| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Elizabeth A Daubert, Daniel S Heffron, James W Mandell, Barry G Condro. Serotonergic dystrophy induced by excess serotonin. Molecular and cellular neurosciences. vol 44. issue 3. 2010-09-27. PMID:20394820. |
we demonstrate here that endogenously elevated serotonin in the drosophila cns induces aberrant enlarged varicosities, or spheroids, that are morphologically similar to dystrophic mammalian serotonergic fibers. |
2010-09-27 |
2023-08-12 |
drosophila_melanogaster |
| Elizabeth A Daubert, Daniel S Heffron, James W Mandell, Barry G Condro. Serotonergic dystrophy induced by excess serotonin. Molecular and cellular neurosciences. vol 44. issue 3. 2010-09-27. PMID:20394820. |
in drosophila these spheroids are specific to serotonergic neurons, distinct from typical varicosities, and form only after prolonged increases in cytoplasmic serotonin. |
2010-09-27 |
2023-08-12 |
drosophila_melanogaster |
| Georgia Rentesi, Katerina Antoniou, Marios Marselos, Andreas Fotopoulos, Jihad Alboycharali, Maria Konstand. Long-term consequences of early maternal deprivation in serotonergic activity and HPA function in adult rat. Neuroscience letters. vol 480. issue 1. 2010-09-24. PMID:20435091. |
the aim of the present study was to clarify the long-term effects of md, on hypothalamo-pituitary-adrenal (hpa) axis activity and serotonergic (5-ht) function, in adulthood, subjects that have not been yet thoroughly investigated. |
2010-09-24 |
2023-08-12 |
human |
| Robert P Vertes, Stephanie B Linley, Walter B Hoove. Pattern of distribution of serotonergic fibers to the thalamus of the rat. Brain structure & function. vol 215. issue 1. 2010-09-23. PMID:20390296. |
it is well established that serotonergic (5-hydroxytryptamine, 5-ht) fibers, mainly originating from the dorsal and median raphe nuclei of the brainstem, distribute throughout the forebrain, most heavily to 'limbic' forebrain structures. |
2010-09-23 |
2023-08-12 |
rat |
| Robert P Vertes, Stephanie B Linley, Walter B Hoove. Pattern of distribution of serotonergic fibers to the thalamus of the rat. Brain structure & function. vol 215. issue 1. 2010-09-23. PMID:20390296. |
this pattern of 5-ht innervation indicates that serotonin/ serotonergic fibers mainly affect thalamic nuclei with connections to 'non-principal' or limbic regions of the cortex (or forebrain). |
2010-09-23 |
2023-08-12 |
rat |
| Robert P Vertes, Stephanie B Linley, Walter B Hoove. Pattern of distribution of serotonergic fibers to the thalamus of the rat. Brain structure & function. vol 215. issue 1. 2010-09-23. PMID:20390296. |
this suggests that serotonergic fibers to the thalamus may exert a significant influence on affective and cognitive functions, possibly complementing the actions of 5-ht fibers to other parts of the brain involved in emotional and cognitive behaviors. |
2010-09-23 |
2023-08-12 |
rat |
| Kazuki Nagayasu, Maiko Kitaichi, Hisashi Shirakawa, Takayuki Nakagawa, Shuji Kanek. Sustained exposure to 3,4-methylenedioxymethamphetamine induces the augmentation of exocytotic serotonin release in rat organotypic raphe slice cultures. Journal of pharmacological sciences. vol 113. issue 2. 2010-09-23. PMID:20484864. |
recently, we have reported that sustained exposure to mdma induced an augmentation of serotonin release in rat raphe serotonergic slice cultures. |
2010-09-23 |
2023-08-12 |
rat |
| Najam A Shari. Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action. Current drug targets. vol 11. issue 8. 2010-09-22. PMID:20426763. |
the eye is innervated by numerous serotonergic nerves and serotonin (5-hydroxytryptamine; 5ht) is present in the aqueous humor of animal and human eyes. |
2010-09-22 |
2023-08-12 |
human |
| Najam A Shari. Serotonin-2 receptor agonists as novel ocular hypotensive agents and their cellular and molecular mechanisms of action. Current drug targets. vol 11. issue 8. 2010-09-22. PMID:20426763. |
in an effort to delineate the role of the serotonergic system in modulating intraocular pressure (iop) within the anterior segment of the eye, extensive topical ocular dosing studies were conducted with a variety of 5ht ligands and in various animal species. |
2010-09-22 |
2023-08-12 |
human |
| Lori Asarian, Wolfgang Langhan. A new look on brain mechanisms of acute illness anorexia. Physiology & behavior. vol 100. issue 5. 2010-09-16. PMID:20394763. |
serotonin neurons in the midbrain raphe are targets of pge2, and serotonergic projections from the midbrain raphe to the hypothalamus appear to be crucial for lps anorexia. |
2010-09-16 |
2023-08-12 |
Not clear |
| Ron Kirschner, J Ward Donova. Serotonin syndrome precipitated by fentanyl during procedural sedation. The Journal of emergency medicine. vol 38. issue 4. 2010-09-13. PMID:18757161. |
use of fentanyl for procedural sedation may precipitate serotonin syndrome in patients taking ssris or other serotonergic drugs. |
2010-09-13 |
2023-08-12 |
Not clear |
| Masaki Fumoto, Tsutomu Oshima, Kiyoshi Kamiya, Hiromi Kikuchi, Yoshinari Seki, Yasushi Nakatani, Xinjun Yu, Tamami Sekiyama, Ikuko Sato-Suzuki, Hideho Arit. Ventral prefrontal cortex and serotonergic system activation during pedaling exercise induces negative mood improvement and increased alpha band in EEG. Behavioural brain research. vol 213. issue 1. 2010-09-13. PMID:20412817. |
this study evaluates a possible involvement of the prefrontal cortex (pfc) and serotonergic (5-ht) system in psychiatric and electroencephalography (eeg) changes during and after pedaling exercise (pe). |
2010-09-13 |
2023-08-12 |
human |
| C Kriegebaum, L Gutknecht, A Schmitt, K-P Lesch, A Rei. [Serotonin now: Part 1. Neurobiology and developmental genetics]. Fortschritte der Neurologie-Psychiatrie. vol 78. issue 6. 2010-09-08. PMID:20340067. |
the indolamine 5-ht belongs to the class of monoamine transmitters and can be found in the serotonergic neurons of the raphe nuclei in the brain stem. |
2010-09-08 |
2023-08-12 |
Not clear |
| C Kriegebaum, L Gutknecht, A Schmitt, K-P Lesch, A Rei. [Serotonin now: Part 1. Neurobiology and developmental genetics]. Fortschritte der Neurologie-Psychiatrie. vol 78. issue 6. 2010-09-08. PMID:20340067. |
the serotonin transporter (sert), which accomplishes the re-uptake of 5-ht into the neuron following its release in the synaptic cleft, not only has an important role in the termination of serotonergic neurotransmission but is also an important drug target for antidepressant compounds. |
2010-09-08 |
2023-08-12 |
Not clear |
| M N Modica, V Pittalà, G Romeo, L Salerno, M A Siracus. Serotonin 5-HT3 and 5-HT4 ligands: an update of medicinal chemistry research in the last few years. Current medicinal chemistry. vol 17. issue 4. 2010-09-07. PMID:20015043. |
over the last two decades, high attention was devoted to the 5-ht(3) and 5-ht(4) receptors due to their colocalization in the gastrointestinal tract and because their ligands are useful in the treatment of intestinal serotonergic system dysfunctions. |
2010-09-07 |
2023-08-12 |
Not clear |
| Olga V Alekseyenko, Carol Lee, Edward A Kravit. Targeted manipulation of serotonergic neurotransmission affects the escalation of aggression in adult male Drosophila melanogaster. PloS one. vol 5. issue 5. 2010-09-07. PMID:20520823. |
here, we generated a transgenic line that allows selective, direct manipulation of serotonergic neurons and asked whether da and 5ht have separable effects on aggression. |
2010-09-07 |
2023-08-12 |
drosophila_melanogaster |
| Nader Perroud, Elizabeth Neidhart, Brice Petit, Monique Vessaz, Térèse Laforge, Céline Relecom, Romano La Harpe, Alain Malafosse, Michel Guippon. Simultaneous analysis of serotonin transporter, tryptophan hydroxylase 1 and 2 gene expression in the ventral prefrontal cortex of suicide victims. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 153B. issue 4. 2010-09-03. PMID:20052688. |
tryptophan hydroxylase (tph), the rate limiting enzyme of serotonin biosynthesis and the serotonin transporter (slc6a4), involved in the reuptake of serotonin from the synaptic gap, play major role in serotonergic signaling. |
2010-09-03 |
2023-08-12 |
human |
| Jae K Lee, Renee Chow, Fang Xie, Sharon Y Chow, Kristine E Tolentino, Binhai Zhen. Combined genetic attenuation of myelin and semaphorin-mediated growth inhibition is insufficient to promote serotonergic axon regeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 32. 2010-09-03. PMID:20702718. |
to test redundancy within the myelin inhibitory pathway, we analyzed raphe spinal serotonergic (5-ht) axon regeneration in mice deficient in two major myelin inhibitors, nogo and mag, and their common receptor ngr1 (or ngr). |
2010-09-03 |
2023-08-12 |
mouse |
| Pamela J Davern, Michael J McKinle. Forebrain regions affected by lateral parabrachial nucleus serotonergic mechanisms that influence sodium appetite. Brain research. vol 1339. 2010-09-02. PMID:20399756. |
blockade of serotonergic receptors in the lateral parabrachial nucleus (lpbn), via bilateral injections of nonselective 5-hydroxytryptamine (5-ht)(1/2)-receptor antagonist, methysergide causes a robust sodium appetite. |
2010-09-02 |
2023-08-12 |
rat |
| Hitoshi Maeda, Takaki Ishikawa, Tomomi Michiu. [Biochemical investigation for clinical diagnosis of drug dependence]. Nihon rinsho. Japanese journal of clinical medicine. vol 68. issue 8. 2010-09-02. PMID:20715487. |
however, drug abuse is accompanied by a decrease in serotonin and the derivative in cerebrospinal fluid, suggesting central serotonergic dysfunction, that is associated with cognitive deficits, alterations in sleep architecture and neuroendocrine function, and increased impulsivity as well as an increase in the risk for aggressive behavior toward the self involving suicide. |
2010-09-02 |
2023-08-12 |
Not clear |