| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David M Compton, Kerri L Dietrich, Melissa C Selinger, Erin K Test. 5-methoxy-N,N-di(iso)propyltryptamine hydrochloride (Foxy)-induced cognitive deficits in rat after exposure in adolescence. Physiology & behavior. vol 103. issue 2. 2011-07-15. PMID:21295050. |
detected reductions in serotonin activity in the forebrain similar to the effects of extensively investigated compounds such as methylenedioxymethamphetamine (mdma), suggest that 5-meo-dipt may produce its adverse effects by compromising serotonergic systems in the brain. |
2011-07-15 |
2023-08-12 |
rat |
| Tiago Souza dos Santos, Cristiane Meneghelli, Alexandre A Hoeller, Marta Aparecida Paschoalini, Lut Arckens, Cilene Lino-de-Oliveira, José Marino-Net. Behavioral profile and Fos activation of serotonergic and non-serotonergic raphe neurons after central injections of serotonin in the pigeon (Columba livia). Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21310184. |
behavioral profile and fos activation of serotonergic and non-serotonergic raphe neurons after central injections of serotonin in the pigeon (columba livia). |
2011-07-15 |
2023-08-12 |
pigeon |
| Tiago Souza dos Santos, Cristiane Meneghelli, Alexandre A Hoeller, Marta Aparecida Paschoalini, Lut Arckens, Cilene Lino-de-Oliveira, José Marino-Net. Behavioral profile and Fos activation of serotonergic and non-serotonergic raphe neurons after central injections of serotonin in the pigeon (Columba livia). Behavioural brain research. vol 220. issue 1. 2011-07-15. PMID:21310184. |
these data indicate that hyperdipsic and hypnogenic effects of icv 5-ht in pigeons may result from the inhibition of a tonic activity of serotonergic neurons, which is possibly relevant to the control of postprandial behaviors, and that these relationships are shared functional traits of the serotonergic circuits in amniotes. |
2011-07-15 |
2023-08-12 |
pigeon |
| Tillmann Weber, Gerald Böhm, Elke Hermann, Günther Schütz, Kai Schönig, Dusan Bartsc. Inducible gene manipulations in serotonergic neurons. Frontiers in molecular neuroscience. vol 2. 2011-07-14. PMID:19936315. |
an impairment of the serotonergic (5-ht) system has been implicated in the etiology of many neuropsychiatric disorders. |
2011-07-14 |
2023-08-12 |
mouse |
| Tillmann Weber, Gerald Böhm, Elke Hermann, Günther Schütz, Kai Schönig, Dusan Bartsc. Inducible gene manipulations in serotonergic neurons. Frontiers in molecular neuroscience. vol 2. 2011-07-14. PMID:19936315. |
to address the lack of instruments for the molecular dissection of gene function in serotonergic neurons we have developed a new mouse transgenic tool that allows inducible cre-mediated recombination of genes selectively in 5-ht neurons of all raphe nuclei. |
2011-07-14 |
2023-08-12 |
mouse |
| Tillmann Weber, Gerald Böhm, Elke Hermann, Günther Schütz, Kai Schönig, Dusan Bartsc. Inducible gene manipulations in serotonergic neurons. Frontiers in molecular neuroscience. vol 2. 2011-07-14. PMID:19936315. |
to illustrate the versatility of this new tool, we show that brainbow-1.0l(tph2-creert2) mice display highly efficient recombination in serotonergic neurons with individual 5-ht neurons labeling with multiple distinct fluorescent colors. |
2011-07-14 |
2023-08-12 |
mouse |
| Friederike Klempin, Harish Babu, Davide De Pietri Tonelli, Edson Alarcon, Klaus Fabel, Gerd Kemperman. Oppositional effects of serotonin receptors 5-HT1a, 2, and 2c in the regulation of adult hippocampal neurogenesis. Frontiers in molecular neuroscience. vol 3. 2011-07-14. PMID:20721314. |
rather, the delayed response to serotonergic drugs with respect to endpoints downstream of the immediate receptor activity is largely due to the initially antagonistic and un-balanced action of different 5-ht receptors. |
2011-07-14 |
2023-08-12 |
Not clear |
| Laura A Smit-Rigter, Wytse J Wadman, Johannes A van Hoof. Impaired Social Behavior in 5-HT(3A) Receptor Knockout Mice. Frontiers in behavioral neuroscience. vol 4. 2011-07-14. PMID:21103015. |
these results indicate that the 5-ht(3a) knockout mouse displays impaired social behavior with specific changes in males and females, reminiscent to other mouse models in which serotonergic signaling is disturbed in the developing brain. |
2011-07-14 |
2023-08-12 |
mouse |
| Soo-Hyun Park, Yun-Beom Sim, Soon-Sung Lim, Jin-Kyu Kim, Jin-Koo Lee, Hong-Won Su. Antinociception effect and mechanisms of campanula punctata extract in the mouse. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. vol 14. issue 5. 2011-07-14. PMID:21165326. |
however, naloxone (opioid receptor antagonist) or methysergide (5-ht serotonergic receptor antagonist) did not affect antinociception induced by campanula punctata extract in the writhing test. |
2011-07-14 |
2023-08-12 |
mouse |
| Debasish Sanyal, Suddhendu Chakraborty, Ranjan Bhattacharyy. An interesting case of serotonin syndrome precipitated by escitalopram. Indian journal of pharmacology. vol 42. issue 6. 2011-07-14. PMID:21189920. |
serotonin syndrome is a known entity, which occurs with multiple drugs acting on serotonergic receptors. |
2011-07-14 |
2023-08-12 |
Not clear |
| Marcel D Waldinge. Toward evidence-based genetic research on lifelong premature ejaculation: a critical evaluation of methodology. Korean journal of urology. vol 52. issue 1. 2011-07-14. PMID:21344023. |
this means that serotonergic genetic polymorphisms may only be found in men with pe who respond with an ejaculation delay treatment with a selective serotonin reuptake inhibitor. |
2011-07-14 |
2023-08-12 |
human |
| A K Agarwal, A Khali. Obsessive - compulsive symptoms during clozapine treatment. Indian journal of psychiatry. vol 39. issue 3. 2011-07-14. PMID:21584085. |
since clozapine is a potent 5-ht(2) receptor blocker, role of serotonergic systems in the development of obsessive-compulsive symptoms may be considered. |
2011-07-14 |
2023-08-12 |
Not clear |
| Holger Brockmann, Astrid Zobel, Anna Schuhmacher, Marcel Daamen, Alexius Joe, Kim Biermann, Sibylle G Schwab, Hans-Juergen Biersack, Wolfgang Maier, Henning Boecke. Influence of 5-HTTLPR polymorphism on resting state perfusion in patients with major depression. Journal of psychiatric research. vol 45. issue 4. 2011-07-13. PMID:20934189. |
the serotonergic system is the principal target for pharmacological treatment in mdd and the functional variable serotonin promoter polymorphism (5-httlpr) influences susceptibility, course and treatment response of mdd. |
2011-07-13 |
2023-08-12 |
Not clear |
| Jun-Xu Li, Wouter Koek, Kenner C Rice, Charles P Franc. Effects of direct- and indirect-acting serotonin receptor agonists on the antinociceptive and discriminative stimulus effects of morphine in rhesus monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 36. issue 5. 2011-07-13. PMID:21209613. |
serotonergic (5-ht) systems modulate pain, and drugs acting on 5-ht systems are used with opioids to treat pain. |
2011-07-13 |
2023-08-12 |
monkey |
| Lynda Uphouse, Danyeal Heckard, Cindy Hiegel, Jutatip Guptarak, Sharmin Maswoo. Tropisetron increases the inhibitory effect of mild restraint on lordosis behavior of hormonally primed, ovariectomized rats. Behavioural brain research. vol 219. issue 2. 2011-07-13. PMID:21238491. |
however, modulation of the serotonergic (5-ht) system alters this resistance to stress. |
2011-07-13 |
2023-08-12 |
rat |
| S J Bang, K G Common. Age-dependent effects of initial exposure to nicotine on serotonin neurons. Neuroscience. vol 179. 2011-07-13. PMID:21277949. |
growing evidence suggests that serotonergic (5-ht) neurotransmission may contribute to the initiation and maintenance of addictive behavior. |
2011-07-13 |
2023-08-12 |
rat |
| Jesse W Richardson-Jones, Caryne P Craige, Thanh H Nguyen, Hank F Kung, Alain M Gardier, Alex Dranovsky, Denis J David, Bruno P Guiard, Sheryl G Beck, René Hen, E David Leonard. Serotonin-1A autoreceptors are necessary and sufficient for the normal formation of circuits underlying innate anxiety. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 16. 2011-06-30. PMID:21508226. |
the inhibitory serotonin-1a (5-ht(1a)) receptor exists in two separate populations with distinct effects on serotonergic signaling: (1) an autoreceptor that limits 5-ht release throughout the brain and (2) a heteroreceptor that mediates inhibitory responses to released 5-ht. |
2011-06-30 |
2023-08-12 |
mouse |
| Uday Gaikwad, Milind Parl. Combination of aripiprazole and ethanol attenuates marble-burying behavior in mice. Acta poloniae pharmaceutica. vol 68. issue 3. 2011-06-28. PMID:21648199. |
5-hydroxytryptamine (5-ht) abnormalities may be involved in ocd, and further, cause changes in serotonergic transmission that may have direct or indirect effects on the neuronal firing of other neuromodulators affecting thoughts, feelings and behaviors. |
2011-06-28 |
2023-08-12 |
mouse |
| Jessica E Duffy-Whritenour, Rebecca Z Kurtzman, Sarah Kennedy, Judith T Zelikof. Non-coplanar polychlorinated biphenyl (PCB)-induced immunotoxicity is coincident with alterations in the serotonergic system. Journal of immunotoxicology. vol 7. issue 4. 2011-06-27. PMID:20843273. |
because the serotonergic nervous system has been shown to be involved in the regulation of some immune responses, and also serves as a sensitive target for pcbs, the relationship (if any) between non-coplanar pcb exposure, immune responsiveness and the neurotransmitter serotonin (5-ht) was examined. |
2011-06-27 |
2023-08-12 |
Not clear |
| Virginie Dolmazon, Natalia Alenina, Suzy Markossian, Jimmy Mancip, Yvonne van de Vrede, Emeline Fontaine, Colette Dehay, Henry Kennedy, Michael Bader, Pierre Savatier, Agnieszka Berna. Forced expression of LIM homeodomain transcription factor 1b enhances differentiation of mouse embryonic stem cells into serotonergic neurons. Stem cells and development. vol 20. issue 2. 2011-06-24. PMID:20649486. |
clones expressing lmx1b at a low level showed increased neurogenesis and elevated production of neurons expressing serotonin, serotonin transporter, tryptophan hydroxylase 2, and transcription factor pet1, the landmarks of serotonergic differentiation. |
2011-06-24 |
2023-08-12 |
mouse |