| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Zappalà, R Parenti, F La Delia, V Cicirata, F Cicirat. Expression of connexin57 in mouse development and in harmaline-tremor model. Neuroscience. vol 171. issue 1. 2011-02-02. PMID:20849935. |
the expression of cx57 in adult life (studied at p28, by in situ hybridization and immunohistochemical analysis) concerned few regions of the brain stem (inferior olive, lateral reticular nucleus and motor trigeminal nucleus), the cerebellum (purkinje cells and cerebellar nuclei) and the spinal cord (alpha-motoneurons). |
2011-02-02 |
2023-08-12 |
mouse |
| Michisuke Yuzak. Synapse formation and maintenance by C1q family proteins: a new class of secreted synapse organizers. The European journal of neuroscience. vol 32. issue 2. 2011-01-25. PMID:20646056. |
the delta2 glutamate receptor (glud2), which is predominantly expressed in purkinje cells, plays similar critical roles in the cerebellum. |
2011-01-25 |
2023-08-12 |
Not clear |
| Ioannis A Mavroudis, Dimitrios F Fotiou, Luc F Adipepe, Marina G Manani, Samuel D Njau, Dimitrios Psaroulis, Vasiliki G Costa, Stavros J Baloyanni. Morphological changes of the human purkinje cells and deposition of neuritic plaques and neurofibrillary tangles on the cerebellar cortex of Alzheimer's disease. American journal of Alzheimer's disease and other dementias. vol 25. issue 7. 2011-01-24. PMID:20870670. |
although typical neuritic plaques were not seen in the cerebellar cortex and the diffuse plaques found in the cerebellum in far smaller proportion than plaques in the prefrontal and parietal cortices of the same cases, golgi impregnation technique revealed a loss of purkinje cells and a marked decrease in the density of dendritic arborization. |
2011-01-24 |
2023-08-12 |
human |
| Jerí L Bryant, John D Boughter, Suzhen Gong, Mark S LeDoux, Detlef H Hec. Cerebellar cortical output encodes temporal aspects of rhythmic licking movements and is necessary for normal licking frequency. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20597972. |
however, what role the cerebellum has in licking behavior and whether licking is represented in the high-frequency simple spike output of purkinje cells remains unknown. |
2011-01-13 |
2023-08-12 |
mouse |
| Jonathan Jones, Jesús Jaramillo-Merchán, Carlos Bueno, Diego Pastor, Maricarmen Viso-León, Salvador Martíne. Mesenchymal stem cells rescue Purkinje cells and improve motor functions in a mouse model of cerebellar ataxia. Neurobiology of disease. vol 40. issue 2. 2011-01-12. PMID:20638477. |
of these, cerebellar ataxia is a group of disorders characterized by the degeneration of the cerebellum, particularly the purkinje cells, responsible for motor coordination and control of the motor functions. |
2011-01-12 |
2023-08-12 |
mouse |
| Jonathan Jones, Jesús Jaramillo-Merchán, Carlos Bueno, Diego Pastor, Maricarmen Viso-León, Salvador Martíne. Mesenchymal stem cells rescue Purkinje cells and improve motor functions in a mouse model of cerebellar ataxia. Neurobiology of disease. vol 40. issue 2. 2011-01-12. PMID:20638477. |
to analyze the possibility of using bone marrow-derived mesenchymal stem cells in treating ataxia, we transplanted these cells in the cerebellum of newborn lurcher mutant mice, a very aggressive mouse model characterized by the selective early post-natal death of purkinje cells in the cerebellum. |
2011-01-12 |
2023-08-12 |
mouse |
| Jonathan Jones, Jesús Jaramillo-Merchán, Carlos Bueno, Diego Pastor, Maricarmen Viso-León, Salvador Martíne. Mesenchymal stem cells rescue Purkinje cells and improve motor functions in a mouse model of cerebellar ataxia. Neurobiology of disease. vol 40. issue 2. 2011-01-12. PMID:20638477. |
histological analysis of the cerebellum indicated that the donor cells had migrated throughout the cerebellum, as well as a significant increase in the number of purkinje cells. |
2011-01-12 |
2023-08-12 |
mouse |
| Changzheng Zhang, Qingfeng Zhu, Tianmiao Hu. Aging of cerebellar Purkinje cells. Cell and tissue research. vol 341. issue 3. 2011-01-12. PMID:20652318. |
cerebellar purkinje cells (pcs), the sole output neurons in the cerebellar cortex, play an important role in the cerebellar circuit. |
2011-01-12 |
2023-08-12 |
Not clear |
| Takaki Miyata, Yuichi Ono, Mayumi Okamoto, Makoto Masaoka, Akira Sakakibara, Ayano Kawaguchi, Mitsuhiro Hashimoto, Masaharu Ogaw. Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural development. vol 5. 2011-01-11. PMID:20809939. |
migration, early axonogenesis, and reelin-dependent layer-forming behavior of early/posterior-born purkinje cells in the developing mouse lateral cerebellum. |
2011-01-11 |
2023-08-12 |
mouse |
| Takaki Miyata, Yuichi Ono, Mayumi Okamoto, Makoto Masaoka, Akira Sakakibara, Ayano Kawaguchi, Mitsuhiro Hashimoto, Masaharu Ogaw. Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural development. vol 5. 2011-01-11. PMID:20809939. |
cerebellar corticogenesis begins with the assembly of purkinje cells into the purkinje plate (pp) by embryonic day 14.5 (e14.5) in mice. |
2011-01-11 |
2023-08-12 |
mouse |
| Hitoshi Mochizuki, Yoshikazu Ugaw. [Cerebellar ataxic gait]. Brain and nerve = Shinkei kenkyu no shinpo. vol 62. issue 11. 2011-01-03. PMID:21068457. |
the main components of the cerebellar circuit are 2 types of neurons, i.e., the purkinje cells and granule cells and 3 types of fibers, i.e., mossy fibers, climbing fibers (cerebellar afferent fibers), and parallel fibers (axons of granule cells) theoretically, cerebellar ataxia is considered to be caused by any lesions that develop within this circuit. |
2011-01-03 |
2023-08-12 |
Not clear |
| Nadezhda B Boneva, Yoshimi Mori, Desislav B Kaplamadzhiev, Hiromu Kikuchi, Hong Zhu, Mitsuru Kikuchi, Anton B Tonchev, Tetsumori Yamashim. Differential expression of FABP 3, 5, 7 in infantile and adult monkey cerebellum. Neuroscience research. vol 68. issue 2. 2010-12-21. PMID:20620177. |
immunohistochemical analysis showed that cerebellar fabp3-positive cells were purkinje cells and bergmann glia. |
2010-12-21 |
2023-08-12 |
monkey |
| Nadezhda B Boneva, Yoshimi Mori, Desislav B Kaplamadzhiev, Hiromu Kikuchi, Hong Zhu, Mitsuru Kikuchi, Anton B Tonchev, Tetsumori Yamashim. Differential expression of FABP 3, 5, 7 in infantile and adult monkey cerebellum. Neuroscience research. vol 68. issue 2. 2010-12-21. PMID:20620177. |
in the adult cerebellum, fabp7 was expressed in purkinje cells and basket interneurons, while in the infantile cerebellum it was also found in bergmann glia. |
2010-12-21 |
2023-08-12 |
monkey |
| C Fernando Valenzuela, Britta Lindquist, Paula A Zamudio-Bulcoc. A review of synaptic plasticity at Purkinje neurons with a focus on ethanol-induced cerebellar dysfunction. International review of neurobiology. vol 91. 2010-12-21. PMID:20813248. |
a review of synaptic plasticity at purkinje neurons with a focus on ethanol-induced cerebellar dysfunction. |
2010-12-21 |
2023-08-12 |
Not clear |
| D R Pierce, A Hayar, D K Williams, K E Ligh. Developmental alterations in olivary climbing fiber distribution following postnatal ethanol exposure in the rat. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20542091. |
ethanol exposure during postnatal days (pn) 4-6 in rats alters cerebellar development resulting in significant loss of purkinje cells. |
2010-12-16 |
2023-08-12 |
rat |
| D R Pierce, A Hayar, D K Williams, K E Ligh. Developmental alterations in olivary climbing fiber distribution following postnatal ethanol exposure in the rat. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20542091. |
mid-vermal cerebellar sections were stained with antibodies to calbindin-d28k (to visualize purkinje cells) and vesicular glutamate transporter 2 (vglut2, to visualize climbing fibers). |
2010-12-16 |
2023-08-12 |
rat |
| M J Urbanski, F E Kovacs, B Szab. Endocannabinoid-mediated synaptically evoked suppression of GABAergic transmission in the cerebellar cortex. Neuroscience. vol 169. issue 3. 2010-12-16. PMID:20553815. |
spontaneous postsynaptic currents (spscs) were recorded with patch-clamp techniques in purkinje cells in mouse cerebellar brain slices. |
2010-12-16 |
2023-08-12 |
mouse |
| Claire Piochon, Carole Levenes, Gen Ohtsuki, Christian Hanse. Purkinje cell NMDA receptors assume a key role in synaptic gain control in the mature cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068337. |
a classic view in cerebellar physiology holds that purkinje cells do not express functional nmda receptors and that, therefore, postsynaptic nmda receptors are not involved in the induction of long-term depression (ltd) at parallel fiber (pf) to purkinje cell synapses. |
2010-12-13 |
2023-08-12 |
mouse |
| Gang Xie, John Harrison, Steven J Clapcote, Yun Huang, Jin-Yi Zhang, Lu-Yang Wang, John C Rode. A new Kv1.2 channelopathy underlying cerebellar ataxia. The Journal of biological chemistry. vol 285. issue 42. 2010-12-07. PMID:20696761. |
patch clamp recordings from cerebellar slices revealed an increased frequency and amplitude of spontaneous gabaergic inhibitory postsynaptic currents and reduced action potential firing frequency in purkinje cells, suggesting that an increase in gaba release from basket cells is involved in the motor incoordination in pgu mice. |
2010-12-07 |
2023-08-12 |
mouse |
| Manisha Nautiyal, Andrew J Sweatt, James A MacKenzie, R Mark Payne, Sylvia Szucs, Reuben Matalon, Reidar Wallin, Susan M Hutso. Neuronal localization of the mitochondrial protein NIPSNAP1 in rat nervous system. The European journal of neuroscience. vol 32. issue 4. 2010-11-30. PMID:20646061. |
results show that nipsnap1 is expressed exclusively in neurons including pyramidal neurons in the cerebral cortex, purkinje neurons in the cerebellum and motor neurons in the spinal cord. |
2010-11-30 |
2023-08-12 |
mouse |