| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Akira Iizuka, Kazuhiro Nakamura, Hirokazu Hira. Long-term oral administration of the NMDA receptor antagonist memantine extends life span in spinocerebellar ataxia type 1 knock-in mice. Neuroscience letters. vol 592. 2015-07-15. PMID:25725171. |
furthermore, memantine significantly suppressed the loss of purkinje cells in the cerebellum and motor neurons in the dorsal motor nucleus of the vagus, which are critical for motor function and parasympathetic function, respectively. |
2015-07-15 |
2023-08-13 |
mouse |
| Takako Usuki, Hiromichi Sakai, Takao Shionoya, Naruki Sato, Fumio Sakan. Expression and localization of type II diacylglycerol kinase isozymes δ and η in the developing mouse brain. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 63. issue 1. 2015-07-08. PMID:25362140. |
a substantial amount of dgkη (η1/η2) was detected in layers ii-vi of the cerebral cortex, ca1 and ca2 regions and dentate gyrus of the hippocampus, mitral cell and glomerular layers of the olfactory bulb, and purkinje cells in the cerebellum of 1- to 32-week-old mice. |
2015-07-08 |
2023-08-13 |
mouse |
| Akira Katoh, Soon-Lim Shin, Rhea R Kimpo, Jacob M Rinaldi, Jennifer L Raymon. Purkinje cell responses during visually and vestibularly driven smooth eye movements in mice. Brain and behavior. vol 5. issue 3. 2015-07-08. PMID:25642393. |
we analyzed the contribution of vestibular and nonvestibular signals to the responses of individual purkinje cells in the cerebellar flocculus of mice. |
2015-07-08 |
2023-08-13 |
mouse |
| Pavitra S Ramachandran, Ryan L Boudreau, Kellie A Schaefer, Albert R La Spada, Beverly L Davidso. Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7. Molecular therapy : the journal of the American Society of Gene Therapy. vol 22. issue 9. 2015-07-06. PMID:24930601. |
the most striking feature is the degeneration of purkinje neurons of the cerebellum caused by the presence of polyglutamine-expanded ataxin-7. |
2015-07-06 |
2023-08-13 |
mouse |
| Ka Hung Lee, Paul J Mathews, Alexander M B Reeves, Katrina Y Choe, Shekib A Jami, Raul E Serrano, Thomas S Oti. Circuit mechanisms underlying motor memory formation in the cerebellum. Neuron. vol 86. issue 2. 2015-06-30. PMID:25843404. |
to determine how cerebellar activity relates to movement and motor learning, we used optogenetics to manipulate spontaneously firing purkinje neurons (pns) in mouse simplex lobe. |
2015-06-30 |
2023-08-13 |
mouse |
| Stavros J Baloyanni. Golgi apparatus and protein trafficking in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:24946873. |
in this study, the morphological and morphometric alterations of the golgi apparatus (ga) are described in the purkinje cells of the cerebellum in twenty ad brains, studied with electron microscopy. |
2015-06-29 |
2023-08-13 |
Not clear |
| Stavros J Baloyanni. Golgi apparatus and protein trafficking in Alzheimer's disease. Journal of Alzheimer's disease : JAD. vol 42 Suppl 3. 2015-06-29. PMID:24946873. |
in ad cases, described in this study, an obvious fragmentation of the cisternae of ga was observed in the purkinje cells of the vermis and the cerebellar hemispheres. |
2015-06-29 |
2023-08-13 |
Not clear |
| Farzaneh Najafi, Andrea Giovannucci, Samuel S-H Wang, Javier F Medin. Coding of stimulus strength via analog calcium signals in Purkinje cell dendrites of awake mice. eLife. vol 3. 2015-06-26. PMID:25205669. |
the climbing fiber input to purkinje cells acts as a teaching signal by triggering a massive influx of dendritic calcium that marks the occurrence of instructive stimuli during cerebellar learning. |
2015-06-26 |
2023-08-13 |
mouse |
| Chuanqing Wu, Mei Yang, Juan Li, Chengbing Wang, Ting Cao, Kaixiong Tao, Baolin Wan. Talpid3-binding centrosomal protein Cep120 is required for centriole duplication and proliferation of cerebellar granule neuron progenitors. PloS one. vol 9. issue 9. 2015-06-18. PMID:25251415. |
gnp proliferation and thus cerebellar development require sonic hedgehog (shh) secreted from purkinje cells. |
2015-06-18 |
2023-08-13 |
mouse |
| Sergio Verduzco-Flore. Stochastic Synchronization in Purkinje Cells with Feedforward Inhibition Could Be Studied with Equivalent Phase-Response Curves. Journal of mathematical neuroscience. vol 5. issue 1. 2015-06-18. PMID:26084702. |
simple-spike synchrony between purkinje cells projecting to a common neuron in the deep cerebellar nucleus is emerging as an important factor in the encoding of output information from cerebellar cortex. |
2015-06-18 |
2023-08-13 |
Not clear |
| Ludovico Silvestri, Marco Paciscopi, Paolo Soda, Filippo Biamonte, Giulio Iannello, Paolo Frasconi, Francesco S Pavon. Quantitative neuroanatomy of all Purkinje cells with light sheet microscopy and high-throughput image analysis. Frontiers in neuroanatomy. vol 9. 2015-06-15. PMID:26074783. |
in this paper, we apply recent advances in optical microscopy and image analysis to characterize the spatial distribution of purkinje cells (pcs) across the whole cerebellum. |
2015-06-15 |
2023-08-13 |
mouse |
| Manshu Tang, Anwer Siddiqi, Benjamin Witt, Tatiana Yuzyuk, Britt Johnson, Nisa Fraser, Wyman Chen, Rafael Rascon, Xue Yin, Harish Goli, Olaf A Bodamer, Kent La. Subfertility and growth restriction in a new galactose-1 phosphate uridylyltransferase (GALT) - deficient mouse model. European journal of human genetics : EJHG. vol 22. issue 10. 2015-06-11. PMID:24549051. |
cerebral edema, abnormal changes in the purkinje and the outer granular cell layers of the cerebellum, as well as lower blood gsh/gssg ratio were identified in the galactose-intoxicated pups. |
2015-06-11 |
2023-08-12 |
mouse |
| Rodrigo S Hernández, Rocío Sarasa, Adolfo Toledano, Juan J Badiola, Marta Monzó. Morphological approach to assess the involvement of astrocytes in prion propagation. Cell and tissue research. vol 358. issue 1. 2015-06-11. PMID:24931403. |
moreover, cerebellar lesions mainly associated to purkinje cells that have not previously been reported in animal prion diseases in natural transmission are described here. |
2015-06-11 |
2023-08-13 |
Not clear |
| Lu Yu, Toshiharu Iwasaki, Ming Xu, Ronny Lesmana, Yu Xiong, Noriaki Shimokawa, William W Chin, Noriyuki Koibuch. Aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar Purkinje cells. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25603044. |
aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar purkinje cells. |
2015-06-11 |
2023-08-13 |
mouse |
| Lu Yu, Toshiharu Iwasaki, Ming Xu, Ronny Lesmana, Yu Xiong, Noriaki Shimokawa, William W Chin, Noriyuki Koibuch. Aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar Purkinje cells. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25603044. |
to study the role of the thyroid hormone (th) in cerebellar development, we generated transgenic mice expressing a dominant-negative th receptor (tr) in cerebellar purkinje cells. |
2015-06-11 |
2023-08-13 |
mouse |
| Lu Yu, Toshiharu Iwasaki, Ming Xu, Ronny Lesmana, Yu Xiong, Noriaki Shimokawa, William W Chin, Noriyuki Koibuch. Aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar Purkinje cells. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25603044. |
the transgene was specifically expressed in purkinje cells in the postnatal cerebellum. |
2015-06-11 |
2023-08-13 |
mouse |
| Lu Yu, Toshiharu Iwasaki, Ming Xu, Ronny Lesmana, Yu Xiong, Noriaki Shimokawa, William W Chin, Noriyuki Koibuch. Aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar Purkinje cells. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25603044. |
these results indicate that th action through its binding to tr in purkinje cells is required for the normal cerebellar development. |
2015-06-11 |
2023-08-13 |
mouse |
| Lu Yu, Toshiharu Iwasaki, Ming Xu, Ronny Lesmana, Yu Xiong, Noriaki Shimokawa, William W Chin, Noriyuki Koibuch. Aberrant cerebellar development of transgenic mice expressing dominant-negative thyroid hormone receptor in cerebellar Purkinje cells. Endocrinology. vol 156. issue 4. 2015-06-11. PMID:25603044. |
th action through tr in purkinje cells is also important for the development of other subsets of cerebellar cells such as granule cells and oligodendrocytes. |
2015-06-11 |
2023-08-13 |
mouse |
| V Z Han, G Magnus, Y Zhang, A D Wei, E E Turne. Bidirectional modulation of deep cerebellar nuclear cells revealed by optogenetic manipulation of inhibitory inputs from Purkinje cells. Neuroscience. vol 277. 2015-06-08. PMID:25020121. |
bidirectional modulation of deep cerebellar nuclear cells revealed by optogenetic manipulation of inhibitory inputs from purkinje cells. |
2015-06-08 |
2023-08-13 |
mouse |
| V Z Han, G Magnus, Y Zhang, A D Wei, E E Turne. Bidirectional modulation of deep cerebellar nuclear cells revealed by optogenetic manipulation of inhibitory inputs from Purkinje cells. Neuroscience. vol 277. 2015-06-08. PMID:25020121. |
in the mammalian cerebellum, deep cerebellar nuclear (dcn) cells convey all information from cortical purkinje cells (pcs) to premotor nuclei and other brain regions. |
2015-06-08 |
2023-08-13 |
mouse |