is in close concordance with data showing that a reduction of the serotonergic tone, by pharmacological activation of somatodendritic 5-ht(1a) receptors on raphe neurons, attenuates the cognitive disturbances produced by the intrahippocampal infusion of the antimuscarinic drug, scopolamine. |
2002-09-04 |
2023-08-12 |
rat |
| R Spille. Pharmacotherapy: non-serotonergic mechanisms. Gut. vol 51 Suppl 1. 2002-08-29. PMID:12077075. |
noradrenaline reuptake inhibitors appear to be more effective than selective serotonergic reuptake inhibitors, suggesting that pathways other than those modulated by serotonin may be involved in visceral sensation. |
2002-08-29 |
2023-08-12 |
Not clear |
| Q G. Neuromodulatory transmitter systems in the cortex and their role in cortical plasticity. Neuroscience. vol 111. issue 4. 2002-08-28. PMID:12031406. |
among the neuromodulatory transmitter receptor subtypes, cholinergic m(1), noradrenergic beta(1) and serotonergic 5-ht(2c) receptors appear to be more important than other receptor subtypes for cortical plasticity. |
2002-08-28 |
2023-08-12 |
Not clear |
| R Shiloh, Z Zemishlany, D Aizenberg, A Valevski, L Bodinger, H Munitz, A Weizma. Mianserin or placebo as adjuncts to typical antipsychotics in resistant schizophrenia. International clinical psychopharmacology. vol 17. issue 2. 2002-08-26. PMID:11890187. |
the beneficial effect of atypical antipsychotic drugs (apds) in treatment-resistant schizophrenia patients has been attributed, mostly, to their relatively high serotonergic (5-ht)2 to dopaminergic (d)2 receptor blockade ratio. |
2002-08-26 |
2023-08-12 |
Not clear |
| Darakhshan J Haleem, Zafar S Saify, Sonia Siddiqui, Farhat Batool, Mohammad A Halee. Pre- and postsynaptic responses to 1-(1-naphthylpiperazine) following adaptation to stress in rats. Progress in neuro-psychopharmacology & biological psychiatry. vol 26. issue 1. 2002-08-20. PMID:11853106. |
serotonergic and motor responses to 1-np in unrestrained and repeatedly restrained adapted rats were compared by injecting the drug at a dose of 5 mg/kg, a dose that above results suggested would not produce maximal effects on 5-ht metabolism or motor activity. |
2002-08-20 |
2023-08-12 |
rat |
| K G Harikumar, A Chattopadhya. Modulation of antagonist binding to serotonin1A receptors from bovine hippocampus by metal ions. Cellular and molecular neurobiology. vol 21. issue 5. 2002-08-20. PMID:11860184. |
our results also show that the specific antagonist p-mppf binds to all available receptors in the bovine hippocampal membrane irrespective of their state of g-protein coupling and other serotonergic ligands such as 5-ht and oh-dpat effectively compete with the specific antagonist [3h]p-mppf. |
2002-08-20 |
2023-08-12 |
cattle |
| Osamu Ohmori, Takahiro Shinkai, Hiroko Hori, Jun Nakamur. Genetic association analysis of 5-HT(6) receptor gene polymorphism (267C/T) with tardive dyskinesia. Psychiatry research. vol 110. issue 2. 2002-08-20. PMID:12057822. |
possible involvement of serotonergic (5-hydroxytryptamine: 5-ht) receptors in the pathophysiology of tardive dyskinesia (td) has been suggested. |
2002-08-20 |
2023-08-12 |
human |
| Ashwin A Patkar, Wade H Berrettini, Margret Hoehe, Charles C Thornton, Edward Gottheil, Kevin Hill, Stephen P Weinstei. Serotonin transporter polymorphisms and measures of impulsivity, aggression, and sensation seeking among African-American cocaine-dependent individuals. Psychiatry research. vol 110. issue 2. 2002-08-20. PMID:12057823. |
considerable evidence indicates that serotonergic mechanisms, particularly the serotonin transporter (5htt), may mediate central effects of cocaine and may also be involved in impulsive and aggressive behavior. |
2002-08-20 |
2023-08-12 |
human |
| Joseph Weidenfeld, Shaul Feldman, Anna Itzik, Louis D Van de Kar, Michael E Newma. Evidence for a mutual interaction between noradrenergic and serotonergic agonists in stimulation of ACTH and corticosterone secretion in the rat. Brain research. vol 941. issue 1-2. 2002-08-14. PMID:12031553. |
we investigated the mutual interactions between hypothalamic norepinephrine (ne) and serotonin (5-ht) in mediating the acth and corticosterone responses to direct stimulation of the paraventricular nucleus (pvn) with adrenergic and serotonergic agonists. |
2002-08-14 |
2023-08-12 |
rat |
| Joseph Weidenfeld, Shaul Feldman, Anna Itzik, Louis D Van de Kar, Michael E Newma. Evidence for a mutual interaction between noradrenergic and serotonergic agonists in stimulation of ACTH and corticosterone secretion in the rat. Brain research. vol 941. issue 1-2. 2002-08-14. PMID:12031553. |
the hormone responses to the intrahypothalamic injection of the alpha1-adrenergic agonist phenylephrine (20 nmol/2 microl) were significantly reduced by prior depletion of hypothalamic 5-ht with intra-pvn injection of the serotonergic neurotoxin 5,7-dihydroxytryptamine (5,7-dht), but not after depletion of hypothalamic ne by intra-pvn injection of the noradrenergic neurotoxin 6-hydroxydopamine (6-ohda). |
2002-08-14 |
2023-08-12 |
rat |
| Lotte De Groote, Berend Olivier, Herman G M Westenber. The effects of selective serotonin reuptake inhibitors on extracellular 5-HT levels in the hippocampus of 5-HT(1B) receptor knockout mice. European journal of pharmacology. vol 439. issue 1-3. 2002-08-08. PMID:11937097. |
in conclusion, the differences in hippocampal 5-ht output between wildtype and 5-ht(1b) knockout mice after local or systemic administration of selective 5-ht reuptake inhibitors show that 5-ht(1b) autoreceptors play a significant role in the inhibition of 5-ht release at serotonergic nerve terminals. |
2002-08-08 |
2023-08-12 |
mouse |
| Christian P Müller, Robert J Carey, Maria A De Souza Silva, Gerhard Jocham, Joseph P Husto. Cocaine increases serotonergic activity in the hippocampus and nucleus accumbens in vivo: 5-HT1a-receptor antagonism blocks behavioral but potentiates serotonergic activation. Synapse (New York, N.Y.). vol 45. issue 2. 2002-08-08. PMID:12112399. |
neuronal activity in the hippocampus and the nucleus accumbens (nac) depend on serotonergic (5-ht) transmission. |
2002-08-08 |
2023-08-12 |
rat |