| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sandrine M Géranton, Keri K Tochiki, Winnie Wy Chiu, Sarah A Stuart, Stephen P Hun. Injury induced activation of extracellular signal-regulated kinase (ERK) in the rat rostral ventromedial medulla (RVM) is age dependant and requires the lamina I projection pathway. Molecular pain. vol 6. 2011-01-03. PMID:20840753. |
finally, the percentage of perk expressing neurones that were also serotonergic was always around 60%, independent of pain state and age, indicating an important role for serotonin in descending controls of pain states. |
2011-01-03 |
2023-08-12 |
rat |
| Masaya Segaw. [Walking abnormalities in children]. Brain and nerve = Shinkei kenkyu no shinpo. vol 62. issue 11. 2011-01-03. PMID:21068458. |
walking is a spontaneous movement termed locomotion that is promoted by activation of antigravity muscles by serotonergic (5ht) neurons. |
2011-01-03 |
2023-08-12 |
Not clear |
| Ksenija Vucurovic, Thierry Gallopin, Isabelle Ferezou, Armelle Rancillac, Pascal Chameau, Johannes A van Hooft, Hélène Geoffroy, Hannah Monyer, Jean Rossier, Tania Vitali. Serotonin 3A receptor subtype as an early and protracted marker of cortical interneuron subpopulations. Cerebral cortex (New York, N.Y. : 1991). vol 20. issue 10. 2010-12-28. PMID:20083553. |
to identify neocortical neurons expressing the type 3 serotonergic receptor, here we used transgenic mice expressing the enhanced green fluorescent protein (gfp) under the control of the 5-ht(3a) promoter (5-ht(3a):gfp mice). |
2010-12-28 |
2023-08-12 |
mouse |
| Juliano C Capra, Mauricio P Cunha, Daniele G Machado, Andrea D E Zomkowski, Beatriz G Mendes, Adair Roberto S Santos, Moacir G Pizzolatti, Ana Lúcia S Rodrigue. Antidepressant-like effect of scopoletin, a coumarin isolated from Polygala sabulosa (Polygalaceae) in mice: evidence for the involvement of monoaminergic systems. European journal of pharmacology. vol 643. issue 2-3. 2010-12-28. PMID:20599906. |
the results indicate that its antidepressant-like effect is dependent on the serotonergic (5-ht(2a) receptors), noradrenergic (alpha(1)- and alpha(2)-adrenoceptors) and dopaminergic (dopamine d(1) and d(2) receptors) systems. |
2010-12-28 |
2023-08-12 |
mouse |
| Ali G Fenstermaker, Asheeta A Prasad, Ahmad Bechara, Youri Adolfs, Fadel Tissir, Andre Goffinet, Yimin Zou, R Jeroen Pasterkam. Wnt/planar cell polarity signaling controls the anterior-posterior organization of monoaminergic axons in the brainstem. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 47. 2010-12-27. PMID:21106844. |
monoaminergic neurons [serotonergic (5-ht) and dopaminergic (mdda)] in the brainstem project axons along the anterior-posterior axis. |
2010-12-27 |
2023-08-12 |
mouse |
| Claudia Kriegebaum, Ning-Ning Song, Lise Gutknecht, Ying Huang, Angelika Schmitt, Andreas Reif, Yu-Qiang Ding, Klaus-Peter Lesc. Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life. Neurochemistry international. vol 57. issue 5. 2010-12-22. PMID:20599453. |
brain-specific conditional and time-specific inducible tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life. |
2010-12-22 |
2023-08-12 |
mouse |
| Claudia Kriegebaum, Ning-Ning Song, Lise Gutknecht, Ying Huang, Angelika Schmitt, Andreas Reif, Yu-Qiang Ding, Klaus-Peter Lesc. Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life. Neurochemistry international. vol 57. issue 5. 2010-12-22. PMID:20599453. |
these findings confirm the specificity of tph2 in brain 5-ht synthesis across the lifespan, yet also suggest that neither developmental nor adult 5-ht synthesis is required for the expression of genes specific for serotonergic signalling. |
2010-12-22 |
2023-08-12 |
mouse |
| Claudia Kriegebaum, Ning-Ning Song, Lise Gutknecht, Ying Huang, Angelika Schmitt, Andreas Reif, Yu-Qiang Ding, Klaus-Peter Lesc. Brain-specific conditional and time-specific inducible Tph2 knockout mice possess normal serotonergic gene expression in the absence of serotonin during adult life. Neurochemistry international. vol 57. issue 5. 2010-12-22. PMID:20599453. |
the formation of the serotonergic system thus seems to be a preserved expressional pattern due to intrinsic cellular programs which occurs also in the absence of its key molecule, namely 5-ht. |
2010-12-22 |
2023-08-12 |
mouse |
| Christopher M Peters, Ken-ichiro Hayashida, Eric E Ewan, Kunie Nakajima, Hideaki Obata, Qinghao Xu, Tony L Yaksh, James C Eisenac. Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat. Brain research. vol 1352. 2010-12-22. PMID:20637741. |
we also determined the density of serotonergic nerve fibers, serotonin content and the levels of 5-ht3 receptors within the spinal cord at this time point. |
2010-12-22 |
2023-08-12 |
rat |
| Christopher M Peters, Ken-ichiro Hayashida, Eric E Ewan, Kunie Nakajima, Hideaki Obata, Qinghao Xu, Tony L Yaksh, James C Eisenac. Lack of analgesic efficacy of spinal ondansetron on thermal and mechanical hypersensitivity following spinal nerve ligation in the rat. Brain research. vol 1352. 2010-12-22. PMID:20637741. |
in addition, snl did not alter the density of serotonergic fibers or 5-ht3 receptor immunoreactivity or spinal tissue content of 5-ht within the dorsal horn. |
2010-12-22 |
2023-08-12 |
rat |
| Katsutoshi Shioda, Koichi Nisijima, Tatsuki Yoshino, Satoshi Kat. Mirtazapine abolishes hyperthermia in an animal model of serotonin syndrome. Neuroscience letters. vol 482. issue 3. 2010-12-22. PMID:20655983. |
serotonin (5-ht) syndrome is a potentially fatal condition associated with various combinations of serotonergic drugs. |
2010-12-22 |
2023-08-12 |
rat |
| Cristiano Mendes da Silva, Luciano Gonçalves, Raul Manhaes-de-Castro, Maria Inês Nogueir. Postnatal fluoxetine treatment affects the development of serotonergic neurons in rats. Neuroscience letters. vol 483. issue 3. 2010-12-22. PMID:20696211. |
the results show that postnatal chronic treatment with fluoxetine promoted: (1) a smaller body weight increase during the pre-weaning period; (2) smaller number of 5-ht neurons in the dr; (3) smaller 5-ht neuronal cell bodies (area, perimeter and diameter) in the dr and the mnr and (4) diminished serotonergic terminals in the dg. |
2010-12-22 |
2023-08-12 |
rat |
| Cristiano Mendes da Silva, Luciano Gonçalves, Raul Manhaes-de-Castro, Maria Inês Nogueir. Postnatal fluoxetine treatment affects the development of serotonergic neurons in rats. Neuroscience letters. vol 483. issue 3. 2010-12-22. PMID:20696211. |
these data suggest that the development of the serotonergic system was impaired and that early exposure to fluoxetine damaged the morphology of 5-ht neurons in young adult rats. |
2010-12-22 |
2023-08-12 |
rat |
| Cristiano Mendes da Silva, Luciano Gonçalves, Raul Manhaes-de-Castro, Maria Inês Nogueir. Postnatal fluoxetine treatment affects the development of serotonergic neurons in rats. Neuroscience letters. vol 483. issue 3. 2010-12-22. PMID:20696211. |
while these findings are consistent with other work, more studies are needed to better clarify the effects of postnatal chronic treatment with fluoxetine on the serotonergic system and, consequently, on the functions modulated by serotonin. |
2010-12-22 |
2023-08-12 |
rat |
| Janet Best, H Frederik Nijhout, Michael Ree. Serotonin synthesis, release and reuptake in terminals: a mathematical model. Theoretical biology & medical modelling. vol 7. 2010-12-22. PMID:20723248. |
the scientific issues are daunting but important for human health because of the use of selective serotonin reuptake inhibitors and other pharmacological agents to treat disorders in the serotonergic signaling system. |
2010-12-22 |
2023-08-12 |
human |
| Wendi S Neckameye. A trophic role for serotonin in the development of a simple feeding circuit. Developmental neuroscience. vol 32. issue 3. 2010-12-21. PMID:20714156. |
however, using transgenic tools, we show that constitutive knockdown of neuronal 5-ht synthesis to reduce 5-ht levels during central nervous system (cns) development results in increased branching of the serotonergic fibers projecting to the gut, as well as increased size and number of varicosities along the neurite length. |
2010-12-21 |
2023-08-12 |
drosophila_melanogaster |
| Jane E Sarginson, Laura C Lazzeroni, Heather S Ryan, Alan F Schatzberg, Greer M Murph. FKBP5 polymorphisms and antidepressant response in geriatric depression. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 2. 2010-12-20. PMID:19676097. |
these two polymorphisms had previously been reported to predict efficacy in depressed patients treated with selective serotonin reuptake inhibitors such as paroxetine, and those treated with mirtazapine, an agent with both serotonergic and noradrenergic actions. |
2010-12-20 |
2023-08-12 |
Not clear |
| Eun-Joo Shin, Wan Kyunn Whang, Sungun Kim, Jae-Hyung Bach, Jin-Man Kim, Xuan-Khanh Thi Nguyen, Thuy-Ty Lan Nguyen, Bae Dong Jung, Kiyofumi Yamada, Toshitaka Nabeshima, Hyoung-Chun Ki. Parishin C attenuates phencyclidine-induced schizophrenia-like psychosis in mice: involvements of 5-HT1A receptor. Journal of pharmacological sciences. vol 113. issue 4. 2010-12-14. PMID:20644336. |
because ge modulates the serotonergic system and the 5-ht(1a) receptor is an important therapeutic target of schizophrenia, we examined whether parishin c affects phencyclidine-induced abnormal behaviors in mice. |
2010-12-14 |
2023-08-12 |
mouse |
| Belén Rosado, Sylvia García-Belenguer, Jorge Palacio, Gema Chacón, Ainara Villegas, Ana I Alcald. Serotonin transporter activity in platelets and canine aggression. Veterinary journal (London, England : 1997). vol 186. issue 1. 2010-12-13. PMID:19709910. |
several studies have suggested an inhibitory action of the serotonergic system in the regulation of canine aggression, but the role of the serotonin (5-ht) transporter (5-htt) has not been investigated. |
2010-12-13 |
2023-08-12 |
Not clear |
| Belén Rosado, Sylvia García-Belenguer, Jorge Palacio, Gema Chacón, Ainara Villegas, Ana I Alcald. Serotonin transporter activity in platelets and canine aggression. Veterinary journal (London, England : 1997). vol 186. issue 1. 2010-12-13. PMID:19709910. |
these results suggested an association between an alteration in the serotonergic system and canine aggression, possibly mediated by an increased 5-ht transport. |
2010-12-13 |
2023-08-12 |
Not clear |