| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hai-Xia Lu, Hannah Levis, Yong Liu, Terry Parke. Organotypic slices culture model for cerebellar ataxia: potential use to study Purkinje cell induction from neural stem cells. Brain research bulletin. vol 84. issue 2. 2011-07-22. PMID:21145378. |
our results show that this model could be used to assess the potential for nsc repair of the damaged cerebellum and dissect the possible underlying mechanisms by observing the interaction between nscs and purkinje cells in an easily accessible 3-d environment in vitro. |
2011-07-22 |
2023-08-12 |
rat |
| Françis Crépel, Micaela Galante, Samia Habbas, Heather McLean, Hervé Danie. Role of the vesicular transporter VGLUT3 in retrograde release of glutamate by cerebellar Purkinje cells. Journal of neurophysiology. vol 105. issue 3. 2011-07-22. PMID:21177991. |
in the cerebellum, retrograde release of glutamate (glu) by purkinje cells (pcs) participates in the control of presynaptic neurotransmitter release responsible for the late component of depolarization-induced suppression of excitation (dse), as well as for depolarization-induced potentiation of inhibition (dpi). |
2011-07-22 |
2023-08-12 |
mouse |
| Dan Rokni, Rodolfo Llinas, Yosef Yaro. The Morpho/Functional Discrepancy in the Cerebellar Cortex: Looks Alone are Deceptive. Frontiers in neuroscience. vol 2. issue 2. 2011-07-14. PMID:19225592. |
in a recent report we demonstrated that stimulation of cerebellar mossy fibers synchronously activates purkinje cells that are located directly above the site of stimulation. |
2011-07-14 |
2023-08-12 |
Not clear |
| Dan Rokni, Rodolfo Llinas, Yosef Yaro. The Morpho/Functional Discrepancy in the Cerebellar Cortex: Looks Alone are Deceptive. Frontiers in neuroscience. vol 2. issue 2. 2011-07-14. PMID:19225592. |
we found that the activated purkinje cells are arranged in a radial patch on the cerebellar surface and that this organization is independent of the integrity of the inhibitory system. |
2011-07-14 |
2023-08-12 |
Not clear |
| Michael M Yartsev, Ronit Givon-Mayo, Michael Maller, Opher Donchi. Pausing purkinje cells in the cerebellum of the awake cat. Frontiers in systems neuroscience. vol 3. 2011-07-14. PMID:19390639. |
pausing purkinje cells in the cerebellum of the awake cat. |
2011-07-14 |
2023-08-12 |
cat |
| Sergio Solinas, Thierry Nieus, Egidio D'Angel. A realistic large-scale model of the cerebellum granular layer predicts circuit spatio-temporal filtering properties. Frontiers in cellular neuroscience. vol 4. 2011-07-14. PMID:20508743. |
the way the cerebellar granular layer transforms incoming mossy fiber signals into new spike patterns to be related to purkinje cells is not yet clear. |
2011-07-14 |
2023-08-12 |
Not clear |
| Inbal Dar, Galit Yosha, Ronen Elfassy, Ronit Galron, Zhao-Qi Wang, Yosef Shiloh, Ari Barzila. Investigation of the functional link between ATM and NBS1 in the DNA damage response in the mouse cerebellum. The Journal of biological chemistry. vol 286. issue 17. 2011-07-14. PMID:21300797. |
among others, mre11/rad50/nbs1 is required for timely activation of the protein kinase atm (a-t, mutated), which is missing or inactivated in patients with a-t. understanding the molecular pathology of a-t, primarily its cardinal symptom, cerebellar degeneration, requires investigation of the dsb response in cerebellar neurons, particularly purkinje cells, which are the first to be lost in a-t patients. |
2011-07-14 |
2023-08-12 |
mouse |
| Mario F Wullimann, Thomas Mueller, Martin Distel, Andreas Babaryka, Benedikt Grothe, Reinhard W Köste. The long adventurous journey of rhombic lip cells in jawed vertebrates: a comparative developmental analysis. Frontiers in neuroanatomy. vol 5. 2011-07-14. PMID:21559349. |
regarding cerebellar development, these include a ptf1a expressing ventral cerebellar proliferation (vcp) giving rise to purkinje cells and other inhibitory cerebellar cell types, and an atoh1 expressing upper rhombic lip giving rise to an external granular layer (egl, i.e., excitatory granule cells) and an early ventral migration into the anterior rhombencephalon (cholinergic nuclei). |
2011-07-14 |
2023-08-12 |
zebrafish |
| Katja Ritz, Barbera Dc van Schaik, Marja E Jakobs, Antoine H van Kampen, Eleonora Aronica, Marina A Tijssen, Frank Baa. SGCE isoform characterization and expression in human brain: implications for myoclonus-dystonia pathogenesis? European journal of human genetics : EJHG. vol 19. issue 4. 2011-07-06. PMID:21157498. |
we show that a major brain-specific isoform is differentially expressed in the human brain with a notably high expression in the cerebellum, namely in the purkinje cells and neurons of the dentate nucleus. |
2011-07-06 |
2023-08-12 |
human |
| Lars Edvinsson, Sajedeh Eftekhari, Christopher A Salvatore, Karin Warfving. Cerebellar distribution of calcitonin gene-related peptide (CGRP) and its receptor components calcitonin receptor-like receptor (CLR) and receptor activity modifying protein 1 (RAMP1) in rat. Molecular and cellular neurosciences. vol 46. issue 1. 2011-07-05. PMID:21040789. |
our observations demonstrate that there is a rich expression of cgrp and cgrp receptor elements in the cerebellum which points towards a functional role of cgrp in cerebellar purkinje cells. |
2011-07-05 |
2023-08-12 |
rat |
| Euiseok J Kim, Kei Hori, Alex Wyckoff, Lauren K Dickel, Edmund J Koundakjian, Lisa V Goodrich, Jane E Johnso. Spatiotemporal fate map of neurogenin1 (Neurog1) lineages in the mouse central nervous system. The Journal of comparative neurology. vol 519. issue 7. 2011-07-01. PMID:21452201. |
although neurog1 lineages are largely restricted to glutamatergic neurons, there are multiple exceptions including purkinje cells and other gabaergic neurons in the cerebellum. |
2011-07-01 |
2023-08-12 |
mouse |
| Wataru Kakegawa, Yurika Miyoshi, Kenji Hamase, Shinji Matsuda, Keiko Matsuda, Kazuhisa Kohda, Kyoichi Emi, Junko Motohashi, Ryuichi Konno, Kiyoshi Zaitsu, Michisuke Yuzak. D-serine regulates cerebellar LTD and motor coordination through the δ2 glutamate receptor. Nature neuroscience. vol 14. issue 5. 2011-07-01. PMID:21460832. |
here we show that d-ser serves as an endogenous ligand for glud2 to regulate long-term depression (ltd) at synapses between parallel fibers and purkinje cells in the immature cerebellum. |
2011-07-01 |
2023-08-12 |
mouse |
| Ignacio González-Burgos, David González-Tapia, Dulce A Velázquez Zamora, Alfredo Feria-Velasco, Carlos Beas-Zárat. Guided motor training induces dendritic spine plastic changes in adult rat cerebellar purkinje cells. Neuroscience letters. vol 491. issue 3. 2011-06-30. PMID:21262320. |
dendritic spine density and proportions of the different spine types on purkinje cells was assessed in the cerebellar simple lobule, as was drebrin a expression. |
2011-06-30 |
2023-08-12 |
rat |
| Masahiko Tanak. Dendrite formation of cerebellar Purkinje cells. Neurochemical research. vol 34. issue 12. 2011-06-21. PMID:19821027. |
during postnatal cerebellar development, purkinje cells form the most elaborate dendritic trees among neurons in the brain, which have been of great interest to many investigators. |
2011-06-21 |
2023-08-12 |
Not clear |
| Osman Fikret Sonmez, Ersan Odaci, Orhan Bas, Süleyman Kapla. Purkinje cell number decreases in the adult female rat cerebellum following exposure to 900 MHz electromagnetic field. Brain research. vol 1356. 2011-06-17. PMID:20691167. |
in the presented study, the effects on the number of purkinje cells in the cerebellum of 16-week (16 weeks) old female rats were investigated following exposure to 900 mhz emf. |
2011-06-17 |
2023-08-12 |
human |
| Osman Fikret Sonmez, Ersan Odaci, Orhan Bas, Süleyman Kapla. Purkinje cell number decreases in the adult female rat cerebellum following exposure to 900 MHz electromagnetic field. Brain research. vol 1356. 2011-06-17. PMID:20691167. |
results showed that the total number of purkinje cells in the cerebellum of the emfg was significantly lower than those of cg (p<0.004) and sg (p<0.002). |
2011-06-17 |
2023-08-12 |
human |
| Miho Aizawa, Yuichi Abe, Takumi Ito, Hiroshi Handa, Hiroyuki Naw. mRNA distribution of the thalidomide binding protein cereblon in adult mouse brain. Neuroscience research. vol 69. issue 4. 2011-06-15. PMID:21241746. |
intense mrna signals were found in the hippocampus and cerebellum, especially in hippocampal pyramidal cells and purkinje cells. |
2011-06-15 |
2023-08-12 |
mouse |
| Dwight R Pierce, Abdallah Hayar, D Keith Williams, Kim Edward Ligh. Olivary climbing fiber alterations in PN40 rat cerebellum following postnatal ethanol exposure. Brain research. vol 1378. 2011-06-13. PMID:21241681. |
this study was designed to quantify the interactions between the olivary climbing fibers and the purkinje cells when the cerebellar circuits have matured. |
2011-06-13 |
2023-08-12 |
rat |
| Dwight R Pierce, Abdallah Hayar, D Keith Williams, Kim Edward Ligh. Olivary climbing fiber alterations in PN40 rat cerebellum following postnatal ethanol exposure. Brain research. vol 1378. 2011-06-13. PMID:21241681. |
mid-vermal cerebellar sections were stained with antibodies to calbindin-d28k (to visualize purkinje cells) and vesicular glutamate transporter 2 (vglut2, to visualize climbing fibers). |
2011-06-13 |
2023-08-12 |
rat |
| Taisuke Miyazaki, Masahiko Watanab. Development of an anatomical technique for visualizing the mode of climbing fiber innervation in Purkinje cells and its application to mutant mice lacking GluRδ2 and Ca(v)2.1. Anatomical science international. vol 86. issue 1. 2011-06-07. PMID:21153457. |
in the adult cerebellum, a single climbing fiber (cf) innervates proximal dendrites of purkinje cells (pcs). |
2011-06-07 |
2023-08-12 |
mouse |