| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R M Empson, W Akemann, Thomas Knöpfe. The role of the calcium transporter protein plasma membrane calcium ATPase PMCA2 in cerebellar Purkinje neuron function. Functional neurology. vol 25. issue 3. 2011-04-05. PMID:21232211. |
pmca2 is expressed at high levels in cerebellar purkinje neurons (pns) where functional integrity is essential for normal cerebellar function. |
2011-04-05 |
2023-08-12 |
mouse |
| Naoya Yamashita, Bedrich Mosinger, Arpita Roy, Mari Miyazaki, Kozue Ugajin, Fumio Nakamura, Yukio Sasaki, Kazuhiko Yamaguchi, Pappachan Kolattukudy, Yoshio Goshim. CRMP5 (collapsin response mediator protein 5) regulates dendritic development and synaptic plasticity in the cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 5. 2011-04-01. PMID:21289187. |
in cerebellar slices of crmp5(-/-) mice, the induction of long-term depression of excitatory synaptic transmission between parallel fibers and purkinje cells was deficient. |
2011-04-01 |
2023-08-12 |
mouse |
| Tiziano Zago, Umberto Pea, Gian Luca Fumagalli, Leonardo Areta, Giuliano Marzorati, Filippo Bianch. Cerebellar pathology and micturitional disorders: anatomotopographic and functional correlations. Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa italiana di ecografia urologica e nefrologica. vol 82. issue 4. 2011-03-31. PMID:21341556. |
on the basis of anatomopathological studies, also considering our 16 years long personal series (1992-2008), we were able to establish a relationship between such disorders and specific cerebellum anomalies, mostly of purkinje network. |
2011-03-31 |
2023-08-12 |
Not clear |
| Alice Wey, Veronica Martinez Cerdeno, David Pleasure, Paul S Knoepfle. c- and N-myc regulate neural precursor cell fate, cell cycle, and metabolism to direct cerebellar development. Cerebellum (London, England). vol 9. issue 4. 2011-03-28. PMID:20658325. |
granule neurons were almost absent from the myc dko cerebellum, and other cell types were relatively overrepresented, including astroglia, oligodendrocytes, and purkinje neurons. |
2011-03-28 |
2023-08-12 |
Not clear |
| Jean-Pierre Louboutin, Beverly A S Reyes, Elisabeth J Van Bockstaele, David S Straye. Gene transfer to the cerebellum. Cerebellum (London, England). vol 9. issue 4. 2011-03-28. PMID:20700772. |
flag epitope-expressing cells were seen, at all times after vector administration, principally detected in the purkinje cells of the cerebellum, identified as immunopositive for calbindin. |
2011-03-28 |
2023-08-12 |
human |
| Emmanuelle Lagrue, Hiroyuki Abe, Madakasira Lavanya, Jawida Touhami, Sylvie Bodard, Sylvie Chalon, Jean-Luc Battini, Marc Sitbon, Pierre Castelna. Regional characterization of energy metabolism in the brain of normal and MPTP-intoxicated mice using new markers of glucose and phosphate transport. Journal of biomedical science. vol 17. 2011-03-22. PMID:21129221. |
the pit2 ligand stained particularly the cerebellar purkinje cells, while glut1 labelling was mainly observed throughout the cortex, basal ganglia and cerebellar gray matter. |
2011-03-22 |
2023-08-12 |
mouse |
| K Wallace, S Veerisetty, I Paul, W May, J J Miguel-Hidalgo, W Bennet. Prenatal infection decreases calbindin, decreases Purkinje cell volume and density and produces long-term motor deficits in Sprague-Dawley rats. Developmental neuroscience. vol 32. issue 4. 2011-03-21. PMID:20948182. |
the cerebellum is involved in the control of motor functions with purkinje cells serving as the only output from the cerebellum. |
2011-03-21 |
2023-08-12 |
rat |
| K Wallace, S Veerisetty, I Paul, W May, J J Miguel-Hidalgo, W Bennet. Prenatal infection decreases calbindin, decreases Purkinje cell volume and density and produces long-term motor deficits in Sprague-Dawley rats. Developmental neuroscience. vol 32. issue 4. 2011-03-21. PMID:20948182. |
the aim of this study was to determine if iui leads to damage to purkinje cells in the developing cerebellum and if any damage is associated with decreases in calbindin and motor behaviors in surviving pups. |
2011-03-21 |
2023-08-12 |
rat |
| Steven U Walkley, Jakub Sikora, Matthew Micsenyi, Cristin Davidson, Kostantin Dobreni. Lysosomal compromise and brain dysfunction: examining the role of neuroaxonal dystrophy. Biochemical Society transactions. vol 38. issue 6. 2011-03-14. PMID:21118103. |
although neurons may be universally susceptible to nad, gabaergic neurons, particularly purkinje cells, appear most vulnerable and ataxia and related features of cerebellar dysfunction are a common outcome. |
2011-03-14 |
2023-08-12 |
Not clear |
| Fatiha Boukhtouche, Bernard Brugg, Rosine Wehrlé, Brigitte Bois-Joyeux, Jean-Louis Danan, Isabelle Dusart, Jean Marian. Induction of early Purkinje cell dendritic differentiation by thyroid hormone requires RORα. Neural development. vol 5. 2011-03-07. PMID:20663205. |
the active form (t3) of thyroid hormone (th) controls critical aspects of cerebellar development, such as migration of postmitotic neurons and terminal dendritic differentiation of purkinje cells. |
2011-03-07 |
2023-08-12 |
Not clear |
| Markus Damme, Stijn Stroobants, Steven U Walkley, Renate Lüllmann-Rauch, Rudi D'Hooge, Jens Fogh, Paul Saftig, Torben Lübke, Judith Blan. Cerebellar alterations and gait defects as therapeutic outcome measures for enzyme replacement therapy in α-mannosidosis. Journal of neuropathology and experimental neurology. vol 70. issue 1. 2011-03-07. PMID:21157375. |
in the cerebellar molecular layer, α-mannosidosis mice display clusters of activated bergman glia, infiltration of phagocytic macrophages, and accumulation of free cholesterol and gangliosides (gm1), notably in regions lacking purkinje cells. |
2011-03-07 |
2023-08-12 |
mouse |
| Thomas Sangrey, Dieter Jaege. Analysis of distinct short and prolonged components in rebound spiking of deep cerebellar nucleus neurons. The European journal of neuroscience. vol 32. issue 10. 2011-02-28. PMID:21039958. |
deep cerebellar nucleus (dcn) neurons show pronounced post-hyperpolarization rebound burst behavior, which may contribute significantly to responses to strong inhibitory inputs from cerebellar cortical purkinje cells. |
2011-02-28 |
2023-08-12 |
Not clear |
| Wolfgang Wagner, Stephan D Brenowitz, John A Hamme. Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons. Nature cell biology. vol 13. issue 1. 2011-02-28. PMID:21151132. |
extension of the endoplasmic reticulum (er) into dendritic spines of purkinje neurons is required for cerebellar synaptic plasticity and is disrupted in animals with null mutations in myo5a, the gene encoding myosin-va. we show here that myosin-va acts as a point-to-point organelle transporter to pull er as cargo into purkinje neuron spines. |
2011-02-28 |
2023-08-12 |
Not clear |
| Etienne Lonchamp, Jean-Luc Dupont, Laetitia Wioland, Raphaël Courjaret, Corinne Mbebi-Liegeois, Emmanuel Jover, Frédéric Doussau, Michel R Popoff, Jean-Louis Bossu, Jean de Barry, Bernard Poulai. Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release. PloS one. vol 5. issue 9. 2011-02-18. PMID:20941361. |
in cultured cerebellar slices, whole cell patch-clamp recordings of synaptic currents in purkinje cells revealed that et greatly stimulates both spontaneous excitatory and inhibitory activities. |
2011-02-18 |
2023-08-12 |
mouse |
| H Chen, S Dzitoyeva, H Mane. 5-Lipoxygenase in mouse cerebellar Purkinje cells. Neuroscience. vol 171. issue 2. 2011-02-17. PMID:20851170. |
we found that methylation in the sites targeted by methylation-sensitive restriction endonucleases acii and hinp1i but not bstui and hpaii was greater in dna samples obtained from a high-5-lox-expressing cerebellar region (purkinje cells) versus a low-5-lox-expressing region (the molecular cell layer), suggesting a possible epigenetic contribution to the cell-specific 5-lox expression in the cerebellum. |
2011-02-17 |
2023-08-12 |
mouse |
| H Chen, S Dzitoyeva, H Mane. 5-Lipoxygenase in mouse cerebellar Purkinje cells. Neuroscience. vol 171. issue 2. 2011-02-17. PMID:20851170. |
we propose that purkinje cell-localized 5-lox and flap expression may be involved in the cerebellar synthesis of leukotrienes and/or could influence the dicer-mediated microrna formation and processes of neuroplasticity. |
2011-02-17 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Hiromi Sakata-Haga, Yoshihiro Fuku. Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya. Brain research. vol 1343. 2011-02-15. PMID:20462503. |
the present study examined the spatial organization of tyrosine hydroxylase (th) immunopositive purkinje cells in the cerebellum of rolling mouse nagoya with reference to the distribution pattern of the cerebellar compartmentation antigen, heat shock protein 25 (hsp25). |
2011-02-15 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Hiromi Sakata-Haga, Yoshihiro Fuku. Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya. Brain research. vol 1343. 2011-02-15. PMID:20462503. |
these results revealed an alternating array of th immunopositive purkinje cell subsets with hsp25 immunopositive purkinje cells in the zebrin ii-defined transverse zone of the rolling mouse cerebellum. |
2011-02-15 |
2023-08-12 |
mouse |
| Tae-Sun Kim, Makoto Kawaguchi, Mitsuko Suzuki, Cha-Gyun Jung, Kiyofumi Asai, Yuta Shibamoto, Martin F Lavin, Kum Kum Khanna, Yutaka Miur. The ZFHX3 (ATBF1) transcription factor induces PDGFRB, which activates ATM in the cytoplasm to protect cerebellar neurons from oxidative stress. Disease models & mechanisms. vol 3. issue 11-12. 2011-02-14. PMID:20876357. |
it is important to consider dcn of the cerebellum in the etiology of a-t, because these neurons are directly innervated by purkinje cells, which are progressively lost in a-t. |
2011-02-14 |
2023-08-12 |
Not clear |
| Koji Tanabe, Shuichi Kani, Takashi Shimizu, Young-Ki Bae, Takaya Abe, Masahiko Hib. Atypical protein kinase C regulates primary dendrite specification of cerebellar Purkinje cells by localizing Golgi apparatus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 50. 2011-02-09. PMID:21159968. |
we used the zebrafish cerebellum to investigate the mechanisms by which purkinje cells acquire these characteristics. |
2011-02-09 |
2023-08-12 |
zebrafish |