| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L G Harsin. The pharmacology of the neurochemical transmission in the midbrain raphe nuclei of the rat. Current neuropharmacology. vol 4. issue 4. 2010-06-10. PMID:18654635. |
serotonergic neurons in the raphe nuclei also receive noradrenergic innervation arising from the locus coeruleus and alpha-1 and alpha-2 adrenoceptors inhibited [(3)h]5-ht release in our experimental conditions. |
2010-06-10 |
2023-08-12 |
rat |
| Carolina Chavez, Marianne Hollaus, Elizabeth Scarr, Geoff Pavey, Andrea Gogos, Maarten van den Buus. The effect of estrogen on dopamine and serotonin receptor and transporter levels in the brain: an autoradiography study. Brain research. vol 1321. 2010-06-09. PMID:20079719. |
the aim of the present study was to elucidate the effect of estrogen on dopaminergic and serotonergic regulation of prepulse inhibition (ppi) by measuring its effects on the density of dopamine transporters (dat), dopamine d(1) and d(2) receptors, serotonin transporters (sert), serotonin-1a (5-ht(1a)) and 5-ht(2a) receptors using radioligand binding autoradiography. |
2010-06-09 |
2023-08-12 |
rat |
| Mona M Hegazi, Soha S Hasanei. Effects of chronic exposure to ammonia concentrations on brain monoamines and ATPases of Nile tilapia (Oreochromis niloticus). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP. vol 151. issue 4. 2010-06-08. PMID:20116455. |
however, there was a significant decrease in 5-ht, da, and ne levels, and a significant increase in both serotonergic (5-hiaa/5-ht) and dopaminergic (dopac/da) activities of fish exposed to medium tan and high tan concentrations. |
2010-06-08 |
2023-08-12 |
Not clear |
| Katsunori Kobayashi, Yumiko Ikeda, Atsushi Sakai, Nobuyuki Yamasaki, Eisuke Haneda, Tsuyoshi Miyakawa, Hidenori Suzuk. Reversal of hippocampal neuronal maturation by serotonergic antidepressants. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 18. 2010-06-08. PMID:20404165. |
our results suggest that serotonergic antidepressants can reverse the established state of neuronal maturation in the adult hippocampus, and up-regulation of 5-ht(4) receptor-mediated signaling may play a critical role in this distinct action of antidepressants. |
2010-06-08 |
2023-08-12 |
mouse |
| Bart Roelands, Romain Meeuse. Alterations in central fatigue by pharmacological manipulations of neurotransmitters in normal and high ambient temperature. Sports medicine (Auckland, N.Z.). vol 40. issue 3. 2010-06-04. PMID:20199121. |
however, several pharmacological studies attempted and failed to alter exercise capacity through changes in serotonergic neurotransmission in humans, indicating that the role of serotonin is often overrated. |
2010-06-04 |
2023-08-12 |
Not clear |
| F I Tarazi, T Moran-Gates, E H F Wong, B Henry, M Shahi. Asenapine induces differential regional effects on serotonin receptor subtypes. Journal of psychopharmacology (Oxford, England). vol 24. issue 3. 2010-06-03. PMID:18719049. |
asenapine, a novel psychopharmacologic agent being developed for the treatment of schizophrenia and bipolar disorder, has high affinity for a wide range of receptors, including the serotonergic receptors 5-ht(1a), 5-ht(1b), 5-ht(2a), 5-ht( 2b), 5-ht(2c), 5-ht(5a), 5-ht(6) and 5-ht( 7). |
2010-06-03 |
2023-08-12 |
rat |
| Maria Iordanidou, Anna Tavridou, Ioannis Petridis, Soultana Kyroglou, Loukas Kaklamanis, Dimitrios Christakidis, Vangelis G Manolopoulo. Association of polymorphisms of the serotonergic system with smoking initiation in Caucasians. Drug and alcohol dependence. vol 108. issue 1-2. 2010-06-02. PMID:20060656. |
the serotonergic system may be implicated in susceptibility to nicotine dependence as nicotine increases 5-hydroxytryptamine (5-ht) release in brain and symptoms of nicotine withdrawal may be modulated by diminished serotonergic neurotransmission. |
2010-06-02 |
2023-08-12 |
human |
| Gabriela Maria Pavan de Arruda Camargo, Luiz Antônio de Arruda Camargo, Wilson Abrão Saa. Role of serotonergic 5-HT1A and oxytocinergic receptors of the lateral septal area in sodium intake regulation. Behavioural brain research. vol 209. issue 2. 2010-06-02. PMID:20144658. |
the aim of this study was to investigate the part played by serotonergic (5-ht(1a)) and oxytocinergic receptors in the lsa in the sodium intake induced in rats by sodium depletion followed by 24h deprivation. |
2010-06-02 |
2023-08-12 |
rat |
| Gabriela Maria Pavan de Arruda Camargo, Luiz Antônio de Arruda Camargo, Wilson Abrão Saa. Role of serotonergic 5-HT1A and oxytocinergic receptors of the lateral septal area in sodium intake regulation. Behavioural brain research. vol 209. issue 2. 2010-06-02. PMID:20144658. |
serotonergic injections of 5-ht (10, 20, and 40 microg/0.2 microl) reduced 1.8% nacl solution intake, but injections (1, 2, and 4 microg/0.2 microl) of 8-oh-dpat, a 5-ht(1a) agonist, were more effective than 5-ht in reducing 1.8% nacl intake. |
2010-06-02 |
2023-08-12 |
rat |
| Gabriela Maria Pavan de Arruda Camargo, Luiz Antônio de Arruda Camargo, Wilson Abrão Saa. Role of serotonergic 5-HT1A and oxytocinergic receptors of the lateral septal area in sodium intake regulation. Behavioural brain research. vol 209. issue 2. 2010-06-02. PMID:20144658. |
these results show that 5-ht(1a) serotonergic receptors in the lsa, including some that interact with the oxytocinergic system, modulate sodium intake induced by sodium loss in rats. |
2010-06-02 |
2023-08-12 |
rat |
| Francesca Calabrese, Raffaella Molteni, Annamaria Cattaneo, Flavia Macchi, Giorgio Racagni, Massimo Gennarelli, Bart A Ellenbroek, Marco A Riv. Long-Term duloxetine treatment normalizes altered brain-derived neurotrophic factor expression in serotonin transporter knockout rats through the modulation of specific neurotrophin isoforms. Molecular pharmacology. vol 77. issue 5. 2010-05-28. PMID:20159945. |
major vulnerability genes for mood disorders are also related to the serotonergic system: one of these genes encodes for the serotonin transporter (sert), which represent a major target for the action of antidepressant drugs. |
2010-05-28 |
2023-08-12 |
rat |
| Robert R Freedma. Treatment of menopausal hot flashes with 5-hydroxytryptophan. Maturitas. vol 65. issue 4. 2010-05-27. PMID:20031347. |
selective, serotonergic, reuptake inhibitors (ssris), which increase the amount of serotonin in the synaptic gap, have shown some promise in the amelioration of hot flashes. |
2010-05-27 |
2023-08-12 |
Not clear |
| Edward D Levin, Olga A Timofeeva, Liwei Yang, Ann Petro, Ian T Ryde, Nicola Wrench, Frederic J Seidler, Theodore A Slotki. Early postnatal parathion exposure in rats causes sex-selective cognitive impairment and neurotransmitter defects which emerge in aging. Behavioural brain research. vol 208. issue 2. 2010-05-25. PMID:20015457. |
in association with the effects on cognitive performance, neonatal parathion exposure elicited widespread abnormalities in indices of serotonergic (5ht) and cholinergic synaptic function, characterized by upregulation of 5ht(2) receptors and the 5ht transporter, deficits in choline acetyltransferase activity and nicotinic cholinergic receptors, and increases in hemicholinium-3 binding to the presynaptic choline transporter. |
2010-05-25 |
2023-08-12 |
rat |
| Niklas Nordquist, Lars Orelan. Serotonin, genetic variability, behaviour, and psychiatric disorders--a review. Upsala journal of medical sciences. vol 115. issue 1. 2010-05-25. PMID:20187845. |
in this review we explore, based on recent research, the hypothesis that the dual role of serotonin as a neurotransmitter and a neurotrophic factor has a significant impact on behaviour and risk for neuropsychiatric disorders through altered development of limbic neurocircuitry involved in emotional processing, and development of the serotonergic neurons, during early brain development. |
2010-05-25 |
2023-08-12 |
monkey |
| D A Schott, J Nicolai, J E de Vries, I M L W Keularts, M E Rubio-Gozalbo, W J M Gerve. Disorder in the serotonergic system due to tryptophan hydroxylation impairment: a cause of hypothalamic syndrome? Hormone research in paediatrics. vol 73. issue 1. 2010-05-25. PMID:20190542. |
since serotonin (5-ht) modulates most of the above-mentioned homeostasis, a defect in the serotonergic system can possibly participate in this syndrome. |
2010-05-25 |
2023-08-12 |
Not clear |
| Kiyoshi Kamiya, Masaki Fumoto, Hiromi Kikuchi, Tamami Sekiyama, Yuko Mohri-Lkuzawa, Masahiro Umino, Hideho Arit. Prolonged gum chewing evokes activation of the ventral part of prefrontal cortex and suppression of nociceptive responses: involvement of the serotonergic system. Journal of medical and dental sciences. vol 57. issue 1. 2010-05-20. PMID:20437764. |
we have proposed a concept that prolonged rhythmic gum chewing causes a suppressed nociceptive flexion reflex via the serotonergic (5-ht) descending inhibitory pathway. |
2010-05-20 |
2023-08-12 |
human |
| b' Espen Walderhaug, Aryeh Isaac Herman, Andres Magnusson, Michael John Morgan, Nils Inge Landr\\xc3\\xb. The short (S) allele of the serotonin transporter polymorphism and acute tryptophan depletion both increase impulsivity in men. Neuroscience letters. vol 473. issue 3. 2010-05-17. PMID:20188795.' |
we studied the triallelic system of the serotonin transporter gene linked polymorphic region (5-httlpr) and acute manipulation of serotonin together to further delineate the mechanisms by which serotonergic neurotransmission affects impulsivity. |
2010-05-17 |
2023-08-12 |
human |
| Eun-Ho Kang, Hyun-Bo Shim, Kyung-Jeong Kim, Joo-Eon Park, In-Soo Lee, Bum-Hee Y. Platelet serotonin transporter function after short-term paroxetine treatment in patients with panic disorder. Psychiatry research. vol 176. issue 2-3. 2010-05-14. PMID:20207008. |
these results support a hypothesis of serotonergic transporter abnormalities in panic disorder, and suggest that increased k(m) values of platelet serotonin transporters parallel clinical improvement after short-term pharmacotherapy in panic disorder. |
2010-05-14 |
2023-08-12 |
human |
| Adrienne Z Ables, Raju Nagubill. Prevention, recognition, and management of serotonin syndrome. American family physician. vol 81. issue 9. 2010-05-14. PMID:20433130. |
serotonin syndrome is a potentially life-threatening condition caused by excessive serotonergic activity in the nervous system. |
2010-05-14 |
2023-08-12 |
Not clear |
| Adrienne Z Ables, Raju Nagubill. Prevention, recognition, and management of serotonin syndrome. American family physician. vol 81. issue 9. 2010-05-14. PMID:20433130. |
most reported cases of serotonin syndrome are in patients using multiple serotonergic drugs or who have had considerable exposure to a single serotonin-augmenting drug. |
2010-05-14 |
2023-08-12 |
Not clear |