| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Katharina Kittler, Thorsten Lau, Patrick Schlos. Antagonists and substrates differentially regulate serotonin transporter cell surface expression in serotonergic neurons. European journal of pharmacology. vol 629. issue 1-3. 2010-03-30. PMID:20006597. |
the serotonin transporter (sert) terminates serotonergic neurotransmission by the rapid removal of serotonin (5-hydroxytryptamine, 5-ht) from the extracellular space back into serotonergic neurons. |
2010-03-30 |
2023-08-12 |
Not clear |
| Katharina Kittler, Thorsten Lau, Patrick Schlos. Antagonists and substrates differentially regulate serotonin transporter cell surface expression in serotonergic neurons. European journal of pharmacology. vol 629. issue 1-3. 2010-03-30. PMID:20006597. |
sert therefore controls the concentration of extracellular 5-ht, and thus one mechanism to regulate the efficacy of serotonergic neurotransmission is via modulation of the density of sert molecules on the cell membrane. |
2010-03-30 |
2023-08-12 |
Not clear |
| Katharina Kittler, Thorsten Lau, Patrick Schlos. Antagonists and substrates differentially regulate serotonin transporter cell surface expression in serotonergic neurons. European journal of pharmacology. vol 629. issue 1-3. 2010-03-30. PMID:20006597. |
we have studied the effects of prolonged exposure to various selective serotonin re-uptake inhibitors (ssris), as well as cocaine and the transport substrates 5-ht and 3,4-methylenedioxy-methamphetamine (mdma), on sert cell surface expression in cultured serotonergic neurons. |
2010-03-30 |
2023-08-12 |
Not clear |
| Vanessa de Souza Moreno, Kênia C Bícego, Raphael E Szawka, Janete A Anselmo-Franci, Luciane H Gargaglion. Serotonergic mechanisms on breathing modulation in the rat locus coeruleus. Pflugers Archiv : European journal of physiology. vol 459. issue 3. 2010-03-25. PMID:19844739. |
this nucleus is densely innervated by serotonergic fibers and contains high density of serotonin (5-ht) receptors, including 5-ht(1a) and 5-ht(2). |
2010-03-25 |
2023-08-12 |
rat |
| Kevin G Broadbelt, Melissa A Barger, David S Paterson, Ingrid A Holm, Elisabeth A Haas, Henry F Krous, Hannah C Kinney, Kyriacos Markianos, Alan H Begg. Serotonin-related FEV gene variant in the sudden infant death syndrome is a common polymorphism in the African-American population. Pediatric research. vol 66. issue 6. 2010-03-22. PMID:19707175. |
an important subset of the sudden infant death syndrome (sids) is associated with multiple serotonergic (5-ht) abnormalities in regions of the medulla oblongata. |
2010-03-22 |
2023-08-12 |
mouse |
| Ryan J McLaughlin, Matthew N Hill, Boris B Gorzalk. Monoaminergic neurotransmission contributes to cannabinoid-induced activation of the hypothalamic-pituitary-adrenal axis. European journal of pharmacology. vol 624. issue 1-3. 2010-03-19. PMID:19818759. |
pre-treatment with antagonists to the serotonergic type 1a (5-ht(1a); way100635; 0.5mg/kg) and 5-ht(2a/2c) (ketanserin; 1mg/kg) receptors significantly attenuated the hu-210-induced increase in corticosterone secretion. |
2010-03-19 |
2023-08-12 |
Not clear |
| S Evelyn Stewart, Eric A Jenike, Dianne M Hezel, Denise Egan Stack, Nicholas H Dodman, Louis Shuster, Michael A Jenik. A single-blinded case-control study of memantine in severe obsessive-compulsive disorder. Journal of clinical psychopharmacology. vol 30. issue 1. 2010-03-19. PMID:20075645. |
serotonergic agents including selective serotonin reuptake inhibitors and clomipramine have provided the mainstay of ocd medication management for decades. |
2010-03-19 |
2023-08-12 |
Not clear |
| Joachim Demling, Sabine Beyer, Johannes Kornhube. To sweat or not to sweat? A hypothesis on the effects of venlafaxine and SSRIs. Medical hypotheses. vol 74. issue 1. 2010-03-16. PMID:19664885. |
theoretically, sweating can be both initiated and inhibited by the activity of selective 5-ht reuptake inhibitors (ssris), so that the noradrenergic "tone" resulting from the interaction of noradrenergic and serotonergic neurons in the various regions of the brain probably determines the degree of sweating. |
2010-03-16 |
2023-08-12 |
human |
| Tomas Björklund, Thomas Carlsson, Erik Ahlm Cederfjäll, Manolo Carta, Deniz Kiri. Optimized adeno-associated viral vector-mediated striatal DOPA delivery restores sensorimotor function and prevents dyskinesias in a model of advanced Parkinson's disease. Brain : a journal of neurology. vol 133. issue Pt 2. 2010-03-16. PMID:20129936. |
interestingly, recovery of forelimb use in the stepping test observed here was maintained even after a second lesion depleting the serotonin input to the forebrain, suggesting that the therapeutic efficacy was not solely dependent on dopamine synthesis and release from striatal serotonergic terminals. |
2010-03-16 |
2023-08-12 |
rat |
| J Amat, R M Aleksejev, E Paul, L R Watkins, S F Maie. Behavioral control over shock blocks behavioral and neurochemical effects of later social defeat. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19909791. |
is is notable for inducing a large increase in dorsal raphe nucleus (drn) serotonergic (5-ht) activity as measured by extracellular levels of 5-ht within the drn, and sd did so as well. |
2010-03-12 |
2023-08-12 |
rat |
| J-D Guo, D G Rainni. Presynaptic 5-HT(1B) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis. Neuroscience. vol 165. issue 4. 2010-03-12. PMID:19963045. |
presynaptic 5-ht(1b) receptor-mediated serotonergic inhibition of glutamate transmission in the bed nucleus of the stria terminalis. |
2010-03-12 |
2023-08-12 |
rat |
| Q Liu, M T T Wong-Rile. Postnatal changes in the expressions of serotonin 1A, 1B, and 2A receptors in ten brain stem nuclei of the rat: implication for a sensitive period. Neuroscience. vol 165. issue 1. 2010-03-11. PMID:19800944. |
as serotonin and its receptors are involved in respiratory modulation, and serotonergic abnormality is implicated in sudden infant death syndrome, we hypothesized that 5-ht receptors are significantly downregulated during the critical period. |
2010-03-11 |
2023-08-12 |
rat |
| Q Liu, M T T Wong-Rile. Postnatal changes in the expressions of serotonin 1A, 1B, and 2A receptors in ten brain stem nuclei of the rat: implication for a sensitive period. Neuroscience. vol 165. issue 1. 2010-03-11. PMID:19800944. |
thus, a significant reduction in the expression of 5-ht(1a)r, 5-ht(1b)r, and 5-ht(2a)r in multiple respiratory-related nuclei at p12 is consistent with reduced serotonergic transmission during the critical period, thereby rendering the animals less able to respond adequately to ventilatory distress. |
2010-03-11 |
2023-08-12 |
rat |
| D Alberghina, C Giannetto, E K Visser, A D Elli. Effect of diet on plasma tryptophan and serotonin in trained mares and geldings. The Veterinary record. vol 166. issue 5. 2010-03-11. PMID:20118469. |
plasma 5-ht may therefore be a good marker of serotonergic activity. |
2010-03-11 |
2023-08-12 |
Not clear |
| Kathrin Scheuch, Markus Höltje, Holger Budde, Marion Lautenschlager, Andreas Heinz, Gudrun Ahnert-Hilger, Josef Prille. Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons. Brain research. vol 1307. 2010-03-08. PMID:19840776. |
lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons. |
2010-03-08 |
2023-08-12 |
rat |
| Kathrin Scheuch, Markus Höltje, Holger Budde, Marion Lautenschlager, Andreas Heinz, Gudrun Ahnert-Hilger, Josef Prille. Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons. Brain research. vol 1307. 2010-03-08. PMID:19840776. |
in this study, we investigated the effects of lithium chloride (licl, 1 mm) on 5-ht uptake and release in primary serotonergic neurons from rat raphe nuclei. |
2010-03-08 |
2023-08-12 |
rat |
| Kathrin Scheuch, Markus Höltje, Holger Budde, Marion Lautenschlager, Andreas Heinz, Gudrun Ahnert-Hilger, Josef Prille. Lithium modulates tryptophan hydroxylase 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons. Brain research. vol 1307. 2010-03-08. PMID:19840776. |
our results suggest that lithium can modify tph2 gene expression and 5-ht release in raphe neurons, providing new insight into the serotonergic mechanisms of action of lithium. |
2010-03-08 |
2023-08-12 |
rat |
| Róbert Bódiz. [In waves' parlance: serotonin and sleep oscillations]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 11. issue 3. 2010-03-05. PMID:20128397. |
moreover, there is suggestive data for the reciprocal interactions between serotonin, neural plasticity and sleep spindling, which might provide new insights to the neuropsychopharmacological characterization of the mechanisms of action and effects of drugs acting through the serotonergic system. |
2010-03-05 |
2023-08-12 |
Not clear |
| J H Jhoo, I-Y Yoon, Y K Kim, S Chung, J-M Kim, S B Lee, T H Kim, S H Moon, S E Kim, K W Ki. Availability of brain serotonin transporters in patients with restless legs syndrome. Neurology. vol 74. issue 6. 2010-03-05. PMID:20142619. |
selective serotonin reuptake inhibitors have been associated with the risk of restless legs syndrome (rls), suggesting that dysregulation of serotonergic neurotransmission may provoke or exacerbate rls. |
2010-03-05 |
2023-08-12 |
Not clear |
| Bénédicte Amilhon, Eve Lepicard, Thibault Renoir, Raymond Mongeau, Daniela Popa, Odile Poirel, Stéphanie Miot, Christelle Gras, Alain M Gardier, Jorge Gallego, Michel Hamon, Laurence Lanfumey, Bruno Gasnier, Bruno Giros, Salah El Mestikaw. VGLUT3 (vesicular glutamate transporter type 3) contribution to the regulation of serotonergic transmission and anxiety. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 6. 2010-03-05. PMID:20147547. |
vglut3- and vmat2-positive serotonergic fibers show little or no 5-ht reuptake transporter. |
2010-03-05 |
2023-08-12 |
mouse |