| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hans Rollema, Gary G Wilson, Theodore C Lee, Joost H A Folgering, Gunnar Fli. Effect of co-administration of varenicline and antidepressants on extracellular monoamine concentrations in rat prefrontal cortex. Neurochemistry international. vol 58. issue 1. 2011-03-31. PMID:21056607. |
since varenicline neither diminished nor potentiated sertraline- or clorgyline-induced increases in neurotransmitter levels, combining varenicline with serotonergic antidepressants is unlikely to cause excessive serotonin release or to attenuate antidepressant efficacy via effects on cortical serotonin, dopamine or norepinephrine release. |
2011-03-31 |
2023-08-12 |
rat |
| Fabiana B Kohlrausch, Angélica Salatino-Oliveira, Clarissa S Gama, Maria Inês Lobato, Paulo Belmonte-de-Abreu, Mara H Hut. Influence of serotonin transporter gene polymorphisms on clozapine response in Brazilian schizophrenics. Journal of psychiatric research. vol 44. issue 16. 2011-03-29. PMID:20452607. |
clozapine's action results from interactions between dopaminergic and serotonergic neurotransmitter systems and since clozapine appears to exert its effect strongly through the serotonergic systems, alterations in serotonin synaptic levels may influence antipsychotic response. |
2011-03-29 |
2023-08-12 |
Not clear |
| Yu-Ren Chen, Ya-Ping Huang, Shan-Ju Lin, Tsao-Hsiang Kuan, Chin-Hsien Li. Effectiveness of quetiapine for poststroke pathological laughing: case report and review of the literature. Clinical neuropharmacology. vol 33. issue 6. 2011-03-29. PMID:21079459. |
dysregulation of serotonergic system has been proposed as one of the possible mechanisms resulting in this condition, and selective serotonin reuptake inhibitors have been used for treatment of pl with variable effects. |
2011-03-29 |
2023-08-12 |
Not clear |
| Andrew A Monte, Ryan Chuang, Michael Bodme. Dextromethorphan, chlorphenamine and serotonin toxicity: case report and systematic literature review. British journal of clinical pharmacology. vol 70. issue 6. 2011-03-28. PMID:21175434. |
chlorphenamine is a serotonergic medication and combinations of chlorphenamine and dextromethorphan may be dangerous in overdose due to an increased risk of serotonin toxicity. |
2011-03-28 |
2023-08-12 |
Not clear |
| Chikara Abe, Kunihiko Tanaka, Chihiro Iwata, Hironobu Morit. Vestibular-mediated increase in central serotonin plays an important role in hypergravity-induced hypophagia in rats. Journal of applied physiology (Bethesda, Md. : 1985). vol 109. issue 6. 2011-03-25. PMID:20847126. |
because the vestibular nucleus contains serotonergic neurons and because serotonin (5-ht) is a key neurotransmitter in hypophagia, with possible involvement in motion sickness, we hypothesized that central 5-ht increases during hypergravity and induces hypophagia. |
2011-03-25 |
2023-08-12 |
rat |
| Marie-Bernadette Assié, Laurent Bardin, Agnès L Auclair, Elisabeth Carilla-Durand, Ronan Depoortère, Wouter Koek, Mark S Kleven, Francis Colpaert, Bernard Vacher, Adrian Newman-Tancred. F15599, a highly selective post-synaptic 5-HT(1A) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity. The international journal of neuropsychopharmacology. vol 13. issue 10. 2011-03-18. PMID:20059805. |
f15599, a highly selective post-synaptic 5-ht(1a) receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity. |
2011-03-18 |
2023-08-12 |
rat |
| Sujatha Kannan, Fadoua Saadani-Makki, Bindu Balakrishnan, Hui Dai, Pulak K Chakraborty, James Janisse, Otto Muzik, Roberto Romero, Diane C Chugan. Decreased cortical serotonin in neonatal rabbits exposed to endotoxin in utero. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. vol 31. issue 2. 2011-03-17. PMID:20827261. |
serotonin is crucial for regulating maturation in the developing brain, and maternal inflammation may result in disruption of the serotonergic system in the perinatal period. |
2011-03-17 |
2023-08-12 |
Not clear |
| Stefano Pallanti, Silvia Bernardi, Andrea Allen, Eric Hollande. Serotonin function in pathological gambling: blunted growth hormone response to sumatriptan. Journal of psychopharmacology (Oxford, England). vol 24. issue 12. 2011-03-16. PMID:19825906. |
its phenomenology cannot be reduced to a single neurobiological dysfunction; instead, it has been conceived as a complex chain of events in which the serotonergic system (5-ht) has often been suggested as one of the most prominent involved. |
2011-03-16 |
2023-08-12 |
human |
| R Berardelli, E Margarito, F Ghiggia, A Picu, M Balbo, L Bonelli, R Giordano, I Karamouzis, M Bo, E Ghigo, E Arva. Neuroendocrine effects of citalopram, a selective serotonin re-uptake inhibitor, during lifespan in humans. Journal of endocrinological investigation. vol 33. issue 9. 2011-03-14. PMID:20414043. |
in humans, serotonergic agonists increase prl, acth, and cortisol, while serotonin (5ht) influence on gh is controversial. |
2011-03-14 |
2023-08-12 |
Not clear |
| Julie A Wixey, Hanna E Reinebrant, Kathryn M Bulle. Inhibition of neuroinflammation prevents injury to the serotonergic network after hypoxia-ischemia in the immature rat brain. Journal of neuropathology and experimental neurology. vol 70. issue 1. 2011-03-07. PMID:21157380. |
interruption of the central serotonergic (5-hydroxytryptamine [5-ht]) system can lead to numerous functional deficits, many of which match those in human preterm neonates exposed to hi. |
2011-03-07 |
2023-08-12 |
human |
| Julie A Wixey, Hanna E Reinebrant, Kathryn M Bulle. Inhibition of neuroinflammation prevents injury to the serotonergic network after hypoxia-ischemia in the immature rat brain. Journal of neuropathology and experimental neurology. vol 70. issue 1. 2011-03-07. PMID:21157380. |
the concurrent improvement in serotonergic outcomes suggests that inhibition of neuroinflammation prevented damage to the serotonergic neurons rather than affected the regulation of 5-ht or serotonin transporter. |
2011-03-07 |
2023-08-12 |
human |
| Anton Y Bespalov, Marcel M van Gaalen, Gerhard Gros. Antidepressant treatment in anxiety disorders. Current topics in behavioral neurosciences. vol 2. 2011-03-07. PMID:21309117. |
broad efficacy of selective serotonin reuptake inhibitors suggests the importance of enhanced serotonergic function of the anxiolytic properties of current antidepressants. |
2011-03-07 |
2023-08-12 |
human |
| Helen Blair Simpso. Pharmacological treatment of obsessive-compulsive disorder. Current topics in behavioral neurosciences. vol 2. 2011-03-07. PMID:21309125. |
the only medications which have proved effective for ocd in multisite randomized controlled trials are serotonin reuptake inhibitors, which include clomipramine (a noradrenergic and serotonergic reuptake inhibitor) and the selective serotonin reuptake inhibitors. |
2011-03-07 |
2023-08-12 |
Not clear |
| Y Yao, P J Bergold, N J Peningto. Acute Ca(2+)-dependent desensitization of 5-HT(1A) receptors is mediated by activation of protein kinase A (PKA) in rat serotonergic neurons. Neuroscience. vol 169. issue 1. 2011-03-04. PMID:20423724. |
acute ca(2+)-dependent desensitization of 5-ht(1a) receptors is mediated by activation of protein kinase a (pka) in rat serotonergic neurons. |
2011-03-04 |
2023-08-12 |
rat |
| Masaru Tanaka, Gyula Telegd. Involvement of adrenergic and serotonergic receptors in antidepressant-like effect of urocortin 3 in a modified forced swimming test in mice. Brain research bulletin. vol 77. issue 5. 2011-03-03. PMID:18793704. |
mice were pretreated with a non-selective α-adrenergic receptor antagonist, phenoxybenzamine, an α(1)/α(2β)-adrenergic receptor antagonist, prazosin, an α(2)-adrenergic receptor antagonist, yohimbine, a mixed 5-ht(1)/5-ht(2) serotonergic receptor antagonist, methysergide, a non-selective 5-ht(2) serotonergic receptor antagonist, cyproheptadine or a β-adrenergic receptor antagonist, propranolol. |
2011-03-03 |
2023-08-12 |
mouse |
| Héctor Isaac Rocha-González, Everardo Blaisdell-López, Vinicio Granados-Soto, Andrés Navarret. Antinociceptive effect of 7-hydroxy-3,4-dihydrocadalin isolated from Heterotheca inuloides: role of peripheral 5-HT₁ serotonergic receptors. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20863828. |
moreover, data indicate that 7-hydroxy-3,4-dihydrocadalin is partly responsible of this pharmacological activity, and suggest that 5-ht(1a), 5-ht(1b), and 5-ht(1d) serotonergic, but not opioid, receptors participate in the antinociceptive effect of this drug. |
2011-03-03 |
2023-08-12 |
Not clear |
| Melik Seyrek, Serdar Kahraman, Mehmet Salih Deveci, Ozgur Yesilyurt, Ahmet Dogru. Systemic cannabinoids produce CB₁-mediated antinociception by activation of descending serotonergic pathways that act upon spinal 5-HT(7) and 5-HT(2A) receptors. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20868676. |
systemic cannabinoids produce cb₁-mediated antinociception by activation of descending serotonergic pathways that act upon spinal 5-ht(7) and 5-ht(2a) receptors. |
2011-03-03 |
2023-08-12 |
mouse |
| Melik Seyrek, Serdar Kahraman, Mehmet Salih Deveci, Ozgur Yesilyurt, Ahmet Dogru. Systemic cannabinoids produce CB₁-mediated antinociception by activation of descending serotonergic pathways that act upon spinal 5-HT(7) and 5-HT(2A) receptors. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20868676. |
we evaluated the role of descending serotonergic pathways and spinal 5-ht₇ and 5-ht(2a) receptors in comparison to that of 5-ht(1a) and 5-ht₃ receptors in the antinociceptive effects of systemically administered cannabinoids. |
2011-03-03 |
2023-08-12 |
mouse |
| Melik Seyrek, Serdar Kahraman, Mehmet Salih Deveci, Ozgur Yesilyurt, Ahmet Dogru. Systemic cannabinoids produce CB₁-mediated antinociception by activation of descending serotonergic pathways that act upon spinal 5-HT(7) and 5-HT(2A) receptors. European journal of pharmacology. vol 649. issue 1-3. 2011-03-03. PMID:20868676. |
these findings suggest that systemically administered cannabinoids interact with descending serotonergic pathways via cb₁-mediated mechanisms and exert a central antinociceptive effect involving spinal 5-ht₇ and 5-ht(2a) receptors. |
2011-03-03 |
2023-08-12 |
mouse |
| S Martin, C Lino-de-Oliveira, S R L Joca, R Weffort de Oliveira, M B Echeverry, C A Da Silva, L Pardo, W Stühmer, E D Be. Eag 1, Eag 2 and Kcnn3 gene brain expression of isolated reared rats. Genes, brain, and behavior. vol 9. issue 8. 2011-03-02. PMID:20662937. |
as the long-lasting alterations in emotional and behavioral regulation after stress have been related to changes in serotonergic neurotransmission, expressions of serotonin htr1a and htr2a receptors in male wistar rats' brain were also investigated. |
2011-03-02 |
2023-08-12 |
rat |