| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nigar Vardi, Hakan Parlakpinar, Burhan Ate. Beneficial effects of chlorogenic acid on methotrexate-induced cerebellar Purkinje cell damage in rats. Journal of chemical neuroanatomy. vol 43. issue 1. 2012-07-19. PMID:21946024. |
mtx caused severe loss of purkinje cells and apoptotic cell death in the cerebellum. |
2012-07-19 |
2023-08-12 |
rat |
| In Youb Chang, Takbum Ohn, Gil Seok Ko, Young Yoon, Jung Woo Kim, Sang Pil Yoo. Immunolocalization of steroidogenic acute regulatory protein-related lipid transfer (START) domain-containing proteins in the developing cerebellum of normal and hypothyroid rats. Journal of chemical neuroanatomy. vol 43. issue 1. 2012-07-19. PMID:22024186. |
as shown by calbindin d-28k immunostaining, the developing cerebellar cytoarchitecture and purkinje cells were affected by ptu-induced hypothyroidism as compared to control rats. |
2012-07-19 |
2023-08-12 |
rat |
| Ujjwal K Rout, Nils K Mungan, Dirk M Dhossch. Presence of GAD65 autoantibodies in the serum of children with autism or ADHD. European child & adolescent psychiatry. vol 21. issue 3. 2012-07-16. PMID:22323074. |
the serum of 60% of autistic and 53% of adhd patients reacted with purkinje neurons in mouse cerebellum. |
2012-07-16 |
2023-08-12 |
mouse |
| Josef P Kapfhammer, Olivia S Gugge. The analysis of purkinje cell dendritic morphology in organotypic slice cultures. Journal of visualized experiments : JoVE. issue 61. 2012-07-13. PMID:22473312. |
we present here a short, reliable and easy protocol for viewing and analyzing the dendritic morphology of purkinje cells grown in organotypic cerebellar slice cultures. |
2012-07-13 |
2023-08-12 |
mouse |
| Michael Piper, Lachlan Harris, Guy Barry, Yee Hsieh Evelyn Heng, Celine Plachez, Richard M Gronostajski, Linda J Richard. Nuclear factor one X regulates the development of multiple cellular populations in the postnatal cerebellum. The Journal of comparative neurology. vol 519. issue 17. 2012-07-03. PMID:21800304. |
using nfix⁻/⁻ mice, we demonstrate that the development of cerebellar granule neurons and purkinje cells within the postnatal cerebellum is delayed in the absence of this transcription factor. |
2012-07-03 |
2023-08-12 |
mouse |
| Muzammil Ahmad Khan, Muhammad Arshad Rafiq, Abdul Noor, Shobbir Hussain, Joana V Flores, Verena Rupp, Akshita K Vincent, Roland Malli, Ghazanfar Ali, Falak Sher Khan, Gisele E Ishak, Dan Doherty, Rosanna Weksberg, Muhammad Ayub, Christian Windpassinger, Shahnaz Ibrahim, Michaela Frye, Muhammad Ansar, John B Vincen. Mutation in NSUN2, which encodes an RNA methyltransferase, causes autosomal-recessive intellectual disability. American journal of human genetics. vol 90. issue 5. 2012-06-25. PMID:22541562. |
in mouse brains, we show that nsun2 localizes to the nucleolus of purkinje cells in the cerebellum. |
2012-06-25 |
2023-08-12 |
mouse |
| Alexander Riechers, Anja Katrin Bosserhof. Pitfalls in immunohistochemistry--a recent example. International journal of clinical and experimental pathology. vol 5. issue 2. 2012-06-21. PMID:22400073. |
a recently published study [1] claims that the protein mia (melanoma inhibitory activity) is expressed in purkinje cells in the cerebellum. |
2012-06-21 |
2023-08-12 |
Not clear |
| De-Hyung Lee, Katharina Kubera, Bastian Rosenthal, Barbara Kaltschmidt, Christian Kaltschmidt, Ralf Gold, Ralf A Linke. Neuronal NF-κB ablation does not influence neuro-axonal degeneration in experimental autoimmune demyelination. Journal of neuroimmunology. vol 246. issue 1-2. 2012-06-19. PMID:22475633. |
a calcium calmodulin kinase ii promoter-driven tetracycline transactivator is employed to regulate the expression of a human transdominant negative iκb-alpha mutant in the basal forebrain and selected neuronal subpopulations in the cerebellum and spinal cord including cerebellar purkinje cells and spinal cord alpha motorneurons. |
2012-06-19 |
2023-08-12 |
mouse |
| W M Chan, Jie Xu, Ming Fan, Yanling Jiang, Therese Y M Tsui, Maria S M Wai, W P Lam, D T Ye. Downregulation in the human and mice cerebella after ketamine versus ketamine plus ethanol treatment. Microscopy research and technique. vol 75. issue 3. 2012-06-15. PMID:21809417. |
fewer purkinje cells were observed in the cerebellar sections of ketamine treated mice under silver staining. |
2012-06-15 |
2023-08-12 |
mouse |
| Eriko Fujita, Yuko Tanabe, Beat A Imhof, Mariko Y Momoi, Takashi Momo. Cadm1-expressing synapses on Purkinje cell dendrites are involved in mouse ultrasonic vocalization activity. PloS one. vol 7. issue 1. 2012-06-11. PMID:22272290. |
cadm1 was preferentially localized to the apical-distal portion of the dendritic arbor of purkinje cells in the molecular layer of wild-type pups, and vglut1 level decreased in the cerebellum of cadm1 ko mice. |
2012-06-11 |
2023-08-12 |
mouse |
| Yong-Hwan Kim, Anand Rane, Stephanie Lussier, Julie K Anderse. Lithium protects against oxidative stress-mediated cell death in α-synuclein-overexpressing in vitro and in vivo models of Parkinson's disease. Journal of neuroscience research. vol 89. issue 10. 2012-06-04. PMID:21710541. |
lithium feeding (0.255% lithium chloride) of 9-month-old pan-neuronal α-synuclein transgenic mice over a 3-month period was also sufficient to prevent accumulation of oxidized/nitrated α-synuclein as a consequence of chronic paraquat/maneb administration in multiple brain regions, including the glomerular layer, mitral cells, and the granule cell layer of the olfactory bulb (ob), striatum, substantia nigra pars compacta (snpc) and purkinje cells of the cerebellum. |
2012-06-04 |
2023-08-12 |
mouse |
| Etienne Lonchamp, Frédéric Gambino, Jean Luc Dupont, Frédéric Doussau, Antoine Valera, Bernard Poulain, Jean-Louis Boss. Pre and post synaptic NMDA effects targeting Purkinje cells in the mouse cerebellar cortex. PloS one. vol 7. issue 1. 2012-06-04. PMID:22276158. |
in the mouse cerebellum, beside a developmental switch between nr2b and nr2a/c subunits in granule cells, functional postsynaptic nmda receptors are seen in purkinje cells of neonate and adult but not juvenile rat and mice. |
2012-06-04 |
2023-08-12 |
mouse |
| Etienne Lonchamp, Frédéric Gambino, Jean Luc Dupont, Frédéric Doussau, Antoine Valera, Bernard Poulain, Jean-Louis Boss. Pre and post synaptic NMDA effects targeting Purkinje cells in the mouse cerebellar cortex. PloS one. vol 7. issue 1. 2012-06-04. PMID:22276158. |
using mouse cerebellar cultures and patch-clamp recordings we show that nmda facilitates glutamate release onto purkinje cells in young cultures via a presynaptic mechanism, whereas nmda activates extrasynaptic receptors in purkinje cells recorded in old cultures. |
2012-06-04 |
2023-08-12 |
mouse |
| Toshihiro Nomura, Wataru Kakegawa, Shinji Matsuda, Kazuhisa Kohda, Jun Nishiyama, Takao Takahashi, Michisuke Yuzak. Cerebellar long-term depression requires dephosphorylation of TARP in Purkinje cells. The European journal of neuroscience. vol 35. issue 3. 2012-05-29. PMID:22239345. |
cerebellar long-term depression requires dephosphorylation of tarp in purkinje cells. |
2012-05-29 |
2023-08-12 |
Not clear |
| Elizabeth D Buttermore, Claire Piochon, Michael L Wallace, Benjamin D Philpot, Christian Hansel, Manzoor A Bha. Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 14. 2012-05-29. PMID:22492029. |
pinceau organization in the cerebellum requires distinct functions of neurofascin in purkinje and basket neurons during postnatal development. |
2012-05-29 |
2023-08-12 |
mouse |
| Elizabeth D Buttermore, Claire Piochon, Michael L Wallace, Benjamin D Philpot, Christian Hansel, Manzoor A Bha. Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 14. 2012-05-29. PMID:22492029. |
basket axon collaterals synapse onto the purkinje soma/axon initial segment (ais) area to form specialized structures, the pinceau, which are critical for normal cerebellar function. |
2012-05-29 |
2023-08-12 |
mouse |
| Elizabeth D Buttermore, Claire Piochon, Michael L Wallace, Benjamin D Philpot, Christian Hansel, Manzoor A Bha. Pinceau organization in the cerebellum requires distinct functions of neurofascin in Purkinje and basket neurons during postnatal development. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 14. 2012-05-29. PMID:22492029. |
thus, cerebellar pinceau organization requires coordinated mechanisms involving specific nfasc functions in both purkinje and basket neurons. |
2012-05-29 |
2023-08-12 |
mouse |
| Pervin K Iseri, Ayse Karson, Kemal M Gullu, Ozlem Akman, Sibel Kokturk, Melda Yardýmoglu, Sarp Erturk, Nurbay Ate. The effect of memantine in harmaline-induced tremor and neurodegeneration. Neuropharmacology. vol 61. issue 4. 2012-05-25. PMID:21640732. |
harmaline caused neuronal cell loss and caspase-3 mediated apoptosis in cerebellar granular and purkinje cells as well as the inferior olivary neurons. |
2012-05-25 |
2023-08-12 |
rat |
| S L L Kueh, J Dempster, S I Head, J W Morle. Reduced postsynaptic GABAA receptor number and enhanced gaboxadol induced change in holding currents in Purkinje cells of the dystrophin-deficient mdx mouse. Neurobiology of disease. vol 43. issue 3. 2012-05-21. PMID:21601636. |
in the cerebellum, dystrophin is normally localized at the postsynaptic membrane of gabaergic synapses on purkinje cells. |
2012-05-21 |
2023-08-12 |
mouse |
| Alexander R Bottini, Richard A Gatti, Martin Wirenfeldt, Harry V Vinter. Heterotopic Purkinje cells in ataxia-telangiectasia. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 32. issue 1. 2012-05-17. PMID:21978196. |
the most prominent and consistent neuropathologic finding in the disorder is cerebellar cortical degeneration involving significant loss of granule and purkinje cells. |
2012-05-17 |
2023-08-12 |
Not clear |